Glucokinasi
La glucocinasi (GK) è un enzima che catalizza la fosforilazione del glucosio a glucosio-6-fosfato, un passaggio critico nella glicolisi. La GK è espressa principalmente nel fegato e nel pancreas, dove svolge un ruolo chiave nella regolazione dei livelli di glucosio nel sangue. Gli inibitori della GK sono di interesse nello studio dei disturbi metabolici come il diabete, poiché possono modulare il metabolismo del glucosio e la secrezione di insulina. Presso CymitQuimica, offriamo inibitori della glucocinasi per supportare la tua ricerca sul diabete, il metabolismo e lo sviluppo terapeutico.
Trovati 56 prodotti di "Glucokinasi"
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MK-0941 free base
CAS:MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.Formula:C21H24N4O6SPurezza:98.75%Colore e forma:SolidPeso molecolare:460.5Dorzagliatin
CAS:Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.Formula:C22H27ClN4O5Purezza:98.67% - 99.45%Colore e forma:SolidPeso molecolare:462.93Oxfendazole
CAS:Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.Formula:C15H13N3O3SPurezza:98.99% - 99.17%Colore e forma:White To Yellowish PowderPeso molecolare:315.35WAY-640509
CAS:<p>WAY-640509 is a glucocerebrosidase inhibitor.</p>Formula:C25H23N5O4SPurezza:99.36%Colore e forma:SolidPeso molecolare:489.55MitoPQ
CAS:MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.Formula:C39H46I3N2PPurezza:99.87% - 99.91%Colore e forma:SolidPeso molecolare:954.48KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Formula:C21H18FNO7SPurezza:99.34%Colore e forma:SolidPeso molecolare:447.43ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formula:C17H13Cl2N3O4SPurezza:99.87%Colore e forma:SolidPeso molecolare:426.27WAY-615145
CAS:WAY-615145 is a compound that activates glucokinase.Formula:C16H18N2OSPeso molecolare:286.39ML266
CAS:<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Formula:C24H22BrN3O4Purezza:99.58%Colore e forma:SolidPeso molecolare:496.35AP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Formula:C31H44ClFN8O3Purezza:98%Colore e forma:SolidPeso molecolare:631.18ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Colore e forma:SolidNeuron-specific enolase, Human
Neuron-specific enolase, Human (EC 4.2.1.11), is an enolase enzyme that serves as a biomarker for traumatic brain injury (TBI), stroke following cardiac arrest, hypoxic encephalopathy, and acute spinal cord injury (SCI).Colore e forma:Odour Solid(1S,2R)-Globalagliatin
CAS:(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.Formula:C28H37N3O3S3Purezza:99.09% - 99.17%Colore e forma:SoildPeso molecolare:559.81PF-04991532
CAS:PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.Formula:C18H19F3N4O3Purezza:99.99%Colore e forma:SolidPeso molecolare:396.36Cadisegliatin
CAS:Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.Formula:C21H33N3O4S2Colore e forma:SolidPeso molecolare:455.63Anti-Glucokinase Antibody (3U461)
Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.Colore e forma:Odour Liquid5MPN
CAS:<p>5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.</p>Formula:C15H19N3O4Purezza:98.92% - 99.69%Colore e forma:SolidPeso molecolare:305.33Anti-Glucokinase Antibody (5Q209)
<p>Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.</p>Colore e forma:Odour LiquidHex
CAS:Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.Formula:C5H10NO5PColore e forma:SolidPeso molecolare:195.11Glucokinase Protein, Human, Recombinant
<p>Glucokinase belongs to the bacterial glucokinase family.</p>Colore e forma:Lyophilized PowderPeso molecolare:52.2 kDa (predicted); 52.2 kDa (reducing conditions)
