CFTR
CFTR è una proteina canale del cloruro che regola il trasporto di ioni cloruro e bicarbonato attraverso le membrane delle cellule epiteliali, svolgendo un ruolo cruciale nel mantenimento dell'equilibrio dei fluidi nei tessuti. Le mutazioni nel gene CFTR portano alla fibrosi cistica, un disturbo genetico caratterizzato dalla produzione di muco denso che può ostruire le vie respiratorie e causare gravi problemi respiratori e digestivi. Presso CymitQuimica, offriamo una selezione di modulatori CFTR per supportare la tua ricerca sulla fibrosi cistica, sul trasporto ionico e sui disturbi genetici.
Trovati 67 prodotti per "CFTR".
Filtra per
Percentuale di purezza
0
100
|
0
|
50
|
90
|
95
|
100
- Prezzo più basso
- Prezzo più alto
- Purezza più bassa
- Purezza più alta
- Consegna più veloce
Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurezza:99.05% - 99.75%Colore e forma:White SolidPeso molecolare:494.004Elexacaftor
CAS:Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Formula:C26H34F3N7O4SPurezza:98.87% - 99.87%Colore e forma:SolidPeso molecolare:597.653CFTR activator 2
CAS:CFTR activator 2 (WAY-326769) is an activator of mutant CFTR (cystic fibrosis transmembrane conductance regulator), which increases ion transport activity and can be used for research into cystic fibrosis (CF).Formula:C27H27N3O3Purezza:99.70%Colore e forma:SolidPeso molecolare:441.52H2-Gamendazole
CAS:H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Formula:C18H13Cl2F3N2O2Purezza:97.39%Colore e forma:SolidPeso molecolare:417.209Cavosonstat
CAS:Cavosonstat (N91115) is an oral GSNOR inhibitor aiding CFTR in cystic fibrosis.Formula:C16H10ClNO3Purezza:99.64%Colore e forma:Yellow SolidPeso molecolare:299.708Crofelemer
CAS:Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Colore e forma:SolidAstressin 2B
CAS:CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.Formula:C183H307N49O53Purezza:98%Colore e forma:SolidPeso molecolare:4041.69Urocortin III, mouse (free acid)
Urocortin III (mouse) is a CRF2 receptor agonist that slows gastric emptying without affecting colonic transit.Formula:C186H311N51S2Peso molecolare:4171.26Zatonacaftor
CAS:Zatonacaftor, a cystic fibrosis transmembrane regulator (CFTR) modulator, is utilized in the research of cystic fibrosis [1] [2].Formula:C24H27N3O4SColore e forma:SolidPeso molecolare:453.55(R)-Crinecerfont
CAS:4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomericFormula:C27H28ClFN2OSPurezza:98.51%Colore e forma:Orange SolidPeso molecolare:483.04kCAL01
CAS:kCAL01 is a CAL inhibitor with a Ki value of 2.3 μM and holds potential for research in cystic fibrosis (CF).Formula:C36H57N11O9Colore e forma:SolidPeso molecolare:787.91Vanzacaftor
CAS:Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.Formula:C32H39N7O4SPurezza:99.14%Colore e forma:White SolidPeso molecolare:617.76(Rac)-Tezacaftor
CAS:(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.Formula:C26H27F3N2O6Colore e forma:SolidPeso molecolare:520.5CP-628006
CAS:CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.Formula:C32H35F3N2O2Colore e forma:SolidPeso molecolare:536.639WAY-326766
CAS:WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formula:C21H23N3O5Purezza:99.87%Colore e forma:SolidPeso molecolare:397.4244Crinecerfont hydrochloride
CAS:SSR-125543, a potent CRF1 receptor non-peptide antagonist, effective in CAH research, taken orally.Formula:C27H29Cl2FN2OSColore e forma:SolidPeso molecolare:519.501Tezacaftor
CAS:Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formula:C26H27F3N2O6Purezza:98.84% - >99.99%Colore e forma:SolidPeso molecolare:520.4976KM11060
CAS:KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormula:C19H17Cl2N3O2SPurezza:99.08%Colore e forma:SolidPeso molecolare:422.328PPQ-102
CAS:PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).Formula:C26H22N4O3Purezza:98.80% - ≥95%Colore e forma:Yellow SolidPeso molecolare:438.4779IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formula:C22H15Br2N3O4Purezza:99% - >99.99%Colore e forma:SolidPeso molecolare:545.18
