Glucides et Glycoconjugués

<p>A custom synthesis of a complex carbohydrate. It is a synthetic, modified and fluorinated saccharide with a methylated monosaccharide.</p>

<p>Glycyl-sialyllacto-N-tetraose c is a custom synthesis of the carbohydrate polysaccharide glycyl-sialyllacto-N-tetraose. It is a complex carbohydrate that has been modified for use in biochemical research. Glycyl-sialyllacto-N-tetraose c contains four sugars, including erythrose and threose, and has been fluorinated at the C5 position. The modification of this carbohydrate was achieved through a click reaction. This product has been purified to be greater than 95% pure and is ready for use as an organic solvent or chemical reagent in laboratory experiments.</p>

<p>Synthetic building block for oligosaccharide synthesis</p>

<p>Glycyl-2'-fucosyllactose is a monosaccharide that is modified by glycosylation, methylation, and click modification. The fluorination of the saccharide leads to its increased water solubility and resistance to hydrolysis. Glycyl-2'-fucosyllactose is used in the synthesis of oligosaccharides for use as a scaffold for drug delivery and protein engineering.</p>

<p>GD1a ganglioside is one of the major gangliosides in neuronal and glial membranes. It has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD1a ganglioside interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GD1a ganglioside plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. GD1a ganglioside also interacts with botulinum neurotoxin (BoNT) and is crucial for its entry into cells (Kolter, 2012). The functional significance of ammonia in the brain is not fully understood see: (Modi, 1994).</p>

<p>Blood group antigen conjugated to spacer and biotin</p>

<p>Glucomannan oligosaccharides are modified polysaccharides of plant origin. They are not digested in the small intestine and are instead fermented by the large intestine to produce short-chain fatty acids. This is a novel approach to weight control. The modified monosaccharide backbone provides for a more complex carbohydrate than found in other dietary fibers, and this complex carbohydrate is resistant to digestion by mammalian enzymes. Glucomannan oligosaccharides can be used as a replacement for high-calorie sweeteners in many food applications and as a bulk laxative.</p>

<p>The structural analysis of chondroitin disaccharide di-0S sodium salt has been done by a bacterial enzyme, which is an enzyme that catalyzes the hydrolysis of glycosidic bonds. The reaction mechanism is spontaneous and the biochemical analysis indicates that the molecule is a glycosidic bond with hemiketal and hydration. The active site residues are found to be water molecule, which help in binding with the substrate to form a hemiketal. Biochemical analysis of this molecule reveals that it is an oligosaccharide with two sugar molecules linked by glycosidic bond.</p>

<p>Sialyl Lewis X ceramide is a monosaccharide that belongs to the pentasaccharide group. It is expressed in the cells of leukemia and erythrocytes, as well as other tissues. Sialyl Lewis X ceramide is a hybrid molecule that has a backbone consisting of four sugar molecules and an amino acid sequence, with hydroxyl groups on one end and an acetyl glucosamine on the other end. The molecule has a carbohydrate skeleton consisting of galactose, glucose, mannose, and sialic acid. Sialyl Lewis X ceramide also interacts with selectins to mediate leukocyte-endothelial interactions in inflammation.</p>

<p>Sucrose-6-phosphate sodium is a transcriptional regulator that belongs to the group of sugar phosphate ions. Sucrose-6-phosphate sodium regulates the transcription of genes involved in the synthesis of polysaccharides, such as sucrose and starch. This compound plays an important role in the metabolism of plants and has been shown to regulate hydrogen bond formation, photosynthetic activity, glycosidic bond formation, polymerase chain reactions, and regulatory sequences. The optimum pH for this compound is 7.0, with enzyme activities between pH 6.0 and 8.5. Sucrose-6-phosphate sodium also has been shown to regulate root formation and phosphorus pentoxide production in corynebacterium glutamicum.</p>

<p>Acarviosin is a chemical compound that is structurally related to the antimicrobial peptide Ac-LLL-Nal-OH. It is an antidiabetic agent that has been shown to be effective for the treatment of type 2 diabetes and associated cardiovascular risk factors. Acarviosin was originally isolated from a bacterial strain and has been chemically synthesized for use in the treatment of diabetes. Acarviosin inhibits both glycan synthesis and enzyme activities, leading to reduced levels of glucose in blood plasma. This drug also exhibits pharmacokinetic properties with a half-life of approximately 15 hours, which allows it to be taken once daily. Acarviosin can also be used as an analytical method for identifying disaccharides by cleaving them at the glycosidic bond, releasing monosaccharides as products.</p>

