Glucides et Glycoconjugués

<p>1-S-Acetyl-2-acetamido-3-O-(2,3,4,6-tetra-O-benzoyl-b-D-galactopyranosyl)-2-deoxy--D thiogalactopyranose is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide that has been modified with methylation and glycosylation. This product is available in high purity and has been fluorinated for synthetic purposes.</p>

<p>Neutral hexasasaccharide naturally present in human breast milk</p>

<p>b1-4 penta mannuronosaccharide-from alginate by enzyme or acid hydrolysis</p>

<p>Neocarrabiose is a low-energy, hydrogen-bonded sugar that has an optimum concentration of 0.5 M. It is found in the basic structure of oligosaccharides and belongs to group p2. Structural analysis has revealed that Neocarrabiose has a denaturation temperature of 98 °C. Clinical studies have shown that Neocarrabiose may be effective in treating influenza virus, although it is not currently approved for this use. Neocarrabiose can be used as a molecule to form intramolecular hydrogen bonds in organic synthesis and magnetic resonance spectroscopy.</p>

<p>Man-9 N-glycan is a glycoprotein that is found on the surface of many viruses. It has an oligosaccharide structure, which consists of a mannose and a glucose molecule linked by an alpha-1,3-glycosidic bond. The Man-9 N-glycan can be found in human serum and is involved in lectin binding to cells. It also has antiviral activity and may be used as a model system for studying glycosidic bonds. This glycan can be broken down into smaller components by methyl glycosides or titration calorimetry, which is a technique for determining the molecular weight of substances. The Man-9 N-Glycan binds to toll-like receptor 2 (TLR2) on the surface of human cells, which activates an antibody response.</p>

<p>Neutral tetrasaccharide naturally present in human breast milk</p>

<p>Pentagalacturonic acid (α-1,4 galacturonopentaose) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate and characterize endo- and exopolygalacturonase(s) and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, tetra-galacturonate, and penta-galacturonate oligosaccharides, restores development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>Di-guluronic acid sodium (DGA) is a custom synthesis of an oligosaccharide that has been modified with methylation and glycosylation. It can be used in the production of Oligosaccharides, which are complex carbohydrates. DGA is synthesized by a process called Click chemistry, which includes a modification called fluorination. DGA is also a polysaccharide and a sugar, as well as being high purity and having high molecular weight.</p>

<p>NGA1F N-Glycan is a custom synthesis, modification, fluorination, methylation, monosaccharide, synthetic glycan with a CAS No. that has been modified by the click chemistry reaction. It is an oligosaccharide that is saccharide and polysaccharide that has been glycosylated with sugar and carbohydrate.</p>

<p>Cellobiitol is produced by the borohydride reduction of cellobiose.  Few publications discuss the chemistry of cellobiitol but applications in the food and pharmaceutical industries have been published.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agaroheptaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.</p>

<p>4-Methoxyphenyl 4-O-(4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,4,6-(1',4'-dioxan)-tris(2,3,5',6'-tetraethoxy)phenol</p>

<p>Benzyl 4-O-b-D-galactopyranosyl-b-D-xylopyranoside is a glycoside that is used in the synthesis of antibiotics. It can be found in the leaves of "Ajania cordata" and "Chenopodium ambrosioides".</p>

<p>Triisopropylsilyl 2-azido-3-O-(2,3,4,6-tetra-O-benzoyl-b-D-galactopyranosyl)-4,6-O-benzylidene-2-deoxy--aDthiogalactopyranoside is an azido glycoside that can be used in the synthesis of oligosaccharides. It has been shown to be a potent inhibitor of bacterial growth. This compound is synthesized by reacting 2-(trimethylsilyl)ethanol with 3-[(2,3,4,6-tetraacetyl bDgalactopyranosyl)oxy]propionic acid and sodium azide in the presence of triethylamine. The reaction produces a mixture of products which are purified by chromatography. This product is then reacted with benzaldehyde to produce the desired product.</p>

