Peptides

<p>Applications Cyclo(Leu-Gly) is an antimicrobial compound produced by Latobacillus plantarum.<br>References Niku-Paavola, M., et al.: J. Appl. Microbiol., 86, 29 (1999)<br></p>

<p>Applications N-L-GAMMA-GLUTAMYL-L-LEUCINE (cas# 2566-39-4) is a useful research chemical.<br></p>

<p>Applications H-GLU-LYS-OH (cas# 5891-53-2) is a useful research chemical.<br></p>

<p>Applications Antibiotic substance belonging to the actinomycin complex, produced by several Streptomyces spp. Antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Manaker, et al.: Antibiot. Ann., 55, 853 (1954), Jain, S., et al.: J. Mol. Biol., 114, 317 (1977), Nakajima, K., et al.: Pept. Chem., 19, 143 (1981), Shereda, R., et al.: J. Biol. Chem., 282, 19247 (2007),<br></p>

<p>Stability Hygroscopic<br>Applications MG 132 is a potent, membrane-permeable proteasome inhibitor. It induces neurite outgrowth in PC12 cells. Neuroprotective product.<br>References Lee, D., et al.: Trends in Cell Biol., 8, 397 (1998); Tsubuki, S., et al.: J. Biochem., 119., 572 (1996); Grimm, L., et al.: EMBO J., 15, 3835 (1996)<br></p>

<p>Applications Benzotriazol-1-yl-oxytripyrrolidinphosphonium Hexafluorophosphate (cas# 128625-52-5) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).<br>References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);<br></p>

<p>Applications L-Carnosine is a naturally-occurring histidine-containing compound and the biological role of this dipeptide is to act as cytosolic buffering agents. Other roles ascribed to L-Carnosine include actions as neurotransmitters, modulation of enzymic activities and chelation of heavy metals.<br>References Quinn, P.J., et al.: Mol. Aspects. Med., 13, 379 (1992); Aruoma, O.I., et al.: Biochem. J., 264, 863 (1989);<br></p>

<p>Applications DOTA-tris (t-Bu ester), is a Bifunctional chelator, that can be used in the preparation of gadolinium complexes as MRI blood contrast agents.<br></p>

<p>Applications 1-Azido-3,6,9-trioxaundecane-11-ol (cas# 86770-67-4) is a compound useful in organic synthesis.<br>References Hatch, D., et al.: ChemBioChem., 9, 2433 (2008),<br></p>

<p>Applications Poly(ethylene Glycol) molecules of an average molecular mass of 6000. Poly(ethylene Glycol) is used in various applications from industrial chemistry to biological chemistry. Recent research has shown PEG maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals. In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery. It is industrially produced as a lubricating substance for various surfaces to reduce friction. PEG is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.<br>References Borgens, R. et al.: J. Neurosci. Res., 66, 1179 (2001); Stavisky, R. et al.: Neurosci. Lett., 376, 98 (2005); Nalam, P. et al.: Tribiol. Lett., 37, 541 (2010); Steinmetz, N. et al.: J. Am. Chem. Soc., 131, 17093 (2009); Li, X. et al.: J. Am. Chem. Soc., 133, 11147 (2011); Li, L. et al.: Int. J. Pharm., 447, 192 (2013)<br></p>

<p>Applications N-tert-Boc-L-alanine is the protected form of L-Alanine (A481500), a non-essential amino acid that can be found naturally in the human body and is obtained by our diet.<br>References Anderson, H., et al.: J. Nutr., 99, 82 (1969)<br></p>

<p>Applications An obstetric drug used to control postpartum hemorrhaging.<br>References Sanz-Nebot, V., et al.: Anal. Bioanal. Chem., 377, 306 (2003), Gimpl, G., et al.: Eur. J. Pharmacol., 510, 9 (2005), Handler, J., et al.: Theriogenol., 66, 1397 (2006), Klenerova, V., et al.: J. Physiol. Pharmacol., 60, 57 (2009),<br></p>

Melittin: principal bee venom toxin, 26 amino acids, activates low-weight PLA2, not high-weight PLA2.

<p>Applications DAPT is a γ-secretase inhibitor which inhibits thegrowth of cancer cells and epethelial and mesenchymal transition (1,2).<br>References (1) Li, L. et al.: Oncol Lett. 7, 2160 (2014) (2) Wang, M. et al.: Int. J. Onc., 44, 1401 (2014)<br></p>

<p>Applications H-GAMMA-GLU-GLU-OH (cas# 1116-22-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications Doxorubicin Hydrochloride is an antineoplastic agent.<br>References Di Marco, A., et al.: Cancer Chemother. Rep., (part 1), 53, 33 (1969); Mihich, E. and Ehrke, M.J.: Transplant. Proc., 16, 499 (1984);<br></p>

<p>Stability Hygroscopic<br>Applications Fructosyl Glycine is a synthetic glycoamine used in the study of glycoamine analogs and their effect on metastatic carcinoma cells.<br>References Glinsky, G. et al.: Clin. Exp. Metastas., 14, 253 (1996);<br></p>