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NF-κB

NF-κB

Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.

Trovati 444 prodotti di "NF-κB"

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  • TH023


    <p>TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.</p>
    Formula:C22H21ClF2N4O
    Colore e forma:Solid
    Peso molecolare:430.88
  • NF-κΒ activator 1

    CAS:
    NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
    Formula:C16H11FN2O2S
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:314.33
  • Antidesmone

    CAS:
    Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.
    Formula:C19H29NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:319.44
  • PROTAC STING degrader-3


    PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.
    Colore e forma:Odour Solid
  • Lemnalol

    CAS:
    <p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>
    Formula:C15H24O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:220.35
  • Cyclo(L-Pro-L-Val)

    CAS:
    <p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>
    Formula:C10H16N2O2
    Purezza:98.18%
    Colore e forma:Solid
    Peso molecolare:196.25
  • Anti-inflammatory agent 51

    CAS:
    Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury and ulcerative colitis.
    Formula:C22H22N6O6S
    Purezza:99.76%
    Colore e forma:Soild
    Peso molecolare:498.51
  • EN450

    CAS:
    EN450 is a targeted cysteine degrader of NF-κB with antiproliferative activity and potential anticancer activity for the study of leukemia.
    Formula:C11H13ClN2O3S
    Purezza:98.39%
    Colore e forma:Soild
    Peso molecolare:288.75
  • HS-243

    CAS:
    <p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>
    Formula:C17H16N4O3
    Purezza:98.62%
    Colore e forma:Solid
    Peso molecolare:324.33
  • COX-2-IN-48


    COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.
    Colore e forma:Odour Solid
  • Transcription Factor-Targeted Compound Library


    Well-chosen xnum compounds with unique structures targeting transcription factor;
    Colore e forma:Odour Solid
  • CAY10512

    CAS:
    CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.
    Formula:C15H13FO
    Colore e forma:Solid
    Peso molecolare:228.266
  • IKKγ NBD Inhibitory Peptide

    CAS:
    <p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>
    Formula:C170H259N49O42S1
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3693.3
  • PROTAC IRAK4 degrader-12

    CAS:
    PROTAC IRAK4 degrader-12, a Cereblon ligand-based PROTAC, induces a maximum degradation of IRAK4 in K562 cells at 108.46% with an IC50 value of 4.87 nM. (Structure Note: Pink, IRAK4 Inhibitor; Blue, E3; Black, linker.)
    Formula:C46H50ClF2N11O6
    Colore e forma:Solid
    Peso molecolare:926.41
  • (R)-(-)-Ibuprofen

    CAS:
    (R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.
    Formula:C13H18O2
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:206.28
  • Coronalolic acid

    CAS:
    Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced NF-κB activity and NO production.
    Formula:C30H46O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:470.68
  • MJ210


    <p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>
    Colore e forma:Odour Solid
  • NF-κB Signaling Compound Library


    A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;
    Colore e forma:Odour Solid
  • PROTAC IRAK4 ligand-4

    CAS:
    PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.
    Formula:C24H26F2N6O3
    Colore e forma:Solid
    Peso molecolare:484.5
  • Mitogen-activated protein kinase 1

    CAS:
    Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases.
    Purezza:98%
    Colore e forma:Solid
  • SEMBL

    CAS:
    SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.
    Formula:C12H11NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:233.22
  • RS 09

    CAS:
    TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
    Formula:C31H49N9O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:691.78
  • IRAK4-IN-8

    CAS:
    <p>IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and inflammation.</p>
    Formula:C23H23F2N7O2S
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:499.54
  • IRAK4-IN-10

    CAS:
    IRAK4-IN-10, a potent IRAK4 blocker with IC50 of 1.5 nM, may treat inflammation, autoimmunity, and cancer.
    Formula:C22H24N8
    Purezza:98.55%
    Colore e forma:Solid
    Peso molecolare:400.48
  • DTP3

    CAS:
    DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
    Formula:C26H35N7O5
    Colore e forma:Solid
    Peso molecolare:525.6
  • IRAK inhibitor 2

    CAS:
    IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.
    Formula:C17H14N4O2
    Purezza:97.90% - 99.58%
    Colore e forma:Solid
    Peso molecolare:306.32
  • ML 120B dihydrochloride

    CAS:
    MLN120B dihydrochloride: oral IKKβ inhibitor with 60 nM IC50, suppresses myeloma growth, used in arthritis research.
    Formula:C19H17Cl3N4O2
    Colore e forma:Solid
    Peso molecolare:439.72
  • Hesperidin methylchalcone