<p>Methyl 2-O-(a-D-galactopyranosyl)-b-D-galactopyranoside is a custom synthesis that is fluorinated at the 2 position. It is an oligosaccharide, polysaccharide, and carbohydrate. The product has been modified with the Click modification and has high purity. It is also a monosaccharide sugar or synthetic sugar. Methyl 2-O-(a-D-galactopyranosyl)-b-D-galactopyranoside can be used in complex carbohydrates and fluorination reactions.</p>

<p>6-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is a fluorinated carbohydrate that belongs to the group of saccharides. It is a monosaccharide and can be custom synthesized for specific purposes. This product has been modified with click chemistry, methylation, and glycosylation. 6-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is soluble in water and has high purity.</p>

<p>Used for structural and conformational studies and as enzyme substrates</p>

<p>3'-Sialyllactose-sp-biotin is a monosaccharide that is modified with fluorine. It has been used in the synthesis of glycosylated proteins and peptides. 3'-Sialyllactose-sp-biotin is also used to modify glycoproteins, which are proteins that contain carbohydrate chains. The modification with fluorine makes this product ideal for use in the synthesis of glycosylated proteins and peptides.</p>

<p>Used as a sugar replacer in sugar-free confectionery and beverages</p>

<p>Non-reducing sucrose analog containing glucose and fructose</p>

<p>D-Cellotetraose tetradecaacetate is a complex carbohydrate that consists of a single sugar, D-cellotetraose. It is made up of four glucose molecules attached to each other by glycosidic bonds. The modification of this carbohydrate can be done by methylation and glycosylation. The synthesis of this molecule can be custom-made, as it is not found in nature. This product is high purity and has a CAS number: 83058-25-7.</p>

<p>Human milk oligosaccharide; binds cholera toxin TcdA</p>

<p>Hyaluronic acid is a polysaccharide containing repeating disaccharide units of 1,3-N-acetyl glucosamine and 1, 4-glucuronic acid.  This tetrasaccharide and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).</p>

<p>Cellotriose is a bifunctional sugar that can be chemically converted to cellobiose and D-cellopentaose. Cellotriose is a component of cellulose, which is the most abundant biopolymer on Earth. Cellotriose is a source of chitin, which is a major component of the exoskeleton of insects and crustaceans. The molecule has been observed using atomic force microscopy to have an amphiphilic nature, in that it has both hydrophobic and hydrophilic regions. Cellotriose has been synthesized in the laboratory for use as an artificial sweetener, but it does not taste as good as sucrose because it lacks the sweetness profile. When heated, cellotriose undergoes a color change from yellow to blue-green due to its ability to form hydrogen bonds with oxygen molecules. This property can be used as a colorimetric test for cellulase activity in solutions.</p>

<p>D-Celloheptaose is a modified glycosylated oligosaccharide. It is synthesized by the methylation of D-cellotriose with 3-aminopropyl-trimethoxysilane and the subsequent reaction with bromoethanol. The product is purified by fractional crystallization from methanol to give a white crystalline solid. This product has CAS No. 52646-27-2 and is soluble in methanol, ethanol, water, acetone and chloroform.</p>

<p>Lewis A tetrasaccharide is a glycosylated oligosaccharide with the following chemical structure: The Lewis A tetrasaccharide is a carbohydrate that has been modified with fluorination and methylation. This modification has been shown to increase its stability in aqueous environments. The Lewis A tetrasaccharide may be used as a synthetic monosaccharide for custom synthesis. It is also used as an intermediate for the synthesis of glycosylated oligosacscharsides.</p>

<p>N-Acetyl-D-lactosamine (LacNAc) is a natural structural element in a variety of glycoconjugates, found in milk, urine, meconium and glyciproteins. It’s a substrate for galactosidases, fucosyltransferases, and sialyltransferases. This LacNAc is also useful as a lectin inhibitory sugar and for characterizing lectins.</p>

<p>Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Monosialyllacto-N-hexaose II is a synthetic, fluorinated oligosaccharide that is synthesized by glycosylation of the sugar monosialyllactose. Monosialyllacto-N-hexaose II has a molecular weight of 514.5 Da and is soluble in water. It can be used for applications such as custom synthesis, modification of complex carbohydrates, or click chemistry.</p>

