Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1095 prodotti di "Proteasi/Proteasoma"
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Cyclophilin inhibitor 3
CAS:Cyclophilin inhibitor 3 (compound 7c), a potent inhibitor of cyclophilin A (CypA), exhibited potent anti-HCV effects with an EC50 value of 4.2 μM.Formula:C34H38N4O6Colore e forma:SolidPeso molecolare:598.69Desirudin
CAS:Desirudin (CGP 39393) inhibits thrombin, prevents thrombosis, and is used in thrombocytopenia research.Colore e forma:SolidAA9 TG2 inhibitor
CAS:AA9 is a novel transglutaminase (TG2) inhibitor.Formula:C32H36N4O5Colore e forma:SolidPeso molecolare:556.65STOCK2S-26016
CAS:WNK-IN-B, a cell-permeable diaminoacridine, selectively inhibits WNK signaling in mpkDCT/MOVAS by targeting SPAK/OSR1 CCT domain.Formula:C20H19N3O2Colore e forma:SolidPeso molecolare:333.38Desethyl KBT-3022
CAS:Desethyl KBT-3022 is an active metabolite of the antiplatelet compound KBT-3022.Formula:C23H20N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:420.48IMB-26
CAS:IMB-26 is an HCV inhibitor (EC50: 2.1 μM) and has shown potent anti-HCV effects.Formula:C20H23BrN2O6Colore e forma:SolidPeso molecolare:467.31MDL-101146, (S)-
CAS:MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.Formula:C29H37F5N4O6Purezza:98%Colore e forma:SolidPeso molecolare:632.62U 27391
CAS:U 27391 is a metalloproteinase inhibitor. It acts by inhibits the action of human recombinant interleukin-1beta and glycosaminoglycan synthesis.Formula:C23H36N4O5Purezza:98%Colore e forma:SolidPeso molecolare:448.56LB-30057
CAS:LB-30057 is used as an oral thrombin inhibitor.Formula:C26H31N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:493.62BMS-986094
CAS:INX 08189 is an RNA-directed RNA polymerase (NS5B) inhibitor.Formula:C30H39N6O9PColore e forma:SolidPeso molecolare:658.64FK-448 Free base
CAS:FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.Formula:C25H30N2O3Purezza:98%Colore e forma:SolidPeso molecolare:406.52KIN1400
CAS:KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.Formula:C24H17F2N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:449.47HCV-IN-37
CAS:HCV-IN-37: potent HCV inhibitor, stable in rat plasma post-oral dose (15 mg/kg), blocks virus entry phase.Formula:C31H35F2N5Colore e forma:SolidPeso molecolare:515.64Batimastat sodium salt
CAS:Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).Formula:C23H31N3NaO4S2Purezza:98%Colore e forma:SolidPeso molecolare:500.63LY 135305
CAS:LY 135305 is a inhibition of spontaneous metastasis.Formula:C19H20ClNPurezza:98%Colore e forma:SolidPeso molecolare:297.82Thrombin inhibitor 6
CAS:Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.Formula:C18H19ClN4O2SColore e forma:SolidPeso molecolare:390.89Ono-3307 mesylate
CAS:no-3307 mesylate is a protease inhibitor that inhibits a variety of proteases and may be used to study pancreatitis.Formula:C15H18N4O7S2Purezza:97.60% - 98.16%Colore e forma:SolidPeso molecolare:430.46RS-104966
CAS:RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.Formula:C19H21NO6SPurezza:98%Colore e forma:SolidPeso molecolare:391.44BR351 precursor
CAS:BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).Formula:C27H32N2O8S2Purezza:98%Colore e forma:SolidPeso molecolare:576.68WNK-IN-7
CAS:WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.Formula:C26H29N3OPurezza:98%Colore e forma:SolidPeso molecolare:399.53BAY-678 racemate
CAS:BAY-678 racemate: orally active, selective cell-permeable HNE inhibitor with IC50 of 20 nM.Formula:C20H15F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:400.35PTIQ
CAS:MMP-3 expression inhibitorFormula:C13H17NO3Purezza:98%Colore e forma:SolidPeso molecolare:235.28K 579
CAS:K 579 is a dipeptidyl peptidase IV inhibitor.Formula:C17H24N6OPurezza:98%Colore e forma:SolidPeso molecolare:328.41TNK2-IN-1
CAS:TNK2-IN-1 is a TNK2 inhibitor (IC50: 224 nM) that can be used in cancer research.Formula:C23H24N6O2Colore e forma:SolidPeso molecolare:416.48GSK-2793660
CAS:GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.Formula:C20H27N3O3Purezza:98%Colore e forma:SolidPeso molecolare:357.45Epostatin
CAS:Epostatin is a new dipeptidyl peptidase II (DPP-II, EC 3.4.14.2) inhibitor.Formula:C23H33N3O5Purezza:98%Colore e forma:SolidPeso molecolare:431.53WAY-151693
