Canale TRP/TRPV
canali TRP (Transient Receptor Potential), inclusa la sottofamiglia TRPV, sono un gruppo di canali ionici coinvolti in vari processi sensoriali, come la percezione della temperatura, la sensazione del dolore e l'osmoregolazione. I canali TRP sono ampiamente espressi in diversi tessuti e svolgono un ruolo nelle risposte fisiologiche agli stimoli ambientali. In particolare, i canali TRPV sono coinvolti nel rilevamento dei cambiamenti di temperatura e sono implicati in condizioni come il dolore cronico, l'infiammazione e il cancro. Presso CymitQuimica, offriamo una gamma completa di modulatori dei canali TRP/TRPV per supportare la tua ricerca in biologia sensoriale, gestione del dolore e trasduzione del segnale.
Trovati 96 prodotti di "Canale TRP/TRPV"
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ML204
CAS:ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.Formula:C15H18N2Purezza:98.1% - 99.72%Colore e forma:SolidPeso molecolare:226.32RN-1734
CAS:RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Formula:C14H22Cl2N2O2SPurezza:99.1% - 99.3%Colore e forma:SolidPeso molecolare:353.31AMG 333
CAS:AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.
Formula:C20H12F5N3O4Purezza:99.95%Colore e forma:SolidPeso molecolare:453.32Chembridge-5861528
CAS:Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Formula:C19H23N5O3Purezza:99.97%Colore e forma:SolidPeso molecolare:369.42RQ-00203078
CAS:RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.Formula:C21H13ClF6N2O5SPurezza:98% - 99.6%Colore e forma:SolidPeso molecolare:554.85A-967079
CAS:A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectively
Formula:C12H14FNOPurezza:98.34% - 99.75%Colore e forma:SolidPeso molecolare:207.24ICILIN
CAS:ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.Formula:C16H13N3O4Purezza:98.45% - ≥95%Colore e forma:Light Yellow SolidPeso molecolare:311.29ASP7663
CAS:ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Formula:C14H14FNO3Purezza:98.61%Colore e forma:SolidPeso molecolare:263.26AM-0902
CAS:AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).Formula:C17H15ClN6O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:370.79SB 452533
CAS:SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).Formula:C18H22BrN3OPurezza:99.87%Colore e forma:SolidPeso molecolare:376.29Ref: TM-T23322
2mg39,00€5mg60,00€10mg92,00€25mg173,00€50mg269,00€100mg389,00€200mg555,00€1mL*10mM (DMSO)73,00€PF-4840154
CAS:PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.
Formula:C26H38N6O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:466.62Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Formula:C18H13F6N3O2SPurezza:99.69% - 99.7%Colore e forma:SolidPeso molecolare:449.37SB-705498
CAS:SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.Formula:C17H16BrF3N4OPurezza:99.57% - ≥95%Colore e forma:SolidPeso molecolare:429.23Vanilloid receptor antagonist 1
CAS:Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.Formula:C18H15N3O2Purezza:98.14%Colore e forma:SolidPeso molecolare:305.33Ref: TM-T9247
1mg99,00€5mg235,00€10mg354,00€25mg602,00€50mg847,00€100mg1.206,00€1mL*10mM (DMSO)47,00€AMG9810
CAS:AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.Formula:C21H23NO3Purezza:99.79% - 99.95%Colore e forma:SolidPeso molecolare:337.41Ref: TM-T7189
2mg34,00€5mg48,00€10mg58,00€25mg110,00€50mg177,00€100mg286,00€200mg425,00€1mL*10mM (DMSO)50,00€Optovin
CAS:Optovin is a TRPA1 activator, which is reversibly photoactivated.Formula:C15H13N3OS2Purezza:99.47% - 99.67%Colore e forma:SolidPeso molecolare:315.41Ref: TM-T6617
2mg39,00€5mg57,00€10mg93,00€25mg160,00€50mg250,00€100mg406,00€200mg592,00€1mL*10mM (DMSO)64,00€MDR-652
CAS:MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM forFormula:C22H23ClFN3O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:447.95Ref: TM-T22360
1mg60,00€2mg87,00€5mg130,00€10mg178,00€25mg331,00€50mg512,00€100mg707,00€200mg973,00€1mL*10mM (DMSO)142,00€RN-1747
CAS:RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).Formula:C17H18ClN3O4SPurezza:99.29%Colore e forma:SolidPeso molecolare:395.86AMTB hydrochloride
CAS:AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.Formula:C23H27ClN2O2SPurezza:99.08%Colore e forma:SolidPeso molecolare:430.99Ref: TM-T19723
1mg37,00€5mg79,00€10mg126,00€25mg264,00€50mg449,00€100mg662,00€200mg939,00€1mL*10mM (DMSO)92,00€TRPM8 antagonist 2
CAS:TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.Formula:C26H26N2O2Purezza:98.1%Colore e forma:SolidPeso molecolare:398.5Ref: TM-T5698
1mg34,00€5mg66,00€10mg99,00€25mg167,00€50mg260,00€100mg416,00€200mg600,00€1mL*10mM (DMSO)73,00€
