Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(647 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.027 prodotti)
- BACE(37 prodotti)
- Beta amiloide(230 prodotti)
- CaMK(73 prodotti)
- COX(602 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(373 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5639 prodotti di "Neuroscienza"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
CVN417
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.Colore e forma:Odour SolidRivanicline 2HCl
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.Formula:C10H16Cl2N2Purezza:99.4%Colore e forma:SoildPeso molecolare:235.15Ref: TM-T12738L1
1mg34,00€5mg71,00€10mg100,00€1mL*10mM (DMSO)110,00€25mg234,00€50mg420,00€100mg617,00€Ro60-0175
CAS:Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.Formula:C11H12ClFN2Purezza:97.09%Colore e forma:SolidPeso molecolare:226.68Ref: TM-T39161
1mg93,00€1mL*10mM (DMSO)187,00€5mg205,00€10mg334,00€25mg587,00€50mg802,00€100mg1.108,00€4,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10F2OColore e forma:Off-White CrystalsPeso molecolare:220.21GABOB (β-hydroxy-GABA)
CAS:GABOB, an epilepsy treatment, is GABA's analogue and may act as a neurotransmitter.Formula:C4H9NO3Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:119.12(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purezza:99.18%Colore e forma:SolidPeso molecolare:222.63Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColore e forma:SolidPeso molecolare:238.31LY 344864 racemate
CAS:LY 344864 racemate is a 5-HT1F receptor agonist.Formula:C21H22FN3OPurezza:99.75%Colore e forma:SoildPeso molecolare:351.42Ref: TM-T2344L
100mgPrezzo su richiesta1mL*10mM (DMSO)34,00€5mg43,00€10mg66,00€25mg100,00€50mg166,00€SD-254
CAS:SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.Formula:C17H27NO2Peso molecolare:286.46Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formula:C22H16F3N3O3SColore e forma:SolidPeso molecolare:459.44M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurezza:99.14%Colore e forma:SolidPeso molecolare:290.38ALEPH hydrochloride
CAS:ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Formula:C12H20ClNO2SColore e forma:SolidPeso molecolare:277.81AChE/BuChE/MAO-B-IN-2
AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,Formula:C19H18FNO3Colore e forma:SolidPeso molecolare:327.35Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purezza:99.76%Colore e forma:SolidPeso molecolare:468.37CAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Formula:C27H42OColore e forma:SolidPeso molecolare:382.632Donitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormula:C23H26ClN5O2Purezza:99.8% - 99.86%Colore e forma:SolidPeso molecolare:439.94Ref: TM-T21666
500mgPrezzo su richiesta2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.Formula:C19H13BrFN3O2Purezza:98%Colore e forma:SolidPeso molecolare:414.23Neocarzinostatin
CAS:Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Purezza:98%Colore e forma:SolidPeso molecolare:N/AhAChE-IN-4
Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study ofFormula:C30H23Cl3N2O3Colore e forma:SolidPeso molecolare:565.875-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formula:C15H20N2OColore e forma:SolidPeso molecolare:244.33Velnacrine
CAS:Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.Formula:C13H14N2OPurezza:99.83%Colore e forma:SolidPeso molecolare:214.26Stacofylline
CAS:Stacofylline is a xanthine derivative that is used to treat migraine headaches.Formula:C20H33N7O3Purezza:99.43% - 99.85%Colore e forma:SolidPeso molecolare:419.52DDC 2′,3′-O-disulfate
DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].Formula:C17H16O11S2Colore e forma:SolidPeso molecolare:460.43Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formula:C18H23N6O14P3SColore e forma:SolidPeso molecolare:672.39MPPG
CAS:MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).Formula:C9H12NO5PColore e forma:SolidPeso molecolare:245.171HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Colore e forma:Odour SolidOsmanthuside B
CAS:Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.Formula:C29H36O13Colore e forma:SolidPeso molecolare:592.59AZD4694 Precursor
CAS:AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.Formula:C22H25N3O7Colore e forma:SolidPeso molecolare:443.45Bleformin A
CAS:Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.Formula:C23H20O5Colore e forma:SolidPeso molecolare:376.4Bensultap
