Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formula:C20H19ClFN5OSPurezza:99.09% - 99.79%Colore e forma:SolidPeso molecolare:431.91ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurezza:98.05%Colore e forma:SolidPeso molecolare:367.91Tazemetostat hydrobromide
CAS:Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).Formula:C34H45BrN4O4Purezza:99.8%Colore e forma:SolidPeso molecolare:653.65Ref: TM-T17002
2mg43,00€5mg60,00€10mg81,00€50mg96,00€100mg159,00€200mg230,00€500mg378,00€1mL*10mM (DMSO)84,00€SGC707
CAS:SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.Formula:C16H18N4O2Purezza:99.75% - 99.89%Colore e forma:SolidPeso molecolare:298.34BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purezza:98.58% - 99.64%Colore e forma:SolidPeso molecolare:490.64Ref: TM-T7697
1mg40,00€5mg85,00€10mg117,00€25mg207,00€50mg311,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)131,00€3-deazaneplanocin A HCl
CAS:3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.Formula:C12H15ClN4O3Purezza:93.24% - 98.9%Colore e forma:SolidPeso molecolare:298.73JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formula:C16H15N3O3Purezza:98% - 99.81%Colore e forma:SolidPeso molecolare:297.31Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Formula:C29H34FN3O5SPurezza:99.82%Colore e forma:SolidPeso molecolare:555.66SGC2085
CAS:SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formula:C19H24N2O2Purezza:99.61% - 99.71%Colore e forma:SolidPeso molecolare:312.41Ref: TM-T7089
1mg88,00€2mg119,00€5mg227,00€10mg341,00€25mg563,00€50mg820,00€100mg1.130,00€1mL*10mM (DMSO)160,00€Hinokitiol
CAS:Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.Formula:C10H12O2Purezza:99.49% - 99.98%Colore e forma:SolidPeso molecolare:164.2Peficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formula:C18H22N4O2Purezza:98.67% - 99.4%Colore e forma:SolidPeso molecolare:326.39Ref: TM-T6933
2mg40,00€5mg66,00€10mg104,00€25mg182,00€50mg283,00€100mg439,00€200mg645,00€1mL*10mM (DMSO)73,00€GSK-5959
CAS:GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formula:C22H26N4O3Purezza:98.35% - 98.65%Colore e forma:SolidPeso molecolare:394.47SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurezza:97.82%Colore e forma:SolidPeso molecolare:453.47Ref: TM-T8685
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€TP0463518
CAS:TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).Formula:C20H18ClN3O6Purezza:99.52%Colore e forma:SolidPeso molecolare:431.83Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purezza:99.79% - 99.82%Colore e forma:SolidPeso molecolare:298.34WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formula:C39H38F3N7O5Purezza:99.41%Colore e forma:SolidPeso molecolare:741.76Ref: TM-T9219
1mg40,00€2mg52,00€5mg88,00€10mg137,00€25mg264,00€50mg419,00€100mg617,00€1mL*10mM (DMSO)87,00€Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formula:C17H18N6Purezza:99.4% - >99.99%Colore e forma:SolidPeso molecolare:306.36Amodiaquine hydrochloride
CAS:Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.Formula:C20H24Cl3N3OColore e forma:SolidPeso molecolare:428.78Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurezza:98.24% - 99.80%Colore e forma:SolidPeso molecolare:323.36Ref: TM-T4463
2mg48,00€5mg73,00€10mg115,00€25mg173,00€50mg235,00€100mg364,00€200mg540,00€500mg869,00€1mL*10mM (DMSO)81,00€HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purezza:≥98%Colore e forma:SolidPeso molecolare:287.32Ref: TM-T50099
5mg39,00€10mg64,00€25mg117,00€50mg212,00€100mg316,00€200mg454,00€1mL*10mM (DMSO)47,00€KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurezza:98.43% - 99.69%Colore e forma:SolidPeso molecolare:332.4CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formula:C26H31BrN8OPurezza:98.51% - 99.89%Colore e forma:SolidPeso molecolare:551.48Ref: TM-T2611
1mg42,00€5mg79,00€10mg92,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)95,00€Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg96,00€5mg215,00€10mg369,00€25mg610,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)235,00€AZ9482
CAS:AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.Formula:C26H22N6O2Purezza:99.18% - 99.86%Colore e forma:SolidPeso molecolare:450.49Ref: TM-T22264
1mg57,00€5mg131,00€10mg205,00€25mg389,00€50mg565,00€100mg822,00€1mL*10mM (DMSO)140,00€BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurezza:97.69% - 99.98%Colore e forma:SolidPeso molecolare:432.52PARP1-IN-5 dihydrochloride
