Anidrasi carbonica
L'anidrasi carbonica è un enzima che catalizza la conversione reversibile del diossido di carbonio e acqua in bicarbonato e protoni. Questo enzima svolge un ruolo cruciale nel mantenimento dell'equilibrio acido-base, nella respirazione e nel trasporto di anidride carbonica nel sangue. Gli inibitori dell'anidrasi carbonica sono utilizzati nel trattamento del glaucoma, dell'epilessia e del mal di montagna, nonché nella ricerca sull'omeostasi acido-base e lo scambio gassoso. Presso CymitQuimica, offriamo una gamma di inibitori dell'anidrasi carbonica e reagenti di alta qualità per supportare la tua ricerca in enzimologia, fisiologia respiratoria e sviluppo terapeutico.
Trovati 197 prodotti di "Anidrasi carbonica"
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Benzthiazide
CAS:<p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>Formula:C15H14ClN3O4S3Purezza:99.34% - 99.79%Colore e forma:Crystals From Acetone SolidPeso molecolare:431.94Brinzolamide
CAS:Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Formula:C12H21N3O5S3Purezza:99.84% - >99.99%Colore e forma:Crystalline SolidPeso molecolare:383.51pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Formula:C6H6NO6PPurezza:99.82%Colore e forma:SolidPeso molecolare:219.09Methazolamide
CAS:Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Formula:C5H8N4O3S2Purezza:99.31% - 99.77%Colore e forma:Crystals From Water SolidPeso molecolare:236.27Zonisamide
CAS:Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Formula:C8H8N2O3SPurezza:99.05% - 99.9%Colore e forma:Off-White PowderPeso molecolare:212.23Acipimox
CAS:Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.Formula:C6H6N2O3Purezza:98.98%Colore e forma:Low Yellow Liquid Or CrystallinePeso molecolare:154.12Topiramate
CAS:<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formula:C12H21NO8SPurezza:99.79% - 99.92%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:339.36Tioxolone
CAS:Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Formula:C7H4O3SPurezza:97.79%Colore e forma:Light Yellow To Beige PowderPeso molecolare:168.17Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formula:C11H15NO5Purezza:99.96%Colore e forma:Crystals From Benzene SolidPeso molecolare:241.24Actarit
CAS:Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.Formula:C10H11NO3Purezza:99.64% - 99.74%Colore e forma:White Or Off-White Crystal Or Crystalline SolidPeso molecolare:193.2hCA/VEGFR-2-IN-1
hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (Formula:C21H17FN6O3SPurezza:98%Colore e forma:SolidPeso molecolare:452.46hCAIX/XII-IN-9
hCAIX/XII-IN-9 (compound 8) is a potent inhibitor of carbonic anhydrase (CA), with Ki values of 1658 nM for hCA I, 184.8 nM for hCA II, 8.9 nM for hCA IX, and 64.8 nM for hCA XII.Formula:C26H25N5O5S2Peso molecolare:551.12971hCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Formula:C24H28N6O6SPurezza:98%Colore e forma:SolidPeso molecolare:528.58Carbonic anhydrase
CAS:<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Colore e forma:SolidCAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formula:C15H17N3O4SPurezza:99.07%Colore e forma:SolidPeso molecolare:335.38Chlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formula:C7H6ClN3O4S2Purezza:98.46% - 98.91%Colore e forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecolare:295.72Pyrocatechol
CAS:Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Formula:C6H6O2Purezza:99.96%Colore e forma:SolidPeso molecolare:110.11hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Formula:C15H16N2O5SPurezza:99.73%Colore e forma:SoildPeso molecolare:336.36DOTA-XYIMSR-01
CAS:DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formula:C61H88N16O22S2Colore e forma:SolidPeso molecolare:1461.57CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Colore e forma:Odour SolidhCA XII-IN-6
Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferativeFormula:C11H9N5O3S2Purezza:98%Colore e forma:SolidPeso molecolare:323.35hCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFormula:C17H14N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:382.4hCAI/II/IV-IN-28
CAS:hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.Formula:C14H15N3O3SPurezza:98.25%Colore e forma:SolidPeso molecolare:305.35hCAXII-IN-7
hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.Formula:C26H25N5O6S2Purezza:98%Colore e forma:SolidPeso molecolare:567.645,6-Dihydro-2H-pyran-2-one
CAS:5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Formula:C5H6O2Colore e forma:SolidPeso molecolare:98.1Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Formula:C23H22FN3O5SColore e forma:SolidPeso molecolare:471.12642hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Colore e forma:Odour SolidhCAIX/VII-IN-1
hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.Formula:C16H13BFN3O3Purezza:98%Colore e forma:SolidPeso molecolare:325.1CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Formula:C23H21N5O3SColore e forma:SolidPeso molecolare:447.51CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Formula:C19H16ClN3O5S2Colore e forma:SolidPeso molecolare:465.932-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formula:C10H14O2Colore e forma:SolidPeso molecolare:166.22hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFormula:C23H26N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:498.55α-Pyrone
CAS:<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Formula:C5H4O2Colore e forma:SolidPeso molecolare:96.08Carbonic anhydrase inhibitor 15
Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].Formula:C27H33N5O2S2Purezza:98%Colore e forma:SolidPeso molecolare:523.71hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Formula:C22H23FN6O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.52CA inhibitor 2
<p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>Formula:C7H9N7O3S3Purezza:98%Colore e forma:SolidPeso molecolare:335.39TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Formula:C35H51N3O3Colore e forma:SolidPeso molecolare:561.798hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Formula:C16H14F3N3O4SColore e forma:SolidPeso molecolare:401.36Dorzolamide
CAS:<p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>Formula:C10H16N2O4S3Purezza:98%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:324.44SH7s
SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.Formula:C24H19ClF3N5O4SColore e forma:SolidPeso molecolare:565.95Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formula:C17H16N6O3SColore e forma:SolidPeso molecolare:384.41(E)-Dehydrodiconiferyl alcohol
CAS:(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.Formula:C20H22O6Colore e forma:SolidPeso molecolare:358.39Carbonic anhydrase inhibitor 31
Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.Formula:C24H20N6O5SColore e forma:SolidPeso molecolare:504.12159hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Formula:C19H18N2O3SColore e forma:SolidPeso molecolare:354.42VM4-037
CAS:VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Formula:C26H29FN6O7S2Colore e forma:SolidPeso molecolare:620.67hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Colore e forma:Odour SolidCarbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Colore e forma:Odour SolidCAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Formula:C16H13FNO4PColore e forma:SolidPeso molecolare:333.05662hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Formula:C24H17Cl2N3O3S2Colore e forma:SolidPeso molecolare:530.446DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formula:C17H20N2O5SColore e forma:SolidPeso molecolare:364.42Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purezza:98% - >99.99%Colore e forma:Crystals From Dioxane SolidPeso molecolare:421.41hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5CAIX-IN-4
CAIX-IN-4 (Compound 8b) is a selective inhibitor of carbonic anhydrase IX (CAIX) with an IC50 value of 0.32 μM. It holds potential for research in cancer, such as renal cell carcinoma.Colore e forma:Odour SolidhCA-I/hCA-II-IN-1
hCA-I/hCA-II-IN-1 (Compound P4) is a potent dual inhibitor of human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II), with Ki values of 0.22 μM and 0.33 μM respectively. hCA-I/hCA-II-IN-1 is useful for research into diseases related to CA enzymes, including glaucoma, hypertension, and ulcers.Colore e forma:Odour SolidCarbonic anhydrase inhibitor 26
Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.Formula:C17H14N6O4Colore e forma:SolidPeso molecolare:366.33Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formula:C6H8N2O2SColore e forma:SolidPeso molecolare:172.2AV22-149
AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .Formula:C23H28F3N3O6S2Colore e forma:SolidPeso molecolare:563.61α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formula:C25H22N6OS2Colore e forma:SolidPeso molecolare:486.61CA Ⅱ-IN-1
CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.Formula:C18H19NO6SColore e forma:SolidPeso molecolare:377.41hCAXII-IN-9
hCAXII-IN-9 (Compound 3I) is a selective hCAXII inhibitor with Ki values of 28 nM for hCAXII, 7192.6 nM for hCAI, 188.6 nM for hCAII, and greater than 100000 nM for hCAIX. This compound may be utilized in anti-tumor research.Formula:C24H30N3O7PSPeso molecolare:535.15421(Iso)-Samixogrel
CAS:(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Formula:C25H25ClN2O4SPurezza:98.85%Colore e forma:SolidPeso molecolare:484.99Carbonic anhydrase inhibitor 24
Carbonic anhydrase inhibitor24 (Compound 11) is an inhibitor of human carbonic anhydrase. It exhibits Ki values of 10.7 nM and 7.5 nM against hCAs IX and XII, respectively.Formula:C16H14Cl2N2O6SPeso molecolare:431.99496Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formula:C4H5NO4SColore e forma:SolidPeso molecolare:163.15Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formula:C26H28N4O6S2Peso molecolare:556.14503Carbonic anhydrase inhibitor 21
Compound 5h, known as Carbonic anhydrase inhibitor 21, is a specific inhibitor of carbonic anhydrase (hCA IX) with a K\(_i\) of 15.1 nM, demonstrating high selectivity compared to other isoforms studied. This compound is utilized in anticancer research.Formula:C32H48N4O10P2S2Peso molecolare:774.22871hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formula:C13H10FN3O4Peso molecolare:291.06553Chlorthalidone Impurity G
CAS:Chlorthalidone impurity G, a thiazide-like diuretic's contaminant, has mild antihypertensive properties and inhibits several carbonic anhydrase isoforms.Formula:C14H9Cl2NO2Colore e forma:SolidPeso molecolare:294.13GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Formula:C88H126F3N6NaO24S4Peso molecolare:1858.75561Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Colore e forma:LiquidPeso molecolare:145.55 kDahCAIX/XII-IN-10
hCAIX/XII-IN-10 (compound DK-8) is an inhibitor of Carbonic Anhydrase, showing potent inhibitory activity against the tumor-associated membrane-bound isoforms hCA IX and XII, with Ki values of 32.5 nM and 29.2 nM, respectively.Formula:C17H13N3O5SPeso molecolare:371.05759CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Colore e forma:Odour SolidChlorzolamide
CAS:CHLORZOLAMIDE is a sulfonamide-based inhibitor that exhibits cytotoxic effects on prostate cancer cells.Formula:C8H6ClN3O2S2Peso molecolare:275.74hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formula:C22H20N4O6S2Colore e forma:SolidPeso molecolare:500.547hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formula:C23H22N4O7S2Colore e forma:SolidPeso molecolare:530.573M 12325
CAS:M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.Formula:C7H5Cl2NO4SColore e forma:White To Almost White Solid PowderPeso molecolare:270.09Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Colore e forma:Lyophilized PowderPeso molecolare:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Acetazolamide-d3
CAS:Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.Formula:C4H6N4O3S2Purezza:98%Colore e forma:SolidPeso molecolare:225.26Trichlormethiazide (Standard)
CAS:Trichlormethiazide (Standard) is the standard substance of Trichlormethiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.Formula:C8H8Cl3N3O4S2Peso molecolare:380.664-Chloro-3-sulfamoylbenzoic acid
CAS:Compound PDK0044, with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0044 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H6ClNO4SPeso molecolare:235.642,3-dihydro-1H-indene-5-sulfonamide
CAS:2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.Formula:C9H11NO2SPurezza:99.89%Colore e forma:SolidPeso molecolare:197.25Ref: TM-T8611
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)104,00€Ethoxzolamide
