Enzima
Gli inibitori enzimatici sono molecole che si legano agli enzimi e ne diminuiscono l'attività. Questi inibitori sono ampiamente utilizzati nella ricerca per studiare la cinetica enzimatica, la regolazione e il ruolo di specifici enzimi nelle vie metaboliche. Gli inibitori enzimatici sono anche fondamentali nello sviluppo di farmaci, poiché molti agenti terapeutici agiscono inibendo enzimi coinvolti in processi patologici. Mirando agli enzimi, questi inibitori possono modulare le vie biochimiche e offrire potenziali trattamenti per varie malattie. Presso CymitQuimica, offriamo una vasta selezione di inibitori enzimatici di alta qualità per supportare le tue ricerche in biochimica, farmacologia e scoperta di farmaci.
Sottocategorie di "Enzima"
- Anidrasi carbonica(195 prodotti)
- Idrossilasi(35 prodotti)
- MPO(2 prodotti)
- Riduttasi(50 prodotti)
- Tirosinasi(71 prodotti)
Trovati 3616 prodotti di "Enzima"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Formula:C29H31N5O5SPurezza:99.28%Colore e forma:SolidPeso molecolare:561.654-Chlorosalicylic acid
CAS:<p>4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) is antimicrobial compositions comprising a metal salt and a benzoic acid analog</p>Formula:C7H5ClO3Purezza:98.59%Colore e forma:Off-White To Light Beige PowderPeso molecolare:172.57Actarit
CAS:Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.Formula:C10H11NO3Purezza:99.64% - 99.74%Colore e forma:White Or Off-White Crystal Or Crystalline SolidPeso molecolare:193.2Topiramate
CAS:<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formula:C12H21NO8SPurezza:99.79% - 99.92%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:339.36Brinzolamide
CAS:Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Formula:C12H21N3O5S3Purezza:99.84% - >99.99%Colore e forma:Crystalline SolidPeso molecolare:383.51Methazolamide
CAS:Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Formula:C5H8N4O3S2Purezza:99.31% - 99.77%Colore e forma:Crystals From Water SolidPeso molecolare:236.27Fenclonine
CAS:Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H10ClNO2Purezza:98.81% - >99.99%Colore e forma:Crystals From Methanol White SolidPeso molecolare:199.63Tioxolone
CAS:Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Formula:C7H4O3SPurezza:97.79%Colore e forma:Light Yellow To Beige PowderPeso molecolare:168.17pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Formula:C6H6NO6PPurezza:99.82%Colore e forma:SolidPeso molecolare:219.09Zonisamide
CAS:Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Formula:C8H8N2O3SPurezza:99.05% - 99.9%Colore e forma:Off-White PowderPeso molecolare:212.23Telotristat ethyl
CAS:Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Formula:C27H26ClF3N6O3Purezza:98% - 99.89%Colore e forma:White SolidPeso molecolare:574.98Arbutin
CAS:Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.Formula:C12H16O7Purezza:99.58% - 99.93%Colore e forma:Colorless Elongated Prisms From Moist Ethyl Acetate White PowderPeso molecolare:272.255-Feruloylquinic acid
CAS:5-Feruloylquinic acid, a potent Sirt1 activator, may aid in developing anti-aging drugs.Formula:C17H20O9Purezza:99.03%Colore e forma:SolidPeso molecolare:368.34p-Ethynylphenylalanine hydrochloride
CAS:p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Formula:C11H12ClNO2Purezza:99.03%Colore e forma:SolidPeso molecolare:225.67Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formula:C11H15NO5Purezza:99.96%Colore e forma:Crystals From Benzene SolidPeso molecolare:241.24Benzthiazide
CAS:<p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>Formula:C15H14ClN3O4S3Purezza:99.34% - 99.79%Colore e forma:Crystals From Acetone SolidPeso molecolare:431.94Acipimox
CAS:Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.Formula:C6H6N2O3Purezza:98.98%Colore e forma:Low Yellow Liquid Or CrystallinePeso molecolare:154.12Flanvotumab
CAS:Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Purezza:> 95%Colore e forma:LiquidPeso molecolare:145.42 kDaACT-678689
CAS:ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].Formula:C23H22ClFN6O4S2Purezza:99.46%Colore e forma:SolidPeso molecolare:565.04Ref: TM-T14119