CAS:PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.Formula:C25H26Cl2N2O5SPurezza:98.01%Colore e forma:SolidPeso molecolare:537.46GSK121
CAS:<p>GSK121 is an inhibitor of selective PAD4.</p>Formula:C25H26F3N5O3Purezza:98.92%Colore e forma:SolidPeso molecolare:501.51PJ34
CAS:<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Formula:C17H17N3O2Purezza:95.05% - 99.85%Colore e forma:SolidPeso molecolare:295.34dBET1
CAS:dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formula:C38H37ClN8O7SPurezza:98.02% - 99.3%Colore e forma:SolidPeso molecolare:785.27Ref: TM-T4495
1mg52,00€5mg104,00€10mg170,00€25mg283,00€50mg452,00€100mg687,00€200mg938,00€1mL*10mM (DMSO)154,00€Ref: TM-T5S2358
1mg52,00€2mg72,00€5mg111,00€10mg144,00€25mg207,00€50mg311,00€100mg472,00€1mL*10mM (DMSO)123,00€Fedratinib hydrochloride hydrate
CAS:Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formula:C27H40Cl2N6O4SPurezza:98.96% - 99.87%Colore e forma:SolidPeso molecolare:615.61Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurezza:99.6%Colore e forma:SolidPeso molecolare:122.12MS049
CAS:MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formula:C15H24N2OPurezza:98.91%Colore e forma:SolidPeso molecolare:248.36Ref: TM-T4378
2mg35,00€5mg51,00€10mg85,00€25mg158,00€50mg235,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)55,00€PFI-3
CAS:PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.Formula:C19H19N3O2Purezza:99.58% - 99.94%Colore e forma:SolidPeso molecolare:321.37(S)-CPI203
CAS:CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurezza:99.01% - 99.92%Colore e forma:SolidPeso molecolare:399.9Ref: TM-T6026
2mg35,00€5mg58,00€10mg94,00€25mg178,00€50mg284,00€100mg449,00€200mg627,00€1mL*10mM (DMSO)62,00€Rucaparib tartrate
CAS:Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.Formula:C23H24FN3O7Colore e forma:SolidPeso molecolare:473.457GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formula:C25H23ClN2O3Purezza:98.34% - 99.85%Colore e forma:SolidPeso molecolare:434.91TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurezza:99.89%Colore e forma:SolidPeso molecolare:273.23CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurezza:97.36% - 97.59%Colore e forma:SolidPeso molecolare:368.46Windorphen
CAS:Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.Formula:C17H15ClO3Purezza:99.66%Colore e forma:SolidPeso molecolare:302.75ME0328
CAS:ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.Formula:C19H19N3O2Purezza:99.22%Colore e forma:SolidPeso molecolare:321.37ORY1001
CAS:<p>ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.</p>Formula:C15H22N2·2HClPurezza:99.85% - 99.96%Colore e forma:SolidPeso molecolare:303.27Ref: TM-T6922
1mg59,00€2mg84,00€5mg134,00€10mg234,00€25mg452,00€50mg660,00€100mg939,00€500mg1.882,00€UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formula:C29H44F2N6O2Purezza:98.75% - 99.5%Colore e forma:SolidPeso molecolare:546.7Ref: TM-T4166
1mg40,00€2mg52,00€5mg87,00€10mg131,00€25mg230,00€50mg378,00€100mg567,00€200mg825,00€1mL*10mM (DMSO)95,00€XL019
CAS:XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formula:C25H28N6O2Purezza:99.19%Colore e forma:SolidPeso molecolare:444.53Ref: TM-T3072
2mg46,00€5mg66,00€10mg97,00€25mg159,00€50mg226,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)82,00€DL-α-Hydroxyglutaric acid disodium salt
CAS:DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuranFormula:C5H6Na2O5Purezza:≥98%Colore e forma:SolidPeso molecolare:192.08AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purezza:98.6% - 99.85%Colore e forma:Yellow SolidPeso molecolare:294.3PIN1 inhibitor API-1
CAS:API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formula:C15H13F3N6O2Purezza:98.48%Colore e forma:SolidPeso molecolare:366.3Ref: TM-T16538
1mg60,00€5mg127,00€10mg235,00€25mg344,00€50mg512,00€100mg645,00€200mg898,00€500mg1.311,00€1mL*10mM (DMSO)140,00€UMB298
CAS:UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.Formula:C27H31ClN4O2Purezza:99.76%Colore e forma:SolidPeso molecolare:479.01Ref: TM-T9194
1mg48,00€5mg99,00€10mg158,00€25mg264,00€50mg370,00€100mg507,00€200mg657,00€1mL*10mM (DMSO)104,00€OG-L002
CAS:OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formula:C15H15NOPurezza:97.05% - 98.62%Colore e forma:SolidPeso molecolare:225.29Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purezza:97.88% - 98.79%Colore e forma:White PowderPeso molecolare:474.55UNC 669
CAS:UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formula:C15H20BrN3OPurezza:97.38%Colore e forma:SolidPeso molecolare:338.24RO8191
