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Anidrasi carbonica

Anidrasi carbonica

L'anidrasi carbonica è un enzima che catalizza la conversione reversibile del diossido di carbonio e acqua in bicarbonato e protoni. Questo enzima svolge un ruolo cruciale nel mantenimento dell'equilibrio acido-base, nella respirazione e nel trasporto di anidride carbonica nel sangue. Gli inibitori dell'anidrasi carbonica sono utilizzati nel trattamento del glaucoma, dell'epilessia e del mal di montagna, nonché nella ricerca sull'omeostasi acido-base e lo scambio gassoso. Presso CymitQuimica, offriamo una gamma di inibitori dell'anidrasi carbonica e reagenti di alta qualità per supportare la tua ricerca in enzimologia, fisiologia respiratoria e sviluppo terapeutico.

Trovati 188 prodotti di "Anidrasi carbonica"

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  • pNNP

    CAS:
    pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.
    Formula:C6H6NO6P
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:219.09
  • Tioxolone

    CAS:
    Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
    Formula:C7H4O3S
    Purezza:97.79%
    Colore e forma:Light Yellow To Beige Powder
    Peso molecolare:168.17
  • Brinzolamide

    CAS:
    <p>Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.</p>
    Formula:C12H21N3O5S3
    Purezza:99.84% - >99.99%
    Colore e forma:Crystalline Solid
    Peso molecolare:383.51
  • Zonisamide

    CAS:
    <p>Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.</p>
    Formula:C8H8N2O3S
    Purezza:99.05% - 99.9%
    Colore e forma:Off-White Powder
    Peso molecolare:212.23
  • Methocarbamol

    CAS:
    Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.
    Formula:C11H15NO5
    Purezza:99.96%
    Colore e forma:Crystals From Benzene Solid
    Peso molecolare:241.24
  • Methazolamide

    CAS:
    Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
    Formula:C5H8N4O3S2
    Purezza:99.31% - 99.77%
    Colore e forma:Crystals From Water Solid
    Peso molecolare:236.27
  • Acipimox

    CAS:
    <p>Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.</p>
    Formula:C6H6N2O3
    Purezza:98.98%
    Colore e forma:Low Yellow Liquid Or Crystalline
    Peso molecolare:154.12
  • Benzthiazide

    CAS:
    <p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>
    Formula:C15H14ClN3O4S3
    Purezza:99.34% - 99.79%
    Colore e forma:Crystals From Acetone Solid
    Peso molecolare:431.94
  • Actarit

    CAS:
    Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.
    Formula:C10H11NO3
    Purezza:99.64% - 99.74%
    Colore e forma:White Or Off-White Crystal Or Crystalline Solid
    Peso molecolare:193.2
  • Topiramate

    CAS:
    <p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>
    Formula:C12H21NO8S
    Purezza:99.79% - 99.92%
    Colore e forma:White To Off-White Crystalline Powder
    Peso molecolare:339.36
  • Carbonic anhydrase inhibitor 15


    <p>Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].</p>
    Formula:C27H33N5O2S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:523.71
  • CAIX/CAXII-IN-4


    <p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>
    Formula:C23H21N5O3S
    Colore e forma:Solid
    Peso molecolare:447.51
  • hCAIX/XII-IN-9


    hCAIX/XII-IN-9 (compound 8) is a potent inhibitor of carbonic anhydrase (CA), with Ki values of 1658 nM for hCA I, 184.8 nM for hCA II, 8.9 nM for hCA IX, and 64.8 nM for hCA XII.
    Formula:C26H25N5O5S2
    Peso molecolare:551.12971
  • CA inhibitor 2


    <p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>
    Formula:C7H9N7O3S3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:335.39
  • 2-Methoxy-4-propylphenol

    CAS:
    <p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>
    Formula:C10H14O2
    Colore e forma:Solid
    Peso molecolare:166.22
  • hCA/VEGFR-2-IN-2


    Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and
    Formula:C23H26N6O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:498.55
  • α-Pyrone

    CAS:
    <p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>
    Formula:C5H4O2
    Colore e forma:Solid
    Peso molecolare:96.08
  • CA IX/VEGFR-2-IN-3


    <p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>
    Formula:C19H16ClN3O5S2
    Colore e forma:Solid
    Peso molecolare:465.93
  • hCA/VEGFR-2-IN-1


    hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (
    Formula:C21H17FN6O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:452.46
  • hCAII/XII-IN-1


    hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.
    Formula:C22H20N4O6S2
    Colore e forma:Solid
    Peso molecolare:500.547
  • CAII/CAXII-IN-1


    CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.
    Colore e forma:Odour Solid
  • Acesulfame

    CAS:
    Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.
    Formula:C4H5NO4S
    Colore e forma:Solid
    Peso molecolare:163.15
  • Carbonic anhydrase inhibitor 18


    <p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>
    Formula:C26H28N4O6S2
    Peso molecolare:556.14503
  • hCAIX/XII-IN-11


    <p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>
    Formula:C13H10FN3O4
    Peso molecolare:291.06553
  • GZ22-4


    <p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>
    Formula:C88H126F3N6NaO24S4
    Peso molecolare:1858.75561
  • Girentuximab

    CAS:
    Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).
    Colore e forma:Liquid
    Peso molecolare:145.55 kDa
  • hCAII/IX-IN-1


    <p>hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.</p>
    Formula:C23H22N4O7S2
    Colore e forma:Solid
    Peso molecolare:530.573
  • 5,6-Dihydro-2H-pyran-2-one

    CAS:
    5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.
    Formula:C5H6O2
    Colore e forma:Solid
    Peso molecolare:98.1
  • hCAII-IN-6


    "hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."
    Formula:C20H25N3O4S
    Colore e forma:Solid
    Peso molecolare:403.5
  • CA Ⅱ-IN-1


    <p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>
    Formula:C18H19NO6S
    Colore e forma:Solid
    Peso molecolare:377.41
  • Carbonic anhydrase inhibitor 30


    Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].
    Formula:C23H22FN3O5S
    Colore e forma:Solid
    Peso molecolare:471.12642
  • hCAIX/XII-IN-10


    hCAIX/XII-IN-10 (compound DK-8) is an inhibitor of Carbonic Anhydrase, showing potent inhibitory activity against the tumor-associated membrane-bound isoforms hCA IX and XII, with Ki values of 32.5 nM and 29.2 nM, respectively.
    Formula:C17H13N3O5S
    Peso molecolare:371.05759
  • Chlorzolamide

    CAS:
    CHLORZOLAMIDE is a sulfonamide-based inhibitor that exhibits cytotoxic effects on prostate cancer cells.
    Formula:C8H6ClN3O2S2
    Peso molecolare:275.74
  • hCA/VEGFR-2-IN-3


    hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.
    Formula:C24H28N6O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:528.58
  • Phenylsulfamide

    CAS:
    <p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>
    Formula:C6H8N2O2S
    Colore e forma:Solid
    Peso molecolare:172.2
  • hCAIX-IN-19


    <p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>
    Colore e forma:Odour Solid
  • TSPO/Carbonic Anhydrase Modulator 1


    TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.
    Formula:C35H51N3O3
    Colore e forma:Solid
    Peso molecolare:561.798
  • hCAIX/XII-IN-14


    hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.
    Formula:C16H14F3N3O4S
    Colore e forma:Solid
    Peso molecolare:401.36
  • Dorzolamide

    CAS:
    <p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>
    Formula:C10H16N2O4S3
    Purezza:98%
    Colore e forma:White Or Almost White Crystalline Powder
    Peso molecolare:324.44
  • Carbonic anhydrase inhibitor 32


    Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.
    Formula:C17H16N6O3S
    Colore e forma:Solid
    Peso molecolare:384.41
  • (E)-Dehydrodiconiferyl alcohol

    CAS:
    (E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.
    Formula:C20H22O6
    Colore e forma:Solid
    Peso molecolare:358.39
  • Carbonic anhydrase inhibitor 31


    Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.
    Formula:C24H20N6O5S
    Colore e forma:Solid
    Peso molecolare:504.12159
  • hCAIX-IN-17


    hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.
    Formula:C19H18N2O3S
    Colore e forma:Solid
    Peso molecolare:354.42
  • VM4-037

    CAS:
    VM4-037 is a PET imaging agent used for carbonic anhydrase IX.
    Formula:C26H29FN6O7S2
    Colore e forma:Solid
    Peso molecolare:620.67
  • hCA/Wnt/β-catenin-IN-1


    <p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>
    Colore e forma:Odour Solid
  • Carbonic anhydrase inhibitor 29


    Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.
    Colore e forma:Odour Solid
  • CAXII-IN-2


    CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.
    Formula:C16H13FNO4P
    Colore e forma:Solid
    Peso molecolare:333.05662
  • hCAII-IN-8

    CAS:
    <p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>
    Formula:C15H16N2O5S
    Purezza:99.73%
    Colore e forma:Soild
    Peso molecolare:336.36
  • hCAI/II-IN-10


