Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(158 prodotti)
- Bcr-Abl(113 prodotti)
- EGFR(598 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(182 prodotti)
- JAK(246 prodotti)
- PDGFR(126 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(250 prodotti)
Mostrare 6 più sottocategorie
Trovati 2040 prodotti di "Angiogenesi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
A-443654
CAS:A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formula:C24H23N5OPurezza:98.04% - 99.51%Colore e forma:SolidPeso molecolare:397.47Gusacitinib HCl
CAS:<p>Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.</p>Formula:C24H29ClN8O2Colore e forma:SolidPeso molecolare:497HG-14-10-04
CAS:<p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>Formula:C29H34ClN7OPurezza:99.75% - >99.99%Colore e forma:SolidPeso molecolare:532.08UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formula:C19H25ClN8Purezza:99.52%Colore e forma:SolidPeso molecolare:400.91FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purezza:97.63% - 98.92%Colore e forma:SolidPeso molecolare:691.61NVP-BHG712
CAS:NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormula:C26H20F3N7OPurezza:97.32% - 98.63%Colore e forma:SolidPeso molecolare:503.48JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purezza:99.41% - 99.97%Colore e forma:SolidPeso molecolare:466.33Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purezza:99.43% - 99.67%Colore e forma:SolidPeso molecolare:431.53Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formula:C30H35N7O2Purezza:99.99%Colore e forma:SolidPeso molecolare:525.64Alflutinib mesylate
CAS:Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.Formula:C29H35F3N8O5SPurezza:97.94% - 99.63%Colore e forma:SolidPeso molecolare:664.7Oritinib mesylate
CAS:Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.Formula:C32H41N7O5SColore e forma:SolidPeso molecolare:635.78Lapatinib tosylate
CAS:Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Formula:C36H34ClFN4O7S2Colore e forma:SolidPeso molecolare:753.26BIIB068
CAS:BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formula:C23H29N7O2Purezza:97.98%Colore e forma:SolidPeso molecolare:435.52Vactosertib
CAS:Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formula:C22H18FN7Purezza:98.85% - 99.81%Colore e forma:SolidPeso molecolare:399.42(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurezza:99.24%Colore e forma:SolidPeso molecolare:386.45Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purezza:96.17% - 99.85%Colore e forma:SolidPeso molecolare:557.04Tucatinib
CAS:Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Formula:C26H24N8O2Purezza:99.05% - 99.96%Colore e forma:SolidPeso molecolare:480.52Larotinib mesylate hydrate
CAS:Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nMFormula:C26H36ClFN4O11S2Colore e forma:SolidPeso molecolare:699.17Crizotinib acetate
CAS:Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.Formula:C23H26Cl2FN5O3Colore e forma:SolidPeso molecolare:510.39DGY-06-116
CAS:DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.Formula:C32H33ClN8O2Purezza:97.65%Colore e forma:SolidPeso molecolare:597.11Brigatinib
CAS:<p>Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.</p>Formula:C29H39ClN7O2PPurezza:97.18% - >99.99%Colore e forma:SolidPeso molecolare:584.09WHI-P180 hydrochloride
CAS:WHI-P180 (Janex 3) inhibits RET, KDR and EGFR with IC50 values of 5 nM, 66 nM and 4 μM, respectively. WHI-P180 is a multi-kinase inhibitor.Formula:C16H16ClN3O3Colore e forma:SolidPeso molecolare:333.77Syk Inhibitor II dihydrochloride dihydrate
CAS:Potent, selective ATP-competitive Syk Inhibitor II (IC50: 41 nM), with anti-allergic properties, in dihydrochloride dihydrate form.Formula:C14H21Cl2F3N6O3Colore e forma:SolidPeso molecolare:449.26RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurezza:99.56%Colore e forma:SolidPeso molecolare:518.41SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormula:C32H40ClF2N6O13PPurezza:98.07%Colore e forma:SolidPeso molecolare:821.12Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Formula:C21H21FN6OPurezza:99.35% - 99.92%Colore e forma:SolidPeso molecolare:392.43BMS-536924