CAS:Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.Formula:C9H10N2O3S2Purezza:98.27% - 99.62%Colore e forma:Crystals From Ethyl Acetate + Skellysolve B SolidPeso molecolare:258.32Fluorometholone Acetate
CAS:Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.Formula:C24H31FO5Purezza:99.76%Colore e forma:SolidPeso molecolare:418.50Dichlorphenamide
CAS:Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.Formula:C6H6Cl2N2O4S2Purezza:96.87% - 97.25%Colore e forma:Needles From Dimethylsulfoxide + Water SolidPeso molecolare:305.16Ref: TM-T6469
5mg50,00€10mg65,00€25mg87,00€50mg96,00€100mg140,00€200mg202,00€500mg340,00€1mL*10mM (DMSO)59,00€4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-Formula:C7H8F3N3O4S2Purezza:98.58%Colore e forma:SolidPeso molecolare:319.28Brinzolamide hydrochloride
Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.Colore e forma:SolidU-104
CAS:<p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>Formula:C13H12FN3O3SPurezza:98.76% - 99.88%Colore e forma:SolidPeso molecolare:309.32Dimethylfraxetin
CAS:Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)Formula:C12H12O5Purezza:99.96% - ≥95%Colore e forma:SolidPeso molecolare:236.22Dichlorphenamide disodium
CAS:Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.Formula:C6H6Cl2N2Na2O4S2Colore e forma:SolidPeso molecolare:351.12Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formula:C6H8N2O2SPurezza:99.72% - 99.96%Colore e forma:White To Pale Cream Crystalline Powder Or CrystalsPeso molecolare:172.2Trichlormethiazide sodium
CAS:Trichlormethiazide sodium: oral thiazide diuretic, antihypertensive, boosts urine, Na/K excretion, may enhance renal clearance.Formula:C8H8Cl3N3NaO4S2Colore e forma:SolidPeso molecolare:403.63Taselisib
CAS:Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.Formula:C24H28N8O2Purezza:99.62% - 99.79%Colore e forma:SolidPeso molecolare:460.53Ref: TM-T1999
2mg46,00€5mg66,00€10mg92,00€25mg157,00€50mg197,00€100mg350,00€200mg522,00€500mg840,00€1mL*10mM (DMSO)66,00€Zolamide
CAS:Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.Formula:C2H4N4O2S2Purezza:99.75%Colore e forma:SolidPeso molecolare:180.21Acipimox sodium
CAS:Acipimox sodium is an antilipolytic, enhancing leptin, curbing lipolysis and FFAs, and boosting insulin sensitivity.Formula:C6H5N2NaO3Colore e forma:SolidPeso molecolare:176.11Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurezza:99.42% - 99.99%Colore e forma:White Crystalline PowderPeso molecolare:157.19Dorzolamide hydrochloride
CAS:Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme thatFormula:C10H17ClN2O4S3Purezza:99.48% - 99.67%Colore e forma:White Off-White Crystalline PowderPeso molecolare:360.9Methyclothiazide
CAS:Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions includingFormula:C9H11Cl2N3O4S2Purezza:99.13%Colore e forma:SolidPeso molecolare:360.24Polmacoxib
CAS:Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.Formula:C18H16FNO4SPurezza:97.88%Colore e forma:SolidPeso molecolare:361.39Ref: TM-T21294
2mg47,00€5mg70,00€10mg107,00€25mg173,00€50mg259,00€100mg378,00€200mg563,00€1mL*10mM (DMSO)77,00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purezza:98.68% - 99.77%Colore e forma:SolidPeso molecolare:385.85Ref: TM-T4321
1mg35,00€2mg46,00€5mg66,00€10mg93,00€25mg137,00€50mg210,00€100mg314,00€1mL*10mM (DMSO)72,00€Benzolamide
CAS:Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.Formula:C8H8N4O4S3Purezza:99.31%Colore e forma:SolidPeso molecolare:320.37Ref: TM-T23782
5mg51,00€10mg88,00€25mg160,00€50mg235,00€100mg349,00€200mg515,00€1mL*10mM (DMSO)57,00€4-(benzyloxy)benzene-1-sulfonamide
CAS:4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.Formula:C13H13NO3SPurezza:97.54%Colore e forma:SolidPeso molecolare:263.31EMAC10101d
CAS:<p>compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an</p>Formula:C17H15Cl2N3O2S2Purezza:99.96%Colore e forma:SolidPeso molecolare:428.36WES-1
CAS:WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,Formula:C20H20N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:396.46AHR-15010
CAS:AHR-15010 is a novel anti-arthritic agent.Formula:C10H16N2O8S2Purezza:98%Colore e forma:SolidPeso molecolare:356.37hCAIX-IN-11
