Wnt/beta-catenina
Gli inibitori della via Wnt/beta-catenina sono composti che inibiscono la via di segnalazione Wnt/beta-catenina, cruciale per la regolazione dello sviluppo embrionale, della proliferazione cellulare e del mantenimento delle cellule staminali. La disfunzione di questa via è legata a vari tipi di cancro e malattie degenerative. Gli inibitori della segnalazione Wnt/beta-catenina sono preziosi per la ricerca volta a comprendere il ruolo di questa via nelle malattie e a sviluppare terapie mirate. Presso CymitQuimica, offriamo inibitori di Wnt/beta-catenina per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e ricerca sul cancro.
Trovati 63 prodotti di "Wnt/beta-catenina"
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JW74
CAS:JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formula:C24H20N6O2SPurezza:95.00%Colore e forma:SolidPeso molecolare:456.52Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurezza:99.32% - 99.85%Colore e forma:SolidPeso molecolare:289.8Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Purezza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Colore e forma:LiquidTNIK-IN-5
CAS:TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formula:C22H17N3O3Purezza:99.58%Colore e forma:SolidPeso molecolare:371.39CCT251545
CAS:<p>CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).</p>Formula:C23H24ClN5OPurezza:98.2% - 98.69%Colore e forma:SolidPeso molecolare:421.92KY1220
CAS:<p>KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.</p>Formula:C14H10N4O3SPurezza:99.9%Colore e forma:SolidPeso molecolare:314.32CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurezza:98.87%Colore e forma:SolidPeso molecolare:717.63BML-286
CAS:<p>BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.</p>Formula:C22H18N2O4Purezza:98.44%Colore e forma:SolidPeso molecolare:374.39Romosozumab
CAS:<p>Romosozumab (AMG-785) is a humanized monoclonal antibody that binds and inhibits sclerostin, which increases bone formation and decreases bone resorption.</p>Purezza:98.9% (SDS-PAGE); 98.2% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.2% (SEC-HPLC)Colore e forma:LiquidYW2036
CAS:YW2036 is an inhibitor of Wnt signaling pathway.Formula:C20H16N4OPurezza:99.94%Colore e forma:SoildPeso molecolare:328.37LP-922056
CAS:<p>LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.</p>Formula:C11H9ClN2O2S2Purezza:99.84%Colore e forma:SolidPeso molecolare:300.78Wnt/β-catenin agonist 3
CAS:<p>Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.</p>Formula:C16H15ClN4O2Purezza:99.52%Colore e forma:SolidPeso molecolare:330.77ABC99
CAS:ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.Formula:C22H21ClN4O5Purezza:99.89%Colore e forma:SoildPeso molecolare:456.88NLS-StAx-h
Wnt inhibitor; halts cancer cell growth & spread by blocking β-catenin, IC50=1.4μM, cell-permeable.Formula:C161H275N55O29Purezza:98%Colore e forma:SolidPeso molecolare:3445.26Ipafricept
CAS:Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Purezza:99.2% (SDS-PAGE); 97.4% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.4% (SEC-HPLC)Colore e forma:Liquid1(R),2(S)-epoxy Cannabidiol
CAS:<p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>Formula:C21H30O3Colore e forma:SolidPeso molecolare:330.46Tabituximab
CAS:BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.Purezza:98.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 98.7% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.5 kDaFoxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFormula:C26H42N6O12S2Purezza:98%Colore e forma:SolidPeso molecolare:694.77Wnt pathway inhibitor 3
CAS:Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studiesFormula:C21H17BrN2O5Purezza:99.94%Colore e forma:SoildPeso molecolare:457.27WIC1
CAS:<p>2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.</p>Formula:C22H23N3O3Purezza:99.82%Colore e forma:SoildPeso molecolare:377.44