CAS:BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormula:C25H26ClN5O3Purezza:99.02%Colore e forma:SolidPeso molecolare:479.96Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurezza:98.74% - 99.49%Colore e forma:SolidPeso molecolare:445.54PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formula:C18H24N6OPurezza:99.98%Colore e forma:SolidPeso molecolare:340.42PF-562271 besylate
CAS:PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formula:C21H20F3N7O3S·C6H6O3SPurezza:97.65% - 99.01%Colore e forma:SolidPeso molecolare:665.66WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purezza:99.21%Colore e forma:SolidPeso molecolare:297.31Onatasertib
CAS:Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formula:C21H27N5O3Purezza:99.14% - 99.93%Colore e forma:SolidPeso molecolare:397.47(Rac)-JBJ-04-125-02
CAS:(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.Formula:C29H26FN5O3SPurezza:97.57%Colore e forma:SolidPeso molecolare:543.61CGP77675 hydrate
CGP77675 hydrate: Oral Src family kinase inhibitor with IC50s of 5-20/40 nM (Src auto/phosphorylation) and has anticancer properties.Colore e forma:SolidTAS0728
CAS:TAS0728 is a HER2 inhibitor, with antitumor activityFormula:C26H32N8O3Purezza:97.78%Colore e forma:SolidPeso molecolare:504.58Tyrphostin AG 528
CAS:Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).Formula:C18H14N2O3Purezza:99.64%Colore e forma:SolidPeso molecolare:306.32Tolimidone
CAS:<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Formula:C11H10N2O2Purezza:99.85% - 99.85%Colore e forma:SolidPeso molecolare:202.21Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurezza:99.38% - >99.99%Colore e forma:SolidPeso molecolare:447.51Afatinib oxalate
CAS:Afatinib oxalate (BIBW 2992) is an irreversible ErbB inhibitor, treating ESCC, NSCLC, and gastric cancer. Targets EGFRwt, EGFRL858R/T790M, HER2.Formula:C28H29ClFN5O11Colore e forma:SolidPeso molecolare:666.01JCN037
CAS:JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Formula:C16H11BrFN3O2Purezza:99.5%Colore e forma:SolidPeso molecolare:376.18NRC-2694
CAS:NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.Formula:C24H26N4O3Purezza:99.90%Colore e forma:SolidPeso molecolare:418.49Vatalanib succinate
CAS:Vatalanib succinate is a VEGFR, PDGFR-β, c-Kit, c-Fms, and aromatase inhibitor.Formula:C24H21ClN4O4Colore e forma:SolidPeso molecolare:464.91VEGFR2-IN-2
CAS:VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Formula:C15H11BrN2OPurezza:99.504%Colore e forma:SolidPeso molecolare:315.16Acriflavine Hydrochloride
CAS:Acriflavine HCl is a HIF-1α inhibitor reducing PGK1, VEGF, and HIF-1α levels both in vitro and in vivo.Formula:C14H14ClN3Purezza:99.8%Colore e forma:SolidPeso molecolare:259.73Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurezza:96.13% - 99.09%Colore e forma:SolidPeso molecolare:624.42Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purezza:99.54% - 99.77%Colore e forma:SolidPeso molecolare:482.51Erdafitinib
CAS:Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formula:C25H30N6O2Purezza:97.00% - 99.36%Colore e forma:SolidPeso molecolare:446.54SU5408
CAS:SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.Formula:C18H18N2O3Purezza:99.35%Colore e forma:SolidPeso molecolare:310.35Trastuzumab
CAS:Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Purezza:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Colore e forma:LiquidPeso molecolare:Approximately 145.53 kDaPelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formula:C24H23ClFN5O2Purezza:98.37% - 99.84%Colore e forma:Off-White SolidPeso molecolare:467.92Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Formula:C27H21F3N8OPurezza:99.13% - 99.97%Colore e forma:SolidPeso molecolare:530.5PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formula:C32H36N8O3Purezza:97.16% - 98.12%Colore e forma:SolidPeso molecolare:580.68Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purezza:98.52% - >99.99%Colore e forma:SolidPeso molecolare:425.46Vandetanib hydrochloride
CAS:Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).Formula:C22H25BrClFN4O2Colore e forma:SolidPeso molecolare:511.81CNX-774