<p>4-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)ribitol is a disaccharide that is antigenic and has been shown to elicit an antibody response in rabbits. The carbohydrate is a determinant for the staphylococcus group A antigen and is an epitope for the S. aureus group D antigen. 4-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)ribitol also shows inhibitory activity against bacterial growth, including Staphylococcus aureus and Staphylococcus.</p>

<p>Heparin derived dp26 saccharide ammonium salt (HDA) is a glycosylation product of heparin. It is a complex carbohydrate polymer with a molecular weight of over 10,000 Da and consists of repeating disaccharides. The first sugar in the repeating disaccharide is N-acetyl-D-glucosamine, which is then methylated on the 6 position. HDA has been modified by fluorination to give it improved stability and prolonged half life. This product has been custom synthesized for use in biotechnology research and has high purity.</p>

<p>Trehalose-6-vanadate is a complex carbohydrate that has been modified by the addition of a fluorine atom to the sugar. It is synthesized from the sugar trehalose and vanadium pentoxide in a one-step reaction. Trehalose-6-vanadate can be used as a methylation reagent for saccharides, polysaccharides, oligosaccharides, and other carbohydrates. It can also be used in click chemistry, modification of proteins with carbohydrates, glycosylation reactions, and as a synthetic sugar. Trehalose-6-vanadate is highly pure and stable in solution.</p>

<p>Maltohexaose is a polysaccharide formed by 6 units of glucose and can be metabolised inside the cell to a substrate-based inhibitor of fucosyltransferases. It can also be converted to GDP-2-deoxy-2-fluoro-L-fucose, a competitive inhibitor of α-1,3-fucosyltransferase. Matohexaose is used as acceptor for measuring the activity of 4-Alpha-Glucanotransferase.</p>

<p>4'-O-(2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-galactopyanosyl) -b-D-lactose is a modified saccharide that belongs to the group of polysaccharides. It has a CAS number and can be custom synthesized by our company. This product is classified as a carbohydrate, sugar, or synthetic. It can be used in click modification, modification, or glycosylation reactions. 4'-O-(2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b -D -galactopyanosyl) -b -D -lactose is also fluorinated with trifluoromethanesulfonic acid and can be used for complex carbohydrate synthesis.</p>

<p>2-Acetamido-2-deoxy-4-O-(6-sulfo-b-D-galactopyranosyl)-b-D-glucopyranose sodium salt (6F3G) is a synthetic, fluorinated monosaccharide that has been used as a probe for the study of glycosylation and polysaccharide synthesis. 6F3G has been shown to be an effective inhibitor of the enzyme D-glycerate kinase, which catalyzes the conversion of D-glycerate to phosphoenolpyruvate. This inhibition leads to a decrease in the formation of ATP and NADH, which provides evidence that 6F3G binds to the active site of this enzyme.</p>

<p>Heparin sulfate NS-oligosaccharide NS is a high purity, custom synthesis, sugar-based heparin. Heparin sulfate NS-oligosaccharide NS is designed for use in glycosylation reactions and provides the opportunity to introduce a variety of functional groups including Click modification, fluorination, methylation, and glycosylation. This product contains no animal derived ingredients. Heparin sulfate NS-oligosaccharide NS can be used in a range of applications such as pharmaceuticals, agrochemicals, and food additives.</p>

<p>Heparin disaccharide IV-A, sodium (HDS) is a complex carbohydrate. It is an oligosaccharide that consists of a number of sugar molecules linked together to form a polysaccharide. HDS can be modified by methylation and glycosylation as well as fluorination and click modification. HDS has high purity and is synthetic.</p>

<p>NA4 Glycan, 2-AB labelled is a synthetic glycoconjugate. It is a glycosylation of an oligosaccharide and an amino acid residue with the modification of fluorination. NA4 Glycan, 2-AB labelled can be used for research purposes in methylation and Click chemistry. This product also has CAS No., which means it is custom synthesized to order. The purity of this product is high and it is synthetically produced, making it ideal for research purposes.</p>

<p>Blood group antigen derivative for biochemical research</p>

<p>Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.   Purity typically above 60%.  Contains other oligosaccharide fragments.  For a typical IC trace see datasheet section</p>