<p>Trehalulose is a sugar that is found in plants, animals, and fungi. It is a reaction product of glucose with the enzyme trehalase, which cleaves off two molecules of water to form one molecule of glucose and one molecule of trehalulose. Trehalulose has been shown to be an inhibitor of phosphofructokinase, an enzyme involved in glycolysis. This inhibition can be reversed by the addition of ATP or pyruvate kinase. Trehalulose also has been shown to inhibit the growth of cells by interfering with protein synthesis. Trehalulose may have biological functions including dietary uses as a replacement for sucrose or lactose due to its low calorie content and high level of sweetness.br&gt;br&gt; Trehalulose is structurally similar to sucrose because it has both a glucose part and a fructose part and it will react with hydrogen fluoride (HF) in dry weight reactions, forming trehalo-s</p>

<p>4-Methoxyphenyl 2-acetamido-3,6-di-O-acetyl-4-O-[2,4-di-O-(3,6,9)-triacetyldi-O-(3,4,6)-triacetyldiacetamido]-bDglucopyranoside (MPPA) is a modification of the natural oligosaccharide 3,6,-di-O-(2,4-di-O-(3,6,9)-triacetyldiacyl)-bDmannopyranosyl. MPPA is synthesized by methylation and glycosylation of glucose residues in the backbone of the natural oligosaccharide. The methylated glycosidic linkages are substituted for acetamido groups in order to confer water solubility to the molecule. MPPA has been shown to be an effective inhibitor of influenza virus replication in vitro.</p>

<p>Isolated from the products of the acid reversion of D-mannose</p>

<p>Pentasaccharide derived from chitin</p>

<p>Blood group H type II trisaccharide is a carbohydrate that is modified with a spacer-biotin conjugate. It can be used in the synthesis of oligosaccharides and saccharides. This product has been fluorinated, has high purity, and is custom synthesized to order. The product also has methylation, glycosylation, and click modification.</p>

<p>Heparin is a complex carbohydrate that has been modified by the addition of a sugar and a sulfate group. It is used in the treatment of thrombosis, deep vein thrombosis, pulmonary embolism, and other blood clots. Heparin disaccharide IV-S disodium salt (HDS) is an intravenous form of heparin that consists of sodium salts of two saccharides: heparin disaccharide and sodium disulfate. HDS has been shown to be more potent than unfractionated heparin in animal models, as well as being more effective in preventing clot formation in humans. This drug also exhibits less frequent side effects such as skin rash, itching, or hives.</p>

<p>This is a custom synthesis of a complex carbohydrate. The CAS number is not available and the polysaccharide has been modified. It has been glycosylated, methylated, and fluorinated. It is high purity and the sugar sequence is a custom synthesis.</p>

<p>This compound is a synthetic glycosylation reagent that is used for the modification of proteins and polysaccharides. It can be used to introduce various sugars and oligosaccharides to proteins, such as Methylation, Click modification, Polysaccharide, Fluorination, saccharide, Modification, sugar, Oligosaccharide. The compound has a CAS No. 946164-26-7 and is available for custom synthesis with high purity.</p>

<p>The Lewis A glycan is a complex carbohydrate that consists of a sulfated disaccharide and an oligosaccharide. The Lewis A glycan is a modification of the Lewis B glycan, which lacks the sulfate group. The saccharide component is a monosaccharide, and can be synthesized using custom synthesis or purchased from CAS No.</p>

<p>3-(b-D-Glucopyranosyl)-D-mannose is a sugar that is a component of the complex carbohydrate called glycosaminoglycan. It can be used in the synthesis of oligosaccharides and monosaccharides or as a modification to saccharides. 3-(b-D-Glucopyranosyl)-D-mannose is synthesized through Click modification with fluorination, glycosylation, and methylation. This sugar has CAS No. 27212-79-4 and molecular weight of 360.3 g/mol.</p>

<p>This mixture contains some of the sialylated oligosaccharides found in human milk.</p>

<p>GD2 oligosaccharide is the core trisaccharide structure of the ganglioside GD2 (sodium salt) (GalNAcβ1,4Galβ1,4Glc) with its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Biotin-labelled oligosaccharide domain of the monosialylated glycosphingolipid GM2 of a-series. The compound is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system. GM2 is also overexpressed in melanomas and other tumours of neuro-ecto origin. Moreover, the sugar moiety of this ganglioside is a receptor allowing viral infection of cells with reovirus and rotavirus.</p>