CAS:hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.Formula:C21H15ClN4O3Colore e forma:SolidPeso molecolare:406.82hCAXII-IN-4
CAS:hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.Formula:C22H27N5O6SColore e forma:SolidPeso molecolare:489.54Methazolamide-d6
CAS:Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.Formula:C5H2D6N4O3S2Colore e forma:SolidPeso molecolare:242.31L 662583
CAS:L 662583 is a topical inhibitor of carbonic anhydrase.Formula:C13H17ClN2O5S3Purezza:98%Colore e forma:SolidPeso molecolare:412.93hCAI/II-IN-1
CAS:hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).Formula:C18H29N5O3S3Colore e forma:SolidPeso molecolare:459.65hCAI/II-IN-2
CAS:hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.Formula:C12H12N4O5S2Colore e forma:SolidPeso molecolare:356.38hCA IX-IN-2
hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferativeFormula:C23H24N2O4STeColore e forma:SolidPeso molecolare:552.11hCAIX-IN-14
CAS:hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .Formula:C11H17ClN6O2SColore e forma:SolidPeso molecolare:332.81hCAI/II-IN-3
CAS:"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."Formula:C16H18N4O4S2Colore e forma:SolidPeso molecolare:394.47hCAIX-IN-3
CAS:hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.Formula:C21H21BrN6O4SColore e forma:SolidPeso molecolare:533.4hCAIX/XII-IN-6
hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.Formula:C26H23N3O6S4Colore e forma:SolidPeso molecolare:601.74L-693612 HCl
CAS:L-693612 HCl is an inhibitor of carbonic anhydrase.Formula:C14H25ClN2O5S3Purezza:98%Colore e forma:SolidPeso molecolare:433.01hCAIX/XII-IN-2
CAS:Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).Formula:C19H14N2O4Colore e forma:SolidPeso molecolare:334.33CDK2-IN-12
CAS:CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Formula:C20H17N9O2SColore e forma:SolidPeso molecolare:447.47Clofenamide
CAS:Clofenamide is a low-ceiling sulfonamide diuretic.Formula:C6H7ClN2O4S2Colore e forma:SolidPeso molecolare:270.71hCAII-IN-1
CAS:hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.Formula:C21H21BrN6O4SColore e forma:SolidPeso molecolare:533.4hCAII-IN-2
CAS:hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.Formula:C25H18ClN5O4SColore e forma:SolidPeso molecolare:519.96hCAIX/XII-IN-3
CAS:Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.Formula:C20H13F3N2O4Colore e forma:SolidPeso molecolare:402.32Carbonic anhydrase inhibitor 13
CAS:Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).Formula:C17H15N5O3S2Colore e forma:SolidPeso molecolare:401.46hCAIX-IN-8
CAS:hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.Formula:C19H16N4O6Colore e forma:SolidPeso molecolare:396.35CDK2-IN-11
CAS:CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.Formula:C18H14ClN7O2SColore e forma:SolidPeso molecolare:427.87hCAXII-IN-2
CAS:hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.Formula:C21H18ClN3O4Colore e forma:SolidPeso molecolare:411.84hCA I-IN-2
CAS:hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).Formula:C26H20BrN5O3SColore e forma:SolidPeso molecolare:562.44hCA I-IN-1
CAS:hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).Formula:C27H23N5O4SColore e forma:SolidPeso molecolare:513.57hCAXII-IN-3
CAS:hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).Formula:C26H20BrN5O3SColore e forma:SolidPeso molecolare:562.44FC11409B
CAS:FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.Formula:C29H23BF4N2O3SColore e forma:SolidPeso molecolare:566.38L-693612
CAS:L-693612 is an inhibitor of carbonic anhydrase.Formula:C14H24N2O5S3Purezza:98%Colore e forma:SolidPeso molecolare:396.55Carbonic anhydrase inhibitor 7
CAS:Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.Formula:C23H17N3O5SColore e forma:SolidPeso molecolare:447.46hCAXII-IN-1
CAS:hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.Formula:C20H17NO5Colore e forma:SolidPeso molecolare:351.35hCAI/II-IN-4
CAS:hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.Formula:C15H15N3O5S2Colore e forma:SolidPeso molecolare:381.43hCAIX-IN-5
CAS:hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.Formula:C18H12FNO3Purezza:99.25%Colore e forma:SolidPeso molecolare:309.29Quinethazone
