Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3413 produits trouvés pour "Nucléosides et Nucléotides"
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Cladribine
CAS :<p>Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.</p>Formule :C10H12ClN5O3Degré de pureté :99.58% - >99.99%Couleur et forme :White Crystalline SolidMasse moléculaire :285.69CNQX disodium
CAS :<p>CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.</p>Formule :C9H2N4Na2O4Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :276.12Desciclovir
CAS :<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Formule :C8H11N5O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :209.21Enprofylline
CAS :<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Formule :C8H10N4O2Degré de pureté :98.37%Couleur et forme :SolidMasse moléculaire :194.19Nelarabine
CAS :<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Formule :C11H15N5O5Degré de pureté :98.10% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Deoxycytidine triphosphate trisodium salt
CAS :<p>Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.</p>Formule :C9H13N3Na3O13P3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :533.1Azvudine
CAS :<p>Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.</p>Formule :C9H11FN6O4Degré de pureté :99.76% - >99.99%Couleur et forme :SolidMasse moléculaire :286.22Diquafosol tetrasodium
CAS :<p>Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film</p>Formule :C18H22N4Na4O23P4Degré de pureté :98.25% - 99.97%Couleur et forme :SolidMasse moléculaire :878.23Deoxycytidine triphosphate
CAS :<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formule :C9H16N3O13P3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :467.16Creatine
CAS :<p>Creatine, an amino acid in vertebrates, forms phosphocreatine in muscle, aids energy transfer, is made in the liver, and mainly stored in muscles.</p>Formule :C4H9N3O2Degré de pureté :99.63% - 99.83%Couleur et forme :Colourless To Light Yellow SolidMasse moléculaire :131.13Adenosine 5'-diphosphate
CAS :<p>Adenosine 5'-diphosphate (ADP) is a natural nucleotide derived from the dephosphorylation of ATP. ADP induces platelet aggregation. Cost effective and quality assured.</p>Formule :C10H15N5O10P2Degré de pureté :99.5% - >99.99%Couleur et forme :SolidMasse moléculaire :427.2Lamivudine
CAS :<p>Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.</p>Formule :C8H11N3O3SDegré de pureté :99.56% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :229.26Melamine
CAS :<p>Melamine is used for making resin, and forms in mammals after eating cyromazine.</p>Formule :C3H6N6Degré de pureté :99.49%Couleur et forme :White Solid PowderMasse moléculaire :126.12Uridine triphosphate trisodium salt
CAS :<p>Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.</p>Formule :C9H12N2Na3O15P3Degré de pureté :99.82% - 99.83%Couleur et forme :White PowderMasse moléculaire :550.09ATP
CAS :<p>ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis.</p>Formule :C10H16N5O13P3Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :507.18Levomefolic Acid-d5 (L-5-Methyltetrahydrofolic Acid-d5)
Formule :C20H20N7O6D5Masse moléculaire :464.50Adefovir
CAS :<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Formule :C8H12N5O4PDegré de pureté :99.56%Couleur et forme :White To Off-White PowderMasse moléculaire :273.19Cabotegravir
CAS :<p>Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (</p>Formule :C19H17F2N3O5Degré de pureté :98.55% - 99.92%Couleur et forme :SolidMasse moléculaire :405.352-Aminopurine
CAS :<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Formule :C5H5N5Degré de pureté :99.51%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :135.13Caroverine hydrochloride
CAS :<p>Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.</p>Formule :C22H28ClN3O2Degré de pureté :98.37% - 98.75%Couleur et forme :SolidMasse moléculaire :401.9Cidofovir
CAS :<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Formule :C8H14N3O6PDegré de pureté :99.24% - 99.76%Couleur et forme :Fluffy White PowderMasse moléculaire :279.19CX516
CAS :<p>CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.</p>Formule :C14H15N3ODegré de pureté :99.04% - ≥95%Couleur et forme :Tan SolidMasse moléculaire :241.29S29434
CAS :<p>S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).</p>Formule :C21H18N4O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :374.39Inosine
CAS :<p>Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Low-Cost!</p>Formule :C10H12N4O5Degré de pureté :99.51% - 99.89%Couleur et forme :SolidMasse moléculaire :268.23Peramivir Trihydrate
CAS :<p>Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are</p>Formule :C15H28N4O4·3H2ODegré de pureté :99.52% - ≥95%Couleur et forme :SolidMasse moléculaire :382.45Dapagliflozin
CAS :<p>Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.</p>Formule :C21H25ClO6Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :408.87cangrelor tetrasodium
CAS :<p>Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.</p>Formule :C17H21Cl2F3N5Na4O12P3S2Degré de pureté :98.51% - 98.6%Couleur et forme :SolidMasse moléculaire :864.29Etravirine
CAS :<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Formule :C20H15BrN6ODegré de pureté :97.61% - 99.74%Couleur et forme :White To Off-White SolidMasse moléculaire :435.28IDRA-21
CAS :<p>IDRA-21 is a positive AMPA receptor modulator.</p>Formule :C8H9ClN2O2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :232.69Levomefolate calcium
CAS :<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Formule :C20H23CaN7O6Degré de pureté :97.35%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :497.52Dexelvucitabine
CAS :<p>Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formule :C9H10FN3O3Degré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :227.19Cidofovir dihydrate