CAS:CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).Formula:C26H22FN7O3Purezza:97.35% - 99.11%Colore e forma:SolidPeso molecolare:499.5Nastorazepide
CAS:Nastorazepide is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.Formula:C29H36N4O5Purezza:99.83%Colore e forma:SolidPeso molecolare:520.62CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purezza:99.35% - 99.88%Colore e forma:SolidPeso molecolare:491.5Vadimezan
CAS:Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity.Formula:C17H14O4Purezza:97.38% - 99.8%Colore e forma:SolidPeso molecolare:282.29Coumarin-3-carboxylic acid
CAS:<p>The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/</p>Formula:C10H6O4Purezza:99.88%Colore e forma:Light Brown Crystalline PowderPeso molecolare:190.15Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formula:C22H19ClN4O5Purezza:98.08% - 99.67%Colore e forma:SolidPeso molecolare:454.86Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurezza:98.01%Colore e forma:SolidPeso molecolare:244.29Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Formula:C26H21F3N4O4Purezza:99.67% - 99.75%Colore e forma:SolidPeso molecolare:510.46RO8191
CAS:RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formula:C14H5F6N5OPurezza:98% - 98.85%Colore e forma:SolidPeso molecolare:373.212-(1,8-naphthyridin-2-yl)phenol
CAS:2-NP is a STAT1 enhancer.Formula:C14H10N2OPurezza:99.33% - 99.82%Colore e forma:SolidPeso molecolare:222.24Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purezza:99.45% - ≥98%Colore e forma:White SolidPeso molecolare:562.7Desmethylanethol trithione
CAS:<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Formula:C9H6OS3Purezza:98.05% - 98.41%Colore e forma:SolidPeso molecolare:226.34EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurezza:98.99% - >99.99%Colore e forma:SolidPeso molecolare:430.55(S)-Afatinib
CAS:(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formula:C24H25ClFN5O3Purezza:99.22% - >99.99%Colore e forma:Off-White SolidPeso molecolare:485.94R-268712
CAS:R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formula:C20H18FN5OPurezza:99.61%Colore e forma:SolidPeso molecolare:363.392,4-DPD
CAS:<p>2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)</p>Formula:C11H13NO4Purezza:99.74%Colore e forma:Yellow Solid CrystallinePeso molecolare:223.23MELK-8a
CAS:MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formula:C25H32N6OColore e forma:SolidPeso molecolare:432.56Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purezza:99.80%Colore e forma:SolidPeso molecolare:542.03CNX-2006
CAS:CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Formula:C26H27F4N7O2Purezza:98.85% - 99.16%Colore e forma:SolidPeso molecolare:545.53RG13022
CAS:RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Formula:C16H14N2O2Purezza:98.38%Colore e forma:SolidPeso molecolare:266.29A-419259
CAS:A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.Formula:C29H34N6OPurezza:99.48%Colore e forma:SolidPeso molecolare:482.62Tropisetron
CAS:Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Formula:C17H20N2O2Purezza:99.68%Colore e forma:White SolidPeso molecolare:284.35PD158780
CAS:PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Formula:C14H12BrN5Purezza:98.81%Colore e forma:SolidPeso molecolare:330.181-NM-PP1
CAS:1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.Formula:C20H21N5Purezza:98% - 98.93%Colore e forma:White Cyrstalline SolidPeso molecolare:331.41Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFormula:C24H27ClFN5O3Purezza:99.52%Colore e forma:SolidPeso molecolare:487.96Olmutinib hydrochloride
CAS:Olmutinib is a third-gen EGFR inhibitor for T790M-positive lung cancer, blocking phosphorylation and tumor pathways. Approved in Korea (2016).Formula:C26H28Cl2N6O2SColore e forma:SolidPeso molecolare:559.51EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)Formula:C23H21N3O3Purezza:99.55%Colore e forma:SolidPeso molecolare:387.43Silymarin
CAS:Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.Formula:C25H22O10Purezza:98%Colore e forma:Yellow And Brown PowderPeso molecolare:482.44PP 3
