Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1495 prodotti di "Autofagia"
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PBA-1105 TFA
PBA-1105 TFA is an autophagy-targeting chimera (AUTOTAC) that induces p62 self-oligomerization. This compound selectively binds to the exposed hydrophobic regions of misfolded proteins, promoting their degradation through the autophagy (autophagy) pathway. Additionally, PBA-1105 TFA enhances the autophagic flux of Ub-bound aggregates.Formula:C41H49F3N2O8Colore e forma:SolidPeso molecolare:754.832N-Desmethyl rosuvastatin disodium hydrate
N-Desmethyl rosuvastatin disodium hydrate is an active metabolite of rosuvastatin, a HMG-CoA reductase (HMGCR) inhibitor. It is utilized in research pertaining to the metabolism of rosuvastatin.Colore e forma:Odour SolidTRAF6 peptide
CAS:TRAF6 peptide inhibits TRAF6-p62, blocks TrkA ubiquitination, and shows promise for neurological disease research.Formula:C145H238N34O44Colore e forma:SolidPeso molecolare:3161.64Hexidium iodide
CAS:Hexidium iodide fluoresces, stains mammalian cells & gram-positive bacteria, and binds to DNA with EDTA. Excitation/emission: ~518/600 nm.Formula:C25H28IN3Colore e forma:SolidPeso molecolare:497.424Valproic acid sodium salt
CAS:Sodium valproate is an anti-epileptic, boosting brain GABA levels and possibly affecting potassium channels for membrane stability.Formula:C8H15NaO2Purezza:98% - 99.78%Colore e forma:White PowderPeso molecolare:166.2SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Formula:C22H26N4O5Colore e forma:SolidPeso molecolare:426.47Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurezza:99.79% - 99.84%Colore e forma:SolidPeso molecolare:291.37MW-150 hydrochloride
CAS:MW-150 hydrochloride is a selective p38α MAPK inhibitor with a 101 nM Ki, offering good CNS penetration and oral bioavailability.Formula:C24H24ClN5Colore e forma:SolidPeso molecolare:417.93Polyphemusin II-Derived Peptide
CAS:T140, a Polyphemusin II-derived peptide, inhibits HIV-1 entry and blocks anti-CXCR4 antibody (12G5) binding.Formula:C90H141N33O18S2Colore e forma:SolidPeso molecolare:2037.42Peptide 78
CAS:Peptide 78 is identical to peptide 74 except that serine replaces cysteine. It does not inhibit 72-kDa type IV collagenase.Formula:C62H107N23O21SPurezza:98%Colore e forma:SolidPeso molecolare:1542.74Anticancer agent 161
Compound 3b, known as Anticancer Agent 161, is a bioactive alkynol exhibiting potential anticancer properties.Colore e forma:Odour SolidClionamine B
CAS:Clionamine B, an aminosteroid from Cliona celata, enhances autophagy in MCF-7 breast cancer cells.Formula:C27H45NO3Colore e forma:SolidPeso molecolare:431.65ML-SA5
CAS:ML-SA5 is a MCOLN1 agonist that blocks autophagic flux by disrupting fusion between autophagosomes and lysosomes.Cost-effective and quality-assured.
Formula:C19H24ClN3O4S2Purezza:99.16% - >99.99%Colore e forma:SoildPeso molecolare:457.99HuMax-IL8
HuMax-IL8 (MDX 018) is a humanized anti-IL-8 monoclonal antibody for the study of metastatic or unresectable solid tumors.Purezza:98.8% (SDS-PAGE); 97.4% (SEC-HPLC) - 98.8% (SDS-PAGE); 97.4% (SEC-HPLC)Colore e forma:Odour LiquidRimantadine
CAS:Rimantadine (1-Rimantadine) (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.Formula:C12H21NPurezza:98%Colore e forma:SolidPeso molecolare:179.3PROTAC EGFR degrader 4
CAS:PROTAC EGFR degrader 4 targets mutant EGFR, degrades del19 and L858R/T790M (DC50: 0.51, 126 nM), and inhibits HCC827, H1975 cell growth (IC50: 0.83, 203.1 nM).Formula:C55H70N12O4SColore e forma:SolidPeso molecolare:995.29JH-XII-03-02
CAS:JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PDFormula:C43H51N9O10Purezza:98%Colore e forma:SolidPeso molecolare:853.92Basic Blue 20
CAS:Basic Blue 20: Red-emitting DNA stain, peaks at 633/677 nm, high photobleaching resistance.Formula:C26H33Cl2N3Colore e forma:SolidPeso molecolare:458.47Retinoic acid-d5
CAS:Retinoic acid-d5: deuterium-labeled, natural RAR agonist (IC50: 14 nM), affects cell growth and development, inhibits Nrf2.Formula:C20H28O2Purezza:98%Colore e forma:SoildPeso molecolare:305.47Peptide R