CAS :<p>Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.</p>Formule :C8H18N3O8PDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :315.22Fludarabine Phosphate
CAS :<p>Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.</p>Formule :C10H13FN5O7PDegré de pureté :99.25% - 99.78%Couleur et forme :SolidMasse moléculaire :365.21Hibifolin
CAS :<p>Hibifolin is a flavonol glycoside natural product,is a potential inhibitor of adenosine deaminase (Ki of 49.92 μM).</p>Formule :C21H18O14Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :494.361,5-Isoquinolinediol
CAS :<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formule :C9H7NO2Degré de pureté :98.29% - 99.35%Couleur et forme :Of White To White PowderMasse moléculaire :161.16Dilazep dihydrochloride
CAS :<p>Dilazep dihydrochloride inhibits adenosine uptake, ischemia, nucleoside transport, platelet aggregation, and acts as a vasodilator.</p>Formule :C31H46Cl2N2O10Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :677.61Remdesivir
CAS :<p>Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of</p>Formule :C27H35N6O8PDegré de pureté :97.62% - 99.98%Couleur et forme :SolidMasse moléculaire :602.58Uridine
CAS :<p>Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.</p>Formule :C9H12N2O6Degré de pureté :99.08% - 99.82%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :244.2Adenosine monophosphate
CAS :<p>AMP is a purine nucleotide, vital in cell signaling and energy regulation, and inhibits EC 3.1.3.11 and 3.1.3.1, also an A1 receptor agonist.</p>Formule :C10H14N5O7PDegré de pureté :99.59% - 99.84%Couleur et forme :Crystals From Water + Acetone SolidMasse moléculaire :347.22GKT136901
CAS :<p>GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite</p>Formule :C19H15ClN4O2Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :366.8NADPH tetrasodium salt
CAS :<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formule :C21H26N7Na4O17P3Degré de pureté :97.15% - >99.99%Couleur et forme :SolidMasse moléculaire :833.35NADPH tetracyclohexanamine
CAS :<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formule :C45H82N11O17P3Degré de pureté :98.73% - 99.05%Couleur et forme :SolidMasse moléculaire :1142.12Thiamine pyrophosphate chloride
CAS :<p>Thiamine pyrophosphate, a vitamin B1 derivative, is a coenzyme in transketolase studies for decarboxylation in biology.</p>Formule :C12H19ClN4O7P2SDegré de pureté :98.29% - 99.72%Couleur et forme :SolidMasse moléculaire :460.76ASP-9521
CAS :<p>ASP-9521 is a selective, potent and orally active indole-based AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3.Cost-effective and quality-assured.</p>Formule :C19H26N2O3Degré de pureté :95.11% - 96.96%Couleur et forme :SolidMasse moléculaire :330.42Rabeprazole sodium
CAS :<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Formule :C18H20N3NaO3SDegré de pureté :98% - 99.912%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :381.42Ganciclovir sodium
CAS :<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formule :C9H13N5NaO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :278.22Didanosine
CAS :<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Formule :C10H12N4O3Degré de pureté :99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :236.23Cytosine
CAS :<p>Cytosine is a pyrimidine nucleic acid base; its deamination can cause mutations in leukemia and cancer.</p>Formule :C4H5N3ODegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :111.1Sofosbuvir
CAS :<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Formule :C22H29FN3O9PDegré de pureté :99.77% - 99.82%Couleur et forme :SolidMasse moléculaire :529.45Cytidine 5'-monophosphate
CAS :<p>Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA.</p>Formule :C9H14N3O8PDegré de pureté :98.78% - 99.10%Couleur et forme :SolidMasse moléculaire :323.20N2-Nitroso Folinic Acid (N2-Nitroso Folic Acid USP Related Compound A (Free Form), N2-Nitroso Leucovorin)
Formule :C20H22N8O8Masse moléculaire :502.44Flavine Adenine Dinucleotide Disodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase.<br>References DeLuca, K., et al.: J. Biol. Chem., 223, 569 (1956), Yagi, K., et al.: Biochemistry, 19, 1553 (1980), Li, G., et al.: J. Phys. Chem., 112, 4573 (2008),<br></p>Formule :C27H31N9O15P2·2NaCouleur et forme :NeatMasse moléculaire :829.51Viaminate
CAS :Produit contrôlé<p>Applications Viaminate is a pharmaceutical used to treat severe acne and other keratinization disorders. Viaminate can be taken orally, or topically in prepared gels and creams.<br>References Zhang, H.; et al.: Am. J. Med. Sci., 356, 84 (2018); Lu, J.; et al.: Zhongguo Yaofang, 22, 155 (2011); Li, G.: Zhonghua Yiyao Zazhi, 7, 536 (2007).<br></p>Formule :C29H37NO3Couleur et forme :Light YellowMasse moléculaire :447.61Entecavir
CAS :<p>Applications An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.28Canagliflozin 2-Glucuronide
CAS :Produit contrôlé<p>Applications Canagliflozin 2-glucuronide is a derivative of Canagliflozin (C175190). Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion.<br>References Devineni, D., et al.: Diab. Obes. Metab., 14, 539 (2012); Nicolle, L., et al.: Curr. Med. Res. Opin., 28, 1167 (2012)<br></p>Formule :C30H33FO11SCouleur et forme :NeatMasse moléculaire :620.64Penciclovir
CAS :<p>Applications An antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Formule :C10H15N5O3Couleur et forme :NeatMasse moléculaire :253.265-Methyluridine
CAS :<p>Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.<br>References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),<br></p>Formule :C10H14N2O6Couleur et forme :NeatMasse moléculaire :258.23Adenosine 5'-Monophosphate
CAS :Produit contrôlé<p>Applications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.<br>References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)<br></p>Formule :C10H14N5O7PCouleur et forme :NeatMasse moléculaire :347.225-Methyl-2’-deoxy Cytidine
