Inhibiteurs

MCAAD-3, a near-infrared Aβ imaging probe, exhibits blood-brain barrier permeability and strong affinity for Aβ polymers (Ki >106 nM).

LH1306 inhibits PD-1/PD-L1 interaction, IC50: 25 nM (HTRF assay); boosts Jurkat cell activation, EC50: 334-4,214 nM.

α-conotoxin GI, a conopeptide isolated from the venom of the cone snail Conus geographus, is a competitive antagonist of the muscle-type nicotinic acetylcholine

SHP2 degrader-1: highly efficient, induces SHP2 degradation & cell apoptosis, shows promise in SHP2-related disease research.

Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.

CAY10735: Anticancer agent; inhibits growth/migration in various cancer cells; reduces tumor in mouse models. IC50=0.674-11.56μM.

Darobactin is an antibiotic effective against critical Gram-negative pathogens, demonstrating activity both in vitro and in animal infection models [1].

Activates Notch pathway, boosts NSC self-renewal and neurogenesis, enhances mice memory.

Sirtratumab vedotin (ASG15-ME) is an antibody-drug conjugate (ADC) that links a SLITRK6-specific human gamma 2 antibody (Igγ2) to the microtubule disruption agent monomethyl auristatin E (MMAE) through a protease-cleavable linker [1].

Firefly Luciferase circRNA, originally isolated from Photinus pyralis (Firefly), expresses a luciferase protein and serves as an optimal marker for monitoring

ER degrader 3 targets estrogen receptor, key in cell regulation, potential for cancer research.

gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.

(5R)-Platyphyllone has a wide range of applications in life science related research.

Spirolingzhine D is a useful organic compound for research related to life sciences. The catalog number is T125689 and the CAS number is 1612239-54-9.