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Glucokinasi

Glucokinasi

La glucocinasi (GK) è un enzima che catalizza la fosforilazione del glucosio a glucosio-6-fosfato, un passaggio critico nella glicolisi. La GK è espressa principalmente nel fegato e nel pancreas, dove svolge un ruolo chiave nella regolazione dei livelli di glucosio nel sangue. Gli inibitori della GK sono di interesse nello studio dei disturbi metabolici come il diabete, poiché possono modulare il metabolismo del glucosio e la secrezione di insulina. Presso CymitQuimica, offriamo inibitori della glucocinasi per supportare la tua ricerca sul diabete, il metabolismo e lo sviluppo terapeutico.

Trovati 57 prodotti di "Glucokinasi"

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  • MK-0941 free base

    CAS:
    MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.
    Formula:C21H24N4O6S
    Purezza:98.75%
    Colore e forma:Solid
    Peso molecolare:460.5

    Ref: TM-T12056

    1mg
    87,00€
    5mg
    172,00€
    10mg
    258,00€
    25mg
    425,00€
    50mg
    598,00€
    100mg
    810,00€
    1mL*10mM (DMSO)
    208,00€
  • Dorzagliatin

    CAS:
    Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
    Formula:C22H27ClN4O5
    Purezza:98.67% - 99.45%
    Colore e forma:Solid
    Peso molecolare:462.93

    Ref: TM-T15159

    1mg
    38,00€
    2mg
    50,00€
    5mg
    82,00€
    10mg
    116,00€
    25mg
    227,00€
    50mg
    358,00€
    100mg
    537,00€
    1mL*10mM (DMSO)
    90,00€
  • Oxfendazole

    CAS:
    Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.
    Formula:C15H13N3O3S
    Purezza:98.99% - 99.17%
    Colore e forma:White To Yellowish Powder
    Peso molecolare:315.35

    Ref: TM-T0714

    1g
    70,00€
    5g
    127,00€
    10g
    187,00€
    200mg
    37,00€
    500mg
    50,00€
    1mL*10mM (DMSO)
    34,00€
  • WAY-640509

    CAS:
    WAY-640509 is a glucocerebrosidase inhibitor.
    Formula:C25H23N5O4S
    Purezza:99.36%
    Colore e forma:Solid
    Peso molecolare:489.55

    Ref: TM-T60048

    1mg
    115,00€
    2mg
    172,00€
    5mg
    255,00€
    10mg
    375,00€
    25mg
    562,00€
    50mg
    787,00€
    100mg
    1.074,00€
    500mg
    2.157,00€
  • MitoPQ

    CAS:
    MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.
    Formula:C39H46I3N2P
    Purezza:99.87% - 99.91%
    Colore e forma:Solid
    Peso molecolare:954.48

    Ref: TM-T33412

    1mg
    46,00€
    5mg
    92,00€
    10mg
    144,00€
    25mg
    215,00€
    50mg
    340,00€
    100mg
    535,00€
  • KAN0438757

    CAS:

    KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.

    Formula:C21H18FNO7S
    Purezza:99.34%
    Colore e forma:Solid
    Peso molecolare:447.43

    Ref: TM-T11741

    1mg
    101,00€
    5mg
    192,00€
    10mg
    306,00€
    25mg
    553,00€
    50mg
    760,00€
    100mg
    1.035,00€
  • ML251

    CAS:
    ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.
    Formula:C17H13Cl2N3O4S
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:426.27

    Ref: TM-T64320

    1mg
    115,00€
    5mg
    274,00€
    10mg
    432,00€
    25mg
    715,00€
    50mg
    1.008,00€
    100mg
    1.359,00€
    200mg
    1.825,00€
    1mL*10mM (DMSO)
    301,00€
  • WAY-615145

    CAS:
    WAY-615145 is a compound that activates glucokinase.
    Formula:C16H18N2OS
    Colore e forma:Solid
    Peso molecolare:286.39