CAS :<p>Applications A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).<br>References Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008),<br></p>Formule :C10H15N3O4Couleur et forme :NeatMasse moléculaire :241.243’-Amino-3’-deoxythymidine
CAS :Produit contrôlé<p>Impurity Zidovudine Impurity;<br>Stability Hygroscopic, Moisture Sensitive<br>Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT).<br>References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),<br></p>Formule :C10H15N3O4Couleur et forme :White To Off-WhiteMasse moléculaire :241.24Entecavir-13C2,15N
CAS :Produit contrôlé<p>Applications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Formule :C1013C2H15N415NO3Couleur et forme :White To Off-WhiteMasse moléculaire :280.264’-Epi Lamivudine
CAS :Produit contrôlé<p>Applications Lamivudine epimer.<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Formule :C8H11N3O3SCouleur et forme :NeatMasse moléculaire :229.26RO 2433
CAS :Produit contrôlé<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Formule :C10H13FN2O5Couleur et forme :NeatMasse moléculaire :260.223’,5’-Di-O-benzyl Entecavir
CAS :Produit contrôlé<p>Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).<br>References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Formule :C26H27N5O3Couleur et forme :NeatMasse moléculaire :457.52cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS :Produit contrôlé<p>Applications Antiviral nucleoside analog, also an impurity found in emtricitabine (E525000).<br>References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Formule :C8H9FN2O4SCouleur et forme :Off-WhiteMasse moléculaire :248.23Folic Acid-13C5
CAS :<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Formule :C5C14H19N7O6Couleur et forme :Dark Yellow To Dark BrownMasse moléculaire :446.362-Oxa-1,4-butanediol diacetate
CAS :Produit contrôléFormule :C7H12O5Couleur et forme :NeatMasse moléculaire :176.17trans-Abacavir Dihydrochloride
CAS :Produit contrôlé<p>Applications trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Formule :C14H18N6O·2HClCouleur et forme :NeatMasse moléculaire :359.25Adenosine 5’-Monophosphoramidate Sodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Used in the characterization and elucidation of coordination requirements of adenine nucleotides complexes with Fe(II) ions.<br>References Richter, Y., et al.: Nucleos. Nucleot. Nucleic Acids, 22, 1757 (2003),<br></p>Formule :C10H14N6O6P·NaCouleur et forme :NeatMasse moléculaire :368.22O-Benzoyllamivudine
CAS :Produit contrôléFormule :C15H15N3O4SCouleur et forme :Off-WhiteMasse moléculaire :333.362N2-Acetyl Acyclovir
CAS :Produit contrôlé<p>Impurity Aciclovir EP Impurity F<br>Applications N2-Acetyl Acyclovir (Aciclovir EP Impurity F) is an impurity of Acyclovir (A192400).<br>References Balon, K., et al.: Pharm. Res., 16, 882 (1999),<br></p>Formule :C10H13N5O4Couleur et forme :BeigeMasse moléculaire :267.245-Fluoro ent-Lamivudine Acid D-Menthol Ester
CAS :Produit contrôlé<p>Applications Intermediate in the synthesis of ent-Emtricitabine (E525005).<br></p>Formule :C18H26FN3O4SCouleur et forme :NeatMasse moléculaire :399.486-Deoxypenciclovir
CAS :Produit contrôlé<p>Applications A metabolite of Famciclovir, an antiviral.<br>References Harnden, M.R., et al.: J. Med. Chem., 32, 1738 (1989)<br></p>Formule :C10H15N5O2Couleur et forme :Off White SolidMasse moléculaire :237.261R-Dapagliflozin
CAS :Produit contrôlé<p>Applications 1R-Dapagliflozin is an isomer of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formule :C21H25ClO6Couleur et forme :NeatMasse moléculaire :408.883'-Deoxyinosine
CAS :Produit contrôlé<p>Impurity Didanosine EP Impurity D<br>Applications 3'-Deoxyinosine (Didanosine EP Impurity D) is an Inosine (I661000) analog with potential use as an antileishmanial drug. Used as an inhibiting agent in studies of Trypanosoma cruzi growth inside host cells in vitro. An impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950).<br>References Morishige, K. et al.: Exp. Parasitol., 80, 665 (1995); Aoki, T. et al.: Adv. Exp. Med. Biol., 370, 499 (1994);<br></p>Formule :C10H12N4O4Couleur et forme :NeatMasse moléculaire :252.23α-Decitabine
CAS :Produit contrôlé<p>Applications α-Decitabine is shown to inhibit DNA methylation resulting in an effective anticancer agent.<br>References Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);<br></p>Formule :C8H12N4O4Couleur et forme :NeatMasse moléculaire :228.21Capecitabine-d11
CAS :Produit contrôléFormule :C152H11H11FN3O6Couleur et forme :NeatMasse moléculaire :370.422,4-Diamino-6-hydroxypyrimidine
CAS :Produit contrôlé<p>Applications 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.<br></p>Formule :C4H6N4OCouleur et forme :NeatMasse moléculaire :126.12Abacavir-d4
CAS :Produit contrôlé<p>Stability Very Hygroscopic<br>Applications Abacavir-d4 is deuterium labeled Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Formule :C14H14D4N6OCouleur et forme :Off-WhiteMasse moléculaire :290.361’-epi-Cladribine
CAS :<p>Applications 1’-epi-Cladribine is an impurity of Cladribine (C557500), a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990),<br></p>Formule :C10H12ClN5O3Couleur et forme :NeatMasse moléculaire :285.69Folinic acid
CAS :<p>Folinic acid (Leucovorin) is a biofolic acid that can be used in the treatment of methotrexate, often in combination with Methotrexate (MTX) to reduce MTX-</p>Formule :C20H23N7O7Degré de pureté :99.76%Couleur et forme :Crystals From Water With 3 Mol Of Water Of Crystallization SolidMasse moléculaire :473.44Floxuridine-13C,15N2
CAS :Produit contrôlé<p>Applications Labelled Floxuridine. Antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Formule :C813CH11F15N2O5Couleur et forme :WhiteMasse moléculaire :249.17Melamine-15N3