CAS:<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Formula:C11H9N5Purezza:98.61%Colore e forma:Whit To Off-White SolidPeso molecolare:211.224SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Formula:C33H38N8O4SPurezza:96.4% - 99.67%Colore e forma:SolidPeso molecolare:642.775-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formula:C12H9N3SPurezza:97%Colore e forma:SolidPeso molecolare:227.29SB-505124
CAS:SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.Formula:C20H21N3O2Purezza:97.19% - 99.92%Colore e forma:SolidPeso molecolare:335.4Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formula:C26H27FN10Purezza:96.59% - 99.7%Colore e forma:SolidPeso molecolare:498.56Momelotinib HCl
CAS:<p>Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.</p>Formula:C23H24Cl2N6O2Colore e forma:SolidPeso molecolare:487.38Oglufanide
CAS:<p>Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).</p>Formula:C16H19N3O5Purezza:99.80%Colore e forma:SolidPeso molecolare:333.34squarunkinA
CAS:squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Formula:C25H32F3N5O4Purezza:99.29%Colore e forma:SolidPeso molecolare:523.55AC1NS4RE
CAS:It is a tyrosine kinase inhibitor.Formula:C15H13ClN2OPurezza:99.53%Colore e forma:SolidPeso molecolare:272.73PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurezza:99.92%Colore e forma:SolidPeso molecolare:532.51Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purezza:99.25% - 99.49%Colore e forma:SolidPeso molecolare:472.58Spebrutinib
CAS:Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplasticFormula:C22H22FN5O3Purezza:97.02% - >99.99%Colore e forma:SolidPeso molecolare:423.44SM 16
CAS:SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).Formula:C25H26N4O3Purezza:99.72%Colore e forma:SolidPeso molecolare:430.5CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formula:C17H16FN5Purezza:99.29%Colore e forma:SolidPeso molecolare:309.34SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Formula:C16H13NO2Purezza:99.45% - 99.55%Colore e forma:SolidPeso molecolare:251.28WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Formula:C24H25ClN6O2Purezza:97.15%Colore e forma:SolidPeso molecolare:464.95Entrectinib
CAS:Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C31H34F2N6O2Purezza:98.03% - 99.61%Colore e forma:SolidPeso molecolare:560.64Arnebin 1
CAS:<p>(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.</p>Formula:C21H22O6Purezza:98.76% - 99.81%Colore e forma:SolidPeso molecolare:370.396Merestinib dihydrochloride
CAS:Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formula:C30H24Cl2F2N6O3Colore e forma:SolidPeso molecolare:625.45A-176120
CAS:A-176120: potent FPP analog, inhibits farnesyltransferase, anti-angiogenic, may curb H-ras NIH3T3 tumor growth.Formula:C33H29NO9Colore e forma:SolidPeso molecolare:583.58Syk Inhibitor II dihydrochloride
CAS:Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formula:C14H17Cl2F3N6OPurezza:98.53%Colore e forma:SolidPeso molecolare:413.22GluR6 antagonist-1
CAS:GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formula:C15H11ClN2OSPurezza:99.89%Colore e forma:SolidPeso molecolare:302.78Alofanib
CAS:Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.Formula:C19H15N3O6SPurezza:99.53% - 99.81%Colore e forma:SolidPeso molecolare:413.41-Naphthyl PP1 hydrochloride
CAS:1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormula:C19H20ClN5Purezza:98.63%Colore e forma:SolidPeso molecolare:353.85Adaphostin
CAS:Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formula:C24H27NO4Purezza:98.29%Colore e forma:SolidPeso molecolare:393.48UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.Formula:C28H42Cl2N6OPurezza:99.71%Colore e forma:SolidPeso molecolare:549.62Ribociclib
CAS:Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).Formula:C23H30N8OPurezza:97.91% - >99.99%Colore e forma:SolidPeso molecolare:434.54AKN-028 trifluoroacetate
CAS:AKN-028 trifluoroacetate causes cell cycle arrest and lowers Myc genes and tyrosine kinase activity in AML.Formula:C19H15F3N6O2Colore e forma:SolidPeso molecolare:416.36(Z)-SU4312
