Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formula:C17H20O5Purezza:99.61% - 99.72%Colore e forma:SolidPeso molecolare:304.34Ref: TM-TN6735
1mg92,00€5mg216,00€10mg283,00€25mg490,00€50mg700,00€100mg938,00€1mL*10mM (DMSO)215,00€Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formula:C19H26O7Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:366.41Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purezza:95.37% - 99.82%Colore e forma:Dark Green To Black SolidPeso molecolare:718.79Ref: TM-T3112
1mg40,00€2mg51,00€5mg85,00€10mg115,00€25mg225,00€50mg365,00€100mg462,00€1mL*10mM (DMSO)120,00€Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C24H29FN6·2CH4O3SPurezza:98% - 99.38%Colore e forma:SolidPeso molecolare:612.74Hydroxyprogesterone caproate
CAS:Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.Formula:C27H40O4Purezza:99.70%Colore e forma:White Or Almost White Crystalline PowerPeso molecolare:428.60Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurezza:98.89% - 99.28%Colore e forma:SolidPeso molecolare:265.25Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purezza:97.81% - 99.09%Colore e forma:SolidPeso molecolare:505.69BMS-582949 hydrochloride
CAS:The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).Formula:C22H27ClN6O2Purezza:97.57% - 98.75%Colore e forma:SolidPeso molecolare:442.95Ref: TM-T3462
1mg35,00€5mg71,00€10mg101,00€25mg170,00€50mg264,00€100mg393,00€200mg552,00€1mL*10mM (DMSO)78,00€Tazarotene
CAS:Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formula:C21H21NO2SPurezza:97.01% - 99.14%Colore e forma:White SolidPeso molecolare:351.46Ref: TM-T6696
5mg38,00€10mg49,00€25mg88,00€50mg147,00€100mg256,00€200mg334,00€500mg563,00€1mL*10mM (DMSO)55,00€Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purezza:96.39% - 99.29%Colore e forma:SolidPeso molecolare:394.42BIA 10-2474
CAS:BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formula:C16H20N4O2Purezza:99.27%Colore e forma:SolidPeso molecolare:300.36Pirarubicin
CAS:Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.Formula:C32H37NO12Purezza:97.80% - 99.15%Colore e forma:Red Crystalline PowderPeso molecolare:627.64kaempferide
CAS:kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formula:C16H12O6Purezza:98.4% - 99.66%Colore e forma:SolidPeso molecolare:300.26SR12813
CAS:SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Formula:C24H42O7P2Purezza:99.43%Colore e forma:SolidPeso molecolare:504.53GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formula:C21H27N7O3Purezza:98.07% - 99.77%Colore e forma:SolidPeso molecolare:425.48Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formula:C16H14F2N3NaO4SPurezza:96.92% - 99.81%Colore e forma:White To Off-White SolidPeso molecolare:405.35LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurezza:99.45%Colore e forma:SolidPeso molecolare:474.91Ref: TM-T4398
2mg37,00€5mg52,00€10mg84,00€25mg137,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)58,00€Cabergoline diphosphate
CAS:Cabergoline, a D2 receptor agonist, treats prolactinomas by normalizing prolactin levels.Formula:C26H43N5O10P2Colore e forma:SolidPeso molecolare:647.6PF-4708671
CAS:<p>PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).</p>Formula:C19H21F3N6Purezza:99.48% - 99.67%Colore e forma:SolidPeso molecolare:390.41Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purezza:95% - 99.19%Colore e forma:Yellow To Orange SolidPeso molecolare:383.83Ref: TM-T3419
2mg35,00€5mg52,00€10mg88,00€25mg154,00€50mg216,00€100mg305,00€200mg455,00€1mL*10mM (DMSO)Prezzo su richiestaBI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formula:C19H23F2N5O2Purezza:98.51% - 99.43%Colore e forma:SolidPeso molecolare:391.42VLX600
CAS:VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formula:C17H15N7Purezza:98.62%Colore e forma:SolidPeso molecolare:317.35Ganoderic acid A
CAS:Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formula:C30H44O7Purezza:99.31% - ≥95%Colore e forma:SolidPeso molecolare:516.67Ref: TM-T6S1141
1mg47,00€5mg97,00€10mg160,00€25mg250,00€50mg374,00€100mg547,00€1mL*10mM (DMSO)110,00€PAC-1
CAS:<p>PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.</p>Formula:C23H28N4O2Purezza:96.78% - 99.77%Colore e forma:SolidPeso molecolare:392.49Bromocriptine mesylate
CAS:Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)Formula:C33H44BrN5O8SPurezza:99.85% - 99.96%Colore e forma:White SolidPeso molecolare:750.7Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purezza:98.92% - 99.67%Colore e forma:White Crystal PowderPeso molecolare:608.72Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purezza:99.56% - >99.99%Colore e forma:SolidPeso molecolare:425.42Ref: TM-T6130
