Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1095 prodotti di "Proteasi/Proteasoma"
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HIV-1 TAT (48-60) Acetate
Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.Formula:C72H135N35O18Purezza:99.93%Colore e forma:SoildPeso molecolare:1779.07L-Methionine-DL-sulfoximine
CAS:MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.Formula:C5H12N2O3SPurezza:99.56% - ≥98%Colore e forma:White Crystalline PowderPeso molecolare:180.23Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.Formula:C25H25ClF6N6O2Colore e forma:SolidPeso molecolare:590.95Proteasome-IN-7
Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.Formula:C48H56N6O10SColore e forma:SolidPeso molecolare:909.06GSK2818713
CAS:GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.Formula:C46H56N8O8Colore e forma:SolidPeso molecolare:849.002Roseltide rT1
CAS:Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.Formula:C110H177N31O31S6Colore e forma:SolidPeso molecolare:2622.16MeOSuc-AAPA-CMK
MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].Formula:C20H31ClN4O8Colore e forma:SolidPeso molecolare:490.94Cajaninstilbene acid
CAS:Cajaninstilbene acid is a useful organic compound for research related to life sciences. The catalog number is T124035 and the CAS number is 87402-84-4.Formula:C21H22O4Colore e forma:SolidPeso molecolare:338.403Ac-PLVE-FMK
CAS:Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].Formula:C25H41FN4O7Purezza:98%Colore e forma:SolidPeso molecolare:528.61MMP-9/MMP-13 Inhibitor I
CAS:MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.Formula:C25H25N3O6SColore e forma:SolidPeso molecolare:495.55Pirmitegravir
CAS:<p>Pirmitegravir (STP0404) is a potent ALLINI, blocks LEDGF/p75 site, shows antiviral action against HIV.</p>Formula:C27H31ClN4O3Purezza:99.79% - 99.79%Colore e forma:SolidPeso molecolare:495.01TMC647055 Choline salt
TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).Formula:C37H53N5O8SPurezza:98%Colore e forma:SolidPeso molecolare:727.91Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFormula:C24H35N5O4·xC2HF3O2Colore e forma:SolidSofosbuvir impurity J
CAS:Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H30FN4O8PPurezza:98%Colore e forma:SolidPeso molecolare:528.47DPP8/9-IN-1
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.Colore e forma:Odour SolidVD2173
CAS:<p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>Formula:C31H45N9O6SColore e forma:SolidPeso molecolare:671.81FFAGLDD TFA
<p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>Formula:C39H50F3N7O14Purezza:98%Colore e forma:SolidPeso molecolare:897.85Radalbuvir
CAS:Radalbuvir (GS-9669) is an investigational antiviral agent for the treatment of hepatitis C virus (HCV) infection as an NS5B inhibitor.Formula:C30H41NO6SColore e forma:SolidPeso molecolare:543.71PF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Formula:C25H20N2O3SPurezza:99.35%Colore e forma:SolidPeso molecolare:428.5GCPII-IN-1
CAS:<p>GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.</p>Formula:C12H21N3O7Colore e forma:SolidPeso molecolare:319.314Z-Leu-Tyr-Chloromethylketone
CAS:Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].Formula:C24H29ClN2O5Colore e forma:SolidPeso molecolare:460.95Ala-Phe-Pro-pNA TFA
Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.Colore e forma:Odour SolidPseudostellarin G
CAS:Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Formula:C42H56N8O9Colore e forma:SolidPeso molecolare:816.94Monodes(N-carboxymethyl)valine Daclatasvir
CAS:Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.Formula:C33H39N7O3Colore e forma:SolidPeso molecolare:581.71Calpain Inhibitor-1
CAS:Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Formula:C19H17FN6O5SColore e forma:SolidPeso molecolare:460.44HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormula:C14H10N4O4SPurezza:99.33%Colore e forma:SolidPeso molecolare:330.32Ref: TM-T9854
1mg75,00€5mg169,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€500mgPrezzo su richiestamidesteine
CAS:Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.Formula:C12H13NO3S3Purezza:99.87% - 99.98%Colore e forma:SolidPeso molecolare:315.43L 659286
CAS:L 659286 is one kind of cephalosporin derivative.Formula:C17H21N5O7S2Colore e forma:SolidPeso molecolare:471.51Berotralstat
CAS:Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.Formula:C30H26F4N6OColore e forma:SolidPeso molecolare:562.56EP 171
CAS:EP 171 is a potent agonist of TP-receptors.Formula:C23H29FO5Colore e forma:SolidPeso molecolare:404.47Lonodelestat TFA
Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.Formula:C73H112F3N15O21Colore e forma:SolidPeso molecolare:1592.75Rivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).Formula:C56H83N9O15Colore e forma:SolidPeso molecolare:1122.31CRA-2059 TFA
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Colore e forma:SolidNIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Formula:C62H111N11O12Purezza:98%Colore e forma:SolidPeso molecolare:1202.635Nostopeptin B
CAS:Nostopeptin B is an inhibitor of elastase.Formula:C46H70N8O12Colore e forma:SolidPeso molecolare:927.11Alisporivir
CAS:Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.Formula:C63H113N11O12Purezza:99.95%Colore e forma:SolidPeso molecolare:1216.64Dutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Formula:C14H26BN3O9Purezza:98%Colore e forma:SolidPeso molecolare:391.18Obtusifolin-2-O-glucoside
CAS:Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].Formula:C22H22O10Colore e forma:SolidPeso molecolare:446.4Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Colore e forma:Odour SolidFotagliptin
CAS:Fotagliptin is a dipeptidyl peptidase IV inhibitor.Formula:C17H19FN6OColore e forma:SolidPeso molecolare:342.376-Acetylnimbandiol
CAS:6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.Formula:C28H34O8Colore e forma:SolidPeso molecolare:498.567-Methoxy obtusifolin
CAS:7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentrationFormula:C17H14O6Colore e forma:SolidPeso molecolare:314.29α 1(I) Collagen (614-639), human
CAS:This is a peptide inhibitor of collagen fibrillar matrix assembly.Formula:C134H189N37O39Purezza:98%Colore e forma:SolidPeso molecolare:2942.16Cathepsin Inhibitor 4
<p>Cathepsin Inhibitor 4 (Compound 45) is a selective inhibitor of Cathepsin S, with a Ki value of 0.04 nM.</p>Formula:C24H35N3O5Peso molecolare:445.25767Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofColore e forma:Odour SolidTrivalent hydroxyarsinothricn
Trivalent hydroxyarsinothricn (R-AST-OH) is a covalent and irreversible inhibitor of kidney-type glutaminase (KGA). It binds to the glutamine binding site and forms a covalent bond with the cysteine residue at the active site. This compound selectively kills triple-negative breast cancer (TNBC) cells without being cytotoxic to control cell lines. KGA is an enzyme that regulates glutamine metabolism and is associated with tumor malignancy.Formula:C4H10AsNO4Peso molecolare:210.98258Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Colore e forma:Odour SolidChetoseminudin B
CAS:Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].Formula:C17H21N3O3S2Colore e forma:SolidPeso molecolare:379.5HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Colore e forma:Odour SolidMMP-3 Inhibitor
CAS:MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.Formula:C27H46N10O9SPurezza:98.87%Colore e forma:SolidPeso molecolare:686.78Ref: TM-T37048
1mg81,00€5mg208,00€10mg309,00€25mg525,00€50mg757,00€100mg1.035,00€500mg2.110,00€1mL*10mM (DMSO)221,00€