CAS:Bensultap is an agricultural chemical typically used as a pesticide.Formula:C17H21NO4S4Purezza:98%Colore e forma:SolidPeso molecolare:431.61RAGE antagonist peptide
CAS:RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.Formula:C57H101N13O17SPurezza:98%Colore e forma:SolidPeso molecolare:1272.56AChE-IN-34
AChE-IN-34 (compound 5l) is a potent, selective AChE inhibitor exhibiting an IC50 of 3.98 µM and negligible BChE inhibition.Formula:C19H14N8O6Colore e forma:SolidPeso molecolare:450.36Oxatomide
CAS:Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Formula:C27H30N4OPurezza:99.28% - 99.72%Colore e forma:White PowderPeso molecolare:426.55Ref: TM-T19839
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg222,00€50mg356,00€100mg557,00€500mg1.153,00€AChE-IN-39
AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential toFormula:C19H15NO3Colore e forma:SolidPeso molecolare:305.33FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormula:C15H13FN2OPurezza:98%Colore e forma:SolidPeso molecolare:256.27Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Colore e forma:Odour SolidMMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:369.8Ref: TM-T23008L
1mg56,00€5mg119,00€1mL*10mM (DMSO)133,00€10mg192,00€25mg394,00€50mg585,00€100mg833,00€200mg1.134,00€12,14-Dichlorodehydroabietic acid
CAS:12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Formula:C20H26Cl2O2Colore e forma:SolidPeso molecolare:369.33Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formula:C12H4Cl2F6N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:453.14pCPA methyl ester hydrochloride
CAS:pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.
Formula:C10H13Cl2NO2Purezza:99.73% - 99.88%Colore e forma:SolidPeso molecolare:250.12AChE-IN-46
AChE-IN-46 (compound 4), a β-cyclocostunolide, functions as an acetylcholinesterase (AChE) inhibitor [1].Formula:C15H22O2Colore e forma:SolidPeso molecolare:234.33NPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.Formula:C25H26ClN3O2SPurezza:99.84%Colore e forma:SoildPeso molecolare:468.01Ref: TM-T12262L1
1mg38,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg113,00€25mg188,00€50mg273,00€100mg371,00€200mg494,00€Exosome Compound Library
76 exosome-related compounds that can be used for high-throughput and high-content screening.
Colore e forma:Odour SolidChrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.545BChE-IN-39
BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.Formula:C29H23ClFN3O3Colore e forma:SolidPeso molecolare:515.963Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Colore e forma:SolidPeso molecolare:237.295Arisugacin G
CAS:Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).Formula:C27H32O5Colore e forma:SolidPeso molecolare:436.54PF-03382792
CAS:PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Formula:C23H32FN3O4Purezza:99.64%Colore e forma:SolidPeso molecolare:433.52GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Colore e forma:SolidPeso molecolare:504.59β-Amyloid (1-43)(human) TFA
β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.Formula:C209H319F3N56O64SColore e forma:SolidPeso molecolare:4729.21Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7300
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaBChE-IN-35
BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).Formula:C35H39N5O2Colore e forma:SolidPeso molecolare:561.72Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Formula:C70H123N20F3O20Colore e forma:SolidPeso molecolare:1621.84MAO-B-IN-36
MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.Formula:C20H14O3Colore e forma:SolidPeso molecolare:302.32Histamine & Melatonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS
Colore e forma:Odour SolidZanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Formula:C25H32N2OColore e forma:SolidPeso molecolare:376.544(Gln22)-Amyloid β-Protein (1-42)
CAS:(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].Formula:C203H312N56O59SColore e forma:SolidPeso molecolare:4513.05Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.Formula:C128H216F3N45O36SColore e forma:SolidPeso molecolare:3050.42Fezolamine
CAS:Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Formula:C20H23N3Purezza:99.86%Colore e forma:SolidPeso molecolare:305.42Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Colore e forma:Odour SolidSerotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;Colore e forma:Odour SolidRef: TM-L2800
