Ferroptosi
La ferroptosi è una forma di morte cellulare regolata caratterizzata dall'accumulo di perossidi lipidici e dallo stress ossidativo dipendente dal ferro. A differenza dell'apoptosi, la ferroptosi non è guidata dalle caspasi, ma piuttosto dal fallimento delle difese antiossidanti cellulari, che porta alla morte cellulare. Gli inibitori e gli induttori della ferroptosi sono fondamentali per studiare questa particolare via di morte cellulare, implicata in varie malattie, tra cui il cancro, la neurodegenerazione e il danno da ischemia-riperfusione. Presso CymitQuimica, offriamo una vasta gamma di modulatori della ferroptosi di alta qualità per supportare la tua ricerca sui meccanismi di morte cellulare, stress ossidativo e patologia delle malattie.
Trovati 227 prodotti di "Ferroptosi"
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ZX703
ZX703 is a protein hydrolysis-targeting chimera (PROTAC) that mediates the degradation of GPX4 through the ubiquitin-proteasome and autophagy-lysosome pathways, with a DC50 of 0.315 µM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby promoting ferroptosis in cancer cells.Formula:C54H67ClN8O9SPeso molecolare:1039.69Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:Iron(III) compound induces ferroptosis in NB1 cells at 3μM, not apoptosis/necroptosis; inhibits various cancers, effective against drug-resistant NALM-6.Formula:C20H14ClFeN2O2Colore e forma:SolidPeso molecolare:405.64CQ-ER
CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).Formula:C33H33N7O6SColore e forma:SolidPeso molecolare:655.72W1131 TFA
W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.Formula:C25H20F3N5O6Purezza:98.1%Colore e forma:SolidPeso molecolare:543.45Ref: TM-T80847
1mL*10mM (DMSO)Prezzo su richiesta1mg92,00€5mg188,00€10mg311,00€25mg628,00€50mg1.008,00€100mg1.596,00€84-B10
CAS:84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.Formula:C25H22F3NO5Purezza:99.76%Colore e forma:SolidPeso molecolare:473.44Ref: TM-T75268
1mg47,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg152,00€25mg289,00€50mg447,00€100mg670,00€200mg888,00€Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Purezza:98%Colore e forma:Odour SolidGPX4-IN-7
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.Formula:C25H23ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:478.93Ferroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A.Formula:C22H34O5Purezza:98%Colore e forma:SolidPeso molecolare:378.5Idebenone
CAS:Formula:C19H30O5Purezza:>98.0%(T)(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:338.44Cerivastatin sodium
CAS:Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.Formula:C26H33FNNaO5Purezza:98.50% - 99.67%Colore e forma:SolidPeso molecolare:481.53CuATSP
CAS:CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.Formula:C18H18CuN6S2Purezza:97.09%Colore e forma:SolidPeso molecolare:446.05CuATSM
CAS:Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.Formula:C8H14CuN6S2Colore e forma:SolidPeso molecolare:321.92CCW16
CAS:CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.Formula:C22H20ClNO3Purezza:97%Colore e forma:SolidPeso molecolare:381.85BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:525.53Ref: TM-T2488
1mg34,00€2mg40,00€5mg59,00€1mL*10mM (DMSO)70,00€10mg96,00€25mg200,00€50mg334,00€100mg557,00€UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurezza:99.62%Colore e forma:SolidPeso molecolare:508.12Ref: TM-T8662
1mgPrezzo su richiesta2mg49,00€5mg80,00€1mL*10mM (DMSO)89,00€10mg111,00€25mg160,00€50mg202,00€100mg283,00€200mg419,00€Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Formula:C15H12O6Colore e forma:SolidPeso molecolare:288.25TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purezza:99.17% - 99.53%Colore e forma:White Solid PowderPeso molecolare:166.22Ferrostatin-1
CAS:Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!Formula:C15H22N2O2Purezza:96.1% - 99.68%Colore e forma:SolidPeso molecolare:262.35Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormula:C21H26N7Na4O17P3Purezza:97.15% - >99.99%Colore e forma:SolidPeso molecolare:833.35L-Glutamic acid monosodium salt
CAS:L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Formula:C5H8NO4·NaPurezza:99.93%Colore e forma:White Solid CrystallinePeso molecolare:169.11Coenzyme Q10
CAS:Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.Formula:C59H90O4Purezza:99.14% - 99.88%Colore e forma:DrypowderPeso molecolare:863.34SP-420
