PAI-1
Il Plasminogen Activator Inhibitor-1 (PAI-1) è un inibitore delle serin proteasi che regola la fibrinolisi inibendo l'attivatore tissutale del plasminogeno (tPA) e l'urochinasi (uPA). Livelli elevati di PAI-1 sono associati a un aumento del rischio di trombosi, malattie cardiovascolari e sindrome metabolica. Gli inibitori di PAI-1 sono oggetto di ricerca per il loro potenziale nel trattamento di queste condizioni. Presso CymitQuimica, offriamo inibitori di PAI-1 per supportare la tua ricerca in ematologia, salute cardiovascolare e malattie metaboliche.
Trovati 31 prodotti per "PAI-1".
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Formula:C32H47N5O6SPurezza:99.41%Colore e forma:White SolidPeso molecolare:629.81PAI-1-IN-1
CAS:PAI-1-IN-1 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that affects fibrinolytic activity by modulating PAI-1-mediated inhibition of tPA/uPA.Formula:C23H14ClN2NaO3Purezza:99.42% - 99.59%Peso molecolare:424.81D-Val-Leu-Lys-AMC TFA
D-Val-Leu-Lys-AMC TFA is a selective fluorescent peptide substrate for plasmin. It is employed for the quantitative assessment of plasmin enzymatic activity. The excitation wavelength is 360-380 nm, and the emission wavelength is 440-460 nm.PAI-1-IN-2
CAS:5-Chloro-2-[[[2-[[3-(furan-2-yl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid is an oral PAI-1 inhibitor improving metabolism and hepatic steatosis.Formula:C21H17ClN2O6Purezza:98.78%Peso molecolare:428.82Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Colore e forma:Yellow SolidAngstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFormula:C39H62N10O15Purezza:99.97%Colore e forma:SolidPeso molecolare:910.9676Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Formula:C77H118N26O25S3Colore e forma:SolidPeso molecolare:1904.11UK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Formula:C72H105N19O25S3Colore e forma:SolidPeso molecolare:1732.91Stromab
Stromab (DS9231; TS-23; CSL-301) is a human-derived IgG1 monoclonal antibody (mAb) that targets SerpinF2. It can be utilized for research in ischemic stroke, pulmonary embolism, myocardial infarction, and thrombosis. The suggested isotype control is Human IgG1 lambda, Isotype Control.6-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Formula:C6H13NO2Colore e forma:SolidPeso molecolare:131.1729CDE-096
CAS:CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Formula:C25H20F3NO12Purezza:99.08%Colore e forma:Yellow SolidPeso molecolare:583.42Anti-Human SERPINE1 Antibody
Anti-SERPINE1 Antibody targets PAI-1, promoting fibrinolysis and reducing fibrosis by neutralizing its activity, and blocks PAI-1-mediated tumor immune evasion.Purezza:95% - 97.6% (SDS-PAGE); 99.1% (SEC-HPLC)Peso molecolare:146.07 kDa (Predicted)TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Formula:C24H20N2O6S4Purezza:96.91%Colore e forma:SolidPeso molecolare:560.69UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Formula:C14H16ClN5O4SPurezza:95.81% - 99.77%Colore e forma:SolidPeso molecolare:385.826Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purezza:99.33% - 99.86%Colore e forma:White SolidPeso molecolare:316.3484Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Formula:C24H16F3NO4Purezza:99.16% - 99.93%Colore e forma:SolidPeso molecolare:439.38Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Formula:C16H20O6Purezza:99.8% - 99.85%Colore e forma:SolidPeso molecolare:308.3264TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Formula:C28H27ClN3NaO5Purezza:98.8% - 99.74%Colore e forma:SolidPeso molecolare:543.98TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formula:C21H17ClN2O6Purezza:0.998% - 99.23%Colore e forma:White SolidPeso molecolare:428.82MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Formula:C10H10F3N3O3Colore e forma:SolidPeso molecolare:277.20