<p>4'-O-(a-D-Galactopyranosyl)-D-lactose is a synthetic and fluorinated glycoside that belongs to the class of oligosaccharides. It has a molecular weight of 474.07 Da and a chemical formula of C12H23NO8. This product is available in custom synthesis in order to meet the needs of customers. It also has been modified with methylation, monosaccharide, polysaccharide, saccharide, click modification, and complex carbohydrate modifications. This product is available at high purity with CAS No. 834-02-4 and can be ordered from our website.</p>

<p>Neu5GcAc[1Me,4789Ac]a(2-6)Gal[24Bz,3Bn]-b-MP is a custom synthesis of an oligosaccharide. This complex carbohydrate has a CAS No. and has been modified to include methylation, glycosylation, and click modification. The sugar is a high purity fluorinated synthetic saccharide with a glycosylation site at the reducing end of the chain.</p>

<p>Benzyl 4- O- b- D- glucuronyl-b- D- xylopyranoside is a synthetic derivative of benzyl 4- O- b- D- glucuronylxylose. It has been shown to be a good substrate for glycosylation, click modification and fluorination. This product has been custom synthesized for the synthesis of complex carbohydrate, which is an oligosaccharide. It is also used in methylation reactions.</p>

<p>Lewis A is a trisaccharide that has been found to be present in the glycan structures of spermatozoa. It has also been identified as a major component of the glycan structures on the surface of HL-60 cells. Lewis A is composed of three monosaccharides, galactose, fucose, and N-acetylgalactosamine, which are linked together with a beta (1→4) linkage. The hydroxyl group on the galactose molecule allows for steric interactions with neighboring sugar molecules through hydrogen bonding and van der Waals forces. The Lewis A trisaccharide is an important marker for identifying blood type O because it does not have any antigenic determinants that can cause an immune response.</p>

<p>Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.</p>

<p>1,5-α-L-Arabinotriose is a sugar that is found in the cell walls of plants. It is a trisaccharide composed of three L-arabinose units linked by α-(1→5) bonds. 1,5-α-L-Arabinotriose has been shown to be adsorbed on cellulose acetate and can be used to measure the molecular weight of the adsorbate. This sugar also undergoes optical rotations when it interacts with some dyes such as germanium tetrachloride. 1,5-α-L-Arabinotriose has many uses including: as a solute in chloride ion chromatography; as an absorbent in filtration experiments; and as a parameter for calculating thermodynamics for reactions involving hydrogen transfer.</p>

<p>4-Methoxyphenyl 4-O-(2,4,6-tri-O-acetyl-3-O-allyl-b-D-galactopyranosyl)-3-O-allyl-b-Dglucopyranoside is a synthetic sugar with a molecular weight of 532. This product can be used in the synthesis of oligosaccharides and monosaccharides. It is also used as an intermediate in glycosylation reactions. This product has not been assigned a CAS number yet.</p>

<p>Oligogalactosyllactose is a polysaccharide made from galactose and glucose. Oligogalactosyllactose has been shown to have an inhibitory effect on the growth of Staphylococcus aureus strains. Oligogalactosyllactose also has anti-inflammatory properties, which may be due to its ability to bind to free fatty acids and reduce the production of pro-inflammatory cytokines. This dietary ingredient is found in inulin, which is a type of carbohydrate that can be found in some vegetables. Oligogalactosyllactose is composed of short chains of sugar molecules, making it easier for the body to absorb. It is also more readily metabolized by bacteria in the gut than other types of carbohydrates like celluloses or starches.</p>

<p>Trehalose is a naturally occurring disaccharide found in many organisms. Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesised by cells in response to stress and helps retaining the cellular integrity under tough conditions. An important function of trehalose is to stabilise protein structures and to prevent proteins from their degradation. Researchers use trehalose for instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>Disaccharide is a carbohydrate with two simple sugars. It is soluble in water and has a density of 1.621 g/ml. Disaccharides are found in the tissues of many plants and animals, where they can be hydrolyzed by various enzymes to release monosaccharides. Disaccharides are also found in certain types of lichen and algae, where they are produced through photosynthesis. The most common disaccharides are sucrose, lactose, maltose, trehalose, and cellobiose. The simplest type of disaccharide is called a monosaccharide or sugar molecule. Monosaccarides have the same chemical formula but different physical forms that depend on their molecular mass (i.e., they may be a solid or liquid). Disaccharides can be classified as either sulfuric or organic solvent-soluble depending on whether they dissolve in sulfuric acid or an organic solvent such as ethanol or</p>