CAS :<p>Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.<br></p>Formule :C3H615N3N3Couleur et forme :White To Off-WhiteMasse moléculaire :129.10Dapagliflozin hydroxy Impurity (Mixture of Diastereomers)
CAS :<p>Applications (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol is an impurity of the drug Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formule :C21H25ClO7Couleur et forme :White To Off-WhiteMasse moléculaire :424.872Laninamivir
CAS :<p>Applications A new potent neuraminidase (NA) inhibitor, shows long-acting anti-influenza virus activity.<br>References Bantia, S., et al.: Antimicrob. Agents Chemother., 42, 801 (1998), Honda, T., et al.: Bioorg. Med. Chem. Lett., 12, 1925 (2002), Kiso, M., et al.: Lancet, 364, 759 (2004), Macdonald, S., et al.: J. Med. Chem., 48, 2964 (2005),<br></p>Formule :C13H22N4O7Couleur et forme :White To Off-WhiteMasse moléculaire :346.34Zanamivir
CAS :Produit contrôlé<p>Applications Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral.<br>References Woods, J.M., et al.: Antimicrob. Agents Chemother., 37, 1473 (1993), Pegg, M.S., et al.: Biochem. Mol. Biol. Int., 32, 851 (1994), Monto, A.S., et al.: J. Am. Med. Assoc., 282, 31 (1999),<br></p>Formule :C12H20N4O7Couleur et forme :NeatMasse moléculaire :332.31Barbituric Acid
CAS :<p>Impurity Fluorouracil EP Impurity A<br>Applications Barbituric Acid (Fluorouracil EP Impurity A) is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties.<br>References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),<br></p>Formule :C4H4N2O3Couleur et forme :NeatMasse moléculaire :128.09Adenosine-3’,5’-cyclic Monophosphate
CAS :<p>Stability Hygroscopic<br>Applications Adenosine-3’,5’-cyclic Monophosphate is an Adenosine (A280400) derivative useful as anticancer agent.<br>References Keast, R., et al.: Pharma. Res., 19, 1019 (2002),<br></p>Formule :C10H12N5O6PCouleur et forme :NeatMasse moléculaire :329.21[1',2',3',4',5'-13C5]Uridine
CAS :Produit contrôlé<p>Applications Labelled Uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)<br>References Lorine, P., et al.: J. Biol. Chem., 178, 439 (1949); Grakoui, A., et al.: J. Virol., 63, 5216 (1989); Strauss, J., et al.: Microbiol. Rev., 58, 491 (1994); Lin, Y., et al.: Virology, 292, 78 (2002);<br></p>Formule :C5C4H12N2O6Couleur et forme :NeatMasse moléculaire :249.16Etravirine
CAS :Produit contrôlé<p>Applications Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection.<br>References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008), Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008),<br></p>Formule :C20H15BrN6OCouleur et forme :White To Off-WhiteMasse moléculaire :435.281,3-Dioxolane (Stabilized with BHT)
CAS :Produit contrôléFormule :C3H6O2Couleur et forme :NeatMasse moléculaire :74.08Baquiloprim
CAS :<p>Stability Hygroscopic<br>Applications Baquiloprim is an amiopyrimidine antibacterial synergist with high activity and slow elimination. Baquiloprim has a better half-life than trimethoprim.<br>References Zhi-hui, H., et al.: Anhui Nongye Kexue, 41, 2503 (2013)<br></p>Formule :C17H20N6Couleur et forme :Light YellowMasse moléculaire :308.382’-Deoxycytidine 5'-Monophosphate Hydrate
CAS :Produit contrôlé<p>Applications A phosphorylated metabolite of the deoxyribonucleoside 2’-Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferation.<br>References Holen, E. et al.: Nutrition, 21, 1003 (2005); Alexandre, J.A. et al.: Nucleosides Nucleotides Nucelic Acids, 26, 1375 (2007);<br></p>Formule :C9H14N3O7P·xH2OCouleur et forme :White To Off-WhiteMasse moléculaire :307.20 + x(18.02)5-Aza Cytosine
CAS :Produit contrôlé<p>Impurity Azacitidine USP Related Compound A<br>Applications Inhibits the growth of Escherichia coli. Azacitidine USP Related Compound A.<br>References Shapir, N., et al.: J. Bacteriol., 184, 5376 (2002), Hrdlicka, P., et al.: Bioorg. Med. Chem., 13, 1249 (2005), Krecmerova, M., et al.: J. Med. Chem., 50, 1069 (2007),<br></p>Formule :C3H4N4OCouleur et forme :White SolidMasse moléculaire :112.09Gemcitabine-13C,15N2 Hydrochloride
CAS :<p>Stability Hygroscopic<br>Applications Labelled Gemcitabine, an antineoplastic.<br>References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),<br></p>Formule :C813CH12ClF2N15N2O4Couleur et forme :Off-WhiteMasse moléculaire :302.64D-Glucono-1,5-lactone
CAS :Produit contrôlé<p>Applications A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.<br>References Jacob, M. et al.: Food Hydrocoll., 25, 928 (2011); Li, J. et al.: J. Sci. Food Agric., 91, 38, 2011;<br></p>Formule :C6H10O6Couleur et forme :NeatMasse moléculaire :178.142’,2’-Difluoro-2’-deoxyuridine
CAS :Produit contrôléFormule :C9H10F2N2O5Couleur et forme :White To Off-WhiteMasse moléculaire :264.184-[(2-Chloroethyl)amino]-L-phenylalanine Dihydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 4-[(2-Chloroethyl)amino]-L-phenylalanine is a metabolite of Melphalan (M216900); an antineoplastic.<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)<br></p>Formule :C11H15ClN2O2HClCouleur et forme :NeatMasse moléculaire :242.702Dapagliflozin Tetraacetate
CAS :<p>Applications Dapagliflozin Tetraacetate is a derivative of Dapagliflozin [D226255], a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Formule :C29H33ClO10Couleur et forme :WhiteMasse moléculaire :577.02ent-Entecavir
CAS :Produit contrôlé<p>Applications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900).<br>References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.285-Fluoro Cytosine
CAS :Produit contrôlé<p>Applications 5-FC is a toxic antifungal/antimicrobial agent.<br>References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),<br></p>Formule :C4H4FN3OCouleur et forme :White To Off-WhiteMasse moléculaire :129.09Ribavirin-13C2
