Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(165 prodotti)
- Bcr-Abl(117 prodotti)
- EGFR(561 prodotti)
- FAK(72 prodotti)
- FLT(89 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(177 prodotti)
- JAK(243 prodotti)
- PDGFR(127 prodotti)
- RAAS(86 prodotti)
- Src(82 prodotti)
- Syk(37 prodotti)
- Trombina(51 prodotti)
- VDA(2 prodotti)
- VEGFR(239 prodotti)
Mostrare 6 più sottocategorie
Trovati 2260 prodotti di "Angiogenesi"
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NVP-BSK805
CAS:NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Formula:C27H28F2N6OPurezza:98%Colore e forma:SolidPeso molecolare:490.55BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purezza:99.08%Colore e forma:SolidPeso molecolare:368.43BIBF 1202
CAS:BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).Formula:C30H31N5O4Purezza:98.04%Colore e forma:SolidPeso molecolare:525.6Naquotinib mesylate
CAS:Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of 8-33 nM and 230 nM for toward EGFRFormula:C31H46N8O6SPurezza:98%Colore e forma:SolidPeso molecolare:658.81Almonertinib hydrochloride
CAS:Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.Formula:C30H36ClN7O2Purezza:98.01% - 98.12%Colore e forma:SolidPeso molecolare:562.1(Rac)-SAR131675
CAS:(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.Formula:C18H22N4O4Purezza:98.73% - 99.1%Colore e forma:SolidPeso molecolare:358.39Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purezza:99.46% - 99.66%Colore e forma:SolidPeso molecolare:441.46Canertinib dihydrochloride
CAS:Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic andFormula:C24H27Cl3FN5O3Purezza:99.13% - >99.99%Colore e forma:SolidPeso molecolare:558.86Behenamide
CAS:Prodotto controllatoApplications Behenamide is a fatty acid amide as an angiogenic. The mechanism of angiogenic activity is unknown and this lipid does not promote proliferation of endothelial cells or induce inflammatory effects.
References Wakamatsu, K., et al.: Biochem. Biophysical Res. Comm., 168, 423 (1990),Formula:C22H45NOColore e forma:White To Off-WhitePeso molecolare:339.6(5E)-5-(4-Hydroxybenzylidene)-1,3-thiazolidine-2,4-dione
CAS:Prodotto controllatoApplications 5-[(4-Hydroxyphenyl)methylene]-2,4-thiazolidinedione is a 5-Benzylidene-2,4-thiazolidenedione derivative designed as inhibitors of angiogenesis targeting VEGFR-2. Also, it is an intermediate used in the synthesis of MSDC 0602 (M755420), which is an analogue of thiazolidinediones, exhibits low affinity for binding and activation of peroxisome proliferator-activated receptor γ (PPARγ). Thiazolidinediones are effective insulin-sensitizing drugs for treating various metabolic and inflammatory diseases.
References Bhanushali, U., et al.: Bioorg. Chem., 67, 139-147 (2016); Chen, Z., et al.: J. Biol. Chem. 287, 23537 (2012); Fukunaga, T., et al.: J. Bone Miner. Res., 30, 508 (2015)Formula:C10H7NO3SColore e forma:NeatPeso molecolare:221.23Methyl 6-[[[(2-Chloroethyl)amino]carbonyl]amino]-6-deoxy-Alpha-D-glucopyranoside
CAS:Prodotto controllatoFormula:C10H19ClN2O6Colore e forma:NeatPeso molecolare:298.72Serclutamab
CAS:Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR).
Purezza:98%Colore e forma:LiquidSolrikitug
CAS:Solrikitug,Anti-CRLF2 humanized IgG1κ monoclonal antibody.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDaDepatuxizumab
CAS:Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, inhibit tumor growth,GBM,SCCHN.Purezza:95%Colore e forma:LiquidFidasimtamab
CAS:Fidasimtamab, a recombinant human IgG1 bispecific antibody, targets both HER2 and PD-1, bridging T cells and tumor cells to modulate immune responses.Purezza:95% - 98.0% (SDS-PAGE); 98.3% (SEC-HPLC)Colore e forma:LiquidEGFR T790M/L858R-IN-8
CAS:EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.Formula:C16H11BrN2O3Colore e forma:SolidPeso molecolare:359.17Izalontamab
CAS:Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.Purezza:95%+ - 95.3% (SDS-PAGE); 99.2% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:197.21 kDaAnti-Mouse VEGFR-2 Antibody (DC101)
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.Purezza:99%Colore e forma:LiquidPeso molecolare:150 kDaIvonescimab
CAS:Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, NSCLC).Purezza:95% - >95.0% (SDS-PAGE); 98.99% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:201.12 kDaImgatuzumab
CAS:Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.
Colore e forma:LiquidPeso molecolare:145.0 (kDa)
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