Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(166 prodotti)
- Bcr-Abl(117 prodotti)
- EGFR(551 prodotti)
- FAK(72 prodotti)
- FLT(88 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(176 prodotti)
- JAK(243 prodotti)
- PDGFR(127 prodotti)
- RAAS(86 prodotti)
- Src(82 prodotti)
- Syk(37 prodotti)
- Trombina(51 prodotti)
- VDA(2 prodotti)
- VEGFR(236 prodotti)
Mostrare 6 più sottocategorie
Trovati 2269 prodotti di "Angiogenesi"
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Ceritinib dihydrochloride
CAS:Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase with antitumour effect.Formula:C28H38Cl3N5O3SPurezza:99.85% - 99.99%Colore e forma:SolidPeso molecolare:631.06CH5424802 analog
CAS:CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.Formula:C28H30N4O2Purezza:98.96%Colore e forma:SolidPeso molecolare:454.56Ref: TM-T9224
1mg124,00€5mg271,00€10mg408,00€25mg672,00€50mg945,00€100mg1.279,00€1mL*10mM (DMSO)324,00€RO495
CAS:RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assaysFormula:C17H14Cl2N6OPurezza:97.94%Colore e forma:SolidPeso molecolare:389.24Ref: TM-T22416
1mg46,00€5mg86,00€10mg126,00€25mg235,00€50mg344,00€100mg465,00€200mg625,00€1mL*10mM (DMSO)94,00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purezza:98.92% - 99.52%Colore e forma:SolidPeso molecolare:310.35AZD-1480
CAS:AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.Formula:C14H14ClFN8Purezza:98.25% - 99.47%Colore e forma:SolidPeso molecolare:348.77GNF-5
CAS:GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.Formula:C20H17F3N4O3Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:418.37CEP-28122
CAS:CEP-28122 is a highly potent and selective orally active ALK inhibitor.Formula:C28H35ClN6O3Purezza:99.87% - >99.99%Colore e forma:SolidPeso molecolare:539.07Baricitinib phosphate
CAS:Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.Formula:C16H20N7O6PSPurezza:99.4% - 99.91%Colore e forma:SolidPeso molecolare:469.41Ref: TM-T2360
5mg40,00€10mg52,00€25mg73,00€50mg93,00€100mg105,00€200mg157,00€500mg260,00€1mL*10mM (DMSO)46,00€SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurezza:99.56%Colore e forma:SolidPeso molecolare:336.15Ref: TM-T8719
1mg43,00€5mg87,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€1mL*10mM (DMSO)94,00€S49076 HCl
CAS:S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3.Formula:C22H18ClN3O5Purezza:98%Colore e forma:SolidPeso molecolare:439.85Remibrutinib
CAS:Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.Formula:C27H27F2N5O3Purezza:99.5% - 99.81%Colore e forma:SolidPeso molecolare:507.53Ref: TM-T16730
1mg92,00€5mg210,00€10mg340,00€25mg572,00€50mg713,00€100mg1.099,00€200mg1.485,00€1mL*10mM (DMSO)235,00€Itacitinib
CAS:Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.Formula:C26H23F4N9OPurezza:96.4% - 99.5%Colore e forma:SolidPeso molecolare:553.51Oclacitinib maleate
CAS:Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formula:C15H23N5O2S·C4H4O4Purezza:99.17% - 99.92%Colore e forma:SolidPeso molecolare:453.51Ref: TM-T6914
1mg37,00€2mg52,00€5mg74,00€10mg94,00€25mg166,00€50mg258,00€100mg432,00€1mL*10mM (DMSO)81,00€Ruxolitinib
CAS:Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formula:C17H18N6Purezza:99.4% - >99.99%Colore e forma:SolidPeso molecolare:306.36Ref: TM-T1829
5mg55,00€10mg71,00€25mg96,00€50mg110,00€100mg146,00€200mg231,00€500mg393,00€1mL*10mM (DMSO)62,00€JAK-IN-5 hydrochloride
CAS:JAK-IN-5 hydrochloride is a JAK inhibitor [1].Formula:C27H32ClFN6OColore e forma:SolidPeso molecolare:511.03Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purezza:99.19% - 99.75%Colore e forma:SolidPeso molecolare:504.49LDN193189
CAS:LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.Formula:C25H22N6Purezza:98% - 99.86%Colore e forma:SolidPeso molecolare:406.48Vodobatinib
CAS:Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.Formula:C27H20ClN3O2Purezza:99.06% - 99.55%Colore e forma:SolidPeso molecolare:453.92Ref: TM-T8882
1mg34,00€5mg74,00€10mg110,00€25mg200,00€50mg323,00€100mg500,00€500mg1.209,00€1mL*10mM (DMSO)82,00€Upadacitinib
CAS:Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.Formula:C17H19F3N6OPurezza:98.96% - 99.94%Colore e forma:SolidPeso molecolare:380.37Ref: TM-T7503
2mg55,00€5mg89,00€10mg116,00€25mg198,00€50mg276,00€100mg389,00€200mg595,00€1mL*10mM (DMSO)44,00€Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormula:C28H22F3N7O·HCl·H2OPurezza:99.93%Colore e forma:SolidPeso molecolare:583.99
