Proteasoma
Gli inibitori del proteasoma sono composti che inibiscono il proteasoma, un grande complesso proteico responsabile della degradazione delle proteine non desiderate o danneggiate all'interno della cellula. L'inibizione del proteasoma porta all'accumulo di proteine, che può indurre l'arresto del ciclo cellulare e l'apoptosi, in particolare nelle cellule che si dividono rapidamente, come le cellule tumorali. Gli inibitori del proteasoma sono fondamentali nella ricerca e nella terapia del cancro, specialmente nel trattamento del mieloma multiplo e di altre neoplasie ematologiche. Presso CymitQuimica, offriamo inibitori del proteasoma per supportare la tua ricerca in oncologia, biologia cellulare e sviluppo di farmaci.
Trovati 72 prodotti per "Proteasoma".
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Gabexate mesylate
CAS:Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Formula:C17H27N3O7SPurezza:99.2% - 99.64%Colore e forma:White CrystalPeso molecolare:417.48UT-34
CAS:UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wildFormula:C15H12F4N4O2Purezza:98.12%Colore e forma:SolidPeso molecolare:356.275RAMB4
CAS:RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.Formula:C19H13Cl4NOPurezza:98.89% - 99.38%Colore e forma:Yellow SolidPeso molecolare:413.12RA190
CAS:RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.Formula:C28H23Cl5N2O2Purezza:97.7%Colore e forma:SolidPeso molecolare:596.759Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formula:C18H24ClN3O7Purezza:99.44% - 99.98%Colore e forma:SolidPeso molecolare:429.852Pepstatin
CAS:Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formula:C34H63N5O9Purezza:96.74% - 99.94%Colore e forma:SolidPeso molecolare:685.8921ML604440
CAS:ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.Formula:C17H24BF3N2O4Purezza:97.06%Colore e forma:SolidPeso molecolare:388.19Protease Inhibitor Library
A unique collection of xnum protease and proteasome inhibitors for research in chemical genomics, and drug screening;Colore e forma:Odour SolidPhepropeptin B
CAS:Phepropeptin B is a secondary metabolite derived from microorganisms, functioning as a proteasome (proteasome) inhibitor with an IC50 value of 11 μg/mL.Formula:C40H56N6O6Colore e forma:SolidPeso molecolare:716.91Phepropeptin C
CAS:Phepropeptin C is a microbial secondary metabolite that acts as a proteasome (proteasome) inhibitor, with an IC50 of 12.5 μg/mL.Formula:C38H60N6O6Colore e forma:SolidPeso molecolare:696.92Z-Leu-Leu-Tyr-COCHO
CAS:Z-Leu-Leu-Tyr-COCHO is a potent inhibitor of chymotrypsin-like activity, exhibiting a Ki value of 3.0 nM [1].Formula:C30H39N3O7Purezza:98%Colore e forma:SolidPeso molecolare:553.65Dazcapistat
CAS:Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.Formula:C21H18FN3O4Purezza:99.11%Colore e forma:SolidPeso molecolare:395.3837Proteasome-IN-7
Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.Formula:C48H56N6O10SColore e forma:SolidPeso molecolare:909.06Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Colore e forma:Odour SolidBortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Colore e forma:Odour SolidLXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.Formula:C27H22FN7O6Purezza:99.89%Colore e forma:SolidPeso molecolare:559.51Ac-Nle-Pro-Nle-Asp-AMC
CAS:Ac-Nle-Pro-Nle-Asp-AMC: 26S proteasome substrate for caspase-like activity analysis.Formula:C33H45N5O9Peso molecolare:655.7385Z-Gly-Pro-Phe-Leu-CHO
CAS:Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) ofFormula:C30H38N4O6Purezza:98%Colore e forma:SolidPeso molecolare:550.65Suc-Leu-Leu-Val-Tyr-AMC
CAS:Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic tetrapeptide substrate for 20S proteasome and chymotrypsin-like proteases, used in drug screening.Formula:C40H53N5O10Purezza:98%Colore e forma:SolidPeso molecolare:763.8763Phepropeptin A
CAS:Phepropeptin A is a secondary metabolite produced by microorganisms and acts as a proteasome (proteasome) inhibitor, with an IC50 of 21 μg/mL.Formula:C37H58N6O6Colore e forma:SolidPeso molecolare:682.89