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaIon Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Colore e forma:Odour SolidCalcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7200
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaβ-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purezza:98%Colore e forma:SolidPeso molecolare:3262.51sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColore e forma:SolidPeso molecolare:193.25CNS-Penetrant Compound Library
A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);Colore e forma:Odour SolidRef: TM-L5900
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestamGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Colore e forma:SolidPeso molecolare:363.82Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Formula:C10H13Li4N6O13P3Colore e forma:SolidPeso molecolare:545.93γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48Neural Regeneration Compound Library
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7700
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaMinesapride
CAS:Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formula:C21H31ClN4O5Purezza:99.85% - 99.88%Colore e forma:SolidPeso molecolare:454.95OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).Formula:C81H126F3N23O24Colore e forma:SolidPeso molecolare:1863Apoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;Colore e forma:Odour SolidRef: TM-L9000
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiesta(+)-OSU 6162
CAS:(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formula:C15H23NO2SPurezza:98.19%Colore e forma:SoildPeso molecolare:281.41Ref: TM-T60027
1mg73,00€5mg146,00€1mL*10mM (DMSO)155,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€Guluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formula:C6H10O7Purezza:98%Colore e forma:SolidPeso molecolare:194.139MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Formula:C91H156N36O20Colore e forma:SolidPeso molecolare:2074.44Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurezza:99.63% - 99.96%Colore e forma:SolidPeso molecolare:390.4Ref: TM-T9694
1mg120,00€2mg170,00€5mg289,00€1mL*10mM (DMSO)319,00€10mg467,00€25mg835,00€50mg1.134,00€100mg1.504,00€Acetyl-Tau Peptide (273-284) amide
CAS:Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.Formula:C64H116N18O17Colore e forma:SolidPeso molecolare:1409.72(Glu20)-Amyloid β-Protein (1-42)
CAS:(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.Formula:C199H309N55O62SColore e forma:SolidPeso molecolare:4495.981H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formula:C10H12N2O2SPurezza:99.96%Colore e forma:SoildPeso molecolare:224.28Aducanumab
CAS:Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.Purezza:95% - 97.10%Colore e forma:LiquidPeso molecolare:145.93 kDa3-Aminopropylphosphonic Acid
CAS:3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formula:C3H10NO3PPurezza:99.84%Colore e forma:Light Yellow LiquidPeso molecolare:139.09Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Colore e forma:Odour LiquidOM99-2 TFA
CAS:OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.Formula:C43H65F3N8O16Colore e forma:SolidPeso molecolare:1007.028Neuronal Signaling Compound Library
A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;Colore e forma:Odour SolidRef: TM-L2600
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaAmyloid β-Protein (3-42)
CAS:Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified toColore e forma:SolidCevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Formula:C20H38Cl2N2O3S2Purezza:97.00%Colore e forma:SolidPeso molecolare:489.55Ref: TM-T2390
25mgPrezzo su richiesta50mgPrezzo su richiesta2mg43,00€5mg64,00€1mL*10mM (DMSO)70,00€10mg89,00€MAO-B-IN-20
MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.Formula:C20H18F2N2O2Colore e forma:SolidPeso molecolare:356.37LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Formula:C25H31F2NO11SColore e forma:SolidPeso molecolare:591.58Syk Inhibitor II hydrochloride
CAS:Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.Formula:C14H16ClF3N6OPurezza:99.05%Colore e forma:SolidPeso molecolare:376.77LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Formula:C25H32ClF2NO11SColore e forma:SolidPeso molecolare:628.03BuChE-IN-13
BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.