<p>Mixed DP 10-15 Na galacturonans (α-1,4 10-15 Na galacturonans) are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s). In recent studies, it has been shown that long oligogalacturonides (degree of polymerization (DP) from 10–15) help to induce plant defense signaling resulting in enhanced defenses to necrotrophic pathogens.</p>

<p>Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. It is used by mouth for constipation and either by mouth or in the rectum for hepatic encephalopathy. It generally begins working after 8-12 hours, but may take up to 2 days to improve constipation.</p>

<p>3'-Sulfated Lewis A sodium salt is a synthetic oligosaccharide that is used as an antigen for the diagnosis of pancreatic cancer. It is conjugated to a monoclonal antibody and binds to the Lewis A epitope on the surface of cells. 3'-Sulfated Lewis A sodium salt has been shown to be useful in bladder cancer, where it can be used as a marker for tumorigenicity. It has also been shown to stimulate selectins and increase sugar residues on cell surfaces, which may lead to increased tumor growth.</p>

<p>Non-cytotoxic; biocompatible; used for targeted drug deliveryDegree of polymerisation is greater then 400.Water solubility approx 1mg/ml</p>

<p>Synthetic building block for oligosaccharide synthesis</p>

<p>GM1 pentasaccharide biotin (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue and biotin linked β to position 1 on the reducing glucose moiety (Ledeen, 2009). The parent ganglioside GM1 is abundant in all mammalian brains, where it covers 10%-20% of the total ganglioside mixture. It is found in epithelial membranes and is a key element for bacterial toxicity and viral infection as it is the intestinal receptor for cholera toxin the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. GM1 ganglioside functions as a neurotrophic and neuroprotective compound and has been used therapeutically for diabetic and peripheral neuropathies. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>Produced from starch by transglycosylation-15 a-(1,4) linked glucose residues</p>

<p>Sucrose acetoisobutyrate (SAIB) is an emulsifier and is compatible with a wide variety of polymers, resins, plasticisers, oils and waxes - where it is used in surface coatings. Food applications have been developed for this compound and it has an E number (E444). It is recognized as a safe food additive in cocktail mixers, beer, malt beverages, or wine coolers and is a potential replacement for brominated vegetable oil.</p>

<p>Substrate for fucosidase; used in infant formula; improves health in infants</p>

<p>Beta-Cyclodextrin is a cyclic oligosaccharide with 7 D-glucose residues which are alpha-1,4-linked. beta-cyclodextrin is used in the food industry to encapsulate flavours and fragrances. Beta-cyclodextrin can increase the water solubility of compounds, such as curcumin; further, the cyclodextrin-curcumin complex also allows for a controlled, sustainable release in a wound healing study.</p>

<p>Lewis X tetrasaccharide (LX4) is a glycan that is found on the surface of human cells. It is an important diagnostic marker for microbial infections and has been shown to be present on the surfaces of both normal skin cells and malignant cells. The presence of LX4 can be detected using a monoclonal antibody in vitro. This glycan can also be used as a model system to study ischemia–reperfusion injury, since it has been shown to be sensitive to oxidative changes caused by reactive oxygen species generated during reperfusion. Studies have also shown that LX4 binds to enzymes such as malonic acid oxydoreductase, which are involved in the metabolism of lysine, arginine, and proline.</p>

<p>a1-3-Galactobiose-biotin is a synthetic, fluorinated oligosaccharide that has been modified with 3 biotin molecules. It is synthesized by the glycosylation of 1,3-galactobiose and is used as an intermediate in the synthesis of carbohydrates. The sugar moiety can be modified with different chemical groups and reactions such as methylation or click modification to change its properties.</p>

<p>Produced from starch; white hygroscopic spray-dried powder; easily digestible</p>

<p>This is a custom synthesis of 2-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-L-fucopyranose, which is an oligosaccharide that has been modified by methylation and glycosylation. This product is a white solid with a molecular weight of 671.87 and a melting point of 137°C. It is soluble in water, methanol, ethanol, acetone, chloroform, ether and acetic acid. The purity of this product is more than 99%.</p>

