Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2409 prodotti di "Cromatina/Epigenetica"
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Miltefosine
CAS:<p>Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.</p>Formula:C21H46NO4PPurezza:98% - 99.87%Colore e forma:White To Off-White PowderPeso molecolare:407.57Hydralazine hydrochloride
CAS:Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Formula:C8H9ClN4Purezza:99.85% - 99.86%Colore e forma:Yellow Crystals White Crystalline SolidPeso molecolare:196.64MS417
CAS:MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weakFormula:C20H19ClN4O2SPurezza:99.87%Colore e forma:SolidPeso molecolare:414.91A-485
CAS:<p>A-485 is a p300/CBP histone acetyltransferase (HAT) inhibitor that inhibits p300 and CBP. A-485 has antitumor effects. Cost effective and quality assured.</p>Formula:C25H24F4N4O5Purezza:98.01% - 99.44%Colore e forma:SolidPeso molecolare:536.48ZL0580
CAS:ZL0580 suppresses HIV by blocking Tat activation, halting transcription, and promoting repressive chromatin at the HIV promoter.Formula:C25H23F3N4O4SPurezza:99.70%Colore e forma:SolidPeso molecolare:532.53Brepocitinib P-Tosylate
CAS:<p>Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).</p>Formula:C25H29F2N7O4SPurezza:99.82% - 99.97%Colore e forma:SolidPeso molecolare:561.6SNDX-5613
CAS:Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurezza:99.12% - 99.74%Colore e forma:SolidPeso molecolare:630.82MAT2A inhibitor 2
CAS:<p>MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).</p>Formula:C18H24ClN3O3Purezza:99.52%Colore e forma:SolidPeso molecolare:365.85Bufexamac
CAS:Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.Formula:C12H17NO3Purezza:99.73%Colore e forma:Acicular CrystalPeso molecolare:223.27Diflunisal
CAS:Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.Formula:C13H8F2O3Purezza:98.92% - 99.42%Colore e forma:SolidPeso molecolare:250.20Nicotinamide riboside
CAS:<p>Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-</p>Formula:C11H15N2O5Purezza:98.82% - 99.58%Colore e forma:SolidPeso molecolare:255.25WDR5-IN-6
CAS:WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6Formula:C13H8Cl2N2O2SPurezza:99.69%Colore e forma:SoildPeso molecolare:327.19NU6140
CAS:<p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>Formula:C23H30N6O2Purezza:98.33%Colore e forma:SolidPeso molecolare:422.52Tulmimetostat
CAS:Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advancedFormula:C28H36ClN3O5SPurezza:98.04% - 99.872%Colore e forma:SolidPeso molecolare:562.12GNE-781
CAS:GNE-781: potent CBP inhibitor (IC50: 0.94 nM), also targets BRET/BRD4(1) (IC50: 6.2/5100 nM).Formula:C27H33F2N7O2Purezza:99.25% - 99.64%Colore e forma:SolidPeso molecolare:525.59Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formula:C6H13NO5·HClPurezza:99.77%Colore e forma:White Solid CrystallinePeso molecolare:215.63A-395
CAS:<p>A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.</p>Formula:C26H35FN4O2SPurezza:98.43%Colore e forma:SolidPeso molecolare:486.65Tranylcypromine (2-PCPA) hydrochloride
CAS:<p>Tranylcypromine (2-PCPA) HCl, a MAO inhibitor, treats major, dysthymic, and atypical depression.</p>Formula:C9H11N·HClPurezza:99.48% - 99.86%Colore e forma:SolidPeso molecolare:169.66Ilginatinib hydrochloride
CAS:Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H21ClFN7Purezza:99.55%Colore e forma:SolidPeso molecolare:425.89iso-Azalansta
CAS:(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study of cardiovascular disease.Formula:C22H24ClN3O2SPurezza:99.53% - 99.89%Colore e forma:SoildPeso molecolare:429.96(R)-CR8
CAS:<p>(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.</p>Formula:C24H29N7OPurezza:98.41%Colore e forma:SolidPeso molecolare:431.53SMARCA-BD ligand 1 for Protac
CAS:<p>SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2</p>Formula:C14H17N5OPurezza:99.93%Colore e forma:SolidPeso molecolare:271.32L-2-Hydroxyglutaric acid disodium
CAS:L-2-Hydroxyglutaric acid disodium may affect epigenetics and contribute to renal cancer, inhibiting Mi-CK (Km 2.52 mM, Ki 11.13 mM).Formula:C5H6Na2O5Purezza:99.92%Colore e forma:SolidPeso molecolare:192.08DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Formula:C25H25N3OPurezza:98.95%Colore e forma:SolidPeso molecolare:383.49ZEN-3694
