CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 142 prodotti di "CCR"
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J-113863
CAS:J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM).Formula:C30H37Cl2IN2O2Purezza:95.11%Colore e forma:SolidPeso molecolare:655.44Ref: TM-T11699
1mg59,00€2mg87,00€5mg126,00€10mg169,00€25mg304,00€50mg527,00€100mg758,00€1mL*10mM (DMSO)180,00€CCR2-RA-[R]
CAS:CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).Formula:C18H19ClFNO3Purezza:99.7%Colore e forma:SolidPeso molecolare:351.8RS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formula:C21H22ClF3N2O2Purezza:98.95%Colore e forma:SolidPeso molecolare:426.86Leronlimab
CAS:Leronlimab (PRO 140), a humanized IgG4 monoclonal antibody, targets CCR5 to combat HIV and cancer.Purezza:SDS-PAGE:95.0%;SEC-HPLC:99.6%Colore e forma:LiquidPeso molecolare:146.66 kDaMogamulizumab
CAS:<p>Mogamulizumab is a monoclonal antibody targeting CC chemokine receptor 4 with anticancer effects, used in ATLL and CTCL studies.</p>Purezza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Colore e forma:LiquidPeso molecolare:146.43 kDaML604086
CAS:ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations.Formula:C27H32N4O4SPurezza:99.91%Colore e forma:SolidPeso molecolare:508.63INCB-9471
CAS:INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.Formula:C30H40F3N5O2Purezza:98.80%Colore e forma:SolidPeso molecolare:559.666MK-0812 Succinate
CAS:MK-0812 Succinate is an effective and selective CCR2 antagonist.Formula:C28H40F3N3O7Purezza:98.62% - 99.93%Colore e forma:SolidPeso molecolare:587.63CCX140
CAS:CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.Formula:C20H13ClF3N5O3SPurezza:99.66% - 99.95%Colore e forma:SolidPeso molecolare:495.86AZ084
CAS:AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.Formula:C26H34N4O2Purezza:97.12%Colore e forma:SolidPeso molecolare:434.57Ref: TM-T10425
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)182,00€CKLF1-C27 TFA
CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.Formula:C153H244F3N39O39Colore e forma:SolidPeso molecolare:3310.8BMS-753426
CAS:<p>BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .</p>Formula:C25H33F3N6O2Colore e forma:SolidPeso molecolare:506.574SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Formula:C22H26N4O5Colore e forma:SolidPeso molecolare:426.47PF-232798
CAS:PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.Formula:C29H40FN5O2Colore e forma:SolidPeso molecolare:509.66INCB 3284 dimesylate
CAS:INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Formula:C28H39F3N4O10S2Purezza:98%Colore e forma:SolidPeso molecolare:712.76MLN-3897 TFA
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.Formula:C32H32ClF3N2O6Purezza:98.62%Colore e forma:SolidPeso molecolare:633.05Ref: TM-T28072L
1mg115,00€5mg245,00€10mg363,00€25mg562,00€50mg775,00€100mg1.035,00€200mg1.406,00€1mL*10mM (DMSO)Prezzo su richiestaZn-DPA-maytansinoid conjugate 1
Zn-DPA-maytansinoid 1 targets checkpoints, shrinks tumors, and heats TME.Formula:C115H145ClN18O31S2Zn2Colore e forma:SolidPeso molecolare:2505.83Bertilimumab
CAS:<p>Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].</p>Colore e forma:LiquidMet-RANTES,human,acetate
Met-RANTES (human) acetate is the acetate salt form of Met-RANTES (human). It acts as an antagonist for CCR1 and CCR5 receptors. This compound inhibits the human chemokines MIP-1α and MIP-1β, with respective IC50 values of 5 and 2 nM. Additionally, Met-RANTES (human) acetate reduces bone destruction and alleviates adjuvant-induced arthritis (AIA) in rats.Colore e forma:Odour SolidCCR4 antagonist 3
CAS:Orally active CCR4 antagonist with piperidinyl-azetidine; IC50: 22 nM (calcium flux), 50 nM (CTX); antitumor effects.Formula:C24H27Cl2N7OColore e forma:SolidPeso molecolare:500.43
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