CAS:<p>(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).</p>Formula:C17H16N2OPurezza:99.17%Colore e forma:SolidPeso molecolare:264.321-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formula:C19H19N5Purezza:99.85%Colore e forma:White Cyrstalline SolidPeso molecolare:317.39Gefitinib dihydrochloride
CAS:Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.Formula:C22H26Cl3FN4O3Colore e forma:SolidPeso molecolare:519.82WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purezza:99.66% - 99.92%Colore e forma:SolidPeso molecolare:281.31PP1
CAS:PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Formula:C16H19N5Purezza:99% - 99.88%Colore e forma:Off-White To Grey SolidPeso molecolare:281.36Nazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Formula:C26H31ClN6O2Purezza:98.63% - ≥95%Colore e forma:Solid PowderPeso molecolare:495.02Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purezza:98.40% - 99.73%Colore e forma:SolidPeso molecolare:443.54E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurezza:99.31% - 99.87%Colore e forma:SolidPeso molecolare:474.44Desmethyl Erlotinib
CAS:Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).Formula:C21H21N3O4Purezza:97.92% - 98.62%Colore e forma:SolidPeso molecolare:379.41Quizartinib HCl
CAS:Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.Formula:C29H34Cl2N6O4SColore e forma:SolidPeso molecolare:633.59Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formula:C23H26FN5O3Purezza:97.35%Colore e forma:SolidPeso molecolare:439.48WS6
CAS:WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Formula:C29H31F3N6O3Purezza:97.65% - 99.95%Colore e forma:SolidPeso molecolare:568.597BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Formula:C16H10BrN3O2Purezza:99.67%Colore e forma:SolidPeso molecolare:356.17NS309
CAS:NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Formula:C8H4Cl2N2O2Purezza:97.55%Colore e forma:SolidPeso molecolare:231.04Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Colore e forma:SolidPeso molecolare:356.43CHMFL-BMX-078
CAS:CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.Formula:C33H35N7O6Purezza:>99.99%Colore e forma:SolidPeso molecolare:625.67Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purezza:98.56% - 99.9%Colore e forma:Off-White SolidPeso molecolare:485.94Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purezza:97.51% - 98.75%Colore e forma:Orange SolidPeso molecolare:412.48(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formula:C29H32N4O8Colore e forma:SolidPeso molecolare:564.59JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purezza:97.08%Colore e forma:SolidPeso molecolare:364.79GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purezza:99.75%Colore e forma:SolidPeso molecolare:612.03NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formula:C24H27ClN4O3Colore e forma:SolidPeso molecolare:454.95SB-431542
CAS:SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.Formula:C22H16N4O3Purezza:99.035% - >99.99%Colore e forma:SolidPeso molecolare:384.39Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formula:C29H34N6O4S2Purezza:97.67% - 98.44%Colore e forma:SolidPeso molecolare:594.75(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:360SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purezza:98.13%Colore e forma:SolidPeso molecolare:442.48PF-573228
CAS:PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.Formula:C22H20F3N5O3SPurezza:96.58% - 99.51%Colore e forma:SolidPeso molecolare:491.49NVP-BSK805 trihydrochloride
CAS:NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.Formula:C27H31Cl3F2N6OColore e forma:SolidPeso molecolare:599.93CCT196969
CAS:CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.Formula:C27H24FN7O3Purezza:98.93% - 99.65%Colore e forma:SolidPeso molecolare:513.52A 77-01
CAS:A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.Formula:C18H14N4Purezza:98.82% - ≥95%Colore e forma:SolidPeso molecolare:286.33Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Formula:C10H7NO4Purezza:99.02%Colore e forma:SolidPeso molecolare:205.17Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purezza:98.20% - 99.36%Colore e forma:White To Off-White SolidPeso molecolare:459.9SKLB4771