1mg113,00€5mg259,00€10mg393,00€25mg655,00€50mg905,00€100mg1.216,00€200mg1.634,00€1mL*10mM (DMSO)324,00€TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formula:C21H18N6O4SColore e forma:SolidPeso molecolare:450.47KRAS Protein, Human, Recombinant (G12C, His)
KRAS Protein, Human, Recombinant (G12C, His) is expressed in E.Purezza:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Colore e forma:Lyophilized PowderPeso molecolare:26 KDa (reducing condition)Ref: TM-TMPJ-00510
1mg1.205,00€5µg44,00€10µg59,00€20µg95,00€50µg166,00€100µg259,00€200µg409,00€500µg800,00€hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formula:C13H10FN3O4Peso molecolare:291.06553hCAI/II/IV-IN-28
CAS:<p>hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.</p>Formula:C14H15N3O3SPurezza:96.48%Colore e forma:SolidPeso molecolare:305.35Carbonic anhydrase inhibitor 15
Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].Formula:C27H33N5O2S2Purezza:98%Colore e forma:SolidPeso molecolare:523.71SH7s
SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.Formula:C24H19ClF3N5O4SColore e forma:SolidPeso molecolare:565.95hCA XII-IN-6
<p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>Formula:C11H9N5O3S2Purezza:98%Colore e forma:SolidPeso molecolare:323.35hCAXII-IN-7
hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.Formula:C26H25N5O6S2Purezza:98%Colore e forma:SolidPeso molecolare:567.64Carbonic anhydrase
CAS:<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Colore e forma:SolidTyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Colore e forma:Odour SolidThrombopoietin Protein, Mouse, Recombinant
Expression system: E. coli<br>Length: 22-195, Partial<br>Activity: Cell ActivityColore e forma:Lyophilized PowderPeso molecolare:18.7 kDa (Predicted)hCA/VEGFR-2-IN-1
hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (Formula:C21H17FN6O3SPurezza:98%Colore e forma:SolidPeso molecolare:452.46(E)-Dehydrodiconiferyl alcohol
CAS:(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.Formula:C20H22O6Colore e forma:SolidPeso molecolare:358.39α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formula:C25H22N6OS2Colore e forma:SolidPeso molecolare:486.61Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purezza:98% - >99.99%Colore e forma:Crystals From Dioxane SolidPeso molecolare:421.41Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Formula:C23H22FN3O5SColore e forma:SolidPeso molecolare:471.12642hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Formula:C16H14F3N3O4SColore e forma:SolidPeso molecolare:401.36hTYR/AbTYR-IN-1
CAS:hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.Formula:C18H20N2O3Purezza:99.73%Colore e forma:SoildPeso molecolare:312.36hCAIX/VII-IN-1
hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.Formula:C16H13BFN3O3Purezza:98%Colore e forma:SolidPeso molecolare:325.1Tyrosinase-IN-15
Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].Purezza:98%Colore e forma:Odour SolidTyrosinase-IN-19
Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals andPurezza:98%Colore e forma:Odour SolidTyrosinase-IN-13
Tyrosinase-IN-13 (compound 3c), stemming from Flurbiprofen, acts as a potent non-competitive inhibitor of tyrosinase, exhibiting IC50 and Ki values of 68 μM andFormula:C23H18ClFN4OSPurezza:98%Colore e forma:SolidPeso molecolare:452.93Dorzolamide
CAS:<p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>Formula:C10H16N2O4S3Purezza:98%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:324.44ATP2A2 Protein, Human, Recombinant (C-His)
ATP2A2 Protein, Human, Recombinant (C-His) is expressed in E.Purezza:95%Colore e forma:SoildPeso molecolare:55.2 kDa (Predicted)Ref: TM-TMPH-03766
1mg1.813,00€5µg94,00€10µg136,00€20µg216,00€50µg324,00€100µg441,00€200µg671,00€500µg1.195,00€CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formula:C15H17N3O4SPurezza:99.07%Colore e forma:SolidPeso molecolare:335.38Carbonic anhydrase inhibitor 31
Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.Formula:C24H20N6O5SColore e forma:SolidPeso molecolare:504.12159DOTA-XYIMSR-01
CAS:DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formula:C61H88N16O22S2Colore e forma:SolidPeso molecolare:1461.57hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Formula:C19H18N2O3SColore e forma:SolidPeso molecolare:354.42Carbonic anhydrase inhibitor 26
Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.Formula:C17H14N6O4Colore e forma:SolidPeso molecolare:366.33Pyridine-2-aldoxime methochloride
CAS:Formula:C7H9N2O·ClPurezza:≥ 98.0%Colore e forma:White to off-white or light yellow crystalline powderPeso molecolare:172.61Diaminopropionoyl tripeptide-33
CAS:Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].Formula:C17H27N7O6Purezza:98%Colore e forma:SolidPeso molecolare:425.44hCAIX/XII-IN-9
hCAIX/XII-IN-9 (compound 8) is a potent inhibitor of carbonic anhydrase (CA), with Ki values of 1658 nM for hCA I, 184.8 nM for hCA II, 8.9 nM for hCA IX, and 64.8 nM for hCA XII.Formula:C26H25N5O5S2Peso molecolare:551.12971hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Formula:C24H17Cl2N3O3S2Colore e forma:SolidPeso molecolare:530.446hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5Tyrosinase-IN-21
Tyrosinase-IN-21 (compound 3g) is a tyrosinase inhibitor with an IC50 value of 80.93 μM.Formula:C23H20N4O3S2Peso molecolare:464.09768Glucose Oxidase
CAS:Purezza:≥ 100U/mgColore e forma:Pale yellow to dark yellow powderPeso molecolare:-hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5Carbonic anhydrase inhibitor 24
Carbonic anhydrase inhibitor24 (Compound 11) is an inhibitor of human carbonic anhydrase. It exhibits Ki values of 10.7 nM and 7.5 nM against hCAs IX and XII, respectively.Formula:C16H14Cl2N2O6SPeso molecolare:431.99496Carbonic anhydrase inhibitor 21
Compound 5h, known as Carbonic anhydrase inhibitor 21, is a specific inhibitor of carbonic anhydrase (hCA IX) with a K\(_i\) of 15.1 nM, demonstrating high selectivity compared to other isoforms studied. This compound is utilized in anticancer research.Formula:C32H48N4O10P2S2Peso molecolare:774.22871hCAXII-IN-9
hCAXII-IN-9 (Compound 3I) is a selective hCAXII inhibitor with Ki values of 28 nM for hCAXII, 7192.6 nM for hCAI, 188.6 nM for hCAII, and greater than 100000 nM for hCAIX. This compound may be utilized in anti-tumor research.Formula:C24H30N3O7PSPeso molecolare:535.15421CA Ⅱ-IN-1
CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.Formula:C18H19NO6SColore e forma:SolidPeso molecolare:377.41Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formula:C4H5NO4SColore e forma:SolidPeso molecolare:163.15Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColore e forma:SolidPeso molecolare:429.7AV22-149
AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .Formula:C23H28F3N3O6S2Colore e forma:SolidPeso molecolare:563.61β-Glucosidase, from almonds
CAS:Purezza:approx. 90% (biuret)Colore e forma:White to pale yellow or beige powderPeso molecolare:-Swertiajaponin
CAS:Swertiajaponin possesses antimicrobial activity.Formula:C22H22O11Purezza:99.85%Colore e forma:SolidPeso molecolare:462.4GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Formula:C88H126F3N6NaO24S4Peso molecolare:1858.75561hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Colore e forma:Odour SolidhCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Formula:C24H28N6O6SPurezza:98%Colore e forma:SolidPeso molecolare:528.582-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formula:C10H14O2Colore e forma:SolidPeso molecolare:166.22Chlorthalidone Impurity G
CAS:Chlorthalidone impurity G, a thiazide-like diuretic's contaminant, has mild antihypertensive properties and inhibits several carbonic anhydrase isoforms.Formula:C14H9Cl2NO2Colore e forma:SolidPeso molecolare:294.13L-Lactate Dehydrogenase from bovine heart, powder, approx. 300 U/mg
CAS:Colore e forma:Lyophilised powderhCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFormula:C23H26N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:498.55hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Formula:C22H23FN6O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.52α-Amylase (with starch)
CAS:Purezza:≥ 600U/gColore e forma:White to beige or pale yellow-brown powderα-Pyrone
CAS:<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Formula:C5H4O2Colore e forma:SolidPeso molecolare:96.08Invertase, from Saccharomyces cerevisiae
CAS:Colore e forma:White to faint-yellow or light-brown powderhCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFormula:C17H14N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:382.4Tyrosinase-IN-14