    <p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>
    Formula:C24H17Cl2N3O3S2
    Colore e forma:Solid
    Peso molecolare:530.446
  • DPP IV/hCA II-IN-1

    CAS:
    <p>DPP IV/hCA II-IN-1: strong DPP IV &amp; CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>
    Formula:C17H20N2O5S
    Colore e forma:Solid
    Peso molecolare:364.42
  • Bendroflumethiazide

    CAS:
    Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
    Formula:C15H14F3N3O4S2
    Purezza:98% - >99.99%
    Colore e forma:Crystals From Dioxane Solid
    Peso molecolare:421.41
  • Carbonic anhydrase

    CAS:
    <p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>
    Colore e forma:Solid
  • Carbonic anhydrase inhibitor 26


    Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.
    Formula:C17H14N6O4
    Colore e forma:Solid
    Peso molecolare:366.33
  • AV22-149


    AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .
    Formula:C23H28F3N3O6S2
    Colore e forma:Solid
    Peso molecolare:563.61
  • DOTA-XYIMSR-01

    CAS:
    DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.
    Formula:C61H88N16O22S2
    Colore e forma:Solid
    Peso molecolare:1461.57
  • CAIX/CAXII-IN-3


    <p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>
    Colore e forma:Odour Solid
  • α-Glycosidase-IN-2


    α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.
    Formula:C25H22N6OS2
    Colore e forma:Solid
    Peso molecolare:486.61
  • hCAI/II/IV-IN-28

    CAS:
    <p>hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.</p>
    Formula:C14H15N3O3S
    Purezza:96.48%
    Colore e forma:Solid
    Peso molecolare:305.35
  • hCAXII-IN-7


    hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.
    Formula:C26H25N5O6S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:567.64
  • hCAII-IN-7


    hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.
    Formula:C20H25N3O4S
    Colore e forma:Solid
    Peso molecolare:403.5
  • hCAIX/VII-IN-1


    hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.
    Formula:C16H13BFN3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:325.1
  • CAIX Inhibitor S4

    CAS:
    <p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>
    Formula:C15H17N3O4S
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:335.38
  • SH7s


    SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.
    Formula:C24H19ClF3N5O4S
    Colore e forma:Solid
    Peso molecolare:565.95
  • hCA XII-IN-6


    <p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>
    Formula:C11H9N5O3S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:323.35
  • Chlorothiazide

    CAS:
    Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
    Formula:C7H6ClN3O4S2
    Purezza:98.46% - 98.91%
    Colore e forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)
    Peso molecolare:295.72
  • hCAIX/XII-IN-7


    Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for
    Formula:C17H14N6O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:382.4
  • hCA/VEGFR-2-IN-4


    hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/
    Formula:C22H23FN6O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:502.52
  • Pyrocatechol

    CAS:
    Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.
    Formula:C6H6O2
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:110.11
  • M 12325

    CAS:
    M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.
    Formula:C7H5Cl2NO4S
    Colore e forma:White To Almost White Solid Powder
    Peso molecolare:270.09
  • 4-Chloro-3-sulfamoylbenzoic acid

    CAS:
    Compound PDK0044, with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0044 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    Formula:C7H6ClNO4S
    Peso molecolare:235.64
  • Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)


    Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.
    Colore e forma:Lyophilized Powder
    Peso molecolare:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
  • Acetazolamide-d3

    CAS:
    Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.
    Formula:C4H6N4O3S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:225.26
  • Benzolamide

    CAS:
    Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.
    Formula:C8H8N4O4S3
    Purezza:99.31%
    Colore e forma:Solid
    Peso molecolare:320.37
  • Ethoxzolamide

    CAS:
    Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.
    Formula:C9H10N2O3S2
    Purezza:98.27% - 99.62%
    Colore e forma:Crystals From Ethyl Acetate + Skellysolve B Solid
    Peso molecolare:258.32
  • Taselisib

    CAS:
    Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.
    Formula:C24H28N8O2
    Purezza:99.62% - 99.79%
    Colore e forma:Solid
    Peso molecolare:460.53
  • 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

    CAS:
    4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-
    Formula:C7H8F3N3O4S2
    Purezza:98.58%
    Colore e forma:Solid
    Peso molecolare:319.28
  • Indisulam

    CAS:
    <p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>
    Formula:C14H12ClN3O4S2
    Purezza:98.68% - 99.77%
    Colore e forma:Solid
    Peso molecolare:385.85
  • 2,3-dihydro-1H-indene-5-sulfonamide