CAS:<p>SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.</p>Formula:C25H27N7O3S2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:537.66AG1557
CAS:<p>AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).</p>Formula:C16H14IN3O2Purezza:98.61% - 99.23%Colore e forma:SolidPeso molecolare:407.21Saracatinib difumarate
CAS:Saracatinib difumarate is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities.Formula:C35H40ClN5O13Colore e forma:SolidPeso molecolare:774.18Mobocertinib
CAS:Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agentFormula:C32H39N7O4Purezza:99.47% - 99.97%Colore e forma:SolidPeso molecolare:585.7RepSox
CAS:RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).Formula:C17H13N5Purezza:98.8% - 99.73%Colore e forma:SolidPeso molecolare:287.32Canertinib
CAS:Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.Formula:C24H25ClFN5O3Purezza:98% - >99.99%Colore e forma:White Or Similar To White Crystalline PowderPeso molecolare:485.94ZM323881
CAS:ZM323881 is a potent and selective inhibitor of VEGFR2 with an IC 50 of less than 2 nM.Formula:C22H18FN3O2Colore e forma:SolidPeso molecolare:375.4SSR128129E
CAS:SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.Formula:C18H15N2O4·NaPurezza:98.79% - ≥95%Colore e forma:SolidPeso molecolare:346.31AMG 925
CAS:AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.Formula:C26H29N7O2Purezza:99.75%Colore e forma:SolidPeso molecolare:471.55PF-06651600 malonate
CAS:PF-06651600 is a potent and selective JAK3 inhibitor.Formula:C18H23N5O5Colore e forma:SolidPeso molecolare:389.41SU 4313
CAS:SU 4313 is a bioactive chemical.Formula:C18H17NOPurezza:99.51% - 99.89%Colore e forma:SolidPeso molecolare:263.33BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purezza:97.71% - 99.89%Colore e forma:SolidPeso molecolare:439.39ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurezza:98.05%Colore e forma:SolidPeso molecolare:367.91EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Formula:C17H16BrN3O2Purezza:99.087% - 99.88%Colore e forma:SolidPeso molecolare:374.23BAY 61-3606 HCl
CAS:BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formula:C20H19ClN6O3Colore e forma:SolidPeso molecolare:426.86SB1317 hydrochloride (1204918-72-8(free base))
SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).Formula:C23H25ClN4OPurezza:99.84%Colore e forma:SolidPeso molecolare:408.92TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurezza:99.28% - 99.82%Colore e forma:SolidPeso molecolare:380.85MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurezza:98.53%Colore e forma:SolidPeso molecolare:314.38AMG 925 HCl
CAS:AMG 925 HCl is a selective and potent dual inhibitor of FLT3 (IC50: 2±1 nM) and CDK4 (IC50: 3±1 nM).Formula:C26H30ClN7O2Colore e forma:SolidPeso molecolare:508.02G-749
CAS:G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.Formula:C25H25BrN6O2Purezza:98.32% - 99.60%Colore e forma:SolidPeso molecolare:521.41Seralutinib
CAS:<p>Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.</p>Formula:C27H27N5O3Purezza:99.09%Colore e forma:SolidPeso molecolare:469.54Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purezza:95.37% - 99.82%Colore e forma:Dark Green To Black SolidPeso molecolare:718.79CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurezza:97.36% - 97.59%Colore e forma:SolidPeso molecolare:368.46Vactosertib Hydrochloride
CAS:Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an ALK5 inhibitor, a TGF-β receptor I inhibitor with antimetastatic and anticancer effects.Formula:C22H19ClFN7Purezza:98.03%Colore e forma:SolidPeso molecolare:435.89Endoxifen (Z-isomer)
CAS:Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.Formula:C25H27NO2Purezza:99.19% - 99.81%Colore e forma:SolidPeso molecolare:373.49VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formula:C24H20Cl2FN5O2Purezza:98.92% - ≥98%Colore e forma:SolidPeso molecolare:500.35VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formula:C19H24N8Purezza:99.92%Colore e forma:SolidPeso molecolare:364.45ASP5878
CAS:ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.Formula:C18H19F2N5O4Purezza:99.8% - 99.89%Colore e forma:SolidPeso molecolare:407.37CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formula:C26H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:428.53Poziotinib