<p>Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity</p>Formula:C21H13Br2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:547.22Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Colore e forma:LiquidPeso molecolare:145.55 kDaCA inhibitor 2
<p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>Formula:C7H9N7O3S3Purezza:98%Colore e forma:SolidPeso molecolare:335.39TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Formula:C35H51N3O3Colore e forma:SolidPeso molecolare:561.798(Iso)-Samixogrel
CAS:(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Formula:C25H25ClN2O4SPurezza:98.85%Colore e forma:SolidPeso molecolare:484.99Potassium iodide
CAS:Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。Formula:IKColore e forma:White Solid CrystallinePeso molecolare:166.01hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formula:C22H20N4O6S2Colore e forma:SolidPeso molecolare:500.547Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formula:C17H16N6O3SColore e forma:SolidPeso molecolare:384.41Tyrosinase-IN-26
Tyrosinase-IN-26 (compound 13) is a non-competitive inhibitor of tyrosinase, with an IC50 value of 68.86 µM. It is capable of inhibiting melanin production.Formula:C25H24N2O6Peso molecolare:448.16344Tyrosinase
CAS:<p>Tyrosinase (Polyphenol oxidase) is a key rate-limiting enzyme encoded by the TYR gene that controls melanin production and catalyzes tyrosine oxidation.</p>Colore e forma:Solid5,6-Dihydro-2H-pyran-2-one
CAS:5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Formula:C5H6O2Colore e forma:SolidPeso molecolare:98.1CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Formula:C23H21N5O3SColore e forma:SolidPeso molecolare:447.51VM4-037
CAS:VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Formula:C26H29FN6O7S2Colore e forma:SolidPeso molecolare:620.67CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Formula:C19H16ClN3O5S2Colore e forma:SolidPeso molecolare:465.93CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Colore e forma:Odour SolidTyrosinase-IN-40
Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.Formula:C34H29N9O10Colore e forma:SolidPeso molecolare:723.648Peroxidase
CAS:Purezza:≥ 85units/mg (dry basis)Colore e forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecolare:-[Asp371]-Tyrosinase (369-377), human
CAS:Tyrosinase (369-377,YMDGTMSQV) originates from tyrosinase and needs TAP and proteosome for cell presentation.Formula:C42H66N10O16S2Purezza:98%Colore e forma:SolidPeso molecolare:1031.16hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Colore e forma:Odour SolidCAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Colore e forma:Odour SolidhCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formula:C23H22N4O7S2Colore e forma:SolidPeso molecolare:530.573Carbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Colore e forma:Odour SolidChlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formula:C7H6ClN3O4S2Purezza:98.46% - 98.91%Colore e forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecolare:295.72CAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Formula:C16H13FNO4PColore e forma:SolidPeso molecolare:333.05662Chlorzolamide
CAS:CHLORZOLAMIDE is a sulfonamide-based inhibitor that exhibits cytotoxic effects on prostate cancer cells.Formula:C8H6ClN3O2S2Peso molecolare:275.74IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Formula:C19H17N3O5Purezza:98.77% - 99.91%Colore e forma:SoildPeso molecolare:367.36hCAIX/XII-IN-10
hCAIX/XII-IN-10 (compound DK-8) is an inhibitor of Carbonic Anhydrase, showing potent inhibitory activity against the tumor-associated membrane-bound isoforms hCA IX and XII, with Ki values of 32.5 nM and 29.2 nM, respectively.Formula:C17H13N3O5SPeso molecolare:371.05759Pyrocatechol
CAS:Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Formula:C6H6O2Purezza:99.96%Colore e forma:SolidPeso molecolare:110.11DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formula:C17H20N2O5SColore e forma:SolidPeso molecolare:364.42Trypsin, bovine origin
CAS:Purezza:≥ 2000units/mg (USP)Colore e forma:White or almost white crystalline powderPeso molecolare:-Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formula:C6H8N2O2SColore e forma:SolidPeso molecolare:172.2Pseudostellarin G
