MEK
MEK è una chinasi a doppia specificità che svolge un ruolo centrale nella via di segnalazione MAPK/ERK attivando ERK attraverso la fosforilazione. La segnalazione MEK è cruciale per la regolazione della crescita, sopravvivenza e differenziazione cellulare. Un'attività anomala di MEK è stata implicata in vari tipi di cancro e disturbi dello sviluppo, rendendola un importante bersaglio terapeutico. Presso CymitQuimica, offriamo una varietà di inibitori e modulatori di MEK per supportare la tua ricerca in oncologia, segnalazione cellulare e sviluppo terapeutico.
Trovati 75 prodotti per "MEK".
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PD 198306
CAS:PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.Formula:C18H16F3IN2O2Purezza:99.66%Colore e forma:SolidPeso molecolare:476.23Ref: TM-T21980
1mg60,00€5mg131,00€1mL*10mM (DMSO)152,00€10mg178,00€25mg314,00€50mg447,00€100mg622,00€500mg1.224,00€Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurezza:99.88% - >99.99%Colore e forma:White SolidPeso molecolare:234.34Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurezza:99.95%Colore e forma:SolidPeso molecolare:288.82Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formula:C14H23ClN2OPurezza:99.83% - 99.92%Colore e forma:SolidPeso molecolare:270.798Cobimetinib (R-enantiomer)
CAS:Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.Formula:C21H21F3IN3O2Purezza:98%Colore e forma:SolidPeso molecolare:531.318MAPK Inhibitor Library
A unique collection of xnum cancer cell differentiation inducing compounds for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L1400
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaLuvometinib-d
Luvometinib-d is a deuterium-labeled version of Luvometinib, which is a mitogen-activated protein kinase (MEK) inhibitor with antitumor properties.MEK1/2-IN-3
MEK1/2-IN-3 (Compound M15) is an inhibitor of MEK1, with an IC50 value of 10.29 nM. It effectively suppresses tumor cell proliferation and migration, induces apoptosis, and exhibits good liver microsomal stability. MEK1/2-IN-3 is applicable in the study of solid tumors.Formula:C28H23F3IN3O4Colore e forma:SolidPeso molecolare:649.4MEK4 inhibitor-1
CAS:MEK4 inhibitor-1 targets MEK4 enzyme in pancreatic cancer, IC50=61 nM.Formula:C13H10FN3O2SColore e forma:SolidPeso molecolare:291.3MS432
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.Formula:C50H65F3IN7O6SPurezza:98%Colore e forma:SolidPeso molecolare:1076.06U0124
CAS:Inactive analog of U0126(MEK-1/2 inhibitor), used as a negative controlFormula:C8H10N4S2Purezza:98%Colore e forma:SolidPeso molecolare:226.32FDA-Approved Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.Colore e forma:LiquidRef: TM-L1610
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaNST-628
CAS:NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK. NST-628 inhibits the RAF-MEK signaling complex.Formula:C22H18F2N4O5SPurezza:98.62% - 98.86%Colore e forma:White SolidPeso molecolare:488.46Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asColore e forma:Lyophilized PowderPeso molecolare:16.46 kDa (predicted) same as Tris-Bis PAGE result.Ref: TM-TMPK-00024
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€Midkine Protein, Human, Recombinant (His & Avi)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asPurezza:> 95% as determined by Bis-Tris PAGE - > 95% as determined by Bis-Tris PAGEColore e forma:White Lyophilized PowderPeso molecolare:16.46 kDa (predicted) same as Tris-Bis PAGE result.Anti-Midkine Antibody (5T766)
Anti-Midkine Antibody (5T766) is an antibody targeting Midkine. Anti-Midkine Antibody (5T766) can be used in ELISA, IHC.Colore e forma:Odour LiquidMidkine Protein, Mouse, Recombinant (His)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed asPurezza:> 95% as determined by Bis-Tris PAGE - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCColore e forma:Transparent SolutionPeso molecolare:14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.Refametinib
CAS:Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).Formula:C19H20F3IN2O5SPurezza:99.85% - >99.99%Colore e forma:SolidPeso molecolare:572.34Ref: TM-T6636
2mg43,00€5mg63,00€1mL*10mM (DMSO)79,00€10mg93,00€25mg147,00€50mg222,00€100mg326,00€200mg485,00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purezza:98.63% - >99.99%Colore e forma:Green SolidPeso molecolare:267.28Ref: TM-T2623
5mg38,00€1mL*10mM (DMSO)39,00€10mg50,00€25mg78,00€50mg101,00€100mg168,00€200mg250,00€500mg421,00€BIX02189
CAS:BIX 02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).Formula:C27H28N4O2Purezza:97.84%Colore e forma:SolidPeso molecolare:440.54Ref: TM-T21295
2mg33,00€5mg52,00€1mL*10mM (DMSO)55,00€10mg71,00€25mg119,00€50mg198,00€100mg296,00€200mg427,00€