<p>LacDiNAc dimer ethylazide is a modified form of LacdiNAc that has been iodinated. It is synthesized by the reaction of two molecules of LacdiNAc with ethylazide. The product has an average molecular weight of 2,000 and is the most highly purified synthetic carbohydrate available. It can be used in a wide range of applications, including click chemistry, glycosylation reactions, and fluorination synthesis.</p>

<p>Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions</p>

<p>N-[2-Acetamido-2-deoxy-6-O-(a-L-fucopyranosyl)-D-glucopyranosyl]-L-asparagine is a custom synthesis methylated oligosaccharide with a molecular weight of 732.13 Da. It has been fluorinated, modified and saccharide methylated. N-[2-Acetamido-2-deoxy-6-O-(a-L-fucopyranosyl)-D-glucopyranosyl]-L asparagine is soluble in water and has a purity of &gt;98%. The chemical name for this compound is 2-[(5Z,6E)-5,6,7,8,9,10,11,12,13,14,15,16] -octadecahydro--[1H] -indeno[1',3':4',5]pyrrol</p>

<p>4-Methoxyphenyl 4-O-[2,6-di-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-4-O-benzylbDmannopranosyl]-3,6diObenzyl 2 -deoxy2 -phthalimidoBglucopyranoside is a carbohydrate that belongs to the group of oligosaccharides. It is a saccharide that consists of an acetate ester and an acetal linkage. This carbohydrate has been custom synthesized for use in click chemistry. 4MPP4ODABAGMBZ is a synthetic monosaccharide with a methylation and glycosylation modification.</p>

<p>Oligosaccharide domain of monosialylated glycosphingolipid GM1 with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.</p>

<p>Synthesized by the 4,6-O-benzylidene acetal-controlled method of Crich</p>

<p>Trifucosyl (1-2,1-2,1-3)-iso-lacto-N-octaose is a custom synthesis that is a complex carbohydrate. It is an oligosaccharide that contains three monosaccharides linked by alpha glycosidic bonds. This compound has been modified using methylation and glycosylation reactions. Trifucosyl (1-2,1-2,1-3)-iso-lacto-N-octaose has been fluorinated at the C6 position of the sugar ring to increase its solubility in water and enhance its stability in acid conditions. The product is a high purity synthetic compound.</p>

<p>2,2',2''-Triaminotriethylamine-bis(thiogalactopyranosyl acetamide) is a fluorinated sugar that can be used as a building block in glycosylation and oligosaccharide synthesis. It has been shown to be useful for the preparation of complex carbohydrates with desired properties such as high purity.</p>

<p>Glycyl-disialyllacto-N-tetraose is a complex carbohydrate that contains a glycosidic bond between two monosaccharides. It has the molecular formula C9H18O4N2O8 and CAS number 327977-92-3. This compound can be modified with methylation, glycosylation, or fluorination to increase solubility and stability. Glycyl-disialyllacto-N-tetraose is also known as Oligosaccharide, CAS No., Polysaccharide, Modification, saccharide, Methylation, Glycosylation, Click modification and Carbohydrate.</p>

<p>Used as enzyme substrates, analytical standards and for in vitro diagnostics</p>

<p>Starch breakdown product; sweetening agent; fermentable intermediate in brewing</p>

<p>Heparin is a glycosaminoglycan which is a complex carbohydrate that contains repeating disaccharide units of glucosamine and N-acetylglucosamine. Heparin has been shown to inhibit the activity of bacterial enzymes involved in fibrinolysis, such as plasminogen activator inhibitor 1 (PAI-1), and may act as an anticoagulant. Heparin is often used as an anticoagulant in patients with thrombotic disorders, including deep vein thrombosis, pulmonary embolism, or heart attack. Heparin also acts as a cofactor for the activation of clotting factors II (thrombin), VII, IX, X, XI and XII. In addition, it inhibits the activation of factor XIII by preventing its conversion from its inactive form into active factor XIIIa. The molecular weight of heparin is approximately 10 kilodaltons (kDa) and it has a molecular formula</p>