CAS:Peptide R, a cyclic CXCR4 antagonist, remodels tumor stroma, aiding cancer research.Formula:C39H59N13O8S2Colore e forma:SolidPeso molecolare:902.1Diquat dibromide
CAS:Diquat dibromide is a water-soluble herbicide that causes rapid and profound systemic toxicity.Diquat dibromide induces acute kidney injury with high lethality.Formula:C12H12Br2N2Purezza:97.11% - 99%Colore e forma:SolidPeso molecolare:344.05TH152
CAS:TH152 is a general reversible ligand for LC3/GABARAP with a dissociation constant (KD) of 2 µM. LC3/GABARAP is a protein associated with autophagy.Formula:C22H23ClN4O4S2Colore e forma:SolidPeso molecolare:507.03Mito-fisetin mF3
Mito-fisetin mF3 (compund mito-fisetin mF3) is a potent anticancer and anti-aging therapeutic agent that targets mitochondria.Formula:C52H42IO7PColore e forma:SolidPeso molecolare:936.76Erlotinib-13C6
CAS:Erlotinib-13C6 (CP-358774-13C6), a 13C-labeled direct EGFR inhibitor, IC50: 2 nM.Formula:C22H23N3O4Colore e forma:SolidPeso molecolare:399.397OsMo
OsMo is a lysosomal-targeting hNEU1 inhibitor utilized in the study of myocardial injury.Colore e forma:Odour SolidTC14012
CAS:CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).Formula:C90H140N34O19S2Purezza:98%Colore e forma:SolidPeso molecolare:2066.43Acridine homodimer
CAS:Acridine homodimer (NSC 219743), a blue-green fluorescent dye, binds DNA, preferring AT-rich areas, useful for chromosome banding.Formula:C38H42Cl2N6O2Colore e forma:SolidPeso molecolare:685.69PTX80
CAS:PTX80 is an antagonist of p62, with an IC50 value of 31.18 nM. It has been shown to reduce tumor volume in a HCT116 colorectal cancer mouse xenograft model.Formula:C26H26N4O3SColore e forma:SolidPeso molecolare:474.58PIK5-12d
PIK5-12d, a potent PROTAC PIKfyve degrader (DC50: 1.48 nM), effectively induces cytoplasmic vacuolization and inhibits autophagic flux in various prostateFormula:C52H64N10O7SPurezza:99.90%Colore e forma:SolidPeso molecolare:973.19Autocamtide 2, amide
Autocamtide-2, an amide, is a selective CaMKII substrate for CAMK family assays at 100 μM.Formula:C65H119N23O19Purezza:98%Colore e forma:SolidPeso molecolare:1526.79BVT173187
CAS:BVT173187 is a neutrophil formyl peptide receptors (FPR1) inhibitor.Formula:C14H10Cl3NO2Colore e forma:SolidPeso molecolare:330.59Hoechst 33342 analog trihydrochloride
CAS:Hoechst 33342 analog trihydrochloride, an analog of Hoechst 33342, serves as a fluorochrome by binding to the minor groove of DNA, facilitating theFormula:C32H38Cl3N7Colore e forma:SolidPeso molecolare:627.05MeCY5-NHS ester triethylamine
MeCY5-NHS ester (potassium) is a reactive dye optimized for labeling proteins and nucleic acids [1].Formula:C42H56N4O10S2Colore e forma:SolidPeso molecolare:841.04PDEδ autophagic degrader 1
PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.Formula:C41H42Br2IN7O5Peso molecolare:997.06589CX4338
CAS:CX4338 is a CXCL8-mediated chemotaxis inhibitor.Formula:C22H24N2OSColore e forma:SolidPeso molecolare:364.50Autophagy/REV-ERB-IN-1 hydrochloride
Autophagy/REV-ERB-IN-1 hydrochloride (Compound 24) is a dual inhibitor of autophagy and REV-ERB with anticancer properties. It enhances the efficacy of autophagy blockade and increases cytotoxicity against cancer cells. Autophagy/REV-ERB-IN-1 (hydrochloride) is applicable in melanoma research.Formula:C24H32Cl2F2N2Peso molecolare:456.19106(3R,5S)-Fluvastatin
CAS:(3R,5S)-Fluvastatin, a synthetic HMG-CoA reductase inhibitor (IC50: 8 nM), activates Nrf2 for antioxidant defense.Formula:C24H26FNO4Colore e forma:SolidPeso molecolare:411.47(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding linker. This compound serves as a Cereblon ligand to recruit CRBN protein and acts as a crucial intermediate in the synthesis of complete PROTAC molecules.Formula:C31H41N5O6Peso molecolare:579.30568cGMP-HTL
cGMP-HTL, an AUTAC, promotes K63-linked mitochondrial ubiquitination with a Cys-S-cGMP tag and target-specific warhead.Formula:C31H51ClN7O14PSColore e forma:SolidPeso molecolare:844.27(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), consisting of Thalidomide and the corresponding Linker. It functions as a Cereblon ligand to recruit the CRBN protein and serves as a crucial intermediate for synthesizing complete PROTAC molecules.