CAS:RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formula:C14H5F6N5OPurezza:98% - 98.85%Colore e forma:SolidPeso molecolare:373.21Ref: TM-T22142
1mg46,00€2mg58,00€5mg87,00€10mg144,00€25mg268,00€50mg401,00€100mg605,00€500mg1.254,00€MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFormula:C16H15ClFNPurezza:99.17%Colore e forma:SolidPeso molecolare:275.75Ref: TM-T9262
1mg40,00€5mg90,00€10mg131,00€25mg220,00€50mg314,00€100mg426,00€200mg575,00€1mL*10mM (DMSO)89,00€MM-102 TFA
CAS:MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.Formula:C37H50F5N7O6Purezza:99.4% - 99.78%Colore e forma:SolidPeso molecolare:783.83Ref: TM-T8768
1mg39,00€2mg51,00€5mg105,00€10mg168,00€25mg284,00€50mg420,00€100mg620,00€1mL*10mM (DMSO)149,00€G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formula:C25H16ClN7O3SPurezza:97.63% - 98.17%Colore e forma:SolidPeso molecolare:529.96MPT0G211 mesylate
CAS:MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formula:C18H19N3O5SColore e forma:SolidPeso molecolare:389.43Deoxyshikonin
CAS:<p>1.</p>Formula:C16H16O4Purezza:99.36% - ≥95%Colore e forma:SolidPeso molecolare:272.3Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurezza:98.03% - ≥95%Colore e forma:SolidPeso molecolare:425.5DR2313
CAS:DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formula:C8H10N2OSPurezza:98.65%Colore e forma:SolidPeso molecolare:182.24Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purezza:99.25% - 99.49%Colore e forma:SolidPeso molecolare:472.58CPI203
CAS:CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurezza:99.13% - 99.77%Colore e forma:SolidPeso molecolare:399.9ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purezza:99.11% - 99.59%Colore e forma:Pale Yellow SolidPeso molecolare:513.59JQKD82
CAS:JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formula:C27H40N4O5Purezza:100.00%Colore e forma:SolidPeso molecolare:500.63MS023
CAS:MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formula:C17H25N3OPurezza:98.31% - 99.87%Colore e forma:SolidPeso molecolare:287.4Ref: TM-T6900
1mg39,00€2mg51,00€5mg88,00€10mg119,00€25mg243,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)84,00€AZ6102
CAS:AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.Formula:C25H28N6OPurezza:97.98% - 99.91%Colore e forma:SolidPeso molecolare:428.53Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formula:C20H13N3O2Purezza:98.83%Colore e forma:Dark Red SolidPeso molecolare:327.34MK-3903
CAS:MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formula:C27H19ClN2O3Purezza:98.63% - 99.75%Colore e forma:SolidPeso molecolare:454.9Ref: TM-T5187
1mg35,00€5mg80,00€10mg120,00€25mg188,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)88,00€Ref: TM-T6S0071
2mg35,00€5mg52,00€10mg88,00€25mg160,00€50mg235,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)86,00€PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formula:C29H37ClN4O3Purezza:97.11% - 99.02%Colore e forma:SolidPeso molecolare:525.08OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurezza:99.49% - 99.65%Colore e forma:SolidPeso molecolare:237.26Ref: TM-T2040
1mg37,00€2mg49,00€5mg70,00€10mg97,00€25mg167,00€50mg316,00€100mg570,00€1mL*10mM (DMSO)70,00€I-BRD9
CAS:I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formula:C22H22F3N3O3S2Purezza:98.16% - 99.51%Colore e forma:SolidPeso molecolare:497.55Ref: TM-T6859
1mg40,00€2mg51,00€5mg74,00€10mg113,00€25mg215,00€50mg411,00€100mg610,00€1mL*10mM (DMSO)84,00€GSK 690 Hydrochloride
CAS:<p>GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.</p>Formula:C24H24ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:405.92C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Formula:C24H19N3O6Purezza:98% - 99.21%Colore e forma:SolidPeso molecolare:445.42Ref: TM-T2452
2mg48,00€5mg69,00€10mg97,00€25mg195,00€50mg380,00€100mg562,00€500mg1.206,00€1mL*10mM (DMSO)69,00€γ-Oryzanol
CAS:γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in theFormula:C40H58O4Purezza:mixture - mixtureColore e forma:White Or White Crystalline Powder OdourlessPeso molecolare:602.9Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurezza:96.17% - 97.49%Colore e forma:SolidPeso molecolare:488.54Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formula:C20H19D3N8O3Purezza:98.52% - >99.99%Colore e forma:SolidPeso molecolare:425.46Ref: TM-T14687
1mg59,00€5mg144,00€10mg261,00€25mg410,00€50mg607,00€100mg863,00€1mL*10mM (DMSO)158,00€NEO2734
CAS:NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).Formula:C22H24F3N3O3Purezza:98.72% - 98.8%Colore e forma:SolidPeso molecolare:435.44Ref: TM-T8658
