Wnt/beta-catenina
Gli inibitori della via Wnt/beta-catenina sono composti che inibiscono la via di segnalazione Wnt/beta-catenina, cruciale per la regolazione dello sviluppo embrionale, della proliferazione cellulare e del mantenimento delle cellule staminali. La disfunzione di questa via è legata a vari tipi di cancro e malattie degenerative. Gli inibitori della segnalazione Wnt/beta-catenina sono preziosi per la ricerca volta a comprendere il ruolo di questa via nelle malattie e a sviluppare terapie mirate. Presso CymitQuimica, offriamo inibitori di Wnt/beta-catenina per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e ricerca sul cancro.
Trovati 58 prodotti di "Wnt/beta-catenina"
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KY1220
CAS:KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formula:C14H10N4O3SPurezza:99.9%Colore e forma:SolidPeso molecolare:314.32Ref: TM-T15677
2mg34,00€5mg66,00€10mg101,00€25mg200,00€50mg319,00€100mg515,00€200mg702,00€1mL*10mM (DMSO)70,00€JW74
CAS:JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formula:C24H20N6O2SPurezza:95.00%Colore e forma:SolidPeso molecolare:456.52CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurezza:98.87%Colore e forma:SolidPeso molecolare:717.63CCT251545
CAS:CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).Formula:C23H24ClN5OPurezza:98.29% - 98.69%Colore e forma:SolidPeso molecolare:421.92TNIK-IN-5
CAS:TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formula:C22H17N3O3Purezza:99.58%Colore e forma:SolidPeso molecolare:371.39BML-286
CAS:BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.Formula:C22H18N2O4Purezza:98.44%Colore e forma:SolidPeso molecolare:374.39CCT 031374 hydrobromide
CAS:CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formula:C23H20BrN3OPurezza:99.50%Colore e forma:SolidPeso molecolare:434.33Ref: TM-T21685
1mg38,00€5mg71,00€10mg105,00€25mg207,00€50mg329,00€100mg472,00€200mg620,00€1mL*10mM (DMSO)87,00€NLS-StAx-h
Wnt inhibitor; halts cancer cell growth & spread by blocking β-catenin, IC50=1.4μM, cell-permeable.Formula:C161H275N55O29Purezza:98%Colore e forma:SolidPeso molecolare:3445.26β-catenin modulator IIa-661
CAS:β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.Formula:C19H23ClN2O3SPurezza:99.58%Colore e forma:SoildPeso molecolare:394.92Wnt/β-catenin agonist 3
CAS:Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.
Formula:C16H15ClN4O2Purezza:99.52%Colore e forma:SolidPeso molecolare:330.77ABC99
CAS:ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.Formula:C22H21ClN4O5Purezza:99.89%Colore e forma:SoildPeso molecolare:456.88Ref: TM-T23602
1mg114,00€2mg155,00€5mg222,00€10mg334,00€25mg595,00€50mg893,00€100mg1.243,00€200mg1.674,00€1mL*10mM (DMSO)224,00€Tabituximab
CAS:BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.Purezza:98.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 98.7% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.5 kDaFoxy-5 Ammonium Salt
Foxy-5 Ammonium Salt, a WNT5A mimetic, blocks epithelial cancer cell migration without β-catenin impact and curbs prostate cancer spread.Formula:C26H46N7O12S2Purezza:97.70%Colore e forma:SolidPeso molecolare:712.26Ref: TM-TP1565L1
1mg90,00€5mg288,00€10mg430,00€25mg705,00€50mg982,00€100mg1.324,00€1mL*10mM (DMSO)309,00€Foxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFormula:C26H42N6O12S2Purezza:98%Colore e forma:SolidPeso molecolare:694.771(R),2(S)-epoxy Cannabidiol
CAS:1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.Formula:C21H30O3Colore e forma:SolidPeso molecolare:330.46WIC1
CAS:2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.
Formula:C22H23N3O3Purezza:99.82%Colore e forma:SoildPeso molecolare:377.44Foxy-5 acetate
Foxy-5 acetate: Wnt 5A agonist, inhibits cancer cell migration/invasion, boosts calcium signaling, doesn't activate β-catenin.Formula:C28H46N6O14S2Purezza:98%Colore e forma:SolidPeso molecolare:754.83LP-922056
CAS:LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
Formula:C11H9ClN2O2S2Purezza:99.84%Colore e forma:SolidPeso molecolare:300.78YW2036
CAS:YW2036 is an inhibitor of Wnt signaling pathway.Formula:C20H16N4OPurezza:99.94%Colore e forma:SoildPeso molecolare:328.37F7H
CAS:F7H is an FZD7 antagonist, a potent ligand for the FZD7 transmembrane domain (TMD), with potential antitumor and bacteriostatic activities.
Formula:C24H18FN3O2S2Purezza:99.85%Colore e forma:SoildPeso molecolare:463.55
