NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 443 prodotti di "NF-κB"
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Berbamine
CAS:<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formula:C37H40N2O6Purezza:98.92% - 99.67%Colore e forma:White Crystal PowderPeso molecolare:608.72Dauricine
CAS:<p>1.</p>Formula:C38H44N2O6Purezza:99.24% - 99.75%Colore e forma:White PowderPeso molecolare:624.77Dendrophenol
CAS:<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Formula:C17H20O5Purezza:98.2% - 99.36%Colore e forma:SolidPeso molecolare:304.34SC-514
CAS:<p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>Formula:C9H8N2OS2Purezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:224.3yangonin
CAS:<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formula:C15H14O4Purezza:98.82% - 99.55%Colore e forma:Pale Yellow PowderPeso molecolare:258.27Iron sucrose
CAS:<p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>Formula:C18H24Fe2O24Purezza:99.97%Colore e forma:SolidPeso molecolare:736.1Neochlorogenic acid
CAS:<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formula:C16H18O9Purezza:99.12% - 99.54%Colore e forma:White PowderPeso molecolare:354.31Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formula:C20H18O6Purezza:99.81%Colore e forma:Off White PowderPeso molecolare:354.35Micheliolide
CAS:<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formula:C15H20O3Purezza:98% - 99.37%Colore e forma:SolidPeso molecolare:248.32Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Formula:C21H22O5Purezza:99.03% - 99.9%Colore e forma:SolidPeso molecolare:354.4Nitidine chloride
CAS:1.Formula:C21H18ClNO4Purezza:96.59% - 99.55%Colore e forma:SolidPeso molecolare:383.82Rhoifolin
CAS:<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formula:C27H30O14Purezza:98.11% - 98.58%Colore e forma:SolidPeso molecolare:578.52Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Formula:C54H92O23Purezza:99.12% - 99.76%Colore e forma:SolidPeso molecolare:1109.29GSK481
CAS:<p>GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.</p>Formula:C21H19N3O4Purezza:98.97%Colore e forma:SolidPeso molecolare:377.39Convallatoxin
CAS:<p>Convallatoxin is a natural product.</p>Formula:C29H42O10Purezza:99.27% - 99.53%Colore e forma:Prisms From Methanol + Ether SolidPeso molecolare:550.64Cornuside
CAS:<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Formula:C24H30O14Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:542.49Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formula:C19H25BN4O4Purezza:97.79% - >99.99%Colore e forma:Yellow SolidPeso molecolare:384.24Benzoyloxypaeoniflorin
CAS:<p>Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.</p>Formula:C30H32O13Purezza:98.52% - 99.96%Colore e forma:SolidPeso molecolare:600.57Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFormula:C5H12N2S2Purezza:98% - >99.99%Colore e forma:Off-White To Pale Yellow CrystalsPeso molecolare:164.29Sodium Aescinate
CAS:<p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>Formula:C54H83NaO23Purezza:95.17%Colore e forma:SolidPeso molecolare:1123.21Specnuezhenide
CAS:<p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>Formula:C31H42O17Purezza:98% - 99.93%Colore e forma:SolidPeso molecolare:686.66γ-Tocotrienol
CAS:<p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>Formula:C28H42O2Purezza:97.27% - 98.13%Colore e forma:SolidPeso molecolare:410.63Ginsenoside Rk3
CAS:Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.Formula:C36H60O8Purezza:99.88%Colore e forma:SolidPeso molecolare:620.86MLN120B
CAS:<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Formula:C19H15ClN4O2Purezza:98.92%Colore e forma:SolidPeso molecolare:366.8PTP1B-IN-1
CAS:PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)Formula:C8H8N2O3SPurezza:99.27%Colore e forma:SolidPeso molecolare:212.23MD2-TLR4-IN-1
CAS:<p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>Formula:C22H14Cl2N4OPurezza:97.74%Colore e forma:SolidPeso molecolare:421.28Rubiadin-1-methyl ether
CAS:<p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>Formula:C16H12O4Purezza:98.32%Colore e forma:SolidPeso molecolare:268.26Rhynchophylline
CAS:Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.Formula:C22H28N2O4Purezza:99.44% - 99.98%Colore e forma:Red Brown Or White Fine PowderPeso molecolare:384.47ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formula:C11H12O4Purezza:97.79%Colore e forma:SolidPeso molecolare:208.21GSK583
CAS:<p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>Formula:C20H19FN4O2SPurezza:98.68% - 99.81%Colore e forma:SolidPeso molecolare:398.45Isovitexin
CAS:<p>1.</p>Formula:C21H20O10Purezza:99.79% - 99.97%Colore e forma:SolidPeso molecolare:432.38Denosumab
CAS:<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formula:C6404H9912N1724O2004S50Purezza:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Colore e forma:LiquidPeso molecolare:144.71 kDaJTP 0819958 - HOIPIN-1
<p>JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.</p>Formula:C17H13NaO4Purezza:99.95%Colore e forma:SolidPeso molecolare:304.27Diethylmaleate
CAS:<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formula:C8H12O4Purezza:98%Colore e forma:Colourless LiquidPeso molecolare:172.18Chelidonic acid
CAS:<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formula:C7H4O6Purezza:99.03%Colore e forma:SolidPeso molecolare:184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formula:C141H210N32O44SPurezza:98%Colore e forma:SolidPeso molecolare:3089.43Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purezza:99.02% - 99.73%Colore e forma:White PowderPeso molecolare:329.39ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purezza:98% - 99.72%Colore e forma:SolidPeso molecolare:566.51AZD3264
CAS:<p>AZD3264 is a new type IKK2 inhibitor.</p>Formula:C21H23N5O4SPurezza:98.98% - 99.17%Colore e forma:SolidPeso molecolare:441.5Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purezza:95.1% - 99.79%Colore e forma:Needles From Acetone/Light Petroleum SolidPeso molecolare:596.84Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purezza:95.32% - 99.67%Colore e forma:SolidPeso molecolare:505.56Ethacrynic acid
CAS:<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formula:C13H12Cl2O4Purezza:98.61% - 99.85%Colore e forma:Crystals Physical Description White Solid (Ntp 1992)Peso molecolare:303.14Quinoclamine
CAS:<p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>Formula:C10H6ClNO2Purezza:99.13% - 99.28%Colore e forma:Orange PowderPeso molecolare:207.617,4'-Dihydroxyflavone
CAS:<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formula:C15H10O4Purezza:99.39% - 99.6%Colore e forma:SolidPeso molecolare:254.24Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formula:C19H18FN3OPurezza:98.24% - 99.80%Colore e forma:SolidPeso molecolare:323.36Geranylgeraniol
CAS:<p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>Formula:C20H34OPurezza:99.17% - ≥98%Colore e forma:SolidPeso molecolare:290.48Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purezza:99.35% - 99.73%Colore e forma:SolidPeso molecolare:274.36GSK2982772
CAS:<p>GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.</p>Formula:C20H19N5O3Purezza:99.27% - 99.31%Colore e forma:SolidPeso molecolare:377.4IRAK inhibitor 1
CAS:<p>IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).</p>Formula:C17H19N5Purezza:97.5% - 99.89%Colore e forma:SolidPeso molecolare:293.37