1mg114,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€500mg2.822,00€1mL*10mM (DMSO)303,00€LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purezza:98.1% - 98.22%Colore e forma:SolidPeso molecolare:435.51Ref: TM-T3494
2mg47,00€5mg69,00€10mg89,00€25mg183,00€50mg298,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)69,00€SGI-1027
CAS:SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formula:C27H23N7OPurezza:99.45% - 99.78%Colore e forma:SolidPeso molecolare:461.52Ref: TM-T1904
5mg58,00€10mg94,00€25mg163,00€50mg296,00€100mg467,00€500mg1.035,00€1mL*10mM (DMSO)74,00€SGC-SMARCA-BRDVIII
CAS:SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,Formula:C19H25N5O3Purezza:99.54% - 99.92%Colore e forma:SolidPeso molecolare:371.43Ref: TM-T9568
1mg47,00€5mg70,00€10mg106,00€25mg235,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)57,00€Pim1/AKK1-IN-1
CAS:<p>Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.</p>Formula:C20H13N5OPurezza:97.03% - 98.69%Colore e forma:SolidPeso molecolare:339.35GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormula:C31H39N7O2Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:541.69Hispidulin
CAS:Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).Formula:C16H12O6Purezza:98.53% - 99.87%Colore e forma:SolidPeso molecolare:300.26Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formula:C30H52O3Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:460.73RK-287107
CAS:RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).Formula:C22H26F2N4O2Purezza:99.64%Colore e forma:SolidPeso molecolare:416.46Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formula:C19H36O5Purezza:99.85% - 99.94%Colore e forma:SolidPeso molecolare:344.49Ref: TM-T3625
2mg35,00€5mg52,00€10mg73,00€25mg125,00€50mg217,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)55,00€GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purezza:99.52% - >99.99%Colore e forma:SolidPeso molecolare:410.43Ref: TM-T3076
1mg40,00€2mg52,00€5mg88,00€10mg144,00€25mg264,00€50mg465,00€100mg658,00€500mg1.378,00€1mL*10mM (DMSO)87,00€EED226
CAS:EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formula:C17H15N5O3SPurezza:98.14% - 99.33%Colore e forma:SolidPeso molecolare:369.4Iniparib
CAS:Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).Formula:C7H5IN2O3Purezza:98.93%Colore e forma:SolidPeso molecolare:292.03Ref: TM-T6224
5mg50,00€10mg77,00€25mg126,00€50mg229,00€100mg359,00€200mg570,00€500mg912,00€1mL*10mM (DMSO)55,00€COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formula:C13H8Cl4N2OPurezza:98.96%Colore e forma:SolidPeso molecolare:350.03GSK620
CAS:<p>GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.</p>Formula:C18H19N3O3Purezza:99.42% - 99.88%Colore e forma:SolidPeso molecolare:325.36Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purezza:97.55% - 99.92%Colore e forma:SolidPeso molecolare:230.3MI-463
CAS:MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formula:C24H23F3N6SPurezza:99.18% - >99.99%Colore e forma:SolidPeso molecolare:484.54Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurezza:98.01%Colore e forma:SolidPeso molecolare:244.29MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purezza:98.07% - 98.26%Colore e forma:SolidPeso molecolare:476.86Ref: TM-T6315
1mg52,00€2mg71,00€5mg88,00€10mg127,00€25mg233,00€50mg376,00€100mg567,00€1mL*10mM (DMSO)93,00€dBET6
CAS:dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.Formula:C42H45ClN8O7SPurezza:97.57% - 99.12%Colore e forma:SolidPeso molecolare:841.37Ref: TM-T5130
1mg52,00€5mg97,00€10mg169,00€25mg306,00€50mg492,00€100mg712,00€200mg898,00€500mg1.311,00€1mL*10mM (DMSO)157,00€KC7F2
CAS:KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formula:C16H16Cl4N2O4S4Purezza:98% - 99.11%Colore e forma:SolidPeso molecolare:570.38Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurezza:99.65% - 99.79%Colore e forma:SolidPeso molecolare:404.44Ref: TM-T6255
1mg47,00€2mgPrezzo su richiesta5mg87,00€10mg140,00€25mg274,00€50mg439,00€100mg702,00€200mg938,00€1mL*10mM (DMSO)97,00€PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurezza:98.82%Colore e forma:SolidPeso molecolare:374.44Ref: TM-T8764
1mg113,00€2mg160,00€5mg230,00€10mg369,00€25mg615,00€50mg879,00€100mg1.198,00€500mg2.395,00€1mL*10mM (DMSO)240,00€MRTX-1719
CAS:<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Formula:C23H18ClFN6O2Purezza:98.27% - 99.18%Colore e forma:SolidPeso molecolare:464.88653-47 hydrochloride