CAS:Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formula:C23H21Cl2FN4O3Purezza:98.69% - 99.78%Colore e forma:SolidPeso molecolare:491.34WS3
CAS:WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Formula:C28H30F3N7O3Purezza:97.93% - 99.94%Colore e forma:SolidPeso molecolare:569.58Alectinib
CAS:Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formula:C30H34N4O2Purezza:98% - 99.38%Colore e forma:SolidPeso molecolare:482.62Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurezza:98% - 99.91%Colore e forma:Physical Description White Powder (Ntp 1992)Peso molecolare:301.32CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purezza:99.68%Colore e forma:White To Off-White SolidPeso molecolare:294.3Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurezza:99.03% - 99.79%Colore e forma:SolidPeso molecolare:522.96(E)-AG 99
CAS:(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).Formula:C10H8N2O3Purezza:99.23%Colore e forma:SolidPeso molecolare:204.18AG-1557 hydrochloride (189290-58-2(free base))
AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).Formula:C16H15ClIN3O2Purezza:98.64%Colore e forma:SolidPeso molecolare:443.66URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purezza:99.32% - 99.98%Colore e forma:SolidPeso molecolare:421.54Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Formula:C28H33N7O2Purezza:99.32% - >99.99%Colore e forma:SolidPeso molecolare:499.61(Z)-Semaxinib
CAS:(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition forFormula:C15H14N2OPurezza:98.82% - ≥95%Colore e forma:SolidPeso molecolare:238.28Avitinib maleate
CAS:Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.Formula:C30H30FN7O6Purezza:98% - 99.74%Colore e forma:SolidPeso molecolare:603.61CEP-37440
CAS:CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).Formula:C30H38ClN7O3Purezza:98.86% - 99.98%Colore e forma:SolidPeso molecolare:580.12R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Formula:C22H23FN6O5Purezza:97.64% - 99.11%Colore e forma:SolidPeso molecolare:470.45Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purezza:99.52%Colore e forma:SolidPeso molecolare:346.81Tyrphostin B44, (+) enantiomer
CAS:Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Formula:C18H16N2O3Purezza:97.18%Colore e forma:SolidPeso molecolare:308.33Tyrphostin A1
CAS:Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formula:C11H8N2OPurezza:98.32%Colore e forma:SolidPeso molecolare:184.19Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurezza:99.93%Colore e forma:SolidPeso molecolare:728.79ASP3026
CAS:ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.Formula:C29H40N8O3SPurezza:98.78% - 99.81%Colore e forma:SolidPeso molecolare:580.74Bafetinib
CAS:<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Formula:C30H31F3N8OPurezza:94.16% - 99.68%Colore e forma:SolidPeso molecolare:576.62SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purezza:99.46%Colore e forma:SolidPeso molecolare:265.31PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formula:C19H23N9O·HClPurezza:97.7% - 99.81%Colore e forma:SolidPeso molecolare:429.91AG 1406
CAS:<p>AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.</p>Formula:C16H18N2OPurezza:98.12%Colore e forma:SolidPeso molecolare:254.33Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:468.47PF-431396
CAS:PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).Formula:C22H21F3N6O3SPurezza:98.83% - 99.82%Colore e forma:SolidPeso molecolare:506.5Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Naluzotan
CAS:Naluzotan（PRX 00023） is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+Formula:C23H38N4O3SPurezza:>99.99%Colore e forma:SolidPeso molecolare:450.64Filgotinib maleate
CAS:<p>Filgotinib maleate, a selective oral JAK1 inhibitor, treats RA and Crohn's. IC50s: JAK1-10nM, JAK2-28nM, JAK3-810nM, TYK2-116nM.</p>Formula:C25H27N5O7SColore e forma:SolidPeso molecolare:541.58
![5-phenylthieno[2,3-d]pyrimidin-4-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT50042.webp&w=3840&q=75)