CAS :Produit contrôlé<p>Applications Ribavirin-13C2 is the labeled analogue of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986); Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993); Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994); Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Formule :C613C2H12N4O5Couleur et forme :WhiteMasse moléculaire :246.19α-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS :Produit contrôléFormule :C22H18Cl2N4O6Couleur et forme :White To Off-WhiteMasse moléculaire :505.308Adenosine-13C5
CAS :<p>Stability Hygroscopic<br>Applications Labelled nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010), Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010),<br></p>Formule :C513C5H13N5O4Couleur et forme :White To Off-WhiteMasse moléculaire :272.20N-Des-1-β-D-ribofuranosyl Ribavirin
CAS :<p>Impurity Ribavirin EP Impurity D<br>Applications N-Des-1-β-D-ribofuranosyl Ribavirin (Ribavirin EP Impurity D) is an impurity in the synthesis of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Formule :C3H4N4OCouleur et forme :Off White SolidMasse moléculaire :112.09Decarboxylated S-Adenosylmethionine Sulfate Salt
CAS :<p>Stability Hygroscopic<br>Applications Decarboxylated S-Adenosylmethionine Sulfate Salt, is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.<br>References Takahashi,T., et al.: Ann. Bot., 105, 1 (2009); Wu, H., et al.: Biochem., 46, 8331 (2007); Pegg, A., et al.: Biochem., 28, 8446 (1989);<br></p>Formule :C14H23N6O3S•H2SO4•HSO4Couleur et forme :White SolidMasse moléculaire :355.4498079706Ammeline
CAS :<p>Applications Ammeline is a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Formule :C3H5N5OCouleur et forme :ColourlessMasse moléculaire :127.10Cabotegravir-d3
CAS :Produit contrôléFormule :C19H14D3F2N3O5Couleur et forme :NeatMasse moléculaire :408.37Dapagliflozin 3-O-β-D-Glucuronide
CAS :Produit contrôléFormule :C27H33ClO12Couleur et forme :NeatMasse moléculaire :584.9975’-Deoxy-5-fluorocytidine-13C,15N2
CAS :Produit contrôlé<p>Applications A labelled metabolite of Capecitabine.<br></p>Formule :C813CH12FN15N2O4Couleur et forme :NeatMasse moléculaire :248.191-β-D-Arabinofuranosyluracil
CAS :<p>Impurity Cytarabine EP Impurity A<br>Applications Antiviral agent. Used for the treatment of severe acute respiratory syndrome (SARS).<br>References Weber, G., et al.: Cancer Res., 43, 3466 (1983), Broet, P., et al.: J. Clin. Oncol., 19, 2778 (2001), Galmarini, C., et al.: Leukemia, 15, 875 (2001), Barth, R., et al.: Cancer Res., 64, 6287 (2004), Song, M., et al.: Bioorg. Med. Chem., 12, 489 (2004),<br></p>Formule :C9H12N2O6Couleur et forme :WhiteMasse moléculaire :244.20N-Methyltetrahydrofolic Acid
CAS :Produit contrôlé<p>Applications N-Methyltetrahydrofolic acid (cas# 134-35-0) is a useful research chemical.<br></p>Formule :C20H25N7O6Couleur et forme :NeatMasse moléculaire :459.46O-[(Guanin-9-yl)methyl] Acyclovir
CAS :<p>Impurity Aciclovir EP Impurity J<br>Applications O-(Guanin-9-yl)methyl Acyclovir (Aciclovir EP Impurity J) is a dimer impurity of the antiviral agent Acyclovir (A192400).<br>References Ashton, D.S. et al.: J. Chrom. A, 707, 367 (1995);<br></p>Formule :C14H16N10O4Couleur et forme :BeigeMasse moléculaire :388.343'-Azido-3'-deoxythymidine
CAS :Produit contrôlé<p>Applications A potent and selective inhibitor of HIV-1 replication.<br>References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),<br></p>Formule :C10H13N5O4Couleur et forme :White To YellowMasse moléculaire :267.24Biopterin-d3
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled Biopterin. A pteridine widely distributed in nature; naturally occurring as the L-erythro-form. Considered as a growth factor for some insects. Fluoresces with a blue color in alkaline solution.<br>References Klatt, P., et al.: J. Biol. Chem., 269, 13861 (1994), Mitnaul, L., et al.: Biochemistry, 92, 885 (1995), Thony, B., et al.: Biochem. J., 347, 1 (2000),<br></p>Formule :C92H3H8N5O3Couleur et forme :Beige To BrownMasse moléculaire :240.234-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
CAS :<p>Applications 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formule :C13H16FN3O6Couleur et forme :Off White PowderMasse moléculaire :329.28(-)-Inosine
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Has neuroprotective properties improving axonal wiring. Has been used to treat stroke patients to restore neural function. Neuroprotective product.<br>References Vandemeulebroucke, A., et al.: Biochem., 49, 8999 (2010), Nestor, G., et al.: J. Agric. Food Chem., 58, 10799 (2010),<br></p>Formule :C10H12N4O5Couleur et forme :White To Off-WhiteMasse moléculaire :268.235-Chloro-1-methyl-4-nitroimidazole
CAS :Produit contrôlé<p>Impurity Azathioprine EP Impurity C<br>Applications 5-Chloro-1-methyl-4-nitroimidazole (cas# 4897-25-0) is a compound useful in organic synthesis.<br></p>Formule :C4H4ClN3O2Couleur et forme :White To Off-WhiteMasse moléculaire :161.551-(Diaminomethylene)-3-b-D-ribofuranosyl-urea Picrate
CAS :Produit contrôlé<p>Impurity Azacitidine USP Related Compound C<br>Stability Hygroscopic<br>Applications 1-(Diaminomethylene)-3-β-D-ribofuranosyl-urea Picrate is a related compound of Azacitidine, a DNA metnyltransferase (DNMT) inhibitor for treating myelodysplastic syndromes (MDS).<br>References Rajendiran, C., et al.: PCT Int. Appl. WO 2012135405 A1 20121004 (2012); Ziemba, A., et al.: Chemother Res Pract 965826, 9 (2011); Beisler, J. A., et al.: J. Carbohyd. Chem 4, 281 (1977)<br></p>Formule :C7H14N4O5·C6H3N3O7Couleur et forme :YellowMasse moléculaire :463.31N-Formyl Valacyclovir
CAS :Produit contrôlé<p>Impurity Valaciclovir EP Impurity M<br>Applications N-Formyl Valacyclovir (Valaciclovir EP Impurity M) Valacyclovir (V085000) impurity.<br>References Furman, P., et al.: Antimicrob. Agents Chemother., 20, 518 (1981),<br></p>Formule :C14H20N6O5Couleur et forme :White To Off-WhiteMasse moléculaire :352.355’-Deoxy-5-fluorouridine
