PPAR
I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.
Trovati 164 prodotti di "PPAR"
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Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Formula:C22H28ClNO5Purezza:98.82%Colore e forma:SolidPeso molecolare:421.91Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purezza:95.1% - 99.79%Colore e forma:Needles From Acetone/Light Petroleum SolidPeso molecolare:596.84SR 16832
CAS:<p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>Formula:C17H12ClN3O4Purezza:99.6%Colore e forma:SolidPeso molecolare:357.75BMS-687453
CAS:<p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>Formula:C22H21ClN2O6Purezza:99.4%Colore e forma:SolidPeso molecolare:444.86NSC-87877 disodium
CAS:<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Formula:C19H13N3O7S2·2NaPurezza:97.89%Colore e forma:SolidPeso molecolare:503.42Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purezza:99.76%Colore e forma:SolidPeso molecolare:254.41Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purezza:97.02% - 99.94%Colore e forma:White PowderPeso molecolare:434.35GW6471
CAS:<p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>Formula:C35H36F3N3O4Purezza:98.23% - 99.55%Colore e forma:SolidPeso molecolare:619.67Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Formula:C33H40O15Purezza:97.82% - 98.3%Colore e forma:SolidPeso molecolare:676.66Glabrone
CAS:<p>Glabrone shows antiviral activity against influenza virus.</p>Formula:C20H16O5Purezza:99.08% - 99.55%Colore e forma:SolidPeso molecolare:336.34FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Formula:C13H10Cl2N2O4SPurezza:98.25% - 99.5%Colore e forma:SolidPeso molecolare:361.2OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Formula:C44H70O16Purezza:99.46% - ≥95%Colore e forma:SolidPeso molecolare:855.02SR1664
CAS:<p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>Formula:C33H29N3O5Purezza:98.02%Colore e forma:SolidPeso molecolare:547.6GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formula:C13H9ClN2O3Purezza:98% - 99.95%Colore e forma:Off-White SolidPeso molecolare:276.68LJ570
CAS:<p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>Formula:C27H22O3Purezza:99.64%Colore e forma:SolidPeso molecolare:394.46Angeloylgomisin H
CAS:<p>Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.</p>Formula:C28H36O8Purezza:99.84% - 99.95%Colore e forma:SolidPeso molecolare:500.58GW 501516
CAS:<p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>Formula:C21H18F3NO3S2Purezza:98.91% - 99.64%Colore e forma:White SolidPeso molecolare:453.50NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Formula:C21H23NO4Purezza:99.93% - 99.94%Colore e forma:White Crystalline PowderPeso molecolare:353.41Seladelpar
CAS:<p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>Formula:C21H23F3O5SPurezza:99.18% - 99.41%Colore e forma:SolidPeso molecolare:444.46Ciprofibrate
CAS:<p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>Formula:C13H14Cl2O3Purezza:99.63% - >99.99%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:289.15