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg208,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€SR9011
CAS:SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).Formula:C23H31ClN4O3SPurezza:99.64% - 99.65%Colore e forma:SolidPeso molecolare:479.042-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purezza:98% - 99.95%Colore e forma:Off-White SolidPeso molecolare:302.41Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurezza:99.25% - >99.99%Colore e forma:SolidPeso molecolare:259.33Ref: TM-T1847
5mg35,00€10mg49,00€25mg82,00€50mg113,00€100mg170,00€200mg250,00€500mg419,00€1mL*10mM (DMSO)52,00€Fendiline
CAS:Fendiline: coronary vasodilator, calcium blocker, potential antiarrhythmic/antianginal.Formula:C23H25NColore e forma:SolidPeso molecolare:315.45DMOG
CAS:<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formula:C6H9NO5Purezza:80.23% - 99.98%Colore e forma:SolidPeso molecolare:175.14KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formula:C38H35N5O6S2Purezza:99.80% - >99.99%Colore e forma:White SolidPeso molecolare:721.84Ref: TM-T2694
1mg35,00€2mg52,00€5mg74,00€10mg111,00€25mg217,00€50mg425,00€100mg625,00€1mL*10mM (DMSO)111,00€Alirocumab
CAS:Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.Purezza:95% - 97.1% (SDS-PAGE); 96.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.2 kDaAdezmapimod
CAS:Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formula:C21H16FN3OSPurezza:99.42% - 99.93%Colore e forma:White SolidPeso molecolare:377.43Heparin sodium salt
CAS:Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Formula:C26H42N2NaO37S5Purezza:98%Colore e forma:SolidPeso molecolare:1157.89Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purezza:98.76% - >99.99%Colore e forma:SolidPeso molecolare:272.25Ref: TM-T6427
1mg43,00€2mg56,00€5mg88,00€10mg106,00€25mg213,00€50mg344,00€100mg550,00€1mL*10mM (DMSO)87,00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purezza:98.91% - 99.64%Colore e forma:White SolidPeso molecolare:453.50Gambogic Acid
CAS:Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.Formula:C38H44O8Purezza:97.16% - 98.67%Colore e forma:SolidPeso molecolare:628.75Ruxolitinib phosphate
CAS:<p>Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.</p>Formula:C17H21N6O4PPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:404.36Perifosine
CAS:Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formula:C25H52NO4PPurezza:99.80 - >99.99%Colore e forma:SolidPeso molecolare:461.66Atorvastatin strontium
CAS:Atorvastatin strontium lowers cholesterol, prevents heart disease, and treats dyslipidemia by inhibiting HMG-CoA reductase.Formula:C66H68F2N4O10SrColore e forma:SolidPeso molecolare:1202.9GANT 61
CAS:<p>GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.</p>Formula:C27H35N5Purezza:97.59% - >99.99%Colore e forma:SolidPeso molecolare:429.6UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purezza:99.82%Colore e forma:SolidPeso molecolare:436.58Ref: TM-T17209
1mg35,00€2mg52,00€5mg74,00€10mg119,00€25mg243,00€50mg406,00€100mg607,00€1mL*10mM (DMSO)86,00€Dansylcadaverine
CAS:Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.Formula:C17H25N3O2SPurezza:98.33% - 99.6%Colore e forma:SolidPeso molecolare:335.46Pemetrexed disodium hemipenta hydrate
CAS:<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Formula:C20H21N5O6·2NaH2OPurezza:98.76%Colore e forma:SolidPeso molecolare:518.43SD 0006
CAS:SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formula:C20H20ClN5O2Purezza:98.32%Colore e forma:SolidPeso molecolare:397.86Ref: TM-T7276
2mg38,00€5mg58,00€10mg90,00€25mg145,00€50mg226,00€100mg338,00€200mg472,00€1mL*10mM (DMSO)65,00€BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purezza:99.95%Colore e forma:SolidPeso molecolare:392.62Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purezza:95.10% - 99.3% （SEC-HPLC）Colore e forma:LiquidPeso molecolare:145 kDaDacinostat
CAS:LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.Formula:C22H25N3O3Purezza:95.28% - 97.88%Colore e forma:SolidPeso molecolare:379.45Ref: TM-T2454
1mg49,00€2mg67,00€5mg110,00€10mg180,00€25mg323,00€50mg487,00€100mg705,00€500mg1.444,00€1mL*10mM (DMSO)110,00€Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