Colore e forma:Odour Solid(Met(O)35)-Amyloid β-Protein (1-42)
(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that ofFormula:C203H311N55O61SColore e forma:SolidPeso molecolare:4530.04Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Colore e forma:SolidPeso molecolare:160.22AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Formula:C42H32FN3O7Purezza:98%Colore e forma:SolidPeso molecolare:709.72RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFormula:C42H39F6N5O2P2RuPurezza:98%Colore e forma:SolidPeso molecolare:922.8LP 12 hydrochloride
CAS:LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).Formula:C32H40ClN3OColore e forma:SolidPeso molecolare:518.14Heliosupine
Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.Formula:C20H31NO7Colore e forma:SolidPeso molecolare:397.468(S)-Vamicamide
CAS:(S)-Vamicamide is an anti-anticholinergic compound.Formula:C18H23N3OPurezza:99.48% - 99.65%Colore e forma:SoildPeso molecolare:297.39mcK6A1
mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.Formula:C71H99N17O16Colore e forma:SolidPeso molecolare:1446.65OM99-2
CAS:OM99-2, an 8-residue peptidomimetic, binds memapsin 2 with 9.58 nM Ki; promising for Alzheimer's research.Formula:C41H64N8O14Colore e forma:SolidPeso molecolare:893.005Dehydrodiscretamine chloride
CAS:Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,Formula:C19H18ClNO4Colore e forma:SolidPeso molecolare:359.8Biotin-β-Amyloid (1-42), human TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in theFormula:C215H326F3N57O64S2Colore e forma:SolidPeso molecolare:4854.36AChE/Aβ-IN-6
BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.Colore e forma:Odour Solid(Rac)-Norcisapride
CAS:Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.Formula:C14H20ClN3O3Purezza:99.32%Colore e forma:SoildPeso molecolare:313.78Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Formula:C21H32BrNO2Colore e forma:SolidPeso molecolare:410.39CPN-267 TFA
CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.Formula:C54H68F6N16O12SColore e forma:SolidPeso molecolare:1279.27AChE/BuChE-IN-6
AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.Formula:C24H20ClN3O3Colore e forma:SolidPeso molecolare:433.887β-Amyloid (1-38), mouse, rat
CAS:β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.Colore e forma:Solid(Met(O2)35)-Amyloid β-Protein (1-42)
(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .Formula:C203H311N55O62SColore e forma:SolidPeso molecolare:4546.04hAChE/hBuChE-IN-1
hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.Formula:C30H31FN2O3Colore e forma:SolidPeso molecolare:486.577β-Amyloid (29-40)
CAS:β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFormula:C49H88N12O13SPurezza:98%Colore e forma:SolidPeso molecolare:1085.36FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Formula:C227H330N58O66S2Colore e forma:SolidPeso molecolare:4991.53(D-Asp1)-Amyloid β-Protein (1-42)
CAS:(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid depositsFormula:C203H311N55O60SColore e forma:SolidPeso molecolare:4514.04CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formula:C70H105F3N14O15SColore e forma:SolidPeso molecolare:1471.72Femoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formula:C20H25NO2Purezza:99.1% - 99.35%Colore e forma:SolidPeso molecolare:311.42α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFormula:C83H125N27O27S5Purezza:98%Colore e forma:SolidPeso molecolare:2093.37Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Formula:C23H24ClNO8Colore e forma:SolidPeso molecolare:477.89Pseudocoptisine acetate
CAS:Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.Formula:C21H17NO6Purezza:98%Colore e forma:SolidPeso molecolare:379.36Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C36H60O8Colore e forma:SolidPeso molecolare:620.868AChE-IN-37
AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.Formula:C21H12ClNO7SColore e forma:SolidPeso molecolare:457.84(Rac)-Sabcomeline
CAS:(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.Formula:C10H15N3OPurezza:99.14%Colore e forma:SolidPeso molecolare:193.25Ref: TM-T68135L1
1mg109,00€2mg160,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Formula:C14H15BrN2OSColore e forma:SolidPeso molecolare:339.25KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Formula:C22H12F3N5Na2O7Purezza:97.27%Colore e forma:SoildPeso molecolare:561.33Orexin B, human
CAS:Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.Formula:C123H212N44O35SPurezza:98%Colore e forma:SolidPeso molecolare:2899.34mGluR3 modulator-1
CAS:1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.Formula:C16H21N3OPurezza:98.99%Colore e forma:SolidPeso molecolare:271.36Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Formula:C152H243N47O44S4Purezza:98%Colore e forma:SolidPeso molecolare:3561.1PD24
PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for humanFormula:C24H22N2O6Colore e forma:SolidPeso molecolare:434.44Naratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Formula:C17H26ClN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:374.94DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Formula:C23H22FNO4Purezza:99.54%Colore e forma:SolidPeso molecolare:395.42G923-0271
