Canale TRP/TRPV
canali TRP (Transient Receptor Potential), inclusa la sottofamiglia TRPV, sono un gruppo di canali ionici coinvolti in vari processi sensoriali, come la percezione della temperatura, la sensazione del dolore e l'osmoregolazione. I canali TRP sono ampiamente espressi in diversi tessuti e svolgono un ruolo nelle risposte fisiologiche agli stimoli ambientali. In particolare, i canali TRPV sono coinvolti nel rilevamento dei cambiamenti di temperatura e sono implicati in condizioni come il dolore cronico, l'infiammazione e il cancro. Presso CymitQuimica, offriamo una gamma completa di modulatori dei canali TRP/TRPV per supportare la tua ricerca in biologia sensoriale, gestione del dolore e trasduzione del segnale.
Trovati 96 prodotti di "Canale TRP/TRPV"
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AC1903
CAS:AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.Formula:C19H17N3OPurezza:98.45%Colore e forma:SolidPeso molecolare:303.36JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Formula:C19H21F3N2O2Purezza:98.57%Colore e forma:SolidPeso molecolare:366.38Ref: TM-T74779
1mg89,00€5mg204,00€10mg254,00€25mg409,00€50mg624,00€100mg795,00€200mg1.103,00€1mL*10mM (DMSO)225,00€SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Formula:C21H22ClN3OPurezza:99.62% - 99.71%Colore e forma:SolidPeso molecolare:367.87Ref: TM-T12849
1mg67,00€2mg88,00€5mg152,00€10mg236,00€25mg295,00€50mg349,00€100mg439,00€200mg628,00€1mL*10mM (DMSO)166,00€JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Formula:C20H26FN3O2S2Purezza:98.83%Colore e forma:SolidPeso molecolare:423.57Ref: TM-T15634
1mg70,00€5mg187,00€10mg305,00€25mg612,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)173,00€Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Formula:C21H22F5N3O3SPurezza:95.13%Colore e forma:SolidPeso molecolare:491.48TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Formula:C25H23ClF2N4O2Purezza:98%Colore e forma:SolidPeso molecolare:484.93TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Formula:C22H21NO4Purezza:98.16%Colore e forma:SolidPeso molecolare:363.41D-3263 hydrochloride
CAS:<p>D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.</p>Formula:C21H32ClN3O3Purezza:99.93%Colore e forma:SolidPeso molecolare:409.95TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formula:C17H17F3N2O2Purezza:≥98.0%Colore e forma:SolidPeso molecolare:338.32GSK1702934A
CAS:GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Formula:C22H25N3O2SPurezza:98.15%Colore e forma:SolidPeso molecolare:395.52N-Oleoyl Valine
CAS:N-Oleoyl valine, an N-acyl amine, antagonizes TRPV3 for thermoregulation; rises post-cold exposure; elevates in mouse lung injury.Formula:C23H43NO3Peso molecolare:381.59TRPM4-IN-2
CAS:NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.Formula:C19H14ClNO4Purezza:99.21%Colore e forma:SolidPeso molecolare:355.77AM12
CAS:AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).Formula:C15H9BrO5Purezza:98%Colore e forma:SolidPeso molecolare:349.13RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Formula:C21H23F3N4O5SPurezza:99.99%Colore e forma:SolidPeso molecolare:500.49HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Formula:C22H20Cl2N4O4Purezza:98.48%Colore e forma:SolidPeso molecolare:475.32Ref: TM-T15465
1mg88,00€5mg169,00€10mg250,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)168,00€ABT 102
CAS:ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.Formula:C21H24N4OPurezza:98.38% - 99.86%Colore e forma:SolidPeso molecolare:348.44Ref: TM-T29522
1mg109,00€5mg235,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€1mL*10mM (DMSO)245,00€Olvanil
CAS:Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Formula:C26H43NO3Purezza:99.58%Colore e forma:SolidPeso molecolare:417.62Ref: TM-T23106
2mg34,00€5mg49,00€10mg75,00€25mg145,00€50mg236,00€100mg385,00€200mg560,00€1mL*10mM (DMSO)50,00€Elismetrep
CAS:Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.Formula:C27H21F3N2O5SPurezza:99.37% - 99.93%Colore e forma:SolidPeso molecolare:542.53TC-I 2014
CAS:TC-I 2014 shows antiallodynic properties in pain models.Formula:C23H19F6N3OPurezza:99.07%Colore e forma:SolidPeso molecolare:467.41Ref: TM-T17006
1mg60,00€5mg127,00€10mg202,00€25mg406,00€50mg655,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)133,00€MSP3
CAS:MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Formula:C16H19NO3SPurezza:99.89%Colore e forma:SolidPeso molecolare:305.39Ref: TM-T28118
2mg34,00€5mg52,00€10mg85,00€25mg170,00€50mg255,00€100mg378,00€200mg533,00€1mL*10mM (DMSO)74,00€
