Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(163 prodotti)
- Bcr-Abl(117 prodotti)
- EGFR(591 prodotti)
- FAK(72 prodotti)
- FLT(91 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(183 prodotti)
- JAK(246 prodotti)
- PDGFR(128 prodotti)
- RAAS(90 prodotti)
- Src(82 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(246 prodotti)
Mostrare 6 più sottocategorie
Trovati 2175 prodotti di "Angiogenesi"
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2,3-Naphthalic Anhydride
CAS:Prodotto controllato<p>Stability Moisture Sensitive<br>Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.<br>References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)<br></p>Formula:C12H6O3Colore e forma:NeatPeso molecolare:198.17Pulsatilla Saponin D (90%)
CAS:Prodotto controllato<p>Applications Pulsatilla Saponin D shows antiangiogenic and antitumor activity.<br>References Sang-Won, H. et al.: Carcinogen., 34, 2156 (2013);<br></p>Formula:C47H76O17Purezza:90%Colore e forma:NeatPeso molecolare:913.1Atrasentan
CAS:Prodotto controllato<p>Applications Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.<br>References Bax, W., et al.: Trends Pharmacol. Sci., 15, 379 (1994); Winn, M., et al.: J. Med. Chem., 39, 1039 (1996); Wu-Wong, J., et al.: J. Pharmacol. Exp. Ther., 281, 791 (1997);<br></p>Formula:C29H38N2O6Colore e forma:Off-WhitePeso molecolare:510.622-Chloro-N-[4-(1-cyanocyclopentyl)phenyl]-3-pyridinecarboxamide
CAS:Prodotto controllato<p>Applications 2-Chloro-N-[4-(1-cyanocyclopentyl)phenyl]-3-pyridinecarboxamide is an intermediate Apatinib 25-N-Oxide (A726160), a metabolite of the antiangiogenic agent and selective VEGFR2 inhibitor Apatinib (A726150).<br></p>Formula:C18H16ClN3OColore e forma:NeatPeso molecolare:325.79Dehydrodivanillin (~90%, contains up to 10% unknown inorganics)
CAS:Formula:C16H14O6Colore e forma:NeatPeso molecolare:302.279LB 42708
CAS:Prodotto controllato<p>Applications LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors.<br>References Kim, C., et. al.: Mol. Pharmacol., 78, 142 (2010)<br></p>Formula:C30H27BrN4O2Colore e forma:NeatPeso molecolare:555.464-Fmoc-3(R)-morpholinecarboxylic Acid
CAS:Prodotto controllato<p>Applications 4-Fmoc-3(R)-morpholinecarboxylic Acid is used to prepare 125I-labeled morpholine-containing RGD ligand of αvβ3 integrin as angiogenesis imaging probe.<br>References Bianchini, F., et al.: J. Med. Chem., 55, 5024 (2012)<br></p>Formula:C20H19NO5Colore e forma:NeatPeso molecolare:353.37Tyrphostin AG 112
CAS:Prodotto controllato<p>Applications Tyrphostin AG 112 is an EGFR inhibitor.<br></p>Formula:C13H8N4OColore e forma:NeatPeso molecolare:236.23N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine
CAS:Prodotto controllatoFormula:C20H16FN5O3Colore e forma:Light Yellow To YellowPeso molecolare:393.37E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purezza:99.52%Colore e forma:SolidPeso molecolare:378.46Bucillamine
CAS:Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.Formula:C7H13NO3S2Purezza:99.47%Colore e forma:SolidPeso molecolare:223.31SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formula:C28H30ClN5O4SPurezza:98.62% - 99.53%Colore e forma:Orange PowderPeso molecolare:568.09Ref: TM-T6154
1mg47,00€2mg59,00€5mg97,00€10mg150,00€25mg283,00€50mg465,00€100mg688,00€1mL*10mM (DMSO)150,00€GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Formula:C22H18F3N3O4SPurezza:99.92%Colore e forma:SolidPeso molecolare:477.46CP-547632
CAS:CP-547632 is an oral ATP-competitive inhibitor of VEGFR-2/FGF kinase with IC50s of 11/9 nM, highly selective, has antitumor activity.Formula:C20H24BrF2N5O3SPurezza:99.14%Colore e forma:SolidPeso molecolare:532.4Icotinib Hydrochloride
CAS:Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.Formula:C22H22ClN3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:427.88TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purezza:99.73%Colore e forma:SolidPeso molecolare:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€Jaspamycin
CAS:Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Formula:C12H12N4O5Colore e forma:SolidPeso molecolare:292.25OD36
CAS:OD36: Potent RIPK2 inhibitor, IC50=5.3 nM; hinders ALK2 signaling and osteogenesis, KD=37 nM; targets ALK2 ATP pocket.Formula:C16H15ClN4O2Purezza:99.45%Colore e forma:SolidPeso molecolare:330.77FLT3-IN-11
CAS:FLT3-IN-11, an oral FLT3 kinase inhibitor: potent, selective, IC50 - wild-type 7.22 nM, FLT3-D835Y 4.95 nM, anti-AML IC50 3.2 nM for MV4-11.Formula:C20H25F3N6OColore e forma:SolidPeso molecolare:422.45ZK-261991
CAS:ZK-261991 is an orally active inhibitor of VEGFR tyrosine kinase(IC50 of 5 nM, VEGFR2).Formula:C24H25N7O2Purezza:98%Colore e forma:SolidPeso molecolare:443.5
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