CAS :Produit contrôlé<p>Impurity USP Capecitabine Related Compound B<br>Applications 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.<br>References Ingle, J., et al.: Cancer, 67, 886 (1991); Harvey, J., et al.: J. Clin. Oncol., 17, 1474 (1999); Asai-Sato, M., et al.: Int. J. Cancer, 115, 539 (2005); Rastelli, F., et al.: Tumori, 94, 370 (2008);<br></p>Formule :C9H11FN2O5Couleur et forme :NeatMasse moléculaire :246.19Acetyl Vitamin B12
CAS :<p>Applications Acetyl Vitamin B12 is a derivative of Vitamin B12 (V676020). Vitamin B12 gets converted by the body into its bioactive forms, methylcobalamin and cobamamide, which serve as enzyme cofactors. Severe deficiency may result in megaloblastic anemia and/or neurological impairment.<br>References Rickes, et al.: Science, 107, 396 (1948); Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 10, 183 (1981); Grasbeck, R., et al.: Clin. Biochem., 17, 99 (1984)<br></p>Formule :C65H90CoN14O15PDegré de pureté :>85%Couleur et forme :NeatMasse moléculaire :1397.405-Fluorouracil-13C,15N2
CAS :<p>Applications Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 221 (1973), Miyashita, O., et al.: Chem. Pharm. Bull., 29, 3181 (1981), Hansen, R.M., et al.: Cancer Invest., 9, 637 (1991),<br></p>Formule :C313CH3F15N2O2Couleur et forme :NeatMasse moléculaire :133.06Capecitabine-2',3'-cyclic Carbonate
CAS :Produit contrôlé<p>Impurity Capecitabine EP Impurity F/ USP Capecitabine Related Compound C<br>Applications Capecitabine-2',3'-cyclic Carbonate (Capecitabine EP Impurity F) is a capecitabine related compound C is an impurity in Capecitabine (C175650), an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formule :C16H20FN3O7Couleur et forme :NeatMasse moléculaire :385.34Emtricitabine Tenofovir Monosoproxil
Produit contrôlé<p>Stability Hygrscopic<br>Applications Emtricitabine Tenofovir Monosoproxil is a derivative of Emtricitabine (E525000). Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Formule :C23H32FN8O10PSCouleur et forme :NeatMasse moléculaire :662.58Zalcitabine
CAS :Produit contrôlé<p>Applications A pyrimidine nucleoside analogue with antiviral activity.<br>References van der Vliet, P.C. and Kwant, M.M.: Biochemistry, 20, 2628 (1981), Mitsuya, H., Broder, S.: Proc. Nat. Acad. Sci. USA, 83, 1911 (1986), Starnes, M.C., and Cheng, Y.: J. Biol. Chem., 262, 988 (1987),<br></p>Formule :C9H13N3O3Couleur et forme :NeatMasse moléculaire :211.22D-2’-Deoxyribofuranosyl-3-guanylurea(α/β-Mixture)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Hydrolytic impurity of D226730 and A796950 (decitabine)<br>References Beisler, Jj.A., et al.: J. Med. Chem., 21, 204 (1978),<br></p>Formule :C7H14N4O4Couleur et forme :NeatMasse moléculaire :218.2105Lamivudine-13C1,d2
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Lamivudine-13C1,d2, is the labeled analogue of Lamivudine (L172502). A reverse transcriptase inhibitor. Antiviral.<br>References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),<br></p>Formule :C713CH9D2N3O3SCouleur et forme :White PowderMasse moléculaire :232.26Canagliflozin
CAS :Produit contrôlé<p>Applications Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.<br>References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);<br></p>Formule :C24H25FO5SCouleur et forme :ColourlessMasse moléculaire :444.52Lamivudine
CAS :Produit contrôlé<p>Applications Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.<br>References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),<br></p>Formule :C8H11N3O3SCouleur et forme :WhiteMasse moléculaire :229.26Cobamamide
CAS :Produit contrôlé<p>Applications Cobamamide is an enzyme cofactor that can also regulate gene expression through RNA-base riboswitches.<br>References Ortiz-Guerrero, J.M., et. al.: P. Natl. Acad. Sci. USA, 108, 7565 (2011)<br></p>Formule :C72H100CoN18O17PCouleur et forme :NeatMasse moléculaire :1579.585-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt (>90%)
CAS :Produit contrôlé<p>Impurity Azathioprine BP Impurity E<br>Stability Light Sensitive<br>Applications 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt is a degradation product of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).<br>References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)<br></p>Formule :C4H4N3NaO3Degré de pureté :>90%Couleur et forme :Light Yellow To YellowMasse moléculaire :165.082-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate
CAS :Produit contrôlé<p>Applications Gemcitabine intermediate.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),<br></p>Formule :C19H16F2O6Couleur et forme :Colourless To BrownMasse moléculaire :378.32Emtricitabine
CAS :<p>Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Formule :C8H10FN3O3SCouleur et forme :Light YellowMasse moléculaire :247.255-Chlorouracil
CAS :Produit contrôlé<p>Impurity Fluorouracil EP Impurity E<br>Applications Used for the experimental and clinical treatment of neoplastic and viral diseases. Fluorouracil EP Impurity E.<br>References Yu, H., et al.: J. Biol. Chem., 268, 15935 (1993), Staleva, L., et al.: Mutat. Res., 370, 81(1996), Harris, V., et al.: J. Mol. Biol., 326, 1389 (2003)<br></p>Formule :C4H3ClN2O2Couleur et forme :NeatMasse moléculaire :146.532’,3’-Dideoxyinosine
CAS :Produit contrôlé<p>Applications 2’,3’-Dideoxyinosine is a purine analog (1) which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2).<br>References 1. Esplugues, J. et al.: AIDS. 2016 Jun 1;30(9):1341-51.2. Blas-Garcia, A. et al.: J. Antimicrob. Chemother. 2016 Apr;71(4):916-26<br></p>Formule :C10H12N4O3Couleur et forme :NeatMasse moléculaire :236.23Cladribine
CAS :<p>Applications It is a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990);<br></p>Formule :C10H12ClN5O3Couleur et forme :White To Light YellowMasse moléculaire :285.692'-Deoxyadenosine Monohydrate
