c-Kit
Gli inibitori di c-Kit sono composti che bloccano l'attività del Recettore del Fattore di Cella Staminale (c-Kit), una tirosina chinasi che svolge un ruolo cruciale nella sopravvivenza, proliferazione e differenziazione cellulare, in particolare nelle cellule ematopoietiche. Le mutazioni di c-Kit sono associate a vari tipi di cancro, tra cui i tumori stromali gastrointestinali (GIST) e la leucemia. Presso CymitQuimica, offriamo inibitori di c-Kit per supportare la tua ricerca in oncologia, ematologia e biologia delle cellule staminali.
Trovati 116 prodotti per "c-Kit".
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OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:White SolidPeso molecolare:443.44Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formula:C29H34N6O4S2Purezza:97.67% - 98.44%Colore e forma:SolidPeso molecolare:594.75Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formula:C28H24FN3O5Purezza:99.68% - 99.88%Colore e forma:SolidPeso molecolare:501.51Flumatinib mesylate
CAS:Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formula:C30H33F3N8O4SPurezza:99.82%Colore e forma:SolidPeso molecolare:658.69Ref: TM-T7861
1mg34,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg126,00€25mg236,00€50mg371,00€100mg595,00€500mg1.234,00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purezza:99.97%Colore e forma:SolidPeso molecolare:537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purezza:97.08%Colore e forma:White SolidPeso molecolare:364.79Ref: TM-T22349
1mg38,00€5mg78,00€1mL*10mM (DMSO)84,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Formula:C19H21N3O2SPurezza:98.39%Colore e forma:White SolidPeso molecolare:355.45Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurezza:99.35% - 99.92%Colore e forma:SolidPeso molecolare:392.43Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurezza:98.9% - 99.85%Colore e forma:SolidPeso molecolare:629.68Ref: TM-T4349
5mg49,00€1mL*10mM (DMSO)69,00€10mg74,00€25mg130,00€50mg200,00€100mg319,00€200mg507,00€500mg800,00€Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formula:C29H29F3N8OPurezza:99.39% - 99.95%Colore e forma:White SolidPeso molecolare:562.59Ref: TM-T4320
1mg34,00€5mg63,00€10mg82,00€1mL*10mM (DMSO)82,00€25mg120,00€50mg155,00€100mg259,00€200mg388,00€500mg642,00€AZD3229 Tosylate
CAS:AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinalFormula:C31H34FN7O6SColore e forma:SolidPeso molecolare:651.71Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurezza:98.97% - 99.88%Colore e forma:SolidPeso molecolare:480.54Ref: TM-T4315
1mg44,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purezza:97.61% - >99.99%Colore e forma:SolidPeso molecolare:570.64Ref: TM-T3211
1mg49,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formula:C20H17F3N4O3Purezza:99.87%Colore e forma:SolidPeso molecolare:418.37Ref: TM-T4191
1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg101,00€25mg177,00€50mg268,00€100mg385,00€Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purezza:99.45% - ≥98%Colore e forma:SolidPeso molecolare:562.7Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formula:C23H25N7O2Purezza:99.05% - 99.57%Colore e forma:SolidPeso molecolare:431.49Ref: TM-T10652
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€SKLB4771
CAS:SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formula:C25H27N7O3S2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:537.66Ref: TM-T2051
1mg63,00€2mg93,00€5mg124,00€1mL*10mM (DMSO)148,00€10mg177,00€25mg371,00€50mg557,00€100mg792,00€500mg1.611,00€AZD3229
CAS:AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.Formula:C24H26FN7O3Purezza:98.83%Colore e forma:White SolidPeso molecolare:479.51Ref: TM-T5409
1mg42,00€5mg93,00€1mL*10mM (DMSO)94,00€10mg133,00€25mg235,00€50mg344,00€100mg482,00€200mg662,00€c-Kit-IN-1
CAS:c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formula:C26H21F2N5O3Purezza:98.72% - 98.73%Colore e forma:White SolidPeso molecolare:489.47Ref: TM-T4332
1mg37,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg224,00€50mg353,00€100mg578,00€200mg797,00€Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurezza:99.42% - 99.94%Colore e forma:SolidPeso molecolare:493.60