CAS:Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Formula:C42H56N8O9Colore e forma:SolidPeso molecolare:816.94Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formula:C26H28N4O6S2Peso molecolare:556.14503TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingColore e forma:Odour SolidAc-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormula:C47H64N14O10Colore e forma:SolidPeso molecolare:985.1Peroxidase, from horseradish, approx. 200 U/mg
CAS:Purezza:≥ 150U/mgColore e forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecolare:-Proteinase K
CAS:Purezza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Colore e forma:White or almost white lyophilized powderPeso molecolare:-Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formula:C15H19NO3Colore e forma:SolidPeso molecolare:261.32P-Hydroxybenzoate Hydroxylase
CAS:Colore e forma:Yellowish lyophilised powderPeso molecolare:55 ~ 60 kDaLysozyme, from chicken egg white
CAS:Purezza:≥ 20,000U/mgColore e forma:White to off-white powderPeso molecolare:-Butobendine
CAS:Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Formula:C32H48N2O10Peso molecolare:620.73Anhydrotetracycline hydrochloride
CAS:Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.Formula:C22H23ClN2O7Purezza:98% - 98.90%Colore e forma:SolidPeso molecolare:462.88Calmodulin-dependent Protein Kinase II fragment 290-309
CAS:Formula:C103H185N31O24SPeso molecolare:2273.83Xanthine Oxidase, ammonium sulfate suspension
CAS:Colore e forma:Faint brown to dark brown suspensionhCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Formula:C15H16N2O5SPurezza:99.73%Colore e forma:SoildPeso molecolare:336.36β-Amylase, from soy
CAS:Purezza:≥ 10.0units/mgColore e forma:White to off-white powderPeso molecolare:-2,3-Dihydroisoginkgetin
CAS:2,3-Dihydroisoginkgetin is a Tyrosinase inhibitor with 36.84% inhibition at 0.1 mM.Formula:C32H24O10Purezza:98%Colore e forma:SolidPeso molecolare:568.53Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Colore e forma:Odour SolidTrkA Protein, Rat, Recombinant (hFc)
TrkA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Colore e forma:Lyophilized PowderPeso molecolare:69.2 kDa (predicted); 92-102 kDa (reducing conditions)TrkB Protein, Canine, Recombinant (hFc)
<p>TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Colore e forma:Lyophilized PowderPeso molecolare:71.2 kDa (predicted)TrkA Protein, Rabbit, Recombinant (His)
TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Colore e forma:Lyophilized PowderPeso molecolare:43.4 kDa (predicted)TrkB Protein, Human, Recombinant (His) V2
Expression System: HEK293 Cells<br>Length: 32-430, Extracellular Domain<br>Activity: ELISAPeso molecolare:45.2 kDa (Predicted); 65-80 kDa (Due to glycosylation)TrkA Protein, Human, Recombinant (His)
<p>TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Purezza:98.7%Colore e forma:Lyophilized PowderPeso molecolare:39.5 kDa (predicted); 60-65 kDa (reducing condition, due to glycosylation)Cuprizone
CAS:Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.Formula:C14H22N4O2Purezza:≥98%Colore e forma:SolidPeso molecolare:278.35p38 γ/MAPK12 Protein, Human, Recombinant
p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells.Colore e forma:Lyophilized PowderPeso molecolare:42.1 kDa (predicted); 43 kDa (reducing conditions)TrkB Protein, Human, Recombinant (His)
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purezza:99.3%Colore e forma:Lyophilized PowderPeso molecolare:45.7 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Thrombopoietin Protein, Mouse, Recombinant (C-His)
Expression System: HEK293 Cells<br>Length: 22-356, Full Length of Mature Protein<br>Activity: Cell ActivityPeso molecolare:37.20 kDa (Predicted); 75-95 kDa (Due to glycosylation)ErbB4 Protein, Rat, Recombinant (His)
ErbB4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Colore e forma:Lyophilized PowderPeso molecolare:71.3 kDa (predicted); 75-95 kDa (reducing condition, due to glycosylation)
![[Asp371]-Tyrosinase (369-377), human](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1623.webp&w=3840&q=75)
![Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76347.webp&w=3840&q=75)