CAS :Produit contrôlé<p>Applications 2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.<br>References Gordon, C., et al.: J. Med. Chem., 48, 1 (2005), Ikejiri, M., et al.: Bioorg. Med. Chem., 15, 6882 (2007),<br></p>Formule :C10H13N5O3·H2OCouleur et forme :NeatMasse moléculaire :269.26Coenzyme Q9
CAS :<p>Applications Antibacterial and antioxidant for preventing and treating cancer.<br>References Itoh, K., et al.: J. Immunol., 170, 3688 (2003), Liu, A., et al.: J. Biol. Chem., 279, 53196 (2004), Wullaert, A., et al.: Biochem. Pharmacol., 72, 1090 (2006),<br></p>Formule :C54H82O4Couleur et forme :YellowMasse moléculaire :795.23Adenosine-15N
CAS :Produit contrôlé<p>Applications Nitrogen 15 labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formule :C10H1315NN4O4Couleur et forme :NeatMasse moléculaire :268.2354’,6-Diamidino-2-phenylindole Dihydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A cell-permeable DNA-binding dye. Binds preferentially to DNA rich in adenine and thymine. Used in flow cytometry for measuring nuclear DNA content or for sorting isolated chromosomes.<br>References Jpeeesen, C, and Nielsen, P.E.: Eur. J. Biochem., 182, 437 (1989), Li,J., et al.: J. Exp. Biol., 200, 1499 (1997), Zaitsev, E.N., and Kowalczykowsi, S.C.: Nucl. Acids Res., 26(2), 650 (1998), Germ, M., et al.: Biochem. Biophys. Res. Commun., 261, 452 (1999),<br></p>Formule :C16H15N5·2ClHCouleur et forme :Yellow PowderMasse moléculaire :350.25Dapagliflozin C2 Epimer
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Dapagliflozin C2 Epimer is an intermediate used in the synthesis of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Majewski, A., et al.: Przemysl Chemiczny, 95, 1129 (2016); Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formule :C21H25ClO6Couleur et forme :NeatMasse moléculaire :408.87(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS :<p>Applications (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile is a predominant metabolite of remdesivir with great potential for Covid-19 treatment.<br>References Yan, V. C., et al.: ACS Med. Chem., 11, 1361 (2020)<br></p>Formule :C12H13N5O4Couleur et forme :NeatMasse moléculaire :291.2627Triethyl Methanetricarboxylate
CAS :Produit contrôlé<p>Applications Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.<br>References Day, J. et al.: Chem. A Eur. J., 16, 2758 (2010); Sechi, M. et al.: Bioorg. Med. Chem., 17, 2925 (2009);<br></p>Formule :C10H16O6Couleur et forme :NeatMasse moléculaire :232.235-Fluorouracil-6-d1
CAS :Produit contrôléFormule :C4H2DFN2O2Couleur et forme :NeatMasse moléculaire :131.08Ammeline-13C3 Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Isotope labelled Ammeline (A633660), which s a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Formule :C3H5N5O·ClHCouleur et forme :NeatMasse moléculaire :166.54Adenosine-5'-13C
CAS :Produit contrôlé<p>Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formule :C913CH13N5O4Couleur et forme :NeatMasse moléculaire :268.24Penciclovir-d4
CAS :Produit contrôlé<p>Applications A deuterated version of Penciclovir, an antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Formule :C102H4H11N5O3Couleur et forme :NeatMasse moléculaire :257.28Ribavirin Carboxylic Acid
CAS :<p>Impurity USP Ribavirin Related Compound A<br>Applications Ribavirin Carboxylic acid is an impurity of Ribavirin (R414475). Ribavirin impurity A.<br>References Lertora, J., et al.: Clin. Pharmacol. Ther., 50, 442 (1991), Connor, E., et al.: Antimicrob. Agents Chemother., 37, 532 (1993), Manns, M., et al.: Lancet, 358, 958 (2001),<br></p>Formule :C8H11N3O6Couleur et forme :NeatMasse moléculaire :245.19Adenosine-5',5''-d2
CAS :Produit contrôlé<p>Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formule :C10H11D2N5O4Couleur et forme :White SolidMasse moléculaire :269.26Abacavir Carboxylate
CAS :<p>Impurity Abacavir - In House Impurity<br>Stability Hygroscopic<br>Applications Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).<br>References (1) Hoetelmans, R., et al.: Pharm. World Sci., 19, 159 (1997) (2) Beach, J., et al.: Clin. Ther., 20, 2 (1998) (3) McDowell, J., et al.: Antimicrob. Agents Chemother., 43, 2855 (1999)<br></p>Formule :C14H16N6O2Couleur et forme :NeatMasse moléculaire :300.32Dapagliflozin Methyl Acetate
CAS :Produit contrôlé<p>Applications Dapagliflozin Methyl Acetate is the impurity of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formule :C23H27ClO7Couleur et forme :NeatMasse moléculaire :450.909L-Valacyclovir Hydrochloride
CAS :Produit contrôlé<p>Applications Acyclovir (A192400) impurity. The L-Valine ester prodrug of Acyclovir.<br>References Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),<br></p>Formule :C13H20N6O4·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :360.80Famciclovir-d4
CAS :Produit contrôlé<p>Applications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral.<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Formule :C142H4H15N5O4Couleur et forme :Off-White To Light BeigeMasse moléculaire :325.36N6-Isopentenyladenosine
CAS :<p>Applications N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells.<br>References Rajabi, M. et al.; DNA Cell Biol.; 29, 687 (2010)<br></p>Formule :C15H21N5O4Couleur et forme :NeatMasse moléculaire :335.365-Fluorodihydropyrimidine-2,4-dione-13C,15N2
CAS :Produit contrôlé<p>Applications A labelled metabolite of 5-Fluorouracil (F596000).<br>References Bocci, G., et al.: Eur. J. Clin. Pharmacol., 58, 593 (2002), Longley, D.B., Nature Rev. Cancer, 3, 330 (2003), Fischel, J., et al.: Anti-Cancer Drugs, 15, 969 (2004)<br></p>Formule :C313CH5F15N2O2Couleur et forme :Off-White To Light BrownMasse moléculaire :135.071-α-Methyl Dapagliflozin
CAS :<p>Stability Hygroscopic<br>Applications 1α-Methyl Dapagliflozin is an antidiabetic agent and intermediate of Dapagliflozin (D226255]), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Formule :C22H27ClO7Couleur et forme :WhiteMasse moléculaire :438.90Dapagliflozin