    CAS:
    Hesperidin methylchalcone, from Citrus, is a potent antioxidant that inhibits NF-κB to alleviate gout arthritis in mice.
    Formula:C29H36O15
    Purezza:99.53%
    Colore e forma:Yellow Powder
    Peso molecolare:624.59
  • BIZ 114

    CAS:
    BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.
    Formula:C24H40O3
    Colore e forma:Solid
    Peso molecolare:376.57
  • Edecesertib

    CAS:
    Edecesertib (GS 5718) is an IRAK-4 inhibitor with anti-inflammatory activity for the study of rheumatoid arthritis.
    Formula:C22H22FN7O2
    Purezza:98.84% - 99.94%
    Colore e forma:Solid
    Peso molecolare:435.45
  • Stachydrine

    CAS:
    <p>Stachydrine, found in leonurus herb, aids blood flow, blocks NF-κB pathway, and indicates citrus intake.</p>
    Formula:C7H13NO2
    Purezza:99.94% - ≥95%
    Colore e forma:Solid
    Peso molecolare:143.18
  • BMS-345541

    CAS:
    BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
    Formula:C14H17N5
    Purezza:99.36% - 99.74%
    Colore e forma:Solid
    Peso molecolare:255.32
  • Bay 11-7085

    CAS:
    Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
    Formula:C13H15NO2S
    Purezza:99.76% - 99.94%
    Colore e forma:White Solid
    Peso molecolare:249.33
  • 1-Caffeoylquinic acid

    CAS:
    1-Caffeoylquinic acid: a lignin precursor with anti-influenza, antioxidant properties, and moderates post-meal glucose release.
    Formula:C16H18O9
    Purezza:99.15% - 99.16%
    Colore e forma:Solid
    Peso molecolare:354.31
  • Pyrrolidinedithiocarbamate ammonium

    CAS:
    Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide
    Formula:C5H12N2S2
    Purezza:98% - >99.99%
    Colore e forma:Off-White To Pale Yellow Crystals
    Peso molecolare:164.29
  • QNZ

    CAS:
    QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.
    Formula:C22H20N4O
    Purezza:99.17% - 99.18%
    Colore e forma:White Solid
    Peso molecolare:356.42
  • TOMATIDINE HYDROCHLORIDE

    CAS:
    Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.
    Formula:C27H46ClNO2
    Purezza:99.75% - ≥95%
    Colore e forma:Solid
    Peso molecolare:452.11
  • BEC hydrochloride

    CAS:
    BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.
    Formula:C5H12BNO4S·ClH
    Purezza:98.65% - 99.28%
    Colore e forma:Solid
    Peso molecolare:229.49
  • Quinoclamine

    CAS:
    Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.
    Formula:C10H6ClNO2
    Purezza:99.13% - 99.28%
    Colore e forma:Orange Powder
    Peso molecolare:207.61
  • CAFESTOL

    CAS:
    <p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>
    Formula:C20H28O3
    Purezza:97.06% - 99.08%
    Colore e forma:Solid
    Peso molecolare:316.43
  • IMM-H007

    CAS:
    IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
    Formula:C22H23N5O8
    Purezza:97.73%
    Colore e forma:Solid
    Peso molecolare:485.45
  • Morusin

    CAS:
    Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.
    Formula:C25H24O6
    Purezza:98.68% - 99.8%
    Colore e forma:Solid
    Peso molecolare:420.45
  • EUK-134

    CAS:
    EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
    Formula:C18H18ClMnN2O4
    Purezza:98.39%
    Colore e forma:Solid
    Peso molecolare:416.74
  • Ethacrynic acid

    CAS:
    Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。
    Formula:C13H12Cl2O4
    Purezza:98.61% - 99.85%
    Colore e forma:Crystals Physical Description White Solid (Ntp 1992)
    Peso molecolare:303.14
  • 3'-Sialyllactose

    CAS:
    3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.
    Formula:C23H39NO19
    Colore e forma:Solid
    Peso molecolare:633.55
  • Flavanomarein

    CAS:
    Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.
    Formula:C21H22O11
    Purezza:98.63% - 99.54%
    Colore e forma:Solid
    Peso molecolare:450.39
  • Sulfuretin

    CAS:
    <p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>
    Formula:C15H10O5
    Purezza:98.91% - 99.86%
    Colore e forma:Solid
    Peso molecolare:270.24
  • OPHIOPOGONIN D

    CAS:
    Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
    Formula:C44H70O16
    Purezza:99.46% - ≥95%
    Colore e forma:Solid
    Peso molecolare:855.02
  • Demethyleneberberine

    CAS:
    Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either
    Formula:C19H18NO4
    Purezza:98.08% - 99.18%
    Colore e forma:Solid
    Peso molecolare:324.35
  • Bortezomib