CAS:653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).Formula:C20H20Cl2N2O3Purezza:99.14%Colore e forma:SolidPeso molecolare:407.29Ref: TM-T8890
1mg92,00€5mg187,00€10mg354,00€25mg597,00€50mg852,00€100mg1.159,00€500mg2.327,00€1mL*10mM (DMSO)215,00€AZ505
CAS:AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formula:C29H38Cl2N4O4Purezza:98.18%Colore e forma:SolidPeso molecolare:577.54Ref: TM-TQ0100
1mg64,00€5mg137,00€10mg188,00€25mg311,00€50mg487,00€100mg658,00€1mL*10mM (DMSO)168,00€Ruboxistaurin mesylate
CAS:Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.Formula:C29H32N4O6SPurezza:98%Colore e forma:SolidPeso molecolare:564.65AMI-1
CAS:<p>AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).</p>Formula:C21H14N2Na2O9S2Purezza:97.53% - 99.9%Colore e forma:DrypowderPeso molecolare:548.45WZ4003
CAS:WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formula:C25H29ClN6O3Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:496.99Ref: TM-T6291
5mg50,00€10mg77,00€25mg117,00€50mg170,00€100mg255,00€200mg378,00€500mg622,00€1mL*10mM (DMSO)52,00€MK-8617
CAS:<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Formula:C24H21N5O4Purezza:99.38% - >99.99%Colore e forma:SolidPeso molecolare:443.45NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formula:C27H34N4O5Purezza:99.59%Colore e forma:SolidPeso molecolare:494.58Ref: TM-T3261
1mg46,00€2mg57,00€5mg88,00€10mg129,00€25mg261,00€50mg444,00€100mg652,00€1mL*10mM (DMSO)87,00€5-Ph-IAA
CAS:<p>5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.</p>Formula:C16H13NO2Purezza:99.37% - 99.973%Colore e forma:SolidPeso molecolare:251.28UNC1999
CAS:UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).Formula:C33H43N7O2Purezza:99.19% - >99.99%Colore e forma:SolidPeso molecolare:569.74Ref: TM-T3057
1mg35,00€2mg48,00€5mg70,00€10mg97,00€25mg170,00€50mg274,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)89,00€GSK1379725A
CAS:<p>GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).</p>Formula:C23H23FN6O3Purezza:99.51%Colore e forma:SolidPeso molecolare:450.472,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Formula:C16H13Cl2N3O2Purezza:98.77%Colore e forma:SolidPeso molecolare:350.2MR837
CAS:MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formula:C16H14N2OSPurezza:99.77% - 99.85%Colore e forma:SolidPeso molecolare:282.36Ref: TM-T8879
2mg40,00€5mg58,00€10mg96,00€25mg145,00€50mg255,00€100mg375,00€200mg530,00€1mL*10mM (DMSO)70,00€RBN012759
CAS:RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.Formula:C19H23FN2O3SPurezza:98.87% - 99.96%Colore e forma:SolidPeso molecolare:378.46Ref: TM-T22414
1mg104,00€2mgPrezzo su richiesta5mg250,00€10mg373,00€25mg645,00€50mg938,00€100mg1.311,00€200mg1.768,00€1mL*10mM (DMSO)274,00€8-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)Formula:C8H5ClN2OPurezza:98.79%Colore e forma:SolidPeso molecolare:180.59(R)-(-)-JQ1 Enantiomer
CAS:<p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>Formula:C23H25ClN4O2SPurezza:99.38%Colore e forma:SolidPeso molecolare:456.99ICG001
CAS:ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.Formula:C33H32N4O4Purezza:99.06% - 99.95%Colore e forma:SolidPeso molecolare:548.63Ref: TM-T2237
1mg35,00€5mg70,00€10mg106,00€25mg207,00€50mg360,00€100mg558,00€500mg1.198,00€1mL*10mM (DMSO)86,00€Rucaparib hydrochloride
CAS:Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.Formula:C19H19ClFN3OColore e forma:SolidPeso molecolare:359.831,2-Dipalmitoyl-sn-glycerol
CAS:<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Formula:C35H68O5Purezza:97.84% - 99.78%Colore e forma:SolidPeso molecolare:568.91Rucaparib acetate
CAS:Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.Formula:C21H22FN3O3Colore e forma:SolidPeso molecolare:383.423AZD-2461
CAS:AZD2461 is a novel PARP inhibitor.Formula:C22H22FN3O3Purezza:98% - 99.87%Colore e forma:SolidPeso molecolare:395.43JQEZ5
CAS:JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formula:C30H38N8O2Purezza:98.14% - ≥98%Colore e forma:SolidPeso molecolare:542.685-AIQ
CAS:5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.Formula:C9H8N2OPurezza:95.95%Colore e forma:SolidPeso molecolare:160.17Amodiaquine
CAS:Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formula:C20H22ClN3OPurezza:99.78% - 99.99%Colore e forma:Crystals From Absolute Ethanol SolidPeso molecolare:355.86Ref: TM-T8381
1mg52,00€2mg70,00€5mg96,00€10mg173,00€25mg304,00€50mg452,00€100mg647,00€1mL*10mM (DMSO)120,00€XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formula:C26H30N6O3Purezza:98.21%Colore e forma:SolidPeso molecolare:474.55DMOG