CAS :<p>Stability Hygroscopic<br>Applications A sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formule :C21H25ClO6Couleur et forme :NeatMasse moléculaire :408.87Ribavirin 5’-Monophosphate Dilithium Salt (90%)
CAS :Produit contrôlé<p>Applications A metabolite of Ribavirin.<br>References Allen, L.B., et al.: J. Med. Chem., 21, 742 (1978), Zimmerman, T., et al.: Biochem. Pharmacol., 27, 709 (1978), Page, T., et al.: Int. J. Biochem., 22, 379 (1990), Lin, C., et al.: Antimicrob. Agents Chemother., 47, 1395 (2003),<br></p>Formule :C17H19N4O9P·2LiDegré de pureté :90%Couleur et forme :Off-White To Light BeigeMasse moléculaire :468.21O6-Benzylguanine
CAS :Produit contrôlé<p>Applications An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.<br>References Dolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)<br></p>Formule :C12H11N5OCouleur et forme :NeatMasse moléculaire :241.25α-Ribavirin (Ribavirin Impurity B)
CAS :Produit contrôléFormule :C8H12N4O5Couleur et forme :NeatMasse moléculaire :244.203'-Azido-3'-deoxythymidine β-D-glucuronide, Sodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.<br></p>Formule :C16H20N5O10·NaCouleur et forme :White To Light YellowMasse moléculaire :465.35Cabotegravir O-β-D-Glucuronide
CAS :Produit contrôlé<p>Applications Cabotegravir O-β-D-Glucuronide is a metabolite of Cabotegravir (C050100), a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.<br>References Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, 397 (2015); Andrews, C. et al.: Sci. Transl. Med., 7, 270 (2015)<br></p>Formule :C25H25F2N3O11Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :581.48Acyclovir Formacetal Dimer (>90%)
<p>Impurity Aciclovir EP Impurity R<br>Applications Acyclovir Formacetal Dimer is a dimer impurity of Acyclovir (A192400); an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also antiviral. (Aciclovir EP Impurity R)<br>References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)<br></p>Formule :C17H22N10O6Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :462.422’-Deoxyadenosine
CAS :<p>Applications 2prime-Deoxyadenosine is a nucleoside adenosine derivative with mutagenic properties.<br></p>Formule :C10H13N5O3Couleur et forme :White To Off-WhiteMasse moléculaire :251.242N-Nitrosodiethylamine (100 ug/mL in Methanol)
CAS :Produit contrôléFormule :C4H10N2OCouleur et forme :Single SolutionMasse moléculaire :102.14Famciclovir
CAS :Produit contrôlé<p>Applications Used as an antiviral. Prodrug of Penciclovir (P221500).<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Formule :C14H19N5O4Couleur et forme :Off-WhiteMasse moléculaire :321.33Peramivir
CAS :<p>Peramivir is a neuraminidase inhibitor used to treat influenza by preventing virus release from cells.</p>Formule :C15H28N4O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :328.41Coenzyme A Trilithium Salt
CAS :<p>Stability Hygroscopic<br>Applications A cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.<br>References Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010); Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968);<br></p>Formule :C21H33N7O16P3S·3LiCouleur et forme :NeatMasse moléculaire :785.33Ribavirin-13C5
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled Ribavirin (R414475). Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Formule :C5C3H12N4O5Couleur et forme :NeatMasse moléculaire :249.17N-Carbamoyl-2-fluoro-(β)-alanine
CAS :Produit contrôlé<p>Applications A metabolite of Capecitabine.<br>References Arellano, M., ET AL.: Br. J. Cancer, 77, 79 (1998), Budman, D., ET AL.: J. Clin. Oncol., 16, 1795 (1998), Khanna, R., et al.: Cancer Res., 60, 4725 (2000), Charasson, V., et al.: Drug Metab. Dispos., 30, 731 (2002),<br></p>Formule :C4H7FN2O3Couleur et forme :NeatMasse moléculaire :150.116,6'-Thiobis-9H-purine
CAS :Produit contrôlé<p>Applications 6,6'-Thiobis-9H-purine is used in the study of the activity of topoisomerase IIα.<br>References Jensen, L.H., et al.: Molecular Pharmacology, 70, 1503 (2006);<br></p>Formule :C10H6N8SCouleur et forme :NeatMasse moléculaire :270.27Adenosine-1'-13C
CAS :Produit contrôléFormule :CC9H13N5O4Couleur et forme :White To Off-WhiteMasse moléculaire :268.234Adenosine 5'-Triphosphate Disodium Salt
CAS :<p>Stability Hygroscopic, Temperature Sensitive<br>Applications A metabolite of Adenosine (A280400), a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism.<br>References Knowles, J., et al.: Annu. Rev. Biochem., 49, 877 (1980),<br></p>Formule :C10H14N5O13P3·2NaCouleur et forme :NeatMasse moléculaire :569.162’-Deoxy Cytidine-5,6-d2
CAS :Produit contrôléFormule :C9D2H11N3O4Couleur et forme :NeatMasse moléculaire :229.23Hypoxanthine
CAS :Produit contrôlé<p>Applications A naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine Chemicals<br>References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),<br></p>Formule :C5H4N4OCouleur et forme :NeatMasse moléculaire :136.11Ademethionine 1,4-Butanedisulfonate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.<br></p>Formule :C15H22N6O5S·3C4H10O6S2Couleur et forme :NeatMasse moléculaire :1451.62epi-Canagliflozin
CAS :Produit contrôlé<p>Applications epi-Canagliflozin is an epimeric impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity.<br>References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);<br></p>Formule :C24H25FO5SCouleur et forme :NeatMasse moléculaire :444.52(1R,2R,5R)-2-Isopropyl-5-methylcyclohexanol
CAS :<p>Applications (1R,2R,5R)-2-Isopropyl-5-methylcyclohexanol is used in the tetrahydropyranylation of alcohols.<br>References Magyar, A. et al.: Catal. Lett., 145, 1876 (2015);<br></p>Formule :C10H20OCouleur et forme :NeatMasse moléculaire :156.275-Chlorocytidine
CAS :Produit contrôléFormule :C9H12ClN3O5Couleur et forme :NeatMasse moléculaire :277.66
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