c-Kit
Gli inibitori di c-Kit sono composti che bloccano l'attività del Recettore del Fattore di Cella Staminale (c-Kit), una tirosina chinasi che svolge un ruolo cruciale nella sopravvivenza, proliferazione e differenziazione cellulare, in particolare nelle cellule ematopoietiche. Le mutazioni di c-Kit sono associate a vari tipi di cancro, tra cui i tumori stromali gastrointestinali (GIST) e la leucemia. Presso CymitQuimica, offriamo inibitori di c-Kit per supportare la tua ricerca in oncologia, ematologia e biologia delle cellule staminali.
Trovati 117 prodotti per "c-Kit".
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Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurezza:98.78% - 99.85%Colore e forma:SolidPeso molecolare:437.52Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formula:C30H35N7O4SPurezza:98% - >99.99%Colore e forma:White SolidPeso molecolare:589.71JI6
CAS:JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.Formula:C19H17N3O4SPurezza:99.09%Colore e forma:SoildPeso molecolare:383.421N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurezza:98.60%Colore e forma:SolidPeso molecolare:479.5762Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formula:C21H19ClN4O4Purezza:98.46% - 99.96%Colore e forma:White SolidPeso molecolare:426.85Regorafénib N-oxyde (M2)
CAS:Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.Formula:C21H15ClF4N4O4Purezza:98.03% - 98.26%Colore e forma:White SolidPeso molecolare:498.815Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formula:C22H18N4OSPurezza:98.9% - 99.74%Colore e forma:Off-White SolidPeso molecolare:386.47KG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).Formula:C20H16F3N7OSPurezza:98.32%Colore e forma:SolidPeso molecolare:459.45Anti-Human c-Kit Antibody (LMJ729)
Anti-c-Kit Antibody (LMJ729) is a human antibody, which is used in targeted delivery research.Purezza:97.0% (SDS-PAGE); 95.8% (SEC-HPLC) - 97.0% (SDS-PAGE); 95.8% (SEC-HPLC)Peso molecolare:145.93 kDa (Predicted)Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFormula:C22H23N5O·2H3PO4Purezza:99.69%Colore e forma:SolidPeso molecolare:569.44c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.Formula:C25H28FN5O5Colore e forma:SolidPeso molecolare:497.52Multi-kinase-IN-5
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,Formula:C19H15N5O2SColore e forma:SolidPeso molecolare:377.42AK177
AK177 is an allosteric activator of IRE1α ribonuclease, exhibiting binding affinities of 480 nM for non-phosphorylated and 180 nM for phosphorylated IRE1α. It promotes concentration-dependent cleavage of XBP1 mRNA probes by IRE1α and stably binds its kinase domain. However, AK177 displays poor kinase selectivity, and due to inadequate membrane permeability, shows negligible downstream pathway activation and antiproliferative activity at the cellular level.Amuvatinib hydrochloride
CAS:Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.Formula:C23H22ClN5O3SPurezza:98%Colore e forma:SolidPeso molecolare:483.97M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formula:C29H32N8OPurezza:99.07%Colore e forma:Yellow SolidPeso molecolare:508.6174Anti-C-Kit Antibody-FITC (8E724)
Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.Colore e forma:Odour LiquidAnti-C-Kit Antibody-PE (7P530)
Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.Colore e forma:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Colore e forma:Odour LiquidN-Desethyl Sunitinib-D5
CAS:N-Desethyl Sunitinib D5 is a deuterated compound of N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU012662) is the primary active metabolite of Sunitinib produced by the metabolism of cytochrome P450 enzyme 3A4 (CYP3A4).Sunitinib is an orally available inhibitor of a number of tyrosine kinases involved in tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3, and was approved for the treatment of advanced/metastatic renal cell carcinoma (RCC)Formula:C20H18D5FN4O2Peso molecolare:375.45Anti-C-Kit Antibody (1R766)
Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.Colore e forma:Odour Liquid
