Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2579 prodotti di "Cromatina/Epigenetica"
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MAT2A-IN-6
CAS:MAT2A-IN-6 inhibits MAT2A, may slow MTAP-deficient cancer cell growth, has research value in cancer.Formula:C18H13ClF3N3O3Colore e forma:SolidPeso molecolare:411.76NL-103
CAS:NL-103, a dual-targeting compound, inhibits HDACs & Hh pathway, countering vismodegib-resistant Smo mutations.Formula:C26H27Cl2N5O4Colore e forma:SolidPeso molecolare:544.43EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Formula:C20H22ClN7OPurezza:99.95%Colore e forma:SolidPeso molecolare:411.89MZ-242
CAS:MZ-242 is an effective and selective inhibitor of Sirt2.Formula:C24H27N7O3S2Purezza:98%Colore e forma:SolidPeso molecolare:525.65KDOAM-25
CAS:KDOAM-25, a potent KDM5 inhibitor, enhances H3K4 methylation, hampers MM1S cell growth; IC50: 71 nM (5A), 19 nM (5B), 69 nM (5C/D).Formula:C15H25N5O2Purezza:98%Colore e forma:SolidPeso molecolare:307.39JJO-1
CAS:JJO-1 is a bi-quinoline activating all AMPK αβγ isoforms except γ3; it requires low ATP and is unaffected by γ mutations or β deletions.Formula:C19H13N3Colore e forma:SolidPeso molecolare:283.33Fagaronine chloride
CAS:Fagaronine chloride is a potent inhibitor of Topoisomerases I.Formula:C21H20ClNO4Colore e forma:SolidPeso molecolare:385.84CPI-4203
CAS:CPI-4203 is a selective inhibitor of KDM5 demethylases.Formula:C16H14N4OColore e forma:SolidPeso molecolare:278.31Lobelane Hydrochloride
CAS:Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Formula:C22H30ClNColore e forma:SolidPeso molecolare:343.93Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Colore e forma:SolidPeso molecolare:435.86CypD inhibitor C-9
CAS:CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.Formula:C22H22N4O4S2Colore e forma:SolidPeso molecolare:470.564-iodo-SAHA
CAS:4-Iodo-SAHA (1k), an oral HDAC inhibitor for cancer research, has EC50s from 0.12 to 1.3 μM across various cell lines.Formula:C14H19IN2O3Colore e forma:SolidPeso molecolare:390.22DM-NOFD
CAS:DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formula:C13H15NO5Colore e forma:SolidPeso molecolare:265.26JAK-IN-20
CAS:JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Formula:C28H30FN7O2Colore e forma:SolidPeso molecolare:515.58ZL0516
CAS:ZL0516, a chromone-based oral BRD4 BD1 inhibitor, shows potent in vivo efficacy and good pharmacokinetics, suggesting use in treating inflammation.Formula:C27H34N2O6Colore e forma:SolidPeso molecolare:482.57HDAC6-IN-11
CAS:HDAC6-IN-11 (Compound 9) is a cancer cell growth blocker, selectively inhibiting HDAC6 (>300-fold) with an IC50 of 20.7 nM.Formula:C19H16N2O4Colore e forma:SolidPeso molecolare:336.34Peficitinib hydrochloride
CAS:Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Formula:C18H23ClN4O2Colore e forma:SolidPeso molecolare:362.86SirReal-1
CAS:SirReal-1 is an effective and selective inhibitor of Sirt2.Formula:C18H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:370.49Prospasmine
CAS:Prospasmine is an anticholinergic.Formula:C17H28ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:313.87Sirt2-IN-6
CAS:Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.Formula:C26H26N6O3SColore e forma:SolidPeso molecolare:502.59
