CymitQuimica logo
Cellule staminali e Derivati

Cellule staminali e Derivati

Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.

Sottocategorie di "Cellule staminali e Derivati"

Mostrare 2 più sottocategorie

Trovati 679 prodotti di "Cellule staminali e Derivati"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • STAT3-IN-35
    Targetmol
    + Info

    STAT3-IN-35

    CAS:
    STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.
    Formula:C21H23NO4
    Colore e forma:Solid
    Peso molecolare:353.41

    Ref: TM-T200468

  • PF-06648671
    Targetmol
    + Info

    PF-06648671

    CAS:
    PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.
    Formula:C25H23ClF4N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:538.92

    Ref: TM-T24621

  • TEAD-IN-20
    Targetmol
    + Info

    TEAD-IN-20

    CAS:
    TEAD-IN-20 is a TEAD inhibitor with IC50 values of 0.021 μM in TEAD4 FRET and 0.044 μM in TEAD4 MCF7-Tead cell lines. It has potential applications in cancer research.
    Formula:C20H19F3N4O3
    Colore e forma:Solid
    Peso molecolare:420.39

    Ref: TM-T207373

  • AZ-3
    Targetmol
    + Info

    AZ-3

    CAS:
    AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
    Formula:C20H28FN7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:385.48

    Ref: TM-T10424

  • Logo CymitQuimica
    Targetmol
    + Info

    JAK-IN-19

    JAK-IN-19 inhibits JAK (pIC50: 7.2, 7.7), less so for VEGFR2 (7.0) and Aurora B (5.8).
    Formula:C26H36FN5O2
    Colore e forma:Solid
    Peso molecolare:469.59

    Ref: TM-T63026

  • PF-06442609
    Targetmol
    + Info

    PF-06442609

    CAS:
    PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.
    Formula:C24H24F4N4O3
    Peso molecolare:492.47

    Ref: TM-T210322

  • TGFβ1-IN-1
    Targetmol
    + Info

    TGFβ1-IN-1

    CAS:
    TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.
    Formula:C22H24N2O3
    Purezza:99.89% - 99.89%
    Colore e forma:Solid
    Peso molecolare:364.438

    Ref: TM-T61389

  • PF-06263276
    Targetmol
    + Info

    PF-06263276

    CAS:
    PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).
    Formula:C31H31FN8O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:566.63

    Ref: TM-T16488

  • iBFAR2
    Targetmol
    + Info

    iBFAR2

    CAS:
    <p>iBFAR2, an inhibitor of BFAR, restores the CD8+ tumor-resident memory T cell subset against solid tumors. It promotes the binding of JAK2-STAT1 and enhances the phosphorylation of STAT1.</p>
    Formula:C19H15F3N2O2
    Colore e forma:Solid
    Peso molecolare:360.33

    Ref: TM-T204531

  • JAK2-IN-11
    Targetmol
    + Info

    JAK2-IN-11

    CAS:
    JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 of ≤10 nM against JH2 BIND WT/V617F. This compound effectively suppresses tumor growth.
    Formula:C31H31F3N8O4
    Colore e forma:Solid
    Peso molecolare:639.64

    Ref: TM-T201601

  • MGD-28
    Targetmol
    + Info

    MGD-28

    CAS:
    MGD-28 is a Cullin-CRBN-dependent IKZF family protein degrader for IKZF1 (Ikaros), IKZF2 (Helios), IKZF3 (Aiolos) ,and CK1α, antiproliferative.
    Formula:C33H34FN7O3
    Purezza:99.39%
    Colore e forma:Solid
    Peso molecolare:595.67

    Ref: TM-T201415

  • (R)-9b
    Targetmol
    + Info

    (R)-9b

    CAS:
    (R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R)-9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.
    Formula:C20H27ClN6O
    Colore e forma:Solid
    Peso molecolare:402.92

    Ref: TM-T201776

  • lirucitinib
    Targetmol
    + Info

    lirucitinib

    CAS:
    <p>Lirucitinib is a JAK inhibitor known for its anti-inflammatory properties.</p>
    Formula:C16H25N5OS
    Colore e forma:Solid
    Peso molecolare:335.468

    Ref: TM-T205259

  • TEAD-IN-10
    Targetmol
    + Info

    TEAD-IN-10

    CAS:
    <p>TEAD-IN-10 (compound 15), a covalent inhibitor, exhibits selective and potent inhibitory activity against TEAD1 (IC 50 =14 nM), TEAD2 (IC 50 =179 nM), and TEAD3 (IC 50 =4 nM). This compound is utilized in cancer research [1].</p>
    Formula:C15H14F3NO
    Colore e forma:Solid
    Peso molecolare:281.27

    Ref: TM-T87500

  • γ-Secretase modulator 11 hydrochloride
    Targetmol
    + Info

    γ-Secretase modulator 11 hydrochloride

    CAS:
    <p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>
    Formula:C28H23ClF2N4O2
    Colore e forma:Solid
    Peso molecolare:520.96

    Ref: TM-T63638

  • YAP/TAZ inhibitor-3
    Targetmol
    + Info

    YAP/TAZ inhibitor-3

    CAS:
    YAP/TAZ inhibitor-3 (Compound 24) is a YAP/TAZ inhibitor applicable for relevant research within the life sciences field.
    Formula:C21H18F3NO3
    Purezza:99.63%
    Colore e forma:Solid
    Peso molecolare:389.37

    Ref: TM-T87651

  • Logo CymitQuimica
    Targetmol
    + Info

    BPN-15606 besylate

    BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).
    Formula:C29H29FN6O4S
    Colore e forma:Solid
    Peso molecolare:576.64

    Ref: TM-T64081

  • M3686
    Targetmol
    + Info

    M3686

    CAS:
    M3686 (Compound 29) is a potent and selective TEAD1 inhibitor with an IC50 value of 51 nM. It exhibits weaker binding activity toward TEAD3. M3686 significantly inhibits the cellular activity of YAP-dependent NCI-H226 cell lines, with an IC50 value of 0.06 μM, and demonstrates strong antitumor effects in the NCI-H226 xenograft model.
    Formula:C21H18F3N5O2
    Colore e forma:Solid
    Peso molecolare:429.395

    Ref: TM-T205477

  • MYF-03-176
    Targetmol
    + Info

    MYF-03-176

    CAS:
    MYF-03-176 is an orally active TEAD1/3/4 inhibitor with IC₅₀ values of 47/32/71 nM. inhibits TEAD transcriptional activity and cancer cell growth, antitumour.
    Formula:C19H18F4N4O2
    Colore e forma:Solid
    Peso molecolare:410.37

    Ref: TM-T62074

  • Milpecitinib
    Targetmol
    + Info

    Milpecitinib

    CAS:
    <p>Milpecitinib (Compound 21a) is a potent and selective Janus tyrosine kinase (JAK) inhibitor with anti-inflammatory properties. It shows promise for research in cancer and inflammatory diseases.</p>
    Formula:C20H20N4O2S
    Colore e forma:Solid
    Peso molecolare:380.463

    Ref: TM-T205326