CAS:G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.Formula:C28H23FN4OColore e forma:SolidPeso molecolare:450.51GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Colore e forma:SolidPeso molecolare:332.79Imipramine N-oxide
CAS:Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.Formula:C19H24N2OPurezza:99.80%Colore e forma:SolidPeso molecolare:296.41Ref: TM-T74205
1mg72,00€5mg157,00€1mL*10mM (DMSO)167,00€10mg241,00€25mg409,00€50mg565,00€100mg794,00€Lisuride maleate
CAS:Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formula:C24H30N4O5Purezza:99.85%Colore e forma:SolidPeso molecolare:454.52Ref: TM-T8775
1mg204,00€5mg627,00€1mL*10mM (DMSO)627,00€10mg898,00€25mg1.346,00€50mg1.745,00€100mg2.382,00€Pyridostigmine bromide
CAS:Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Formula:C9H13BrN2O2Purezza:99.00% - 99.98%Colore e forma:White Or Practically White Crystalline Powder Pale Yellow To Colorless LiquidPeso molecolare:261.128-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purezza:99.82%Colore e forma:SolidPeso molecolare:150.14LU-32-176B
CAS:LU32-176B is a bioactive chemical.Formula:C23H24F2N2O2Colore e forma:SolidPeso molecolare:398.45Feralolide
CAS:Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) andFormula:C18H16O7Colore e forma:SolidPeso molecolare:344.32AChE-IN-36
AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].Formula:C25H21ClO5SColore e forma:SolidPeso molecolare:468.95Tabernanthalog
CAS:TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.Formula:C14H18N2OPurezza:99.82% - 99.89%Colore e forma:SoildPeso molecolare:230.31Ref: TM-T60221
1mg175,00€2mg264,00€1mL*10mM (DMSO)344,00€5mg404,00€10mg592,00€25mg888,00€50mg1.243,00€100mg1.701,00€500mg3.402,00€3-Aminopropylphosphinic acid
CAS:3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).
Formula:C3H10NO2PColore e forma:SolidPeso molecolare:123.092Cyclodrine
CAS:Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.Formula:C19H29NO3Purezza:97.62%Colore e forma:SoildPeso molecolare:319.44Ref: TM-T10914L
1mg73,00€1mL*10mM (DMSO)148,00€5mg149,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€Methyllycaconitine citrate
CAS:Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.Formula:C43H58N2O17Purezza:98.03% - 98.91%Colore e forma:SolidPeso molecolare:874.92XL01126
XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.Formula:C50H64ClFN10O6S2Colore e forma:SolidPeso molecolare:1019.69(S)-UFR2709 hydrochloride
CAS:(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.Formula:C13H18ClNO2Purezza:98.94%Colore e forma:SolidPeso molecolare:255.74α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFormula:C79H125N27O25S4Purezza:98%Colore e forma:SolidPeso molecolare:1981.3BTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Formula:C28H52N2O4Purezza:98.1%Colore e forma:SolidPeso molecolare:480.72TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Colore e forma:Odour SolidNeuroprotective Compound Library
A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);
Colore e forma:Odour SolidFRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFormula:C22H22ClN5O2Colore e forma:SolidPeso molecolare:423.9p-HTAA
CAS:Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].Formula:C24H16O4S5Colore e forma:SolidPeso molecolare:528.71Sintamil
CAS:Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.Formula:C18H20ClN3O4Colore e forma:SolidPeso molecolare:377.822-Methyl-1-indanone
CAS:2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.Formula:C10H10OPurezza:96.6%Colore e forma:SolidPeso molecolare:146.19M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Colore e forma:SolidPeso molecolare:315.45β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormula:C70H102N18O18Purezza:98%Colore e forma:SolidPeso molecolare:1483.67BuChE-IN-21
BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.Formula:C16H23NO2Colore e forma:SolidPeso molecolare:261.17288MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Colore e forma:SolidPeso molecolare:217.15Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formula:C11H21NO4Purezza:98%Colore e forma:SolidPeso molecolare:231.29Duloxetine D3 hydrochloride
CAS:Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.Formula:C18H20ClNOSPurezza:98%Colore e forma:SolidPeso molecolare:336.89Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Formula:C130H219N45O40S2Colore e forma:SolidPeso molecolare:3116.54α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purezza:98%Colore e forma:SolidPeso molecolare:1351.56UCM 549
CAS:UCM 549 is a bioactive chemical.Formula:C19H21NO2Colore e forma:SolidPeso molecolare:295.385H-Pyrido[4,3-b]indole
CAS:5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.Formula:C11H8N2Purezza:99.6%Colore e forma:SolidPeso molecolare:168.2Amyloid-Forming peptide GNNQQNY