<p>4-O-(b-D-Mannopyranosyl)-D-glucose is a metabolite of D-mannose. It is a bacterial metabolite produced by Streptococcus pneumoniae that has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. 4-O-(b-D-Mannopyranosyl)-D-glucose inhibits bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifapentine also specifically binds to markers expressed at high levels in Mycobacter</p>

<p>Derived from pullulan using pullulanase</p>

<p>Mixed DP 25-50 Na galacturonans, (α-1,4 25-50 Na galacturonans) are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s). In recent studies, it has been shown that long oligogalacturonides (degree of polymerization (DP) from 25–50), help to induce plant defense signaling resulting in enhanced defenses to necrotrophic pathogens.</p>

<p>4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-4-O-levulinoyl-2-phthalimido-b-D-glucopyranosyl)-3-O-(4 methoxybenzyl)-2 deoxy 6 - O-(4 methoxybenzyl) - 2 phthalimido b D glucopyranoside is a complex carbohydrate that can be custom synthesized. It has been fluorinated. The modification of methyl groups on the saccharide moiety and its glycosylation make it a highly purified carbohydrate. This product has CAS No. 71181, Click modification, and Modification.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-maltosyl bromide is a fatty acid that is isolated from the fungus Penicillium notatum. It has been shown to have anti-cancer properties by inhibiting cell proliferation and inducing cancer cell death by apoptosis. The mechanism of action has been shown to be due to its ability to inhibit the phospholipid membrane synthesis and disrupt the interaction between lipids and proteins in the membrane. This compound also inhibits the growth of cancer cells by binding with the hydroxyl group on the surface of cancer cells. 2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-maltosyl bromide has been shown to inhibit muscle cell proliferation in vitro and in vivo. This drug can be used as an alternative for treatment for cancer or other diseases that are caused by muscle</p>

<p>Hyaluronic acid is a glycosaminoglycan found in many organs where it functions as a joint lubricant and shock absorber (Collins, 2006). It is obtained principally from synovial fluid, vitreous humor of the eye, umbilical tissue and cockscomb. The chemical structure of hyaluronic acid is a disaccharide repeat of β-1,3 glucuronic acid and β-1,4 N-acetyl glucosamine (Casu, 1990). Hyaluronic acid is a common ingredient in skin care products and is used as a dermal filler in cosmetic surgery.</p>

<p>Man-7 Glycan is a synthetic, 2-AB labelled fluorinated monosaccharide. It is an oligosaccharide that is synthesized by the glycosylation of mannose and N-acetylglucosamine. This product has been modified with fluorination, methylation, and click chemistry.</p>

<p>This compound is generally known as sucralfate and is a medication for the treatment of active duodenal ulcers. It is also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.  Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.</p>

<p>6-O-(b -D-Galactopyranosyl)-D-glucopyranose, also called allolactose, is a glucose disaccharide with β1-6 glycosidic link, similar to lactose (glucose β1-4 linked). Allolactose is an inducer of the lac operon in E. coli and many other enteric bacteria.</p>

<p>4-Methoxyphenyl 4-O-{3-O-[2,4-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido -bDglucopyranosyl)-3,6-di-ObenzylbDmannopyranosyl] -4,6-- Obenzylidene--2-- Olevulinoyl-- bDglucopyranosyl} -3,6-- diOBenzyl 2-- deoxy 2-- phthalimido bDglucopyranoside is an oligosaccharide with a sugar backbone. This compound has been synthesized by the glycosylation of 4 methoxyphenol and 3,4,6 tri O acetyl 2 deoxy 2 phthalimido b D glucopyranoside. The glycosidic bond was formed between C 1</p>

<p>N-Acetylneuraminyl-(a2-3)-D-galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosamine is a synthetic modified N-acetyllactosamine. It is a complex carbohydrate that is composed of an acetamido group, a galactose residue and a N-acetyle neuraminic acid residue. It has been used to study the effect of methylation on the interactions between carbohydrate chains and enzymes. This compound can be used in the synthesis of oligosaccharides or polysaccharides.</p>

