CymitQuimica logo
Cellule staminali e Derivati

Cellule staminali e Derivati

Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.

Sottocategorie di "Cellule staminali e Derivati"

Mostrare 2 più sottocategorie

Trovati 679 prodotti di "Cellule staminali e Derivati"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • JAK3-IN-7
    Targetmol
    + Info

    JAK3-IN-7

    CAS:
    JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after
    Formula:C17H20N6O
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:324.38

    Ref: TM-T10009

  • MYF-03-176
    Targetmol
    + Info

    MYF-03-176

    CAS:
    MYF-03-176 is an orally active TEAD1/3/4 inhibitor with IC₅₀ values of 47/32/71 nM. inhibits TEAD transcriptional activity and cancer cell growth, antitumour.
    Formula:C19H18F4N4O2
    Colore e forma:Solid
    Peso molecolare:410.37

    Ref: TM-T62074

  • JAK1-IN-9
    Targetmol
    + Info

    JAK1-IN-9

    CAS:
    JAK1-IN-9 (compound 23a) is a potent, selective inhibitor of JAK1, demonstrating an IC50 of 72 nM.
    Formula:C16H13IN6
    Colore e forma:Solid
    Peso molecolare:416.22

    Ref: TM-T62155

  • (Rac)-SAG
    Targetmol
    + Info

    (Rac)-SAG

    CAS:
    (Rac)-SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC₅₀ = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamine's inhibition of Smo [1] [2] [3].
    Formula:C28H28ClN3OS
    Colore e forma:Solid
    Peso molecolare:490.06

    Ref: TM-T85362

  • Tyk2-IN-14
    Targetmol
    + Info

    Tyk2-IN-14

    CAS:
    Tyk2-IN-14, a small molecule inhibitor of TYK2, is significant in treating inflammatory diseases and conditions linked to hypersecretion of IFNa and interferons [1].
    Formula:C22H21N9O2
    Colore e forma:Solid
    Peso molecolare:443.46

    Ref: TM-T87583

  • AJI-214
    Targetmol
    + Info

    AJI-214

    CAS:
    AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).
    Formula:C17H13ClFN5O
    Colore e forma:Solid
    Peso molecolare:357.77

    Ref: TM-T200387

  • Tyk2-IN-17
    Targetmol
    + Info

    Tyk2-IN-17

    CAS:
    <p>Tyk2-IN-17 (compound 185) effectively inhibits TYK2 [1].</p>
    Formula:C20H20F2N8O
    Colore e forma:Solid
    Peso molecolare:426.42

    Ref: TM-T87586

  • Tyk2-IN-15
    Targetmol
    + Info

    Tyk2-IN-15

    CAS:
    <p>Tyk2-IN-15 (Compound 97) is a selective inhibitor of tyrosine kinase 2 (Tyk2) with an IC50 value ≤ 10 nM for Tyk2-JH2. It is utilized in the research of inflammatory and autoimmune diseases [1].</p>
    Formula:C21H25F2N7O
    Colore e forma:Solid
    Peso molecolare:429.47

    Ref: TM-T87584

  • Logo CymitQuimica
    Targetmol
    + Info

    Kartogenin sodium

    CAS:
    Kartogenin (KGN) sodium acts as an inducer of chondrogenic tissue formation (EC 50: 100 nM). It promotes chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and modulating the CBFβ-RUNX1 transcriptional program. Additionally, Kartogenin sodium aids tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. It is extensively utilized in cell-free therapies for cartilage regeneration and protection, tendon-bone healing, wound healing, and limb development. The compound is also vital for cartilage repair, coordinating limb development, and osteoarthritis (OA) research [1] [2] [3] [4].
    Formula:C20H14NNaO3
    Peso molecolare:339.32

    Ref: TM-T86778

  • Logo CymitQuimica
    Targetmol
    + Info

    JAK-IN-23

    "JAK-IN-23: oral dual JAK/STAT & NF-κB inhibitor; JAK1 (IC50: 8.9 nM), JAK2 (15 nM), JAK3 (46.2 nM); for IBD research."
    Formula:C23H22Cl2N4O
    Colore e forma:Solid
    Peso molecolare:441.35

    Ref: TM-T62556

  • Logo CymitQuimica
    Targetmol
    + Info

    Ten01

    Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase.
    Formula:C18H20F6N4O
    Colore e forma:Solid
    Peso molecolare:422.37

    Ref: TM-T62257

  • Carboxylesterase-IN-3
    Targetmol
    + Info

    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Formula:C11H6Cl2N4OS
    Purezza:97.49% - 98.47%
    Colore e forma:Solid
    Peso molecolare:313.16

    Ref: TM-T60788

  • Tyk2-IN-10
    Targetmol
    + Info

    Tyk2-IN-10

    CAS:
    Tyk2-IN-10 acts as an inhibitor of the Tyrosine Kinase 2 (Tyk2)-mediated signaling pathway, which plays a role in inflammation regulation.
    Formula:C25H27N5O3
    Colore e forma:Solid
    Peso molecolare:445.51

    Ref: TM-T89889

  • PMMB-187
    Targetmol
    + Info

    PMMB-187

    CAS:
    PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.
    Formula:C27H23BrN2O6S2
    Colore e forma:Solid
    Peso molecolare:615.52

    Ref: TM-T200126

  • CDD-1431
    Targetmol
    + Info

    CDD-1431

    CAS:
    <p>CDD-1431 is a highly selective BMPR2 kinase inhibitor with a Kiapp of 20.6 nM. It inhibits BRE reporter gene activity, exhibiting an IC50 of 4.87 μM. BMPs regulate cellular processes across various tissue types such as the kidneys, skeletal muscle, heart, and reproductive organs, and can induce ectopic bone formation.</p>
    Formula:C33H38N8O5S
    Colore e forma:Solid
    Peso molecolare:658.77

    Ref: TM-T205082

  • TYK2 ligand 2
    Targetmol
    + Info

    TYK2 ligand 2

    CAS:
    <p>TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.</p>
    Formula:C24H20FN7O4
    Colore e forma:Solid
    Peso molecolare:489.458

    Ref: TM-T206678

  • PF-06648671
    Targetmol
    + Info

    PF-06648671

    CAS:
    PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.
    Formula:C25H23ClF4N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:538.92

    Ref: TM-T24621

  • GSK-3β inhibitor 20
    Targetmol
    + Info

    GSK-3β inhibitor 20

    CAS:
    GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.
    Formula:C22H21N5O2S
    Colore e forma:Solid
    Peso molecolare:419.50

    Ref: TM-T200457

  • DAPM
    Targetmol
    + Info

    DAPM

    CAS:
    DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.
    Formula:C20H20F2N2O4
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:390.38

    Ref: TM-T86161

  • STAT3-IN-35
    Targetmol
    + Info

    STAT3-IN-35

    CAS:
    STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.
    Formula:C21H23NO4
    Colore e forma:Solid
    Peso molecolare:353.41

    Ref: TM-T200468