    CAS:
    2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.
    Formula:C9H11NO2S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:197.25
  • Dorzolamide hydrochloride

    CAS:
    Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that
    Formula:C10H17ClN2O4S3
    Purezza:99.48% - 99.67%
    Colore e forma:White Off-White Crystalline Powder
    Peso molecolare:360.9
  • Methyclothiazide

    CAS:
    <p>Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including</p>
    Formula:C9H11Cl2N3O4S2
    Purezza:99.13%
    Colore e forma:Solid
    Peso molecolare:360.24
  • Zolamide

    CAS:
    <p>Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.</p>
    Formula:C2H4N4O2S2
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:180.21
  • Orthanilamide

    CAS:
    Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.
    Formula:C6H8N2O2S
    Purezza:99.72% - 99.96%
    Colore e forma:White To Pale Cream Crystalline Powder Or Crystals
    Peso molecolare:172.2
  • Brinzolamide hydrochloride


    Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.
    Colore e forma:Solid
  • U-104

    CAS:
    <p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>
    Formula:C13H12FN3O3S
    Purezza:98.76% - 99.88%
    Colore e forma:Solid
    Peso molecolare:309.32
  • Fluorometholone Acetate

    CAS:
    <p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>
    Formula:C24H31FO5
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:418.50
  • Acipimox sodium

    CAS:
    Acipimox sodium is an antilipolytic, enhancing leptin, curbing lipolysis and FFAs, and boosting insulin sensitivity.
    Formula:C6H5N2NaO3
    Colore e forma:Solid
    Peso molecolare:176.11
  • Polmacoxib

    CAS:
    <p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>
    Formula:C18H16FNO4S
    Purezza:97.88%
    Colore e forma:Solid
    Peso molecolare:361.39
  • 4-(benzyloxy)benzene-1-sulfonamide

    CAS:
    4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.
    Formula:C13H13NO3S
    Purezza:97.54%
    Colore e forma:Solid
    Peso molecolare:263.31
  • Dichlorphenamide

    CAS:
    Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
    Formula:C6H6Cl2N2O4S2
    Purezza:96.87% - 97.25%
    Colore e forma:Needles From Dimethylsulfoxide + Water Solid
    Peso molecolare:305.16
  • Dimethylfraxetin

    CAS:
    Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
    Formula:C12H12O5
    Purezza:99.96% - ≥95%
    Colore e forma:Solid
    Peso molecolare:236.22
  • EMAC10101d

    CAS:
    <p>compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an</p>
    Formula:C17H15Cl2N3O2S2
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:428.36
  • Dichlorphenamide disodium

    CAS:
    <p>Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.</p>
    Formula:C6H6Cl2N2Na2O4S2
    Colore e forma:Solid
    Peso molecolare:351.12
  • Benzenesulfonamide

    CAS:
    Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.
    Formula:C6H7NO2S
    Purezza:99.42% - 99.99%
    Colore e forma:White Crystalline Powder
    Peso molecolare:157.19
  • Trichlormethiazide sodium

    CAS:
    Trichlormethiazide sodium: oral thiazide diuretic, antihypertensive, boosts urine, Na/K excretion, may enhance renal clearance.
    Formula:C8H8Cl3N3NaO4S2
    Colore e forma:Solid
    Peso molecolare:403.63
  • Methazolamide-d6

    CAS:
    <p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>
    Formula:C5H2D6N4O3S2
    Colore e forma:Solid
    Peso molecolare:242.31
  • Disulfamide

    CAS:
    <p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>
    Formula:C7H9ClN2O4S2
    Purezza:98.1%
    Colore e forma:Solid
    Peso molecolare:284.74
  • HCAIX-IN-2

    CAS:
    HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).
    Formula:C19H16N8O4S
    Colore e forma:Solid
    Peso molecolare:452.45
  • hCAIX-IN-11

    CAS:
    <p>hCAIX-IN-11 inhibits carbonic anhydrases IX &amp; XII with Ki of 32.7 nM &amp; 623.5 nM, respectively.</p>
    Formula:C21H15ClN4O3
    Colore e forma:Solid
    Peso molecolare:406.82
  • hCAI/II-IN-1

    CAS:
    <p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>
    Formula:C18H29N5O3S3
    Colore e forma:Solid
    Peso molecolare:459.65
  • hCAIX/XII-IN-2

    CAS:
    Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).
    Formula:C19H14N2O4
    Colore e forma:Solid
    Peso molecolare:334.33