<p>Intermediate degradation product of lyso-GM3</p>

<p>4-Methoxyphenyl 4-O-{4-O-[[2-O-Ac-3-O-[2,4-di-O-(3,4,6-tri-O-Ac-2'-deoxy-[2,3]-Bn] -b'-DGlc]-3,6'-di-'O-[(3',4',6'-tri-'O-'Ac)-2'-deoxy-[2'', 3''] -Bn]-a'-DMan]] -b'-DMan]] -3,6'-di-'O-[(3',4',6'--tri-'O-'Ac)-2' ',' 3'' ',' 6'' '--Deoxy-[2' ', 3' ',' 4'' ', 6'' '--Bn] -a'-DMan]] -b' DMan]] -6'-Octaacetate], is a complex carbohydrate that has been modified with a methyl</p>

<p>Produced from various chondroitin sulfates by the action of chondroitinases ABC, AC-1 and C.</p>

<p>2-Acetamido-4-O-{2-acetamido-4-O-[3-O-[2-O-(2-acetamido-2,6-dideoxygalactopyranosyl)-a,D]-mannopyranosyl]-6 -O-[2 - O-(2 - acetamido - 2, 6 - dideoxygalactopyranosyl) - a, D] - mannopyranosyl} - 2 - deoxy - b, D]glucopyranosyl} - 2 - deoxyglucose is a synthetic carbohydrate that belongs to the group of oligosaccharides. It is a complex carbohydrate consisting of six glucose molecules linked by alpha (1→4) glycosidic bonds. The chemical name for this molecule is Custom synthesis and it has CAS No. 91471-04-8. This product can be modified through methylation, glycos</p>

<p>4-O-(2-Acetamido-2-deoxy-[UL-13C6]glucopyranosyl)-D-ribitol is a custom synthesis of an oligosaccharide, monosaccharide, and polysaccharide. It is a high purity and CAS No. custom synthesis with a high degree of modification. This product has been synthesized by methylation and glycosylation for use in the study of the structure and function of complex carbohydrates. The fluorination was done to the saccharide to give it the desired properties for use in various applications.</p>

<p>Please enquire for more information about 3'-Sialyl Lewis X including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 3,6-di-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a glycosylation product of the sugar, mannose. It can be used in the synthesis of oligosaccharides and polysaccharides with modifications such as fluorination and methylation. Methyl 3,6-di-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is also known by its CAS number, which is 57424-92-5.</p>

<p>Heparin is a linear sulphated polysaccharide comprising contiguous disaccharide units of a uronic acid and a derivative of 2-amino-2-deoxy-D-glucose. The heparin tetrasaccharide can be obtained from the degradation of heparin with the lyase enzymes isolated from Flavobacterium heparinum, which yields oligosaccharides terminated at the non-reducing end by the unsaturated unit, 4-deoxy-α-L-threo-hex-4-enopyranosyl uronic acid or its 2-0-sulphated derivative. The major product following lyase degradation is the trisulphated derivative DUA-2S + GlcNS-6S (unsaturated disaccharide). Other oligosaccharides such as the tetrasaccharide, illustrated below, can be produced by the lytic degradation of heparin (Moffat, 1991).</p>

<p>Key synthetic precursor for the synthesis of lacto-oligosaccharides</p>

<p>Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant</p>

<p>Nigerose is a chemical compound that belongs to the group of oligosaccharides. It is a glycan with a basic structure and has inhibitory properties. Nigerose is an important intermediate in the synthesis of high-mannose-type oligosaccharides, which are used as vaccines against infectious diseases. Nigerose has been shown to be an inhibitor of glycosyltransferases and can be used for wastewater treatment. This compound reacts with water to produce hydrogen gas, which can be harnessed for energy production. Nigerose also reacts with base solution in a titration calorimetry experiment to produce heat, indicating that it has a basic structure.</p>

<p>High mannose oligosaccharide found in urine of mannosidosis patients</p>

<p>Non-reducing storage and transport sugar in woody plants; used as a sweetener</p>

<p>Lipopolysaccharide (LPS) is a molecule that is produced by Porphyromonas gingivalis. This molecule is also found in the outer membranes of Gram-negative bacteria and has been shown to have many effects on animal tissues. LPS activates HIF-1α, which leads to the production of inflammatory cytokines such as necrosis factor (TNF), and interferon regulatory factors (IRFs). These molecules signal for the production of more LPS. LPS also causes tissue growth and development by activating growth factors such as insulin-like growth factor 1. LPS also activates immune cells through signaling with chemokine receptors, promoting inflammation.</p>

<p>Raffinose-sp-biotin is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. It is available in CAS No. and has the molecular formula C6H14O6. Raffinose-sp-biotin is a polysaccharide with a complex carbohydrate structure.</p>

