Recettore della prostaglandina

BGC201531 is a EP4 antagonist for the treatment of acute migraine.

Aganepag is a potent Prostanoid EP2 receptor agonist, with an EC50 of 0.19 nM. It …

Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is …

Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 …

Omidenepag is a pharmacologically active form of Omidenepag Isopropyl and is a selective, non-prostanoid EP2 …

Evatanepag is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation …

Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal …

Tiaprost is a analog of prostaglandin F2α .

Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase …

L-798106 is a highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM). It also has micromolar …

KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 …

Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.

TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold …

BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 …

Treprostinil is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).

AM211 is a potent and orally bioavailable antagonist of prostaglandin D2 (PGD2) receptor type 2 …

Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist (Ki: 0.44 nM). It exhibited …

Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities.

BGC201531 hydrochloride is a EP4 antagonist for the treatment of acute migraine.

mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .

ONO-8130 is an orally available antagonist of EP1 receptor.

L-902688 is an orally active EP4 receptor agonist (Ki: 0.38 nM; EC50: 0.6 nM). L-902688 …

Oxysophocarpine is extracted from Sophra flavescens Ait.

ONO-AE3-208 is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer.

Ethamsylate usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet …

Treprostinil is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).

Dazoxiben is a potent inhibitor of thromboxane (TX) synthase

Grapiprant is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog …

Furprofen acts via the inhibition of prostaglandin (PGE) synthesis. Furprofen can be treated orally for …

Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of …

Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and …

AH 6809 is an antagonist of EP and DP receptor(with Kis of 1217, 1150, 1597, …

E7046 is a specific, orally bioavailable EP4 antagonist (IC50: 13.5 nM, Ki: 23.14 nM), exhibiting …

Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A …

Taprenepag isopropyl is a highly selective agonist of the EP2 receptor.

AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).

Rutin, a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic …

Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) …

PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is …

L-161982 is a selective EP4 receptor antagonist. L-161982 decreases collagen-induced arthritis in mice. L-161982 fully …

Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F2α and it can effectively promote …

16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It …

Travoprost is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin …

Evodiamine, an indole alkaloid found in Evodia rutaescarpa, acts as an anti-inflammatory compound.

Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct …

Bimatoprost is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment …

Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities, it plays protective role in sepsis-induced acute lung injury, …

Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.

Ermanin shows anti-inflammatory activity by suppressing the iNOS and COX-2 expression. Ermanin may have anti-HIV-1activity. …

(+)-Talarozole is a potent retinoic acid metabolism inhibitor .

Taraxerol can be used as a lipid biomarker for mangrove input to the SE Atlantic.

Pranoprofen (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.

Taprenepag (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM). …

Benorylate is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic …

EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6.1 nM …

2-Acetylbenzoic acid is more potent than 2-propionyloxybenzoic acid in inhibiting platelet function and platelet prostaglandin …

Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as …

Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, …

3-O-Acetyl-α-boswellic acid has strong anti-inflammatory activity.

Alprostadil is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. …

MRE-269 is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269 is used for …

Cloprostenol sodium is a more water solute, crystalline form of cloprostenol than the free acid, …

7-demethylsuberosin is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory …

PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). …

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer. It can maintain the content …