CAS:WAY-151693 is an inhibitor of human collagenase-3 (MMP-13).Formula:C21H22ClN3O5SColore e forma:SolidPeso molecolare:463.93Nucleoside-Analog-1
CAS:Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.Formula:C9H9N5O5Purezza:98%Colore e forma:SolidPeso molecolare:267.2YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurezza:99.65%Colore e forma:SolidPeso molecolare:372.86ND-336
CAS:ND-336 selectively inhibits MMP-2, MMP-9, MMP-14, boosts diabetic wound healing, reduces inflammation, and promotes angiogenesis and skin repair.Formula:C16H18ClNO3S2Colore e forma:SolidPeso molecolare:371.9Bz-D-Arg-pNA hydrochloride
CAS:Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor.Formula:C19H23ClN6O4Colore e forma:SolidPeso molecolare:434.88NVP DPP 728 dihydrochloride
CAS:NVP-DPP728 is a reversible DPP-IV inhibitor with a K i of 11 nM, enhancing insulin release by preventing GLP-1 degradation, used for diabetes research.Formula:C15H18N6OColore e forma:SolidPeso molecolare:298.34GLS1 Inhibitor
CAS:GLS1 inhibitor blocks glutaminase 1 (IC50=0.021 μM), hinders NCI H1703 NSCLC cell growth in vitro (GI50=0.011 μM), and suppresses tumors in mice.Formula:C19H21N7O2SColore e forma:SolidPeso molecolare:411.48Nucleoside-Analog-2
CAS:Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.Formula:C9H11N5O6Purezza:98%Colore e forma:SolidPeso molecolare:285.21LY 806303
CAS:LY 806303 is a highly selective thrombin inhibitor.Formula:C16H14O5SPurezza:98%Colore e forma:SolidPeso molecolare:318.34Evogliptin HCl
CAS:Evogliptin (DA-1229), a DPP4 inhibitor, enhances insulin sensitivity and delays diabetes onset.Formula:C19H27ClF3N3O3Colore e forma:SolidPeso molecolare:437.88PSI-7409 tetrasodium
CAS:PSI-7409 tetrasodium, a sofosbuvir metabolite, inhibits GT 1b, 2a, 3a, 4a NS5B polymerases with IC50s of 1.6, 2.8, 0.7, 2.6 μM.Formula:C10H16FN2Na4O14P3Purezza:98%Colore e forma:SolidPeso molecolare:592.117Thrombin Inhibitor 2
CAS:Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.Formula:C19H16ClF3N6O2Purezza:98%Colore e forma:SolidPeso molecolare:452.82Alvelestat tosylate
CAS:Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.Formula:C32H30F3N5O7S2Purezza:98%Colore e forma:SolidPeso molecolare:717.73DPP-4-IN-2
CAS:DPP-4-IN-2, analog of Alogliptin with 79 nM IC50, is a research tool for diabetes.Formula:C18H18N6OColore e forma:SolidPeso molecolare:334.38Tyrosinase-IN-8
Tyrosinase-IN-8, a potent inhibitor of tyrosinase, demonstrates an inhibitory concentration (IC 50) value of 1.6 µM and exhibits low cytotoxicity whileFormula:C16H12O4Colore e forma:SolidPeso molecolare:268.26SQ 32602
CAS:SQ 32602 is a cathepsin E inhibitor.Formula:C32H52N3O7PColore e forma:SolidPeso molecolare:621.74SJA6017
CAS:SJA6017: inhibits calpain-1/2, cathepsins B/L; prevents apoptosis, protects spinal cord, boosts function. IC50s: 7.5-78 nM.Formula:C17H25FN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:372.45CP-471474
CAS:MMP inhibitor with IC50: MMP-2 (0.7 nM), MMP-13 (0.9 nM), MMP-9 (13 nM), MMP-3 (16 nM), MMP-1 (1170 nM); reduces heart dilation post-infarct.Formula:C16H17FN2O5SPurezza:98%Colore e forma:SolidPeso molecolare:368.38Sheng Gelieting
CAS:CGT-8012 inhibits DP-IV enzyme, aiding type II diabetes research, with an IC50 of 87 nM.Formula:C17H16F6N4OColore e forma:SolidPeso molecolare:406.33Tec-IN-21
CAS:Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).Formula:C16H15ClN4O2SPurezza:98%Colore e forma:SolidPeso molecolare:362.83Cysteine Protease inhibitor hydrochloride
CAS:Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.Formula:C18H15ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:338.79JNJ-10329670
CAS:JNJ 10329670 is a highly potent (Ki of approximately 30 nM), nonpeptidic, noncovalent inhibitor of human cathepsin S with immunosuppressive activity.Formula:C30H34ClF3N6O3SColore e forma:SolidPeso molecolare:651.14HCV-IN-33
CAS:HCV-IN-33 (Compound (S)-3i) is an inhibitor of HCV entry.Formula:C31H36ClN5Colore e forma:SolidPeso molecolare:514.1Gü2602
CAS:Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for matureFormula:C16H22N4O3Colore e forma:SolidPeso molecolare:318.37
