CAS: 1028486-01-2 - 4-{[9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acid

Formula: C₂₇H₂₀ClFN₄O₄

InChI: InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11,13H,12H2,1-2H3,(H,34,35)(H,31,32,33)

InChI key: InChIKey=ZLHFILGSQDJULK-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=C(C=C1OC)NC=2N=CC3=C(N2)C=4C=CC(Cl)=CC4C(=NC3)C=5C(F)=CC=CC5OC

Sinonimi:

• Alisertib
• Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-
• Mln 8237

4-((9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-yl)amino)-2-methoxybenzoic acid

CAS: 1028486-01-2

• Formula: C₂₇H₂₀ClFN₄O₄
• Purezza: 98%
• Colore e forma: Solid
• Peso molecolare: 518.9235

MLN 8237

CAS: 1028486-01-2

Alisertib

CAS: 1028486-01-2

Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of …

• Formula: C₂₇H₂₀ClFN₄O₄
• Purezza: 100% - 99.82%
• Colore e forma: Solid
• Peso molecolare: 518.92

MLN 8237 (Contain 10% DMSO)

CAS: 1028486-01-2

Applications An Aurora kinase inhibitor, used to treat patients with advanced solid tumors.

• Formula: C₂₇H₂₀ClFN₄O₄
• Colore e forma: Neat
• Peso molecolare: 518.9235

MLN 8237

CAS: 1028486-01-2

Antagonist of Aurora A serine/threonine protein kinase; antineoplastic

• Formula: C₂₇H₂₀ClFN₄O₄
• Purezza: Min. 95%
• Colore e forma: Powder
• Peso molecolare: 518.92 g/mol