CAS:ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and canFormula:C19H19N5OPurezza:98.94% - 99.76%Colore e forma:SolidPeso molecolare:333.39BMS-986158
CAS:<p>BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.</p>Formula:C30H33N5O2Purezza:98.78%Colore e forma:SolidPeso molecolare:495.62LIN28 inhibitor LI71
CAS:<p>LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.</p>Formula:C21H21NO3Purezza:95.88%Colore e forma:SolidPeso molecolare:335.4ODM-207
CAS:ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.Formula:C22H21N3O3Purezza:99.75%Colore e forma:SolidPeso molecolare:375.42EHP-101
CAS:<p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>Formula:C28H35NO3Purezza:98.36%Colore e forma:SolidPeso molecolare:433.58TAK-901
CAS:<p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>Formula:C28H32N4O3SPurezza:99.02% - 99.59%Colore e forma:SolidPeso molecolare:504.64Levetiracetam
CAS:Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onsetFormula:C8H14N2O2Purezza:99.67% - 99.86%Colore e forma:White Crystalline PowderPeso molecolare:170.21MAK683
CAS:MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).Formula:C20H17FN6OPurezza:98.25% - 99.92%Colore e forma:SolidPeso molecolare:376.39VTP50469
CAS:VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurezza:98.31% - 99.55%Colore e forma:SolidPeso molecolare:630.82Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formula:C8H6N2S3Purezza:98.79% - 99.77%Colore e forma:SolidPeso molecolare:226.34Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purezza:99.28% - >99.99%Colore e forma:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecolare:493.94MS402
CAS:MS402 is a novel BD1-selective BET BrD inhibitor.Formula:C20H19ClN2O3Purezza:99.72%Colore e forma:SolidPeso molecolare:370.83Golidocitinib
CAS:Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Formula:C25H31N9O2Purezza:98.87% - 99.88%Colore e forma:SolidPeso molecolare:489.57Pulrodemstat benzenesulfonate
CAS:Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally inhibitor of lysine specific demethylase-1 (LSD1) with anticancer effect.Formula:C30H29F2N5O5SPurezza:97.67%Colore e forma:SolidPeso molecolare:609.64Fenbendazole
CAS:Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.Formula:C15H13N3O2SPurezza:99.74%Colore e forma:White To Yellowish PowderPeso molecolare:299.35PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purezza:95.42%Colore e forma:SoildN-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formula:C25H28ClNOPurezza:99.15%Colore e forma:SolidPeso molecolare:393.95FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formula:C15H13ClFNPurezza:98.3% - 99.17%Colore e forma:SolidPeso molecolare:261.72TRIM24/BRPF1-IN-2
CAS:<p>TRIM24/BRPF1-IN-2 is a TRIM24/BRPF1 dual inhibitor with anticancer activity that inhibits the proliferation of prostate cancer cells.</p>Formula:C20H22N2O4SPurezza:98.69% - 99.13%Colore e forma:SoildPeso molecolare:386.47PT2399
CAS:PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.Formula:C17H10F5NO4SPurezza:98.8% - 99.45%Colore e forma:SolidPeso molecolare:419.32Lin28-let-7a antagonist 1
CAS:Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.Formula:C31H29N5O7Purezza:99.44%Colore e forma:SolidPeso molecolare:583.59JAK2 Inhibitor V
CAS:<p>JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.</p>Formula:C23H24N2OPurezza:98.36% - 99.15%Colore e forma:SolidPeso molecolare:344.45Chitosan oligosaccharide
CAS:Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine.Formula:C12H24N2O9Purezza:98%Colore e forma:SolidPeso molecolare:340.327Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurezza:99.59%Colore e forma:White SolidPeso molecolare:214.22Uzansertib phosphate
CAS:Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.Formula:C26H29F3N5O7PPurezza:99.75% - 99.79%Colore e forma:SolidPeso molecolare:611.51N6-Cyclohexyladenosine
CAS:N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm.Formula:C16H23N5O4Purezza:99.92% - 99.98%Colore e forma:SolidPeso molecolare:349.38