Myristoylated autocamtide-2-related inhibitory peptide acetate is a cell-permeable CaM kinase II inhibitor.Formula:C80H146N22O22Purezza:97.03%Colore e forma:SolidPeso molecolare:1768.15Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purezza:99.4% - 99.8%Colore e forma:Light Yellow PowderPeso molecolare:312.45Ref: TM-T5574
1mg35,00€5mg52,00€10mg87,00€25mg160,00€50mg216,00€100mg305,00€200mg455,00€1mL*10mM (DMSO)58,00€SR-18292
CAS:SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.Formula:C23H30N2O2Purezza:99.16% - 99.91%Colore e forma:SolidPeso molecolare:366.5Ref: TM-T4353
2mg40,00€5mg60,00€10mg87,00€25mg180,00€50mg283,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)71,00€SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Formula:C19H20FN5OPurezza:99.13% - 99.68%Colore e forma:SolidPeso molecolare:353.39Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purezza:97.76% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:1030.29CA77.1
CAS:CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).Formula:C16H12ClN3OPurezza:99.50%Colore e forma:SolidPeso molecolare:297.74TOMATIDINE HYDROCHLORIDE
CAS:Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.Formula:C27H46ClNO2Purezza:99.75% - ≥95%Colore e forma:SolidPeso molecolare:452.11Triptonide
CAS:Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formula:C20H22O6Purezza:99.11% - 99.64%Colore e forma:White Crystalline PowderPeso molecolare:358.39Ref: TM-T5S1058
1mg56,00€2mgPrezzo su richiesta5mg114,00€10mg166,00€25mg283,00€50mg432,00€100mg628,00€200mg879,00€1mL*10mM (DMSO)140,00€Leonurine hydrochloride
CAS:Leonurine hydrochloride (SCM-198 hydrochloride) , a major alkaloid compound extracted from Leonurus japonicas Houtt.Formula:C14H22ClN3O5Purezza:99.07%Colore e forma:SolidPeso molecolare:347.79Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purezza:98.11% - 98.58%Colore e forma:SolidPeso molecolare:578.52palovarotene
CAS:<p>Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).</p>Formula:C27H30N2O2Purezza:97.88% - 98.05%Colore e forma:SolidPeso molecolare:414.54C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Formula:C24H19N3O6Purezza:98% - 99.21%Colore e forma:SolidPeso molecolare:445.42Ref: TM-T2452
2mg48,00€5mg69,00€10mg97,00€25mg195,00€50mg380,00€100mg562,00€500mg1.206,00€1mL*10mM (DMSO)69,00€SB 239063
CAS:<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Formula:C20H21FN4O2Purezza:99.42% - 99.81%Colore e forma:SolidPeso molecolare:368.4Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formula:C19H12ClN3O2Purezza:98% - 99.90%Colore e forma:SolidPeso molecolare:349.77Ref: TM-T2259
1mg40,00€2mg51,00€5mg85,00€10mg125,00€25mg207,00€50mg329,00€100mg520,00€500mg1.111,00€1mL*10mM (DMSO)93,00€Scriptaid
CAS:Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Formula:C18H18N2O4Purezza:96.74% - 99.45%Colore e forma:SolidPeso molecolare:326.35Ref: TM-T6980
5mg71,00€10mg97,00€25mg205,00€50mg378,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)79,00€4E1rcat
CAS:4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formula:C28H18N2O6Purezza:99.47%Colore e forma:SolidPeso molecolare:478.45Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purezza:97.169% - 99.59%Colore e forma:Dark Purple Crystalline PowderPeso molecolare:651.94β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Formula:C15H14O3Purezza:99.76% - 99.88%Colore e forma:SolidPeso molecolare:242.27DAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formula:C23H26F2N2O4Purezza:98.06% - 99.81%Colore e forma:White SolidPeso molecolare:432.46Ref: TM-T6202
2mg40,00€5mg58,00€10mg88,00€25mg165,00€50mg279,00€100mg378,00€200mg517,00€1mL*10mM (DMSO)59,00€Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Formula:C54H92O23Purezza:99.12% - 99.76%Colore e forma:SolidPeso molecolare:1109.29SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Formula:C13H10BrN3O4Purezza:98.16% - 99.85%Colore e forma:SolidPeso molecolare:352.14Ref: TM-T1955
5mg50,00€10mg66,00€25mg127,00€50mg225,00€100mg404,00€200mg617,00€500mg938,00€1mL*10mM (DMSO)52,00€FC131 TFA (606968-52-9 free base)
CAS:FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hivFormula:C38H48F3N11O8Purezza:99.39% - 99.67%Colore e forma:SolidPeso molecolare:843.85ATI-2341 acetate(1337878-62-2 free base)
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.Formula:C106H182N26O27S2Purezza:97.14%Colore e forma:SolidPeso molecolare:2316.87MSX-122
