Inhibiteurs

PROTAC BTK Degrader-3 is a potent degrader of Bruton's tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells.

Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker.

Mitoquinone is a TPP-based, mitochondrially targeted antioxidant .

MCA17-1 exhibits superior bioactivity compared to the positive control, obeticholic acid (OCA), in the treatment of liver fibrosis.

Potent PROTAC ER Degrader-10 for cancer research; from patent WO2021133886, example 36.

Antitumor agent-109 (compound 6) is a dual-function inhibitor that targets hyaluronic acid and CD44, which are involved in tumor progression and invasion.

Heterocyclic compounds-pyridine,

Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.

Valiloxibic acid is a prodrug for GHB, a natural psychoactive neurotransmitter and weak GABAB agonist.

HT-2 Toxin, a deacetylated metabolite of T-2 toxin, impairs protein synthesis and hinders cell proliferation in plants.

Ceritinib D7 (LDK378 D7) is a deuterium-labeled Ceritinib. Ceritinib is an ATP-competitive inhibitor of ALK tyrosine kinase.

CF502 (STING agonist-23) is a non-nucleotide that activates STING pathway, boosts immune responses, and shows activity against SARS-CoV.

Phosal 50 PG is a co-solvent used as an emulsifier and stabilizer in the pharmaceutical and cosmetic industries.Phosal 50 PG is used as a dietary supplement.

Danoprevir sodium is an NS3/4A protease inhibitor used in the treatment of Hepatitis C

Elamipretide 2TFA (RX-31 2TFA) is a novel mitochondrion-targeted antioxidant.

Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.

p-Toluic Acid (4-Methylbenzoic acid) belongs to the class of organic compounds known as benzoic acids. 4-Methylbenzoic acid has been primarily detected in saliva. Within the cell, 4-methylbenzoic acid is primarily located in the cytoplasm.