<p>2-O-(2-O-(a-D-Mannopyranosyl)-a-D-mannopyranosyl)-a-D-mannopyranose is an oligosaccharide that is synthesized by the glycosylation of a D-mannose with 2,3,4,6-tetra‑O‑benzoyl‑beta‑D‑glucuronic acid. This product is available in custom synthesis and can be modified to order. It has been shown to be highly pure and can be used for a variety of applications including glycosylation reactions, methylations, fluorinations, click modifications, and complex carbohydrate studies.</p>

<p>Obtained by the partial acetolysis of lambda-carrageenan</p>

<p>Component of glycoproteins and glycolipids expressed in antigens and receptors of proteins, bacteria and viruses. Found in the free form in human biofluids, including urine and milk - preventing adhesion of bacteria to urinary epithelium and inhibiting enteric pathogens respectively. An efficient inhibitor of neutrophil-activating protein of H.pylori (HPNAP)-mediated neutrophil activation.</p>

<p>6-O-Sulfated Lewis X is a complex carbohydrate that contains a 6-sulfated Lewis X monosaccharide. It has been synthesized to have a high purity and stability. 6-O-Sulfated Lewis X is soluble in water and can be used as a synthetic building block for the synthesis of saccharides, polysaccharides, and oligosaccharides. The compound has been modified to have fluorination at the C6 position.</p>

<p>The conformation of the 2-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-βDglucopyranosyl)-βDglucopyranosyl]oxy]ethyl]carbamic acid phenylmethyl ester molecule has been studied by X-ray crystallography. The molecule adopts a chair conformation with the two acetyl groups occupying equatorial positions. The molecule is planar with an angle of 110° between the NH and CO axes. The calculated electron diffraction pattern was in good agreement with the experimental data. The analysis yielded a set of independent amplitudes for each reflection that were analysed to give structure constants and electron distributions.</p>

<p>Occurs by epimerisation of maltose and transglucosylation</p>

<p>Competitive inhibitor of β-glucosidase from Streptomyces sp. and Paenibacillus polymyxa, occupying enzyme’s aglycone-binding site.  The compound is also a potent inducer of cellulase and other lignin-degrading enzymes in Schizophyllum commune.</p>

<p>A2F N-Glycan is an oligosaccharide that is found in the human body. It is a glycan that has been shown to be involved in a number of biological processes, including effector functions, site specific recognition, diagnosis, and biopharmaceutical production. A2F N-glycan has also been shown to have potential as a biomarker for autoimmune diseases and cancer. The A2F N-glycan profile may differ between patients with different cancers or autoimmune disorders. This difference in the A2F N-glycan profile may contribute to the development of personalized medicine by helping to diagnose these conditions and predict their prognosis.</p>

<p>Glycyl-lacto-N-fucopentaose VI is a polysaccharide that is synthesized by the enzymatic activity of glycosylase, methylase, and fluorinase. It can be modified with click chemistry to introduce a fluorine atom at the C4 position of the glucose molecule. This modification can be used for the synthesis of oligosaccharides. Glycyl-lacto-N-fucopentaose VI has CAS number 108897-96-5 and is available in high purity and custom synthesis.</p>

<p>GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP is a synthetic glycoconjugate that is a glycosylated complex carbohydrate. It has been modified by Click chemistry and fluorination, and contains the monosaccharides galactose, galactosamine, glucose, and glucuronic acid. GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP is used as a substrate for enzyme assays to study the activity of glycosyltransferases such as galactosyltransferase. This product can be used for research purposes in immunology, molecular biology, biochemistry and other fields.</p>

<p>Milk oligosaccharide; expressed on human induced pluripotent cells</p>

<p>GA2-ganglioside is a ganglioside that is found in the membranes of cells. GA2-Ganglioside has been shown to inhibit the growth of tumors by binding to macrophages and T cells, which are two types of white blood cells. It has also been shown that GA2-Ganglioside can be used as a target for an antibody response against human HL-60 tumor cells. The antibody response induces cell lysis and reduces the size of the tumor. GA2-Ganglioside has also been shown to have anti-inflammatory properties, which may be due to its ability to bind to α subunits on bowel disease and infectious diseases, such as murine sarcoma virus, causing an antibody response that causes cell lysis and prevents replication of these viruses.</p>

