PAI-1
Il Plasminogen Activator Inhibitor-1 (PAI-1) è un inibitore delle serin proteasi che regola la fibrinolisi inibendo l'attivatore tissutale del plasminogeno (tPA) e l'urochinasi (uPA). Livelli elevati di PAI-1 sono associati a un aumento del rischio di trombosi, malattie cardiovascolari e sindrome metabolica. Gli inibitori di PAI-1 sono oggetto di ricerca per il loro potenziale nel trattamento di queste condizioni. Presso CymitQuimica, offriamo inibitori di PAI-1 per supportare la tua ricerca in ematologia, salute cardiovascolare e malattie metaboliche.
Trovati 30 prodotti per "PAI-1".
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Formula:C32H47N5O6SPurezza:99.41%Colore e forma:White SolidPeso molecolare:629.81Ref: TM-T13257
1mg60,00€2mg89,00€5mg138,00€1mL*10mM (DMSO)155,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€Anti-SERPINE1 Antibody
Anti-SERPINE1 Antibody targets PAI-1, promoting fibrinolysis and reducing fibrosis by neutralizing its activity, and blocks PAI-1-mediated tumor immune evasion.CT140
CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.Colore e forma:Odour LiquidGGACK hydrochloride
GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Formula:C14H26Cl2N6O5Colore e forma:SolidPeso molecolare:428.13417Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Colore e forma:Yellow SolidUK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Formula:C72H105N19O25S3Colore e forma:SolidPeso molecolare:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Formula:C77H118N26O25S3Colore e forma:SolidPeso molecolare:1904.11Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFormula:C39H62N10O15Purezza:99.97%Colore e forma:SolidPeso molecolare:910.97D-Val-Leu-Arg-pNA hydrochloride
CAS:D-Val-Leu-Arg-pNA hydrochloride is a substrate for glandular kallikrein. It can be utilized to measure the activity of plasminogen activators and plasmin. This compound is also employed in studying fibrinolytic activity in various organisms, such as bacteria and worms.Formula:C23H39ClN8O5Peso molecolare:543.07D-Val-Leu-Lys-AMC TFA
D-Val-Leu-Lys-AMC TFA is a selective fluorescent peptide substrate for plasmin. It is employed for the quantitative assessment of plasmin enzymatic activity. The excitation wavelength is 360-380 nm, and the emission wavelength is 440-460 nm.6-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Formula:C6H13NO2Colore e forma:SolidPeso molecolare:131.17CDE-096
CAS:CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Formula:C25H20F3NO12Purezza:99.08%Colore e forma:Yellow SolidPeso molecolare:583.42Ref: TM-T25217
1mg57,00€5mg123,00€1mL*10mM (DMSO)158,00€10mg200,00€25mg423,00€50mg677,00€100mg1.063,00€Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Formula:C24H16F3NO4Purezza:99.16% - 99.93%Colore e forma:SolidPeso molecolare:439.38Ref: TM-T2030
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg145,00€50mg245,00€100mg485,00€500mg1.035,00€TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Formula:C24H20N2O6S4Purezza:96.91%Colore e forma:SolidPeso molecolare:560.69UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Formula:C14H16ClN5O4SPurezza:95.81% - 99.77%Colore e forma:SolidPeso molecolare:385.83Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Formula:C16H20O6Purezza:99.8% - 99.85%Colore e forma:SolidPeso molecolare:308.33Ref: TM-T4S0592
2mg37,00€5mg52,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg320,00€TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Formula:C28H27ClN3NaO5Purezza:98.8% - 99.74%Colore e forma:SolidPeso molecolare:543.98Ref: TM-T4255
2mg39,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg93,00€25mg160,00€50mg231,00€100mg334,00€200mg465,00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purezza:99.33% - 99.86%Colore e forma:White SolidPeso molecolare:316.35TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formula:C21H17ClN2O6Purezza:97.62% - 99.09%Colore e forma:White SolidPeso molecolare:428.82MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Formula:C10H10F3N3O3Colore e forma:SolidPeso molecolare:277.20
