Prolil-idrossilasi HIF/HIF
Il fattore inducibile dall'ipossia (HIF) è un fattore di trascrizione che svolge un ruolo cruciale nelle risposte cellulari ai bassi livelli di ossigeno (ipossia). L'attività di HIF è strettamente regolata dalle prolyl-idrossilasi HIF, che bersagliano HIF per la degradazione in condizioni normossiche. Gli inibitori della prolyl-idrossilasi HIF possono stabilizzare HIF, promuovendo l'espressione di geni coinvolti nell'angiogenesi, eritropoiesi e metabolismo. Questi inibitori sono di grande interesse per il trattamento di condizioni come anemia, malattie ischemiche e cancro. Presso CymitQuimica, offriamo inibitori di HIF/prolyl-idrossilasi HIF per supportare la tua ricerca in biologia dell'ipossia, terapia anticancro e regolazione metabolica.
Trovati 146 prodotti di "Prolil-idrossilasi HIF/HIF"
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Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormula:C6H13Li3O11Purezza:99.88%Colore e forma:White Crystalline PowderPeso molecolare:281.98Roxadustat
CAS:Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.Formula:C19H16N2O5Purezza:99% - 99.88%Colore e forma:SolidPeso molecolare:352.34Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formula:C6H13NO5·HClPurezza:99.77%Colore e forma:White Solid CrystallinePeso molecolare:215.63Hydroxycitric acid tripotassium hydrate
CAS:Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits HIF, has antioxidation, anti-inflammation, and anti-tumor effects.Formula:C6H7K3O8Purezza:99.85%Colore e forma:White Solid CrystallinePeso molecolare:324.41Tilorone dihydrochloride
CAS:<p>Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.</p>Formula:C25H36Cl2N2O3Purezza:98% - 99.86%Colore e forma:Orange Yellow Crystal PowderPeso molecolare:483.47Glucosamine
CAS:<p>Glucosamine (Chitosamine) is used as a dietary supplement. Glucosamine has pharmacological effects on osteoarthritis cartilage. High-Quality, Low-Cost!</p>Formula:C6H13NO5Purezza:99.8% - 99.8%Colore e forma:CoaPeso molecolare:179.17Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurezza:99.59%Colore e forma:White SolidPeso molecolare:214.22Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurezza:98.21% - 98.76%Colore e forma:Colorless Crystals SolidPeso molecolare:265.33(-)-Hydroxycitric acid lactone
CAS:(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, whichFormula:C6H6O7Purezza:99.91%Colore e forma:SolidPeso molecolare:190.11EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Formula:C28H35NO3Purezza:98.36%Colore e forma:SolidPeso molecolare:433.58Ref: TM-T13289
1mg107,00€5mg227,00€10mg378,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)250,00€Chloramphenicol
CAS:<p>Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.</p>Formula:C11H12Cl2N2O5Purezza:99.6% - 99.84%Colore e forma:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidPeso molecolare:323.13SYP-5
CAS:SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.Formula:C18H16O3SPurezza:98.31%Colore e forma:SolidPeso molecolare:312.38Enarodustat
CAS:<p>Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.</p>Formula:C17H16N4O4Purezza:99.73% - 99.75%Colore e forma:SolidPeso molecolare:340.33HIF-2α-IN-2
CAS:HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).Formula:C17H13F2NO4SPurezza:99.24%Colore e forma:SolidPeso molecolare:365.35Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purezza:99.28% - >99.99%Colore e forma:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecolare:493.94PT2399
CAS:PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.Formula:C17H10F5NO4SPurezza:98.8% - 99.45%Colore e forma:SolidPeso molecolare:419.32Ref: TM-T12675L
1mg94,00€5mg224,00€10mg335,00€25mg607,00€50mg895,00€100mg1.254,00€1mL*10mM (DMSO)245,00€Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formula:C26H52N6O11SPurezza:94.68% - 99.8%Colore e forma:SolidPeso molecolare:656.79Hydralazine hydrochloride
CAS:Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Formula:C8H9ClN4Purezza:99.85% - 99.86%Colore e forma:Yellow Crystals White Crystalline SolidPeso molecolare:196.64Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formula:C8H6N2S3Purezza:98.79% - 99.77%Colore e forma:SolidPeso molecolare:226.34Vadadustat
CAS:Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.Formula:C14H11ClN2O4Purezza:99.02% - 99.80%Colore e forma:SolidPeso molecolare:306.7