<p>The ‘tallowate’ esters are probably the best known derivatives of sucrose and many attempts have been made to commercialise them in order to exploit their excellent surfactant functionalities.  The most functional products are the mono- and diesters of the tallow acids (stearic, palmitic, oleic) with hydrophile-lipophile balance (HLB) values that lend themselves to surfactant applications in foods and cosmetics.  They also have other uses, for example in coating fruits with a semipermeable membrane that acts as a preservative.  Manufacturing economics have prevented these products from mass production and they remain in niche applications.</p>

<p>Lacto-N-difucohexaose IV is a pentasaccharide with a lacto-n-difucohexaose backbone that has been shown to have inhibitory activities against human red blood cells. This pentasaccharide is a glycosaminoglycan, which is a type of carbohydrate that consists of an oligosaccharide and protein. Lacto-N-difucohexaose IV specifically binds to the antigen on the surface of human red blood cells, inhibiting their proliferation. The pentasaccharide is also known as Hansson's hapten or Hapten IV. The pentasaccharides are found in group O blood and are not found in groups A, B, or AB.</p>

<p>Chitobiose-6'-phosphate is a carbohydrate that is used in the synthesis of oligosaccharides. It can be modified to produce different types of saccharides, such as methylation, saccharide click modification, and modification. Chitobiose-6'-phosphate is available in high purity and offers a custom synthesis service for specific requirements.</p>

<p>Monosialyllacto-N-neohexaose is a postulated sugar that has been suggested to be a membrane potential stabilizer. It has been shown to have a linear response in analytical methods, such as mitochondrial membrane potential and glycosidic bond. Monosialyllacto-N-neohexaose has also been investigated for use in diabetic patients because it may help to improve the membrane potential of cells. This sugar has also been studied for use in colostrum and infant formula due to its ability to stimulate the production of TNF-α, which is important for immune system development.</p>

<p>Carbon source for E. coli; inhibitor of lysozymes</p>

<p>2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-a-D-galactopyranosyl-1-O-[4-(aminomethyl)benzoyl]-L-serine (2ADOGB) is a side chain of the amino acid L -serine. It has been shown to have antihypertensive, vasodilatory, and diuretic properties in mice. 2ADOGB is converted to an erythroimidazole derivative by aminomethylation and then binds to DNA as a tautomer. This binding inhibits transcription of genes that encode enzymes responsible for synthesizing prostaglandins, thereby reducing inflammation and pain.</p>

<p>2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl threonine is a carbohydrate antigen that is expressed on the surface of cancer cells. The antigen has been shown to be an efficient target for antibody conjugates and electrochemical impedance spectroscopy. 2A6T is a synthetic derivative of the natural sugar N-acetylgalactosamine and it can be synthesized by modifying the natural pathway in order to produce more of this antigen. This compound has been shown to be an excellent candidate for targeting prostate carcinoma, which is one of the most common cancers in men.</p>

<p>N-Acyl-neuraminyl lactoses are a class of modified N-glycosides that can be synthesized from monosaccharides, such as glucose and galactose. The modification of the sugar moiety with a fatty acid has been shown to confer resistance to hydrolysis by bacterial enzymes. This is due to the fact that esterases cannot cleave the bond between the fatty acid and the sugar, which prevents hydrolysis.<br>The synthesis of these compounds is achieved through an oxidative process using sodium hypochlorite in methanol solution. The reaction starts with oxidation of glycerol followed by substitution of the hydroxyl group on glycerol with a fatty acid chloride. The final product is then purified by liquid chromatography.</p>

<p>a-Sophorose monohydrate is a water soluble β 1-2’ diglucoside which can be used to induce cellulase production from fungi. The industrial production of cellulase is of importance due to its application in the degradation of lignocellulosic biomass to biofuels. a-Sophorose monohydrate is also a useful chemical building block for carbohydrate synthesis.</p>

<p>4-Methoxyphenyl 4-O-(4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,6'-dideoxygalactopyranoside is a modification of the natural carbohydrate galactose. The sugar moiety has been methylated and glycosylated with a levulinate ester and then fluorinated. This compound is highly pure and can be synthesized on custom order.</p>