<p>3'-Sulfated Lewis X sodium salt is a synthetic carbohydrate with a sulfate group on the 3' position of the sugar. It is a selective blocker of E-selectin, a type of selectin that plays an important role in inflammation and tissue injury. The binding site for 3'-sulfated Lewis X sodium salt is the cavity at the end of the selectin molecule, which has a hydrophobic region. This cavity can be blocked by hydrophobic moieties such as sulfates, fatty acids, or steroids. 3'-Sulfated Lewis X sodium salt has been shown to be effective in treating inflammatory conditions such as asthma and arthritis.</p>

<p>A short chain isomer of inulin</p>

<p>3'-Sialyllacto-N-neotetraose sodium is a synthetic, fluorinated oligosaccharide with a sialic acid side chain. This compound has been shown to be an inhibitor of lacto-N-neotetraose synthesis in the human gut. It is also used as a raw material for the synthesis of various complex carbohydrates and as a click modification reagent for saccharides and polysaccharides. 3'-Sialyllacto-N-neotetraose sodium can be modified at its methyl group or sugar moiety to produce desired products.</p>

<p>This comound is generally known as sucralfates and are medications primarily taken to treat active duodenal ulcers. They are also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.  Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.</p>

<p>Methyl syringate 4-O-beta-D-gentiobiose is a modification, which is an oligosaccharide carbohydrate complex. It is synthesized by custom synthesis and has a high purity. It is a CAS number and has the molecular formula C12H20O9. This compound can be found in nature as a monosaccharide or polysaccharide sugar. The methylation of this compound can produce methyl syringate 4-O-beta-D-gentiobiose.</p>

<p>Trehalose is a naturally occurring disaccharide found in many organisms. Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesised by cells in response to stress and helps retaining the cellular integrity under tough conditions. An important function of trehalose is to stabilise protein structures and to prevent proteins from their degradation. Researchers use trehalose for instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>The bianntennary N-linked core pentasaccharide is an oligosaccharide that contains a biantennary glycan and a high purity. This product can be custom synthesized with custom modifications. The bianntennary N-linked core pentasaccharide is an excellent substrate for Click modification, fluorination, and glycosylation reactions. It has been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) in the guinea pig erythrocyte assay. This product has been methylated at the 6 position of the sugar moiety to yield a modified form.</p>

<p>A natural structural element in a variety of glycoconjugates. Substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar and for characterizing lectins.</p>

<p>Sialyllacto-N-fucopentaose I is a high purity, custom synthesis, fluorinated carbohydrate that has been modified by methylation and click chemistry. This oligosaccharide is composed of a saccharide with a molecular weight of 908.5 g/mol and an enantiomeric purity of 99%. Sialyllacto-N-fucopentaose I is an Oligosaccharide with a CAS number of 61497-04-8. It is used in the synthesis of polysaccharides or as a monosaccharide or sugar substitute to produce high purity products.</p>

<p>NA2 is a glycan that is a specific antigen binding molecule. It binds to the CD20 receptor on the surface of human B lymphocytes, which are involved in the development of cancer and inflammatory diseases. NA2 can be used for the treatment of these diseases, as well as cancers that express CD20 receptors. NA2 is generated from endogenous molecules that have been modified by introducing galactose into the carbohydrate backbone. These molecules also form a linker with bendamustine, which is an anticancer drug.</p>

<p>Acarviosin is a chemical compound that is structurally related to the antimicrobial peptide Ac-LLL-Nal-OH. It is an antidiabetic agent that has been shown to be effective for the treatment of type 2 diabetes and associated cardiovascular risk factors. Acarviosin was originally isolated from a bacterial strain and has been chemically synthesized for use in the treatment of diabetes. Acarviosin inhibits both glycan synthesis and enzyme activities, leading to reduced levels of glucose in blood plasma. This drug also exhibits pharmacokinetic properties with a half-life of approximately 15 hours, which allows it to be taken once daily. Acarviosin can also be used as an analytical method for identifying disaccharides by cleaving them at the glycosidic bond, releasing monosaccharides as products.</p>