CAS:MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).Formula:C16H16N6Purezza:98.31% - 98.94%Colore e forma:SolidPeso molecolare:292.34Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormula:C16H12O5Purezza:96.26% - ≥95%Colore e forma:Pale-Yellow NeedlesPeso molecolare:284.26Danirixin
CAS:<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Formula:C19H21ClFN3O4SPurezza:99.78% - >99.99%Colore e forma:SolidPeso molecolare:441.9Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormula:C21H23N3O5Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:397.42Ref: TM-T7130
1mg40,00€5mg85,00€10mg120,00€25mg210,00€50mg316,00€100mg467,00€500mg1.026,00€1mL*10mM (DMSO)93,00€PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formula:C20H13FN4O2Purezza:98.65%Colore e forma:SolidPeso molecolare:360.34AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purezza:99.39%Colore e forma:SolidPeso molecolare:896.07SB-265610
CAS:SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.Formula:C14H9BrN6OPurezza:99.5%Colore e forma:SolidPeso molecolare:357.16Ref: TM-T16850
1mg56,00€5mg119,00€10mg187,00€25mg376,00€50mg560,00€100mg800,00€500mg1.644,00€1mL*10mM (DMSO)131,00€ML339
CAS:<p>ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.</p>Formula:C26H32ClN3O5Purezza:99.9%Colore e forma:SolidPeso molecolare:502AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formula:C21H28ClN5Purezza:98.38% - 98.57%Colore e forma:SolidPeso molecolare:385.93CTCE 9908 acetate
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.Formula:C88H151N27O25Purezza:98.47%Colore e forma:SolidPeso molecolare:1987.31MSX-127
CAS:MSX-127 elicites positive response in peptide CXCR4.Formula:C16H24N2O4Purezza:98.43%Colore e forma:SolidPeso molecolare:308.37WZ811
CAS:WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).Formula:C18H18N4Purezza:99.42% - ≥95%Colore e forma:SolidPeso molecolare:290.36USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurezza:98.46% - 99.56%Colore e forma:SolidPeso molecolare:422.57Ref: TM-T17208
1mg42,00€5mg88,00€10mg127,00€25mg250,00€50mg393,00€100mg628,00€500mg1.304,00€1mL*10mM (DMSO)87,00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purezza:99.21%Colore e forma:SolidPeso molecolare:531.13Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purezza:98% - 99.5%Colore e forma:SolidPeso molecolare:855.02JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Formula:C25H26ClN3OPurezza:98.7% - 99.44%Colore e forma:SolidPeso molecolare:419.95Ref: TM-T5849
1mg38,00€5mg82,00€10mg124,00€25mg210,00€50mg328,00€100mg485,00€200mg702,00€1mL*10mM (DMSO)92,00€TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.Formula:C92H144N34O21S2Purezza:98.33% - 99.71%Colore e forma:SolidPeso molecolare:2126.47MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Formula:C36H26N4Purezza:99.19%Colore e forma:SolidPeso molecolare:514.62SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purezza:99.65% - 99.92%Colore e forma:SolidPeso molecolare:475.53Plerixafor
CAS:Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.Formula:C28H54N8Purezza:99.17% - >99.99%Colore e forma:SolidPeso molecolare:502.78AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Formula:C18H22F2N4O5S2Purezza:98.38% - 98.63%Colore e forma:SolidPeso molecolare:476.52Ref: TM-T7681
1mg37,00€2mg49,00€5mg70,00€10mg103,00€25mg202,00€50mg311,00€100mg472,00€200mgPrezzo su richiesta1mL*10mM (DMSO)78,00€Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Formula:C28H62Cl8N8Purezza:98.01% - 99.79%Colore e forma:SolidPeso molecolare:794.46SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurezza:98.19% - 99.61%Colore e forma:SolidPeso molecolare:467.2Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Formula:C20H20O4Purezza:98% - 99.76%Colore e forma:SolidPeso molecolare:324.37HG-10-102-01
CAS:HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Formula:C17H20ClN5O3Purezza:99.59%Colore e forma:SolidPeso molecolare:377.83Ref: TM-T7196
2mg38,00€5mg58,00€10mg94,00€25mg170,00€50mg264,00€100mg380,00€200mg540,00€1mL*10mM (DMSO)65,00€Lucanthone
CAS:Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formula:C20H24N2OSPurezza:99.92%Colore e forma:Yellow Crystals From Alcohol SolidPeso molecolare:340.48Ref: TM-T4569
1mg56,00€2mg80,00€5mg126,00€10mg188,00€25mg400,00€50mg592,00€100mg837,00€1mL*10mM (DMSO)140,00€Pennogenin 3-O-β-chacotrioside
CAS:Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.Formula:C45H72O17Purezza:99.69% - 99.77%Colore e forma:SolidPeso molecolare:885.04Ref: TM-T8166
1mg65,00€5mg127,00€10mg188,00€25mg321,00€50mg470,00€100mg698,00€1mL*10mM (DMSO)Prezzo su richiesta
