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Angiogenesi

Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

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Trovati 2092 prodotti di "Angiogenesi"

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  • MET kinase-IN-3
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    MET kinase-IN-3

    CAS:
    MET kinase-IN-3 is a potent, orally active MET inhibitor (IC50: 9.8 nM) that exhibits good broad-spectrum anti-proliferative effects on cancer cells.
    Formula:C25H16ClF2N5O2
    Colore e forma:Solid
    Peso molecolare:491.88

    Ref: TM-T63309

  • KB SRC 4
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    KB SRC 4

    CAS:
    KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4
    Formula:C32H23ClN8
    Purezza:98.83% - 99.34%
    Colore e forma:Solid
    Peso molecolare:555.03

    Ref: TM-T11745

  • PF-06459988
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    PF-06459988

    CAS:
    PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.
    Formula:C19H22ClN7O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:431.88

    Ref: TM-T16492

  • HDAC-IN-50
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    HDAC-IN-50

    CAS:
    HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.
    Formula:C31H41N7O4
    Colore e forma:Solid
    Peso molecolare:575.7

    Ref: TM-T73179

  • BGB-102
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    BGB-102

    CAS:
    <p>BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3.</p>
    Formula:C22H25BrN4O2
    Purezza:99.02%
    Colore e forma:Solid
    Peso molecolare:457.36

    Ref: TM-T10531

  • EVT801
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    EVT801

    CAS:
    EVT801 is a highly selective and low-toxic VEGFR-3 inhibitor that inhibits VEGF-C-induced tumor lymphoid and angiogenesis and reduces CCL4, CCL5 and MDSC.
    Formula:C19H21N5O3
    Purezza:97.4%
    Colore e forma:Solid
    Peso molecolare:367.4

    Ref: TM-T73516

  • Pirtobrutinib
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    Pirtobrutinib

    CAS:
    Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.
    Formula:C22H21F4N5O3
    Purezza:99.76% - 99.94%
    Colore e forma:Solid
    Peso molecolare:479.43

    Ref: TM-T36287

  • (Rac)-PF-06250112
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    (Rac)-PF-06250112

    CAS:
    (Rac)-PF-0625011 is a racemic mix, orally active, selective BTK inhibitor, also targeting BMX and TEC kinases.
    Formula:C22H20F2N6O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:438.43

    Ref: TM-T12673

  • Henatinib
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    Henatinib

    CAS:
    Henatinib: orally active multi-kinase inhibitor targeting VEGFR-2, c-kit, PDGFR with antitumor effects.
    Formula:C25H29FN4O4
    Colore e forma:Solid
    Peso molecolare:468.52

    Ref: TM-T63011

  • Sulfatinib
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    Sulfatinib

    CAS:
    <p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>
    Formula:C24H28N6O3S
    Purezza:99.21% - >99.99%
    Colore e forma:Solid
    Peso molecolare:480.58

    Ref: TM-T4075

  • EGFR-IN-29
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    EGFR-IN-29

    CAS:
    EGFR-IN-29 is a potent EGFR inhibitor.
    Formula:C36H46BrN8O2P
    Colore e forma:Solid
    Peso molecolare:733.68

    Ref: TM-T73106

  • VEGFR-2-IN-37
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    VEGFR-2-IN-37

    CAS:
    VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.
    Formula:C18H16N2O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:324.4

    Ref: TM-T80872

  • BTK-IN-18
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    BTK-IN-18

    CAS:
    BTK-IN-18 is a potent, reversible inhibitor of Bruton's tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 µM.
    Formula:C20H22Cl2N6O
    Colore e forma:Solid
    Peso molecolare:433.33

    Ref: TM-T73318

  • ALK/EGFR-IN-1
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    ALK/EGFR-IN-1

    CAS:
    ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their phosphorylation.
    Formula:C27H34ClN7O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:572.12

    Ref: TM-T79392

  • NMS-P953
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    NMS-P953

    CAS:
    NMS-P953: JAK2 inhibitor, reduces tumor growth in SET-2 model, confirmed in vivo action, good pharmacokinetics and safety.
    Formula:C16H11ClF3N5O
    Colore e forma:Solid
    Peso molecolare:381.74

    Ref: TM-T70754

  • TG 100572 Hydrochloride
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    TG 100572 Hydrochloride

    CAS:
    <p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>
    Formula:C26H27Cl2N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:512.43

    Ref: TM-T13156L

  • Famitinib malate
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    Famitinib malate

    CAS:
    Famitinib malate (SHR1020) is a potent oral kinase inhibitor targeting c-kit, VEGFR-2, and PDGFRβ, with IC50s 2.3, 4.7, 6.6 nM, useful for cancer research.
    Formula:C27H33FN4O7
    Colore e forma:Solid
    Peso molecolare:544.57

    Ref: TM-T71111

  • 2′-Thioadenosine
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    2′-Thioadenosine

    CAS:
    2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against
    Formula:C10H13N5O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:283.31

    Ref: TM-T78634

  • FLT3-IN-14
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    FLT3-IN-14

    CAS:
    FLT3-IN-14: FLT3 inhibitor; FLT3-WT IC50=5.6nM, FLT3-ITD IC50=1.4nM; blocks Y591 phosphorylation; G1 arrest; pro-apoptotic.
    Formula:C25H24N6O2S
    Colore e forma:Solid
    Peso molecolare:472.56

    Ref: TM-T63058

  • 10Z-Hymenialdisine
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    10Z-Hymenialdisine

    CAS:
    Pan kinase inhibitor
    Formula:C11H10BrN5O2
    Purezza:98%
    Colore e forma:Light Yellow Solid
    Peso molecolare:324.13

    Ref: TM-T22470