<p>Biotin impurity C 2HCl is an analytical standard impurity in drug product. It is a bivalent form of biotin, which is a natural amide with the chemical formula C 20 H 27 ClN 2 O 4 S. It has been synthesized and characterized as a custom synthesis. The purity of this compound meets the requirements of pharmacopoeia.</p>

<p>Core human milk oligosaccharide</p>

<p>1,6-Anhydro-2-azido-3-O-benzoyl-4-O-(2,3-di-O-benzyl-6-methyl-b-Dglucopyranosyl)-bDglucopyranose is a custom synthesis that is an oligosaccharide with a molecular weight of 672.1 Da. It is a complex carbohydrate that has been modified to include saccharides and sugars, with the addition of methylation and glycosylation. This molecule has been fluorinated for the purpose of synthesizing a synthetic molecule.</p>

<p>CO2-philic compound with uses in pharmaceuticals and CO2-based processes</p>

<p>Chitotriose undecaacetate is a synthetic substrate that is used in transfecting experiments. It has high sensitivity and can be used to introduce nucleic acid into cells. Chitotriose undecaacetate is used as a synthetic fluorometric assay for the determination of chitinase activity in vitro or as a substrate for cell-free synthesis of nucleic acids. It has been shown to possess moieties that are sensitive to hydrogen chloride and chloride ions, making it an effective probe for the determination of these ions. Chitotriose undecaacetate also reacts with sephadex G-200, which makes it useful for separating DNA fragments by electrophoresis.</p>

<p>Dextran 2000 is a high molecular weight biocompatible polymer with transport properties. It is used in a variety of medical applications, such as red blood cell transfusions and the prevention of post-surgical adhesions. Dextran 2000 has been shown to be a safe and effective means of preventing hemolysis during red blood cell transfusion. This agent binds to amine groups on the surface of erythrocytes, which prevents complement activation and subsequent lysis. Additionally, dextran 2000 has been shown to exhibit low cytotoxicity against neuronal cells in vitro.</p>

<p>4-Aminophenyl 6-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is a custom synthesized carbohydrate that belongs to the group of oligosaccharides. It is a saccharide with a mannose, glucose, and mannose backbone structure. This compound has been modified by methylation at the C4 position, glycosylation at the C3 position, and fluorination at the C6 position. The 4-aminophenyl 6-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is available in high purity and can be used for research purposes.</p>

<p>6'-N-Glycolylneuraminyl-D-lactose sodium salt is a custom synthesis that provides high purity and custom synthesis. It is a complex carbohydrate with a CAS number of 24932-91-0 and an Oligosaccharide, Monosaccharide, saccharide Carbohydrate. This product is Fluorination, Glycosylation, Synthetic, Methylation, Modification.</p>

<p>Isolated from ivory-nut mannan, Picea glauca and Pinus strobus glucomannans</p>

<p>Disialyllacto-N-tetraose is a medicinal compound that has shown promising anticancer properties. It is an analog of a human urinary glycoprotein and has been found to induce apoptosis in cancer cells. Disialyllacto-N-tetraose acts as a tumor inhibitor by blocking the activity of certain protein kinases, which are enzymes that play a role in cell growth and division. This compound has been studied extensively in Chinese medicine and has shown potential as an effective anticancer agent. Its unique structure and mechanism of action make it a promising candidate for further research into cancer treatment.</p>

<p>2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio-D-ribofuranose is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide with CAS No. and a Polysaccharide that has been modified by Methylation and Glycosylation. It is also a Modification of saccharide, which is a Carbohydrate that contains the sugar, glucose. The purity of 2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio--D--ribofuranose is high and it has been Fluorinated for Synthetic purposes.</p>

<p>α 1,4-glucodecasaccharide derived from starch by hydrolysis and chromatography</p>

<p>Gal-b-1-3-GalNAc-b-1-4-Gal-b-1-4-Glc is a polysaccharide that is an important component of the outer membrane of Gram negative bacteria. It has been synthesized and modified with methylation, saccharide, Click modification, and glycosylation. The oligosaccharide has a high purity and is synthesized by custom synthesis. GalNAc is purified by HPLC and fluorinated to achieve complex carbohydrate.</p>

<p>Lactobionic acid is produced by oxidation of lactose. It is widely used in the food and in pharmaceutical field, due to its excellent biocompatibility, biodegradability, nontoxicity, chelating, amphiphilic and antioxidant properties.  Lactobionic acid is produced as a white solid powder, freely soluble in water and slightly soluble in anhydrous ethanol and methanol.</p>