Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2575 prodotti di "Cromatina/Epigenetica"
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1,2,3,4,5,6-Hexabromocyclohexane
CAS:Inhibits JAK2 autophosphorylation; non-cytotoxic at 100μM; 1μM reduces activity by 50%, 50μM nearly abolishes it.Formula:C6H6Br6Purezza:98%Colore e forma:SolidPeso molecolare:557.54Tankyrase-IN-2
CAS:Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFormula:C17H14F2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:316.36(5H)-Phenanthridinone
CAS:6(5H)-Phenanthridinone suppresses PARP1/2, reduces RDM4 cell growth, downregulates pro-inflammatory genes, and alleviates EAE symptoms in rats.Formula:C13H9NOColore e forma:SolidPeso molecolare:195.22NCC-149
CAS:NCC-149 is a HDAC8 inhibitor.Formula:C16H14N4O2SColore e forma:SolidPeso molecolare:326.37MS-1020
CAS:MS-1020 inhibits JAK3/STAT3, blocks active JAK3, suppresses JAK3/STAT5 signaling, and targets STAT3 in certain cells.Formula:C21H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:346.38AC-93253 iodide
CAS:AC-93253 iodide is a selective inhibitor of SIRT2. It significantly enhances the acetylation of tubulin p53 and histone H4.Formula:C23H25IN2SPurezza:98%Colore e forma:SolidPeso molecolare:488.43Ac-Lys-AMC
CAS:Ac-Lys-AMC (Hexanamide) is a fluorescent substrate for histone deacetylase HDACs.Formula:C18H23N3O4Purezza:98%Colore e forma:SolidPeso molecolare:345.39Bromodomain inhibitor-9
CAS:Bromodomain inhibitor-9 selectively targets BRD4-1 (Kd 12 nM), used in metabolic, inflammatory, fibrotic, and autoimmune disease studies.Formula:C24H28N4O5SColore e forma:SolidPeso molecolare:484.57ZYJ-34v
CAS:ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formula:C27H35N3O6Purezza:98%Colore e forma:SolidPeso molecolare:497.58CPI-455 HCl
CAS:CPI-455: specific KDM5A inhibitor, IC50=10±1nM, increases H3K4me3, reduces DTPs in cancer cells.Formula:C16H15ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:314.77HDAC-IN-5
CAS:HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.Formula:C26H24F3N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:527.56ZL0454
CAS:ZL0454 is an effective and selective Bromodomain-containing protein 4 inhibitors (IC50: 49 and 32 nM for BD1 and BD2).Formula:C18H22N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:374.46GNE-272
CAS:GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.Formula:C22H25FN6O2Colore e forma:SolidPeso molecolare:424.47SD-1029
CAS:SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.Formula:C25H32Br2Cl2N2O3Colore e forma:SolidPeso molecolare:639.25Jaspamycin
CAS:Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Formula:C12H12N4O5Colore e forma:SolidPeso molecolare:292.25(R)-UT-155
CAS:(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.Formula:C20H15F4N3O2Colore e forma:SolidPeso molecolare:405.35PB131
CAS:PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitableFormula:C16H16FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:301.32ARTD10/PARP10-IN-1
CAS:ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Formula:C12H12N2O4Purezza:99.14%Colore e forma:SolidPeso molecolare:248.23MPT0G211
CAS:MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.Formula:C17H15N3O2Purezza:99.93% - 99.98%Colore e forma:SolidPeso molecolare:293.32Ref: TM-T60616
1mg92,00€5mg222,00€10mg356,00€25mg560,00€50mg782,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)245,00€Exifone
CAS:Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increasedFormula:C13H10O7Purezza:99.77% - 99.95%Colore e forma:Yellow SolidPeso molecolare:278.21