CAS:Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.Formula:C10H12ClN3O3SColore e forma:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Peso molecolare:289.74hCAIX-IN-10
CAS:"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."Formula:C28H21N3O3SColore e forma:SolidPeso molecolare:479.55Disulfamide
CAS:Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.Formula:C7H9ClN2O4S2Purezza:98.65%Colore e forma:SolidPeso molecolare:284.74hCAIX-IN-7
CAS:hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).Formula:C18H12FNO3Colore e forma:SolidPeso molecolare:309.29Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Formula:C18H17N7O2SColore e forma:SolidPeso molecolare:395.44hCAXII-IN-5
CAS:hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.Formula:C23H22N2O4Colore e forma:SolidPeso molecolare:390.43hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Formula:C18H12N2O4SColore e forma:SolidPeso molecolare:352.36DTP348
CAS:DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.Formula:C6H11N5O4SColore e forma:SolidPeso molecolare:249.25Carbonic anhydrase inhibitor 11
CAS:Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.Formula:C19H15F3N4O3S2Colore e forma:SolidPeso molecolare:468.47hCAIX/XII-IN-4
CAS:hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).Formula:C20H16N2O5Colore e forma:SolidPeso molecolare:364.35HCAIX-IN-2
CAS:HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).Formula:C19H16N8O4SColore e forma:SolidPeso molecolare:452.45GV2-20
CAS:GV2-20 is an effective carbonic anhydrase 2 inhibitors.Formula:C15H13N3O6Purezza:98%Colore e forma:SolidPeso molecolare:331.28L 645151
CAS:L 645151 is an inhibitor of lipophilic CA.Formula:C12H14N2O4S2Colore e forma:SolidPeso molecolare:314.38hCAII-IN-9
CAS:<p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>Formula:C15H16ClN3O5S2Purezza:98.63%Colore e forma:SolidPeso molecolare:417.89hCAI/II-IN-6
CAS:hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).Formula:C19H24N4O3SPurezza:98.49%Colore e forma:SolidPeso molecolare:388.48Sultiame
CAS:Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.Formula:C10H14N2O4S2Purezza:99.91%Colore e forma:SolidPeso molecolare:290.36Carbonic anhydrase inhibitor 6
CAS:Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.Formula:C26H25N3O5SPurezza:98.81%Colore e forma:SolidPeso molecolare:491.56Ref: TM-T63305
1mg167,00€2mg246,00€5mg411,00€10mg562,00€25mg867,00€50mg1.121,00€100mg1.425,00€200mg1.882,00€Carbonic anhydrase inhibitor 12
CAS:CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.Formula:C27H22BrN5O5S2Purezza:98%Colore e forma:SolidPeso molecolare:640.53hCAIX-IN-16
CAS:hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Formula:C20H20N8O2SPurezza:98%Colore e forma:SolidPeso molecolare:436.49COX-2-IN-30
CAS:COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Formula:C17H16N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:384.41CAXII-IN-1
CAS:CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.Formula:C13H7Cl2NO3SColore e forma:SolidPeso molecolare:328.17Sezolamide hydrochloride
CAS:Sezolamide hydrochloride is a potent topical carbonic anhydrase inhibitor.Formula:C11H19ClN2O4S3Colore e forma:SolidPeso molecolare:374.93hCAIX-IN-15
CAS:hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormula:C18H14FN7O2SPurezza:98%Colore e forma:SolidPeso molecolare:411.41hCAIX/XII-IN-8
CAS:hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Formula:C16H13Cl2N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:426.28N-Desethyl Brinzolamide oxalate
CAS:N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].Formula:C12H19N3O9S3Colore e forma:SolidPeso molecolare:445.49ALP/Carbonic anhydrase-IN-1
CAS:Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkalineFormula:C15H16N2Purezza:98%Colore e forma:SolidPeso molecolare:224.3Sezolamide
CAS:Sezolamide is a carbonic anhydrase inhibitor.Formula:C11H18N2O4S3Colore e forma:SolidPeso molecolare:338.47hCA XII/II/IX-IN-1
hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.Formula:C25H34N4O7SColore e forma:SolidPeso molecolare:534.63Carbonic anhydrase inhibitor 10
CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.Formula:C14H17N5O3SColore e forma:SolidPeso molecolare:335.38β-Glucuronidase/hCAII-IN-1