CAS:Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental inFormula:C33H48N12O14Colore e forma:SolidPeso molecolare:836.81Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formula:C10H19NO2Colore e forma:SolidPeso molecolare:185.26Eletriptan
CAS:Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.Formula:C22H26N2O2SColore e forma:SolidPeso molecolare:382.52Sulamserod
CAS:Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormula:C19H28ClN3O5SPurezza:98.76%Colore e forma:SolidPeso molecolare:445.96RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Colore e forma:Odour SolidOXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formula:C79H125N23O22Purezza:98%Colore e forma:SolidPeso molecolare:1749Salvianolic acid H
CAS:Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].Formula:C27H22O12Colore e forma:SolidPeso molecolare:538.46AChE-IN-70
AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.Colore e forma:Odour SolidN-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purezza:99.65%Colore e forma:SolidPeso molecolare:136.19Rasagiline 13C3 mesylate racemic
CAS:Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.Formula:C13H17NO3SPurezza:98%Colore e forma:SolidPeso molecolare:270.32Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Formula:C15H11N5OColore e forma:SolidPeso molecolare:277.28α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Colore e forma:SolidPeso molecolare:397.4BuChE-IN-16
BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.Formula:C16H22N2O3Colore e forma:SolidPeso molecolare:290.362'-O-Succinyl-cAMP
CAS:2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2Formula:C14H16N5O9PColore e forma:SolidPeso molecolare:429.282SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurezza:99.79%Colore e forma:SoildPeso molecolare:237.36(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Formula:C10H11NO4Colore e forma:SolidPeso molecolare:209.201Xanthohumol I
Xanthohumol I is a natural product that can be used as a reference standard.Formula:C21H22O6Colore e forma:SolidPeso molecolare:370.401BMS-906024
CAS:BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.Formula:C26H26F6N4O3Purezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:556.5Pomaglumetad methionil anhydrous
CAS:LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.Formula:C12H18N2O7S2Purezza:98%Colore e forma:SolidPeso molecolare:366.41Notch 1 TFA
Notch 1 TFA encodes a member of the NOTCH family of proteins.Formula:C64H98N15F3O25S3Purezza:98%Colore e forma:SolidPeso molecolare:1614.81AChE/BChE-IN-15
AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (Formula:C29H30N6O3Colore e forma:SolidPeso molecolare:510.59BChE-IN-21
BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research inColore e forma:Odour Solid(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Formula:C22H32ClNO2Colore e forma:SolidPeso molecolare:377.95AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electricFormula:C18H19BrN2O2Colore e forma:SolidPeso molecolare:375.26AC3-I, myristoylated
Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).
Formula:C78H137N21O20Purezza:98%Colore e forma:SolidPeso molecolare:1689.055-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formula:C25H29ClN4O2SColore e forma:SolidPeso molecolare:485.04CUR-IPA
CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.Formula:C43H38N2O8Colore e forma:SolidPeso molecolare:710.77Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formula:C6H10BrNO2Purezza:98%Colore e forma:SolidPeso molecolare:208.05Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.Formula:C22H24N4O2Colore e forma:SolidPeso molecolare:376.45MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formula:C295H455N95O97S10Purezza:98%Colore e forma:SolidPeso molecolare:7205CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Formula:C54H58Cl2N10O11Purezza:98%Colore e forma:SolidPeso molecolare:1094GAD65(247-266) epitope TFA
GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeitFormula:C111H174F3N27O29S4Purezza:98%Colore e forma:SolidPeso molecolare:2535.99MAO-B-IN-4
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.Formula:C23H20ClF2N3Purezza:98%Colore e forma:SolidPeso molecolare:411.87MAO-IN-6
MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.Formula:C22H14F3NO2Colore e forma:SolidPeso molecolare:381.35Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificityFormula:C18H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:310.35COX-1/2-IN-5
COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and
Formula:C21H22N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:414.47BMY-14802
CAS:BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formula:C18H22F2N4OPurezza:99.84%Colore e forma:SoildPeso molecolare:348.39Ref: TM-T67739
2mg35,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg90,00€25mg164,00€50mg259,00€100mg383,00€200mg545,00€
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
![5H-Pyrido[4,3-b]indole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTN9455.webp&w=3840&q=75)
