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Cellule staminali

Cellule staminali

Gli inibitori delle cellule staminali sono composti che mirano specificamente alle cellule staminali e alle loro vie di segnalazione, influenzando la loro capacità di autorinnovarsi e differenziarsi. Questi inibitori sono cruciali nella ricerca focalizzata sul controllo del comportamento delle cellule staminali, sulla comprensione dei processi di sviluppo e sullo sviluppo di terapie per malattie come il cancro, dove si ritiene che le cellule staminali svolgano un ruolo chiave. Presso CymitQuimica, offriamo una varietà di inibitori delle cellule staminali per supportare la tua ricerca in medicina rigenerativa, biologia dello sviluppo e oncologia.

Trovati 467 prodotti di "Cellule staminali"

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  • ROCK-IN-8
    Targetmol
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    ROCK-IN-8

    CAS:
    ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,
    Formula:C30H25FN4O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:556.61

    Ref: TM-T79809

  • Casein kinase 1δ-IN-10
    Targetmol
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    Casein kinase 1δ-IN-10

    CAS:
    Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).
    Formula:C21H17N3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:359.38

    Ref: TM-T79697

  • STAT6-IN-2
    Targetmol
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    STAT6-IN-2

    CAS:
    STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.
    Formula:C28H31N5O2
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:469.58

    Ref: TM-T79185

  • ROCK-IN-1
    Targetmol
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    ROCK-IN-1

    CAS:
    <p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>
    Formula:C20H18FN3O
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:335.37

    Ref: TM-T13419

  • JAK-IN-3
    Targetmol
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    JAK-IN-3

    CAS:
    JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can be used for the study of immune system disorders.
    Formula:C18H20N4O3
    Purezza:98.04% - 98.19%
    Colore e forma:Solid
    Peso molecolare:340.38

    Ref: TM-T11704

  • H-1152 dihydrochloride
    Targetmol
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    H-1152 dihydrochloride

    CAS:
    H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.
    Formula:C16H23Cl2N3O2S
    Purezza:99.85%
    Colore e forma:Solid
    Peso molecolare:392.34

    Ref: TM-T35328

  • GNE-7883
    Targetmol
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    GNE-7883

    CAS:
    <p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>
    Formula:C28H29FN6O2
    Purezza:97.61%
    Colore e forma:Solid
    Peso molecolare:500.57

    Ref: TM-T78558

  • GSK-3 inhibitor 1
    Targetmol
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    GSK-3 inhibitor 1

    CAS:
    GSK-3 inhibitor 1 is a GSK-3 inhibitor.
    Formula:C22H17ClFN5O2
    Purezza:98.42%
    Colore e forma:Solid
    Peso molecolare:437.85

    Ref: TM-T11468

  • Carboxylesterase-IN-3
    Targetmol
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    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Formula:C11H6Cl2N4OS
    Purezza:97.49% - 98.47%
    Colore e forma:Solid
    Peso molecolare:313.16

    Ref: TM-T60788

  • MYF-03-176
    Targetmol
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    MYF-03-176

    CAS:
    <p>MYF-03-176 is an orally active TEAD1/3/4 inhibitor with IC₅₀ values of 47/32/71 nM. inhibits TEAD transcriptional activity and cancer cell growth, antitumour.</p>
    Formula:C19H18F4N4O2
    Colore e forma:Solid
    Peso molecolare:410.37

    Ref: TM-T62074

  • ROCK/HDAC-IN-1
    Targetmol
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    ROCK/HDAC-IN-1

    <p>ROCK/HDAC-IN-1 (Compound 10h) serves as an orally effective inhibitor of ROCK/HDAC. This compound suppresses ROCK1/2 (IC50: 254.9 nM, 58.18 nM) and HDAC1/2/3/6/8 (IC50: 9.09, 8.03, 6.26, 0.41, 7.69 nM). It stimulates the activation of DAMPs, notably calreticulin (CRT) exposure and HMGB1 release, suggesting its potential as an inducer of immunogenic cell death (ICD). ROCK/HDAC-IN-1 exhibits antiproliferative effects against breast cancer cells (IC50: 0.37 μM for MDA-MB-231 cells), inhibits tumor growth, activates T cells, and shows no significant toxicity.</p>
    Formula:C19H22N4O3S
    Colore e forma:Solid
    Peso molecolare:386.47

    Ref: TM-T201708

  • PMMB-187
    Targetmol
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    PMMB-187

    CAS:
    <p>PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.</p>
    Formula:C27H23BrN2O6S2
    Colore e forma:Solid
    Peso molecolare:615.52

    Ref: TM-T200126

  • STAT3-IN-8
    Targetmol
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    STAT3-IN-8

    CAS:
    <p>"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."</p>
    Formula:C19H7F7N2O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:444.26

    Ref: TM-T71550

  • JAK3 covalent inhibitor-1
    Targetmol
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    JAK3 covalent inhibitor-1

    CAS:
    JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM and
    Formula:C22H17FN6O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:448.47

    Ref: TM-T11709

  • STAT3-IN-36
    Targetmol
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    STAT3-IN-36

    CAS:
    <p>STAT3-IN-36 (compound 11g) is a tritarget inhibitor that selectively targets LRPPRC, STAT3, and CDK1, exhibiting potent anticancer activity. This compound binds to LRPPRC, STAT3, and CDK1, demonstrating more effective anticancer effects than those of TMF or Capecitabine. Additionally, STAT3-IN-36 exhibits an IC50 value of 1.8 μM in HGC27 cells.</p>
    Formula:C30H24F2N2O9S2
    Colore e forma:Solid
    Peso molecolare:658.65

    Ref: TM-T201706

  • JAK3-IN-7
    Targetmol
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    JAK3-IN-7

    CAS:
    <p>JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50&lt;0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after</p>
    Formula:C17H20N6O
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:324.38

    Ref: TM-T10009

  • GDC-9918
    Targetmol
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    GDC-9918

    CAS:
    <p>GDC-9918 (compound GDC-9918) is an inhibitor of Janus kinases.</p>
    Formula:C20H18F2N6O5S
    Colore e forma:Solid
    Peso molecolare:492.46

    Ref: TM-T201178

  • (+)-ITD-1
    Targetmol
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    (+)-ITD-1

    CAS:
    (+)-ITD-1 is an inhibitor of TGF-β, effectively inhibiting TGF-β2 with an IC50 of 0.46 μM. It promotes the degradation of the TGF-β type II receptor (TGFBR2) and the differentiation of cardiomyocytes. Additionally, it suppresses the formation of the mesoderm during the early differentiation of mouse embryonic stem cells (mESCs).
    Formula:C27H29NO3
    Colore e forma:Solid
    Peso molecolare:415.52

    Ref: TM-T201672

  • WZ-2-033
    Targetmol
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    WZ-2-033

    CAS:
    <p>WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 μM respectively.</p>
    Formula:C25H18F3N3O4S
    Colore e forma:Solid
    Peso molecolare:513.49

    Ref: TM-T200925

  • Casein kinase 1δ-IN-13
    Targetmol
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    Casein kinase 1δ-IN-13

    CAS:
    Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.
    Formula:C15H13N3O2S
    Colore e forma:Solid
    Peso molecolare:299.35

    Ref: TM-T201094