<p>Nematode glycan mediating activation of macrophages</p>

<p>The structure of GD2-oligosaccharide-sp-biotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) with two sialic acids linked (β-2,3/β-2,8) to the central galactose residue and biotin attached to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy.</p>

<p>Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This tetrasaccharide ammonium salt and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).</p>

<p>4-O-(4-O-(a-D-Glucopyranosyl)-a-D-glucopyranosyl)-b-D-thioglucopyranose is a glycosylation product of the sugar 4-O-(4-O-(a-D-glucopyranosyl)-a-D-glucopyranosyl) b -D -thioglucopyranose. It is synthesized by reaction of 4,5,6,7,8,9,10,11,12,13,14 and 15 with a 1:1 molar ratio. The product can be modified to methylated or fluorinated products using the click chemistry method.</p>

<p>Biotin-labelled oligosaccharide domain of the monosialylated glycosphingolipid GM2 of a-series. The compound is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system. GM2 is also overexpressed in melanomas and other tumours of neuro-ecto origin. Moreover, the sugar moiety of this ganglioside is a receptor allowing viral infection of cells with reovirus and rotavirus.</p>

<p>Lewis A is a trisaccharide that has been found to be present in the glycan structures of spermatozoa. It has also been identified as a major component of the glycan structures on the surface of HL-60 cells. Lewis A is composed of three monosaccharides, galactose, fucose, and N-acetylgalactosamine, which are linked together with a beta (1→4) linkage. The hydroxyl group on the galactose molecule allows for steric interactions with neighboring sugar molecules through hydrogen bonding and van der Waals forces. The Lewis A trisaccharide is an important marker for identifying blood type O because it does not have any antigenic determinants that can cause an immune response.</p>

<p>Glycyl-Oligosaccharidesmannose 3(a) (GL3(a)) is a complex carbohydrate that is composed of mannose and glycyl chains. It has been modified with methyl, click, fluorination, and saccharide modifications. GL3(a) has been synthesized using custom synthesis methods that yield high purity.</p>

<p>4-Methoxyphenyl 4-O-(2,4,6-tri-O-acetyl-3-O-allyl-b-D-galactopyranosyl)-3-O-allyl-b-Dglucopyranoside is a synthetic sugar with a molecular weight of 532. This product can be used in the synthesis of oligosaccharides and monosaccharides. It is also used as an intermediate in glycosylation reactions. This product has not been assigned a CAS number yet.</p>

<p>LacDiNAc dimer ethylazide is a modified form of LacdiNAc that has been iodinated. It is synthesized by the reaction of two molecules of LacdiNAc with ethylazide. The product has an average molecular weight of 2,000 and is the most highly purified synthetic carbohydrate available. It can be used in a wide range of applications, including click chemistry, glycosylation reactions, and fluorination synthesis.</p>

<p>N-[2-Acetamido-2-deoxy-6-O-(a-L-fucopyranosyl)-D-glucopyranosyl]-L-asparagine is a custom synthesis methylated oligosaccharide with a molecular weight of 732.13 Da. It has been fluorinated, modified and saccharide methylated. N-[2-Acetamido-2-deoxy-6-O-(a-L-fucopyranosyl)-D-glucopyranosyl]-L asparagine is soluble in water and has a purity of &gt;98%. The chemical name for this compound is 2-[(5Z,6E)-5,6,7,8,9,10,11,12,13,14,15,16] -octadecahydro--[1H] -indeno[1',3':4',5]pyrrol</p>

<p>A-BSA is an antibody that competes with the blood group antigen for binding to erythrocytes. The A-BSA is immobilized on a microtitre plate and incubated with the blood group antigen and human blood group antiserum. The concentration of A-BSA in the solution is determined by measuring the enzyme-linked immunosorbent assay (ELISA) signal using a spectrophotometer. This measurement is used to determine the concentration of blood group antigen in the sample.</p>

<p>Ai Product Descriptions 50 Creative</p>

<p>Synthesized by the 4,6-O-benzylidene acetal-controlled method of Crich</p>