CAS:<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formula:C6H9NO5Purezza:80.23% - 99.98%Colore e forma:SolidPeso molecolare:175.14EB-47 dihydrochloride
CAS:EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Formula:C24H29Cl2N9O6Colore e forma:SolidPeso molecolare:610.45Ruboxistaurin
CAS:Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.Formula:C28H28N4O3Colore e forma:SolidPeso molecolare:468.55SC-43
CAS:SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formula:C21H13ClF3N3O2Purezza:98.44%Colore e forma:SolidPeso molecolare:431.8Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purezza:99.88%Colore e forma:White Crystal Or PowderPeso molecolare:182.17MS31 trihydrochloride
MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.Formula:C20H30Cl3N3O2Colore e forma:SolidPeso molecolare:450.83Menin-MLL inhibitor 20
CAS:Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formula:C33H40N8O4Purezza:97.77%Colore e forma:SolidPeso molecolare:612.72Ref: TM-T9399
1mg40,00€5mg90,00€10mg135,00€25mg264,00€50mg390,00€100mg555,00€200mg752,00€1mL*10mM (DMSO)90,00€ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purezza:97.03% - >99.99%Colore e forma:SolidPeso molecolare:491.55Ref: TM-T4697
1mg47,00€2mg59,00€5mg96,00€10mg150,00€25mg299,00€50mg432,00€100mg527,00€200mg758,00€1mL*10mM (DMSO)96,00€Talazoparib
CAS:Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).Formula:C19H14F2N6OPurezza:97.02% - 99.92%Colore e forma:SolidPeso molecolare:380.35Ref: TM-T6253
2mg42,00€5mg62,00€10mg88,00€25mg135,00€50mg187,00€100mg311,00€200mg429,00€500mg697,00€1mL*10mM (DMSO)67,00€GeA-69
CAS:<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Formula:C20H16N2OPurezza:99.85%Colore e forma:SolidPeso molecolare:300.35YKL-06-061
CAS:YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formula:C30H37N7O2Purezza:99.52% - 99.79%Colore e forma:SolidPeso molecolare:527.66Ref: TM-T5576
1mg35,00€5mg77,00€10mg123,00€25mg188,00€50mg283,00€100mg424,00€200mg640,00€1mL*10mM (DMSO)88,00€Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14Isoxazole
CAS:Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formula:C3H3NOPurezza:99.34%Colore e forma:Colorless LiquidPeso molecolare:69.06Birabresib
CAS:Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4Formula:C25H22ClN5O2SPurezza:98.3% - 99.36%Colore e forma:SolidPeso molecolare:491.99Ref: TM-T6032
2mg48,00€5mg73,00€10mg95,00€25mg150,00€50mg235,00€100mg396,00€200mg590,00€500mg943,00€1mL*10mM (DMSO)79,00€Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurezza:99.09% - 99.91%Colore e forma:SolidPeso molecolare:323.41Ref: TM-TQ0037
1mg35,00€2mg48,00€5mg70,00€10mg111,00€25mg255,00€50mg465,00€100mg838,00€200mg1.130,00€1mL*10mM (DMSO)78,00€MT-DADMe-ImmA
CAS:MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).Formula:C13H19N5OSPurezza:99.56%Colore e forma:SolidPeso molecolare:293.39Ref: TM-TQ0008
1mg70,00€5mg135,00€10mg225,00€25mg399,00€50mg560,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)169,00€3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS:3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .Formula:C9H10N2OPurezza:99.3% - 99.64%Colore e forma:SolidPeso molecolare:162.19Ref: TM-T50006
2mg39,00€5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€500mg677,00€1mL*10mM (DMSO)59,00€Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurezza:98% - 99.45%Colore e forma:SolidPeso molecolare:393.49Ref: TM-T1825
1mg38,00€2mg49,00€5mg70,00€10mg88,00€25mg164,00€50mg224,00€100mg393,00€1mL*10mM (DMSO)70,00€TFMB-(R)-2-HG
CAS:TFMB-(R)-2-HG, a carcinogen in AML, hinders SCF ER-Hoxb8 differentiation after estrogen loss.Formula:C13H11F3O4Purezza:97.15%Colore e forma:SolidPeso molecolare:288.22Ref: TM-T17065
1mg77,00€5mg166,00€10mg250,00€25mg452,00€50mg677,00€100mg938,00€1mL*10mM (DMSO)140,00€N-Oxalylglycine
CAS:N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.Formula:C4H5NO5Purezza:99.23%Colore e forma:Colourless SolidPeso molecolare:147.09Tubacin
CAS:Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.Formula:C41H43N3O7SPurezza:97.62% - 98.75%Colore e forma:SolidPeso molecolare:721.86Alobresib
CAS:Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.Formula:C26H23N5O2Purezza:97.63%Colore e forma:SolidPeso molecolare:437.49Ref: TM-T8495
1mg73,00€2mg93,00€5mg144,00€10mg274,00€25mg535,00€50mg753,00€100mg1.035,00€1mL*10mM (DMSO)159,00€SHR0302
CAS:SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Formula:C18H22N8O2SPurezza:99.11%Colore e forma:SolidPeso molecolare:414.48Ref: TM-T9195