CAS:β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50Formula:C30H21NO9Colore e forma:SolidPeso molecolare:539.49NSC 828467
NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).Formula:C21H19N9O2SColore e forma:SolidPeso molecolare:461.5hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].Formula:C9H13N3O4SColore e forma:SolidPeso molecolare:259.28CAII-IN-2
CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.Formula:C18H19BrN4SColore e forma:SolidPeso molecolare:403.34Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Formula:C24H20ClN3O3SColore e forma:SolidPeso molecolare:465.95Carbonic anhydrase inhibitor 9
Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.Formula:C22H20BrN5O4SColore e forma:SolidPeso molecolare:530.39hCAII-IN-5
CAS:hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Formula:C29H18N2O7Colore e forma:SolidPeso molecolare:506.46hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formula:C17H21N3O3SColore e forma:SolidPeso molecolare:347.43Perfluorohexane sulfonamide
CAS:Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.Formula:C6H2F13NO2SColore e forma:SolidPeso molecolare:399.13AChE/CA I-IN-1
AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.Formula:C14H19NO6SColore e forma:SolidPeso molecolare:329.37hCAIX/XII-IN-15
CAS:hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.Formula:C17H18O4SColore e forma:SolidPeso molecolare:318.387Carbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.Formula:C21H18N2O4SColore e forma:SolidPeso molecolare:394.44CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.Formula:C16H22N4O8SColore e forma:SolidPeso molecolare:430.43Carbonic anhydrase inhibitor 16
CAS:Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.Formula:C14H10N2O4SPurezza:99.65%Colore e forma:SolidPeso molecolare:302.31CA IX-IN-3
CAS:CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.Formula:C21H19N5O4S2Colore e forma:SolidPeso molecolare:469.537CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Formula:C19H21FN4SColore e forma:SolidPeso molecolare:356.46hCAVII/IX-IN-1
CAS:hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.Formula:C7H7N3O2S2Colore e forma:SolidPeso molecolare:229.279CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Formula:C18H18F2N4SColore e forma:SolidPeso molecolare:360.42β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Colore e forma:SolidPeso molecolare:537.52Carbonic anhydrase inhibitor 2
CAS:Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.Formula:C12H16N4O6SColore e forma:SolidPeso molecolare:344.34hCAII-IN-4
CAS:hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.Formula:C31H23NO9Colore e forma:SolidPeso molecolare:553.52Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Formula:C15H17N3O3SColore e forma:SolidPeso molecolare:319.38Valerate sodium
CAS:<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formula:C5H9NaO2Purezza:99.84%Colore e forma:SolidPeso molecolare:124.11hCAI/II/XII-IN-1
CAS:<p>hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.</p>Formula:C12H12N2O2SColore e forma:SolidPeso molecolare:248.301hCAIX-IN-20
CAS:hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with a Ki of 2.7 nM, playing a significant role in cancer research.Formula:C19H13Cl2N5O4S2Peso molecolare:510.37Carbonic anhydrase inhibitor 17
CAS:Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.Formula:C18H15ClN4O3S2Peso molecolare:434.92Carbonic anhydrase inhibitor 19
CAS:Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.Formula:C23H25N3O6S2Peso molecolare:503.59α-Glucosidase-IN-63
CAS:α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]Formula:C16H12FN3O3S2Colore e forma:SolidPeso molecolare:377.41EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Formula:C24H15FO3Colore e forma:SolidPeso molecolare:370.37Sulclamide
CAS:Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].Formula:C7H7ClN2O3SColore e forma:SolidPeso molecolare:234.664-Acetylphenylboronic acid
CAS:4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).Formula:C8H9BO3Colore e forma:SolidPeso molecolare:163.97O-Desmethyl Brinzolamide hydrochloride
CAS:O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Formula:C11H20ClN3O5S3Colore e forma:SolidPeso molecolare:405.94Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5