CAS:SP-420 is a novel orally active iron chelator.Formula:C16H21NO6SPurezza:99.39%Colore e forma:SolidPeso molecolare:355.41ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formula:C22H20Cl2N4O4Purezza:97% - 99.03%Colore e forma:SolidPeso molecolare:475.32Ref: TM-T8375
1mg34,00€2mg49,00€5mg82,00€1mL*10mM (DMSO)86,00€10mg133,00€25mg234,00€50mg393,00€100mg528,00€Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurezza:98% - 99.8%Colore e forma:Yellow SolidPeso molecolare:441.54Ref: TM-T3170
2mg42,00€5mg62,00€1mL*10mM (DMSO)85,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formula:C8H18N2O3SPurezza:97.07% - ≥98%Colore e forma:White Fine PowderPeso molecolare:222.31DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurezza:98% - 99.64%Colore e forma:White Fine PowderPeso molecolare:222.31SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Formula:C26H32N4O2Purezza:97.73%Colore e forma:SolidPeso molecolare:432.56Ref: TM-T9073
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)89,00€10mg108,00€25mg203,00€50mg306,00€100mg459,00€Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:432.46Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurezza:99.76% - 99.94%Colore e forma:White SolidPeso molecolare:249.33Ref: TM-T1934
2mg34,00€5mg48,00€1mL*10mM (DMSO)58,00€10mg63,00€25mg80,00€50mg117,00€100mg187,00€200mg243,00€Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Formula:C18H28N2OPurezza:99.72%Colore e forma:SolidPeso molecolare:288.43Ref: TM-T1787
5mg46,00€1mL*10mM (DMSO)47,00€10mg59,00€25mg87,00€50mg129,00€100mg178,00€200mg268,00€500mg460,00€Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formula:C19H21ClN4Purezza:97.11% - 99.44%Colore e forma:SolidPeso molecolare:340.85Ref: TM-T2376
1mg39,00€5mg85,00€1mL*10mM (DMSO)85,00€10mg130,00€25mg244,00€50mg390,00€100mg495,00€200mg712,00€Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurezza:99.63% - 99.79%Colore e forma:SolidPeso molecolare:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurezza:97.63% - 99.82%Colore e forma:SolidPeso molecolare:220.23NADPH tetracyclohexanamine
CAS:NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.
Formula:C45H82N11O17P3Purezza:98.73% - 99.05%Colore e forma:SolidPeso molecolare:1142.12L-Cystine
CAS:L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation ofFormula:C6H12N2O4S2Purezza:99.59% - 99.85%Colore e forma:White Solid PowderPeso molecolare:240.3Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurezza:98.61% - 99.87%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:357.43JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purezza:98.02% - 98.4%Colore e forma:SolidPeso molecolare:451.3Ref: TM-T37314
1mg49,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg170,00€25mg281,00€50mg439,00€100mg708,00€200mg964,00€L-Glutamic acid
CAS:L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!Formula:C5H9NO4Purezza:99.14% - 99.55%Colore e forma:White Solid CrystallinePeso molecolare:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Formula:C29H25N3O4SPurezza:98.08% - >99.99%Colore e forma:SolidPeso molecolare:511.59Ref: TM-T4360
5mg49,00€1mL*10mM (DMSO)56,00€10mg74,00€25mg144,00€50mg230,00€100mg356,00€200mg532,00€500mg852,00€Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurezza:99.25% - >99.99%Colore e forma:SolidPeso molecolare:259.33Ref: TM-T1847
5mg34,00€10mg50,00€1mL*10mM (DMSO)50,00€25mg78,00€50mg107,00€100mg166,00€200mg236,00€500mg398,00€Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFormula:C30H32ClFN2OPurezza:99.72% - >99.99%Colore e forma:SolidPeso molecolare:491.04Ref: TM-T1885
1mg57,00€2mg84,00€5mg105,00€1mL*10mM (DMSO)114,00€10mg170,00€25mg334,00€50mg500,00€100mg705,00€Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purezza:97.81% - 99.09%Colore e forma:SolidPeso molecolare:505.69Trigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Formula:C7H7NO2Purezza:97.585% - 99.49%Colore e forma:Prisms Aqueous From Alcohol + Water SolidPeso molecolare:137.14WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purezza:97.41% - 99.99%Colore e forma:SolidPeso molecolare:470.60Ref: TM-T5687
1mg80,00€5mg251,00€1mL*10mM (DMSO)288,00€10mg371,00€25mg620,00€50mg880,00€100mg1.189,00€500mg2.385,00€PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purezza:99.22%Colore e forma:SolidPeso molecolare:185.22Ref: TM-T6954
