Proteasoma

Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat …

Ixazomib citrate is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation …

Bortezomib (PS-341) is a potent 20S proteasome inhibitor (Ki: 0.6 nM, in a cell-free assay).

Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome …

Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.

Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.

RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.

PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 …

Proteasome-IN-1 is an inhibitor of proteasome.

MUN57694 is an inhibitor of 26S proteasome.

Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing …

(R)-MG-132 is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than …

TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S …

ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.

Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of …

Oprozomib (ONX 0912) , an inhibitor for CT-L activity of 20S proteasome β5(IC50=36 nM)/LMP7(IC50=82 nM), …

MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The …

CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). …

Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent that is used in treatment of …

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, …

KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 …

DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.

MLN2238, a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site …

Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is …

VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 …

Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and …

Aprotinin a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases …

PSI is a proteasome inhibitor.

AOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis …

MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain …

PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.

LMP7-IN-1 may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases …

AZD7986 is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 …

UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 …

ONX-0914 is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive …

Celastrol is an effective proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome(IC50=2.5 …

PI-1840( IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome …

N-(4-fluorophenyl)benzo[d]thiazol-2-amine is a protein kinase inhibitor.

AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). …