    CAS:
    Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.
    Formula:C19H25BN4O4
    Purezza:97.79% - >99.99%
    Colore e forma:Yellow Solid
    Peso molecolare:384.24
  • (E/Z)-IT-603

    CAS:
    (E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.
    Formula:C11H9BrN2O3S
    Purezza:99.35%
    Colore e forma:Solid
    Peso molecolare:329.17
  • Benzoyloxypaeoniflorin

    CAS:
    Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.
    Formula:C30H32O13
    Purezza:98.52% - 99.96%
    Colore e forma:Solid
    Peso molecolare:600.57
  • Astaxanthin

    CAS:
    <p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>
    Formula:C40H52O4
    Purezza:95.1% - 99.79%
    Colore e forma:Needles From Acetone/Light Petroleum Solid
    Peso molecolare:596.84
  • Rocaglamide

    CAS:
    Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.
    Formula:C29H31NO7
    Purezza:95.32% - 99.67%
    Colore e forma:Solid
    Peso molecolare:505.56
  • Flaconitine

    CAS:
    <p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>
    Formula:C36H49NO12
    Purezza:98% - 99.84%
    Colore e forma:Solid
    Peso molecolare:687.77
  • Vanillic Acid

    CAS:
    Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.
    Formula:C8H8O4
    Purezza:99.82%
    Colore e forma:White Odourless Crystals Or Powder
    Peso molecolare:168.15
  • 18α-Glycyrrhetinic acid

    CAS:
    18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.
    Formula:C30H46O4
    Purezza:98.54% - 99.68%
    Colore e forma:Solid
    Peso molecolare:470.68
  • Rhoifolin

    CAS:
    Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
    Formula:C27H30O14
    Purezza:98.11% - 98.58%
    Colore e forma:Solid
    Peso molecolare:578.52
  • BOT-64

    CAS:
    BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole
    Formula:C15H15NO2S
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:273.35
  • 2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC

    CAS:
    <p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>
    Formula:C11H10N2OS
    Purezza:99.48%
    Colore e forma:Solid
    Peso molecolare:218.27
  • Licochalcone D

    CAS:
    Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.
    Formula:C21H22O5
    Purezza:99.03% - 99.9%
    Colore e forma:Solid
    Peso molecolare:354.4
  • Micheliolide

    CAS:
    Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.
    Formula:C15H20O3
    Purezza:98% - 99.37%
    Colore e forma:Solid
    Peso molecolare:248.32
  • Galloylpaeoniflorin

    CAS:
    Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.
    Formula:C30H32O15
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:632.57
  • Asperulosidic acid

    CAS:
    Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.
    Formula:C18H24O12
    Purezza:99.47%
    Colore e forma:Solid
    Peso molecolare:432.38
  • Rubiadin-1-methyl ether

    CAS:
    <p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>
    Formula:C16H12O4
    Purezza:98.32%
    Colore e forma:Solid
    Peso molecolare:268.26
  • Curculigoside

    CAS:
    1.
    Formula:C22H26O11
    Purezza:99.85%
    Colore e forma:Solid
    Peso molecolare:466.44
  • Rucaparib

    CAS:
    Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.
    Formula:C19H18FN3O
    Purezza:98.24% - 99.80%
    Colore e forma:Solid
    Peso molecolare:323.36
  • Neochlorogenic acid

    CAS:
    Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
    Formula:C16H18O9
    Purezza:99.12% - 99.54%
    Colore e forma:White Powder
    Peso molecolare:354.31
  • AS-2444697

    CAS:
    AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.
    Formula:C19H21ClN6O4
    Purezza:97.17%
    Colore e forma:Solid
    Peso molecolare:432.86
  • Chelidonic acid

    CAS:
    Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.
    Formula:C7H4O6
    Purezza:99.03%
    Colore e forma:Solid
    Peso molecolare:184.10
  • IRAK4-IN-7

    CAS:
    IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.
    Formula:C21H19N7O3
    Purezza:99.5%
    Colore e forma:Solid
    Peso molecolare:417.42
  • Cyclo(his-pro)

    CAS:
    <p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>
    Formula:C11H14N4O2
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:234.25
  • Ac2-26 acetate


    Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).
    Formula:C141H210N32O44S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3089.43
  • Dehydroevodiamine

    CAS:
    Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant
    Formula:C19H15N3O
    Purezza:99.54%
    Colore e forma:Solid
    Peso molecolare:301.34
  • Berbamine

    CAS:
    Berbamine is a natural product extracted from Phellodendron amurense.
    Formula:C37H40N2O6
    Purezza:98.92% - 99.67%
    Colore e forma:White Crystal Powder
    Peso molecolare:608.72
  • Tizoxanide

