Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2588 prodotti di "Cromatina/Epigenetica"
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MAT2A-IN-6
CAS:MAT2A-IN-6 inhibits MAT2A, may slow MTAP-deficient cancer cell growth, has research value in cancer.Formula:C18H13ClF3N3O3Colore e forma:SolidPeso molecolare:411.76MZ-242
CAS:MZ-242 is an effective and selective inhibitor of Sirt2.Formula:C24H27N7O3S2Purezza:98%Colore e forma:SolidPeso molecolare:525.65DM-NOFD
CAS:DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formula:C13H15NO5Colore e forma:SolidPeso molecolare:265.26KDOAM-25
CAS:KDOAM-25, a potent KDM5 inhibitor, enhances H3K4 methylation, hampers MM1S cell growth; IC50: 71 nM (5A), 19 nM (5B), 69 nM (5C/D).Formula:C15H25N5O2Purezza:98%Colore e forma:SolidPeso molecolare:307.39ZL0516
CAS:ZL0516, a chromone-based oral BRD4 BD1 inhibitor, shows potent in vivo efficacy and good pharmacokinetics, suggesting use in treating inflammation.Formula:C27H34N2O6Colore e forma:SolidPeso molecolare:482.57Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Colore e forma:SolidPeso molecolare:435.86CypD inhibitor C-9
CAS:CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.Formula:C22H22N4O4S2Colore e forma:SolidPeso molecolare:470.56dWIZ-1
CAS:dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).Formula:C22H29N3O4Purezza:92.87% - 92.87%Colore e forma:SolidPeso molecolare:399.48CAY10722
CAS:CAY10722 is a SIRT3 inhibitor, affecting metabolism and cancer cell survival; varying impacts on esophageal and breast cancer.Formula:C21H14Cl2N2O2Colore e forma:SolidPeso molecolare:397.254-iodo-SAHA
CAS:4-Iodo-SAHA (1k), an oral HDAC inhibitor for cancer research, has EC50s from 0.12 to 1.3 μM across various cell lines.Formula:C14H19IN2O3Colore e forma:SolidPeso molecolare:390.22SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formula:C27H24N4O4Colore e forma:SolidPeso molecolare:468.5JAK-IN-20
CAS:JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Formula:C28H30FN7O2Colore e forma:SolidPeso molecolare:515.58Peficitinib hydrochloride
CAS:Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Formula:C18H23ClN4O2Colore e forma:SolidPeso molecolare:362.86Sirt2-IN-6
CAS:Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.Formula:C26H26N6O3SColore e forma:SolidPeso molecolare:502.59ZYJ-25e
CAS:ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formula:C30H40N4O8Purezza:98%Colore e forma:SolidPeso molecolare:584.66SPV106
CAS:SPV106 is a ligand of lysine acetyltransferases (KATs).Formula:C22H40O4Purezza:98%Colore e forma:SolidPeso molecolare:368.55BIX-01338 hydrate
CAS:BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.Formula:C32H26F3N3O7Purezza:98%Colore e forma:SolidPeso molecolare:621.56HDAC3 Inhibitor
CAS:HDAC3 inhibitor: allosteric, Ki=0.16 nM, favors HDAC3 over HDAC1/2, targets specific leukemia cells, EC50=36.37-151.7 nM.Formula:C20H23N3O2Colore e forma:SolidPeso molecolare:337.42GW-841819X
CAS:GW841819X: (+)-JQ1 analogue, BET bromodomain inhibitor, active in vivo against various cancers.Formula:C25H21N5O2Colore e forma:SolidPeso molecolare:423.47Dot1L-IN-2
CAS:Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectivelyFormula:C27H24N8OPurezza:98%Colore e forma:SolidPeso molecolare:476.53