1mg80,00€5mg183,00€10mg298,00€25mg512,00€50mg817,00€100mg1.311,00€1mL*10mM (DMSO)167,00€Aurothiomalate sodium
CAS:<p>Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.</p>Formula:C4H3AuNa2O4SPurezza:99.66%Colore e forma:SoildPeso molecolare:390.07Ruxolitinib phosphate
CAS:<p>Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.</p>Formula:C17H21N6O4PPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:404.36BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purezza:99.82%Colore e forma:SolidPeso molecolare:413.47J-147
CAS:J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.Formula:C18H17F3N2O2Purezza:99.61% - >99.99%Colore e forma:SolidPeso molecolare:350.33Rucaparib Phosphate
CAS:<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Formula:C19H18FN3O·H3PO4Purezza:99.37%Colore e forma:SolidPeso molecolare:421.36BRD4 Inhibitor-24
CAS:<p>BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity.</p>Formula:C13H14N2O4Purezza:99.66%Colore e forma:SolidPeso molecolare:262.26Ruxolitinib (S enantiomer)
CAS:Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formula:C17H18N6Purezza:99.37% - 99.79%Colore e forma:SolidPeso molecolare:306.36BYK204165
CAS:BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)Formula:C15H12N2O2Purezza:99.61%Colore e forma:SolidPeso molecolare:252.27Ref: TM-T7896
1mg47,00€5mg70,00€10mg96,00€25mg170,00€50mg250,00€100mg369,00€200mg540,00€1mL*10mM (DMSO)77,00€XAV-939
CAS:XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).Formula:C14H11F3N2OSPurezza:97.47% - 99.67%Colore e forma:SolidPeso molecolare:312.31Momelotinib HCl
CAS:Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formula:C23H24Cl2N6O2Colore e forma:SolidPeso molecolare:487.38CBP/EP300-IN-1
CAS:<p>CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.</p>Formula:C23H23FN2O5Purezza:99.05%Colore e forma:SolidPeso molecolare:426.44TTK21
CAS:<p>TTK21 is an activator of CBP/p300 histone acetyltransferase activity.</p>Formula:C17H15ClF3NO2Purezza:98.43%Colore e forma:SolidPeso molecolare:357.75Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurezza:99.53%Colore e forma:White Crystalline SolidPeso molecolare:364.29B2
CAS:B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's diseaseFormula:C20H17ClN4O3Purezza:99.66%Colore e forma:SolidPeso molecolare:396.83BCI-121
CAS:BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Formula:C14H18BrN3O2Purezza:99.67%Colore e forma:SolidPeso molecolare:340.22C-7280948
CAS:C-7280948 is a PRMT1 inhibitor.Formula:C14H16N2O2SPurezza:99.55% - ≥95%Colore e forma:SolidPeso molecolare:276.35Ref: TM-T2097
5mg48,00€10mg70,00€25mg115,00€50mg188,00€100mg283,00€200mg437,00€500mg705,00€1mL*10mM (DMSO)52,00€(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurezza:97.57% - 99.97%Colore e forma:SolidPeso molecolare:456.99Ref: TM-T2110
1mg35,00€2mg44,00€5mg60,00€10mg79,00€25mg96,00€50mg144,00€100mg188,00€200mg283,00€500mg512,00€1mL*10mM (DMSO)66,00€WM-8014
CAS:WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.Formula:C20H17FN2O3SPurezza:99.64%Colore e forma:SolidPeso molecolare:384.42Ref: TM-T4362
1mg57,00€2mg82,00€5mg115,00€10mg170,00€25mg334,00€50mg497,00€100mg720,00€1mL*10mM (DMSO)136,00€MI-503
CAS:MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.Formula:C28H27F3N8SPurezza:99.87% - 99.99%Colore e forma:SolidPeso molecolare:564.63Ref: TM-TQ0069
1mgPrezzo su richiesta2mg115,00€5mg120,00€10mg188,00€25mg354,00€50mg588,00€100mg938,00€200mg1.406,00€1mL*10mM (DMSO)149,00€Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purezza:99.19% - 99.75%Colore e forma:SolidPeso molecolare:504.49WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formula:C16H13Br2N3O3Purezza:99.93%Colore e forma:SolidPeso molecolare:455.1Apabetalone
CAS:<p>Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery</p>Formula:C20H22N2O5Purezza:98.08% - ≥98%Colore e forma:SolidPeso molecolare:370.4DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.Formula:C21H29Cl3N4OPurezza:98%Colore e forma:SolidPeso molecolare:459.84SGC2085 HCl
CAS:SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.Formula:C19H24N2O2·HClPurezza:99.91%Colore e forma:SolidPeso molecolare:348.87Ref: TM-T4013
1mg93,00€2mg150,00€5mg190,00€10mg343,00€25mg567,00€50mg825,00€100mg1.130,00€1mL*10mM (DMSO)244,00€GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formula:C18H15N3O2Purezza:99.52%Colore e forma:SolidPeso molecolare:305.33Buformin hydrochloride
CAS:Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Formula:C6H16ClN5Purezza:97.83%Colore e forma:SolidPeso molecolare:193.68BD750
