PPAR
I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.
Trovati 164 prodotti di "PPAR"
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GW590735
CAS:<p>GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.</p>Formula:C23H21F3N2O4SPurezza:99.53%Colore e forma:SolidPeso molecolare:478.48PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Formula:C23H28FN7O3Colore e forma:SolidPeso molecolare:469.51GQ-16
CAS:<p>GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.</p>Formula:C19H16BrNO3SPurezza:99.84%Colore e forma:SolidPeso molecolare:418.3CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Formula:C26H33NO5Purezza:99.84%Colore e forma:SolidPeso molecolare:439.54PPAR α/PPARA Protein, Human, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.</p>Colore e forma:Lyophilized PowderPeso molecolare:31.36 kDa (predicted)PPAR α/PPARA Protein, Mouse, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.</p>Colore e forma:Lyophilized PowderPeso molecolare:31.49 kDa (predicted)Balaglitazone
CAS:<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Formula:C20H17N3O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:395.43Ciprofibrate
CAS:<p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>Formula:C13H14Cl2O3Purezza:99.63% - >99.99%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:289.15Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purezza:97.02% - 99.94%Colore e forma:White PowderPeso molecolare:434.35MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formula:C27H34ClNO2SPurezza:99.23% - 99.84%Colore e forma:SolidPeso molecolare:472.08LJ570
CAS:<p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>Formula:C27H22O3Purezza:99.64%Colore e forma:SolidPeso molecolare:394.46Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Formula:C22H28ClNO5Purezza:98.82%Colore e forma:SolidPeso molecolare:421.91Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formula:C18H19N3O3SPurezza:98.61% - 99.87%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:357.43NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Formula:C21H23NO4Purezza:99.93% - 99.94%Colore e forma:White Crystalline PowderPeso molecolare:353.41Seladelpar
CAS:<p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>Formula:C21H23F3O5SPurezza:99.18% - 99.41%Colore e forma:SolidPeso molecolare:444.46Norathyriol
CAS:<p>Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.</p>Formula:C13H8O6Purezza:99.35% - 99.55%Colore e forma:SolidPeso molecolare:260.2Pirinixic Acid
CAS:<p>Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.</p>Formula:C14H14ClN3O2SPurezza:98.27% - 99.92%Colore e forma:SolidPeso molecolare:323.8Bilobetin
CAS:<p>Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.</p>Formula:C31H20O10Purezza:97.74% - 99.69%Colore e forma:SolidPeso molecolare:552.48GW 501516
CAS:<p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>Formula:C21H18F3NO3S2Purezza:98.91% - 99.64%Colore e forma:White SolidPeso molecolare:453.50OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Formula:C44H70O16Purezza:99.46% - ≥95%Colore e forma:SolidPeso molecolare:855.02BMS-687453
CAS:<p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>Formula:C22H21ClN2O6Purezza:99.4%Colore e forma:SolidPeso molecolare:444.86Licarin B
CAS:<p>1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.</p>Formula:C20H20O4Purezza:99.82% - ≥95%Colore e forma:SolidPeso molecolare:324.37Eupatilin
CAS:<p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>Formula:C18H16O7Purezza:98.53% - 99%Colore e forma:SolidPeso molecolare:344.32GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formula:C13H9ClN2O3Purezza:98% - 99.95%Colore e forma:Off-White SolidPeso molecolare:276.68SR1664
CAS:<p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>Formula:C33H29N3O5Purezza:98.02%Colore e forma:SolidPeso molecolare:547.6FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Formula:C13H10Cl2N2O4SPurezza:98.25% - 99.5%Colore e forma:SolidPeso molecolare:361.2Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Formula:C33H40O15Purezza:97.82% - 98.3%Colore e forma:SolidPeso molecolare:676.66Glabrone
CAS:<p>Glabrone shows antiviral activity against influenza virus.</p>Formula:C20H16O5Purezza:99.08% - 99.55%Colore e forma:SolidPeso molecolare:336.34GW6471
CAS:<p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>Formula:C35H36F3N3O4Purezza:98.23% - 99.55%Colore e forma:SolidPeso molecolare:619.67Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purezza:99.76%Colore e forma:SolidPeso molecolare:254.41NSC-87877 disodium
CAS:<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Formula:C19H13N3O7S2·2NaPurezza:97.89%Colore e forma:SolidPeso molecolare:503.42SR 16832
CAS:<p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>Formula:C17H12ClN3O4Purezza:99.6%Colore e forma:SolidPeso molecolare:357.75GW0742
CAS:<p>GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).</p>Formula:C21H17F4NO3S2Purezza:99.75% - 99.85%Colore e forma:SolidPeso molecolare:471.49CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Formula:C34H43N3O3Purezza:98.3% - 99.61%Colore e forma:SolidPeso molecolare:541.72SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Formula:C16H11ClF3N3O2SPurezza:99.74%Colore e forma:SolidPeso molecolare:401.79Raspberry ketone
CAS:<p>1.</p>Formula:C10H12O2Purezza:99.84% - 99.89%Colore e forma:White Solid CrystallinePeso molecolare:164.2Fisetin
CAS:<p>Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.</p>Formula:C15H10O6Purezza:94.14% - 99.05%Colore e forma:Yellow To Brown Crystalline PowderPeso molecolare:286.24Ginsenoside Rh1
CAS:<p>Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.</p>Formula:C36H62O9Purezza:99% - 99.77%Colore e forma:SolidPeso molecolare:638.87Alpinetin
CAS:<p>Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.</p>Formula:C16H14O4Purezza:98.39%Colore e forma:SolidPeso molecolare:270.28Glabridin
CAS:<p>Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.</p>Formula:C20H20O4Purezza:99.78% - 99.99%Colore e forma:Light Yellow Powder Insoluble In WaterPeso molecolare:324.37Convallatoxin
CAS:<p>Convallatoxin is a natural product.</p>Formula:C29H42O10Purezza:99.27% - 99.53%Colore e forma:Prisms From Methanol + Ether SolidPeso molecolare:550.64Methyl oleanonate
CAS:<p>3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.</p>Formula:C31H48O3Purezza:98.99%Colore e forma:SolidPeso molecolare:468.71Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purezza:95.1% - 99.79%Colore e forma:Needles From Acetone/Light Petroleum SolidPeso molecolare:596.84Agrimol B
CAS:<p>1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.</p>Formula:C37H46O12Purezza:99.06% - ≥95%Colore e forma:SolidPeso molecolare:682.75(E/Z)-Elafibranor
CAS:<p>GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.</p>Formula:C22H24O4SPurezza:98.36%Colore e forma:SolidPeso molecolare:384.49Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Formula:C13H26N2O4Purezza:99.35% - 99.73%Colore e forma:SolidPeso molecolare:274.36GW1929
CAS:<p>GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).</p>Formula:C30H29N3O4Purezza:98.1% - 98.21%Colore e forma:SolidPeso molecolare:495.57Bocidelpar
CAS:<p>Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.</p>Formula:C25H27F3N2O3Purezza:97.77%Colore e forma:SolidPeso molecolare:460.49Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Formula:C24H27NO5SPurezza:98% - 99.8%Colore e forma:Yellow SolidPeso molecolare:441.54Tetradecylthioacetic acid
CAS:<p>Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.</p>Formula:C16H32O2SPurezza:99.93%Colore e forma:SolidPeso molecolare:288.49