5mg49,00€1mL*10mM (DMSO)54,00€10mg70,00€25mg133,00€50mg195,00€100mg349,00€200mg518,00€500mg830,00€Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purezza:99.94% - >99.99%Colore e forma:White PowderPeso molecolare:461.51Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formula:C18H21N5O2Purezza:99.63%Colore e forma:SolidPeso molecolare:339.39Ref: TM-T6192
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg60,00€25mg81,00€50mg92,00€100mg129,00€200mg178,00€Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formula:C33H34FN2O5CaPurezza:99.27% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:577.67Erastin
CAS:Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Formula:C30H31ClN4O4Purezza:98% - 99.82%Colore e forma:SolidPeso molecolare:547.04Ref: TM-T1765
1mg46,00€2x1mg59,00€5x1mg93,00€10x1mg120,00€25x1mg192,00€50x1mg284,00€100x1mg421,00€200x1mg618,00€Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purezza:98.90% - 99.90%Colore e forma:White To Fainly Beige Crystalline PowderPeso molecolare:250.29FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purezza:99.72% - 99.78%Colore e forma:SolidPeso molecolare:517.66Ref: TM-T4066
2mg42,00€5mg63,00€1mL*10mM (DMSO)72,00€10mg89,00€25mg192,00€50mg341,00€100mg535,00€200mg748,00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purezza:97.43% - 98.4%Colore e forma:SolidPeso molecolare:374.34Ref: TM-TJS1159
1mg57,00€5mg120,00€10mg178,00€1mL*10mM (DMSO)215,00€25mg329,00€50mg485,00€100mg692,00€500mg1.404,00€Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurezza:97.71% - >99.99%Colore e forma:SolidPeso molecolare:367.3Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Formula:C16H17BrN2SPurezza:99.24% - 99.74%Colore e forma:SolidPeso molecolare:349.29Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Colore e forma:SolidPeso molecolare:377.31L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Formula:C8H19ClN2O3SColore e forma:SolidPeso molecolare:258.77Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formula:C18H28N2O·HClPurezza:99.74%Colore e forma:White Crystalline PowderPeso molecolare:324.89Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Formula:C12H22FeN3O14Purezza:98%Colore e forma:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaPeso molecolare:488.16Pioglitazone potassium
CAS:Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.Formula:C19H19KN2O3SColore e forma:SolidPeso molecolare:394.53CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purezza:98.3% - 99.61%Colore e forma:SolidPeso molecolare:541.72Ref: TM-TQ0120
1mg34,00€5mg74,00€1mL*10mM (DMSO)89,00€10mg105,00€25mg200,00€50mg319,00€100mg485,00€500mg1.035,00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purezza:97.50%Colore e forma:Solid Off-WhitePeso molecolare:464.64(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFormula:C15H14O6Purezza:98.55% - 98.80%Colore e forma:SolidPeso molecolare:290.27CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Formula:C23H27N3O5S2Purezza:99.46% - 99.91%Colore e forma:SolidPeso molecolare:489.61Ref: TM-T4309
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)81,00€10mg109,00€25mg178,00€50mg284,00€100mg434,00€Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purezza:97.169% - 99.59%Colore e forma:Dark Purple Crystalline PowderPeso molecolare:651.94DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFormula:C15H24O2Purezza:99.06% - 99.17%Colore e forma:SolidPeso molecolare:236.35Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Formula:C15H20O3Purezza:98% - 99.8%Colore e forma:SolidPeso molecolare:248.32UAMC-3203
CAS:UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).Formula:C25H37N5O2SPurezza:97.052% - 99.72%Colore e forma:SolidPeso molecolare:471.66Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purezza:98.75% - 99.57%Colore e forma:SolidPeso molecolare:199.25Ref: TM-T4414
5mg70,00€1mL*10mM (DMSO)77,00€10mg100,00€25mg195,00€50mg349,00€100mg618,00€500mg1.251,00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purezza:99.99%Colore e forma:White Or Off-White PowderPeso molecolare:146.14RSL3
CAS:View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.Formula:C23H21ClN2O5Purezza:98% - 99.96%Colore e forma:SolidPeso molecolare:440.88Ref: TM-T3646