CAS:BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM inFormula:C14H13N3OSPurezza:99.02%Colore e forma:SolidPeso molecolare:271.34Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formula:C18H15N5OPurezza:97.03%Colore e forma:SolidPeso molecolare:317.34JQ-1 (carboxylic acid)
CAS:JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)Formula:C19H17ClN4O2SPurezza:99.14% - 99.9%Colore e forma:SolidPeso molecolare:400.88Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formula:C27H36N6O3SPurezza:97.31% - 99.96%Colore e forma:SolidPeso molecolare:524.68Ref: TM-T1995
1g625,00€5mg49,00€10mg69,00€50mg113,00€100mg134,00€200mg216,00€500mg472,00€1mL*10mM (DMSO)57,00€BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formula:C28H39N7O3Purezza:98% - 99.88%Colore e forma:SolidPeso molecolare:521.65Ref: TM-T6173
1mg46,00€2mg59,00€5mg87,00€10mg103,00€25mg124,00€50mg197,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)97,00€Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:469.94Ref: TM-T2638
5mg51,00€10mg88,00€25mg160,00€50mg296,00€100mg469,00€500mg1.035,00€1mL*10mM (DMSO)57,00€JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formula:C15H12F2N6O3SPurezza:99.1% - 99.85%Colore e forma:SolidPeso molecolare:394.36Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurezza:99.99%Colore e forma:SolidPeso molecolare:464.591,5-Isoquinolinediol
CAS:1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.Formula:C9H7NO2Purezza:98.29% - 99.35%Colore e forma:Of White To White PowderPeso molecolare:161.16666-15
CAS:666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.Formula:C33H31Cl2N3O5Purezza:99.41% - 99.88%Colore e forma:SolidPeso molecolare:620.52Ref: TM-T5318
1mg57,00€5mg111,00€10mg170,00€25mg344,00€50mg533,00€100mg747,00€200mg1.026,00€1mL*10mM (DMSO)154,00€Fucosterol
CAS:Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.Formula:C29H48OPurezza:98.39% - 99.68%Colore e forma:White PowderPeso molecolare:412.69M1001
CAS:M1001 is a HIF-2α agonist.Formula:C17H17N3O2SPurezza:98.83%Colore e forma:SolidPeso molecolare:327.4PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurezza:98.74% - 99.19%Colore e forma:SolidPeso molecolare:347.39Acetyl Pentapeptide-1 acetate
Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.Formula:C34H55N9O12Purezza:99.09%Colore e forma:SolidPeso molecolare:781.86AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurezza:97.24% - 99.83%Colore e forma:SolidPeso molecolare:379.48TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Formula:C31H31ClFN7O2Purezza:98.49% - 99.62%Colore e forma:SolidPeso molecolare:588.07A1874
CAS:<p>A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.</p>Formula:C58H62Cl3F2N9O7SPurezza:99.52%Colore e forma:SolidPeso molecolare:1173.59Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Formula:C19H20N4O·C7H8O3SPurezza:99.34% - 99.87%Colore e forma:SolidPeso molecolare:492.59WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purezza:98% - 99.67%Colore e forma:SolidPeso molecolare:376.22-hexyl-4-Pentynoic Acid
CAS:2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Formula:C11H18O2Purezza:98%Colore e forma:SolidPeso molecolare:182.26Pyridone 6
CAS:Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).Formula:C18H16FN3OPurezza:97.1% - 98.74%Colore e forma:SolidPeso molecolare:309.34Ref: TM-T3080
1mg52,00€2mg74,00€5mg111,00€10mg183,00€25mg378,00€50mg620,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)116,00€Aurora kinase inhibitor-2
CAS:Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).Formula:C23H20N4O3Purezza:98.66%Colore e forma:SolidPeso molecolare:400.43Ref: TM-T9040
1mg66,00€5mg145,00€10mg212,00€25mg380,00€50mg562,00€100mg832,00€200mg1.121,00€1mL*10mM (DMSO)159,00€Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColore e forma:SolidPeso molecolare:237.21MRTX9768
CAS:MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.Formula:C24H17FN6OPurezza:97.02%Colore e forma:SolidPeso molecolare:424.43BAZ1A-IN-1
CAS:BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.Formula:C16H12N4O3SPurezza:99.87%Colore e forma:SolidPeso molecolare:340.36Ref: TM-T9552
1mg88,00€5mg187,00€10mg283,00€25mg567,00€50mg848,00€100mg1.159,00€200mg1.549,00€1mL*10mM (DMSO)207,00€I-CBP112
CAS:I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.Formula:C27H36N2O5Purezza:98.18%Colore e forma:SolidPeso molecolare:468.59Ref: TM-T3969
1mg34,00€2mg52,00€5mg97,00€10mg170,00€25mg313,00€50mg449,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)97,00€