    CAS:
    Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.
    Formula:C10H7N3O4S
    Purezza:98.89% - 99.28%
    Colore e forma:Solid
    Peso molecolare:265.25
  • GSK8612

    CAS:
    GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .
    Formula:C17H17BrF3N7O2S
    Purezza:99.68% - 99.99%
    Colore e forma:Solid
    Peso molecolare:520.33
  • MLN120B

    CAS:
    MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
    Formula:C19H15ClN4O2
    Purezza:98.92%
    Colore e forma:Solid
    Peso molecolare:366.8
  • Avicularin

    CAS:
    Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.
    Formula:C20H18O11
    Purezza:97.02% - 99.94%
    Colore e forma:White Powder
    Peso molecolare:434.35
  • Convallatoxin

    CAS:
    Convallatoxin is a natural product.
    Formula:C29H42O10
    Purezza:99.27% - 99.53%
    Colore e forma:Prisms From Methanol + Ether Solid
    Peso molecolare:550.64
  • Dauricine

    CAS:
    1.
    Formula:C38H44N2O6
    Purezza:99.24% - 99.75%
    Colore e forma:White Powder
    Peso molecolare:624.77
  • Dendrophenol

    CAS:
    Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.
    Formula:C17H20O5
    Purezza:98.2% - 99.36%
    Colore e forma:Solid
    Peso molecolare:304.34
  • Ginsenoside Rb3

    CAS:
    Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.
    Formula:C53H90O22
    Purezza:98% - 99.98%
    Colore e forma:Solid
    Peso molecolare:1079.27
  • Ginsenoside Rk3

    CAS:
    Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.
    Formula:C36H60O8
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:620.86
  • SC-514

    CAS:
    <p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>
    Formula:C9H8N2OS2
    Purezza:99.88% - >99.99%
    Colore e forma:Solid
    Peso molecolare:224.3
  • yangonin

    CAS:
    Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.
    Formula:C15H14O4
    Purezza:98.82% - 99.55%
    Colore e forma:Pale Yellow Powder
    Peso molecolare:258.27
  • Iron sucrose

    CAS:
    <p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>
    Formula:C18H24Fe2O24
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:736.1
  • Sinomenine

    CAS:
    <p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>
    Formula:C19H23NO4
    Purezza:99.02% - 99.73%
    Colore e forma:White Powder
    Peso molecolare:329.39
  • ISOGINKGETIN

    CAS:
    <p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>
    Formula:C32H22O10
    Purezza:98% - 99.72%
    Colore e forma:Solid
    Peso molecolare:566.51
  • Triacetylresveratrol

    CAS:
    <p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>
    Formula:C20H18O6
    Purezza:99.81%
    Colore e forma:Off White Powder
    Peso molecolare:354.35
  • Muscone

    CAS:
    <p>Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.</p>
    Formula:C16H30O
    Purezza:98.97% - ≥98%
    Colore e forma:Colourless Liquid Liquid
    Peso molecolare:238.41
  • Isoquercetin

    CAS:
    1.
    Formula:C21H20O12
    Purezza:98.08% - 99.76%
    Colore e forma:Solid
    Peso molecolare:464.38
  • Ginsenoside Rb1

    CAS:
    Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
    Formula:C54H92O23
    Purezza:99.12% - 99.76%
    Colore e forma:Solid
    Peso molecolare:1109.29
  • Ginsenoside Rd

    CAS:
    <p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purezza:99.13% - 99.92%
    Colore e forma:Solid
    Peso molecolare:947.15
  • Eclitasertib

    CAS:
    <p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of &lt;1 µΜ).</p>
    Formula:C19H18N6O3
    Purezza:99.85%
    Colore e forma:Solid
    Peso molecolare:378.38
  • Cornuside

    CAS:
    Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.
    Formula:C24H30O14
    Purezza:99.86% - >99.99%
    Colore e forma:Solid
    Peso molecolare:542.49
  • 2-Hydroxychalcone

    CAS:
    2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.
    Formula:C15H12O2
    Purezza:99.6%
    Colore e forma:Solid
    Peso molecolare:224.25
  • Nitidine chloride

    CAS:
    1.
    Formula:C21H18ClNO4
    Purezza:96.59% - 99.55%
    Colore e forma:Solid
    Peso molecolare:383.82
  • WITHAFERIN A

    CAS:
    WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/
    Formula:C28H38O6
    Purezza:97.41% - 99.99%
    Colore e forma:Solid
    Peso molecolare:470.60
  • 2,5-Dihydroxyacetophenone

    CAS:
    2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.
    Formula:C8H8O3
    Purezza:99.75%
    Colore e forma:Yellow Powder
    Peso molecolare:152.15