1mg37,00€2mg49,00€1mL*10mM (DMSO)71,00€5mg74,00€10mg119,00€25mg244,00€50mg331,00€100mg434,00€500mg973,00€1g1.288,00€Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purezza:97.03% - 99.90%Colore e forma:SolidPeso molecolare:317.34DL-α-Tocopherol
CAS:DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.Formula:C29H50O2Purezza:99.61% - 99.90%Colore e forma:Light Yellow Liquid ViscousPeso molecolare:430.71(E)-Ferulic acid
CAS:(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression ofFormula:C10H10O4Purezza:99.63%Colore e forma:SolidPeso molecolare:194.18SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purezza:98.58%Colore e forma:SolidPeso molecolare:352.47Ref: TM-T8922
1mg46,00€5mg80,00€1mL*10mM (DMSO)105,00€10mg116,00€25mg227,00€50mg359,00€100mg550,00€500mg1.159,00€Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formula:C11H11NO4SPurezza:98.71%Colore e forma:SolidPeso molecolare:253.27Ref: TM-T19692
1mg99,00€1mL*10mM (DMSO)205,00€5mg222,00€10mg344,00€25mg550,00€50mg773,00€100mg1.063,00€ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurezza:98.42% - 99.55%Colore e forma:SolidPeso molecolare:477.4Ref: TM-T8970
1mg43,00€5mg85,00€1mL*10mM (DMSO)92,00€10mg110,00€25mg215,00€50mg334,00€100mg467,00€200mg672,00€1R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Formula:C23H21ClN2O5Purezza:99.51%Colore e forma:SolidPeso molecolare:440.88Ref: TM-T9561
1mg86,00€5mg177,00€1mL*10mM (DMSO)207,00€10mg265,00€25mg427,00€50mg605,00€100mg800,00€200mg1.071,00€Piperazine Erastin
CAS:Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.Formula:C35H41ClN6O4Purezza:99.52%Colore e forma:SolidPeso molecolare:645.19Ref: TM-T16540
1mg92,00€5mg165,00€1mL*10mM (DMSO)227,00€10mg268,00€25mg537,00€50mg879,00€100mg1.161,00€200mg1.594,00€500mg2.367,00€PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formula:C15H11NSPurezza:98.00%Colore e forma:SolidPeso molecolare:237.32Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Formula:C21H19ClN4O2Purezza:93.468% - 99.31%Colore e forma:SolidPeso molecolare:394.85Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Formula:C14H15N5SPurezza:99% - 99.02%Colore e forma:SolidPeso molecolare:285.37FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formula:C15H28O3Purezza:97.27%Colore e forma:SoildPeso molecolare:256.38Anti-Mouse IL-1b Antibody (B122)
Anti-Mouse IL-1b Antibody (B122) is a mab inhibitor, blocks IL-1β signaling, reducing monocyte infiltration and alleviating T cell exhaustion.Colore e forma:Odour LiquidMicrotubule inhibitor 8
CAS:Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].Formula:C21H15N3O2SColore e forma:SolidPeso molecolare:373.43Frataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Formula:C20H23NO6Purezza:99.34%Colore e forma:SolidPeso molecolare:373.4Pioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Formula:C19H20N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:360.46IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Colore e forma:SolidPeso molecolare:368.47Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purezza:98%Colore e forma:SolidPeso molecolare:578.58Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Formula:C17H24ClN3O2Peso molecolare:337.84W1131
CAS:W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Formula:C23H19N5O4Colore e forma:SolidPeso molecolare:429.43Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formula:C22H19N3O5Colore e forma:SolidPeso molecolare:405.4CGP 65015
CAS:CGP 65015 is an oral iron chelator and can mobilize iron deposits.Formula:C14H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:261.27Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Colore e forma:SolidPeso molecolare:464.9NPD4928
CAS:NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formula:C29H32N2O6Colore e forma:SolidPeso molecolare:504.57CN128 hydrochloride
CAS:CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.
Formula:C15H18ClNO3Colore e forma:SolidPeso molecolare:295.76YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.Formula:C25H26N6OColore e forma:SolidPeso molecolare:426.51FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurezza:99.44%Colore e forma:SolidPeso molecolare:468.54HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Formula:C20H24N2O6Purezza:97.35% - 98.58%Colore e forma:SolidPeso molecolare:388.41BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Formula:C23H19Cl2N3OSPurezza:99.49%Colore e forma:SolidPeso molecolare:456.39
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