    Ref: TM-T202189

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • ML266

    CAS:
    ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.
    Formula:C24H22BrN3O4
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:496.35

    Ref: TM-T8990

    1mg
    50,00€
    2mg
    71,00€
    5mg
    105,00€
    10mg
    166,00€
    25mg
    325,00€
    50mg
    449,00€
    100mg
    652,00€
    500mg
    1.369,00€
    1mL*10mM (DMSO)
    114,00€
  • AP-III-a4 hydrochloride

    CAS:
    AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.
    Formula:C31H44ClFN8O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:631.18

    Ref: TM-T6759L

    2mg
    97,00€
    5mg
    178,00€
    10mg
    286,00€
    25mg
    588,00€
    50mg
    830,00€
    100mg
    Prezzo su richiesta
    200mg
    Prezzo su richiesta
    1mL*10mM (DMSO)
    248,00€
  • ADP-specific glucokinase

    CAS:
    ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.
    Colore e forma:Solid

    Ref: TM-T89882

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Neuron-specific enolase, Human


    Neuron-specific enolase, Human (EC 4.2.1.11), is an enolase enzyme that serves as a biomarker for traumatic brain injury (TBI), stroke following cardiac arrest, hypoxic encephalopathy, and acute spinal cord injury (SCI).
    Colore e forma:Odour Solid

    Ref: TM-TRP-00595

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • (1S,2R)-Globalagliatin

    CAS:
    (1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.
    Formula:C28H37N3O3S3
    Purezza:99.09% - 99.17%
    Colore e forma:Soild
    Peso molecolare:559.81

    Ref: TM-T3104L

    1mg
    34,00€
    5mg
    74,00€
    10mg
    99,00€
    25mg
    164,00€
    50mg
    234,00€
  • PF-04991532

    CAS:
    PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.
    Formula:C18H19F3N4O3
    Purezza:99.99%
    Colore e forma:Solid
    Peso molecolare:396.36

    Ref: TM-T16480

    1mg
    47,00€
    2mg
    62,00€
    5mg
    92,00€
    10mg
    155,00€
    25mg
    250,00€
    50mg
    369,00€
    1mL*10mM (DMSO)
    101,00€
  • Cadisegliatin

    CAS:
    Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.
    Formula:C21H33N3O4S2
    Colore e forma:Solid
    Peso molecolare:455.63

    Ref: TM-T62821

    25mg
    825,00€
    50mg
    1.071,00€
    100mg
    1.674,00€
  • Anti-Glucokinase Antibody (3U461)


    Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.
    Colore e forma:Odour Liquid

    Ref: TM-TMAY-01610

    100µl
    263,00€
  • 5MPN

    CAS:
    5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.
    Formula:C15H19N3O4
    Purezza:98.92% - 99.69%
    Colore e forma:Solid
    Peso molecolare:305.33

    Ref: TM-T40565

    2mg
    92,00€
    5mg
    160,00€
    10mg
    260,00€
    25mg
    522,00€
    50mg
    835,00€
    100mg
    1.341,00€
    200mg
    1.773,00€
    1mL*10mM (DMSO)
    170,00€
  • Anti-Glucokinase Antibody (5Q209)


    Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.
    Colore e forma:Odour Liquid

    Ref: TM-TMAY-01609

    100µl
    193,00€
  • Hex

    CAS:
    Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.
    Formula:C5H10NO5P
    Colore e forma:Solid
    Peso molecolare:195.11

    Ref: TM-T39419

    1mg
    369,00€
  • Glucokinase Protein, Human, Recombinant


    Glucokinase belongs to the bacterial glucokinase family.
    Colore e forma:Lyophilized Powder
    Peso molecolare:52.2 kDa (predicted); 52.2 kDa (reducing conditions)

    Ref: TM-TMPY-04394

    5µg
    94,00€
    10µg
    153,00€
    20µg
    242,00€
    50µg
    554,00€