Formula:C27H32N8O5Peso molecolare:548.24957NI-0801
NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.Purezza:97.9% (SDS-PAGE); 99.4% (SEC-HPLC) - 97.9% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:144.81 kDaMRT67307
CAS:Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formula:C26H36N6O2Purezza:99.25% - 99.84%Colore e forma:SolidPeso molecolare:464.6Tetramethylrhodamine-dUTP
Tetramethylrhodamine-dUTP (TAMRA-dUTP) is used for end-labeling of DNA [1] .Formula:C43H52N6O19P3Colore e forma:SolidPeso molecolare:1049.82(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate combining an E3 ligase ligand with a linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding Linker. This compound functions as a Cereblon ligand, recruiting the CRBN protein and serving as a crucial intermediate in the synthesis of complete PROTAC molecules.Formula:C29H36N8O6Peso molecolare:592.27578PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withColore e forma:Odour SolidRef: TM-L1300
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaCXCL8 (54-72)
CXCL8 (54-72) is a C-terminal peptide segment of the chemokine CXCL8. This peptide features a long, highly positively charged C-terminal region that interacts with the negative charges on glycosaminoglycans (GAG) to facilitate binding. CXCL8 (54-72) inhibits neutrophil adhesion and migration, as well as adhesion to endothelial cells. It is useful in studying the role of chemokines in inflammatory responses.Formula:C107H173N33O30Peso molecolare:2400.30261Autophagy/REV-ERB-IN-1
Autophagy/REV-ERB-IN-1 is a dual inhibitor of autophagy and REV-ERB. It exhibits antitumor activity, with a CC50 value of 2.3 μM in BTB-474 cells.Formula:C24H30F2N2Peso molecolare:384.23771(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-CH2-COO-C(CH3)3
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-CH2-COO-C(CH3)3 is an E3 ligase ligand-linker conjugate (E3LigaseLigand-Linker Conjugates) composed of thalidomide and its corresponding linker. This compound functions as a Cereblon ligand, facilitating the recruitment of CRBN protein, and serves as a crucial intermediate in the synthesis of complete PROTAC molecules.Formula:C33H42N8O7Peso molecolare:662.31765CCR7 antagonist 1
CCR7 antagonist1 (30c) functions as a dual antagonist, targeting CXCR2 with an IC50 of 11.02 μM and CCR7 with an IC50 of 0.43 μM.Formula:C13H22N6OSPeso molecolare:310.15758Antitumor agent-133
Antitumor agent-133 (compound 4d) is a bis-santine derivative that demonstrates activity against Huh1 (IC50 = 17.13 μM) and Huh7 (IC50 = 8.27 μM). It induces autophagy and inhibits tumor growth by modulating the levels of the LC3BII, ATG5, and p62 proteins.Formula:C27H24Br2N4O8Peso molecolare:689.99609CXCR4-IN-3
CXCR4-IN-3 (compound XVI) is an orally active inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. It exhibits potent anti-chemotactic effects, with an inhibition rate of 79.19±2.33%. Additionally, CXCR4-IN-3 possesses anti-inflammatory properties and can be utilized in research on IBD (inflammatory bowel disease).
Bam 12P
CAS:Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.Formula:C62H97N21O16SPurezza:98%Colore e forma:SolidPeso molecolare:1424.64Ch55-O-C3-NH2
CAS:Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR.Formula:C27H35NO4Purezza:98%Colore e forma:SolidPeso molecolare:437.57(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc
(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding linker. It acts as a Cereblon ligand, recruiting CRBN proteins, and serves as a crucial intermediate in the synthesis of complete PROTAC molecules.
Formula:C30H39N5O6Peso molecolare:565.29003RCP168
RCP168 is a highly selective and potent CXCR4 receptor antagonist with an IC50 of 5 nM. It exhibits superior capacity to inhibit HIV-1 (Human Immunodeficiency Virus type 1) from entering host cells via the CXCR4 receptor compared to natural chemokines. RCP168 suppresses HIV-1 infection by blocking viral binding sites or inducing receptor internalization. It can be utilized in research to study interactions between the CXCR4 receptor and other chemokine receptors.Formula:C365H585N105O95S5Peso molecolare:8119.27766KN-93 hydrochloride
CAS:KN-93 hydrochloride is a reversible, competitive CaMKII inhibitor inducing reversible G1 arrest, supporting cell cycle and signaling pathway studies.Formula:C26H30Cl2N2O4SPurezza:99.99%Colore e forma:SolidPeso molecolare:537.5Pyrazinamide-d3
CAS:Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.Formula:C5D3H2N3OColore e forma:SolidPeso molecolare:126.13Dexamethasone-d5
CAS:Dexamethasone-d5 is a deuterated compound of Dexamethasone.Formula:C22H24D5FO5Colore e forma:SolidPeso molecolare:397.49Olaparib-d5
CAS:Olaparib D5 is a deuterium labeled Olaparib. Olaparib is a potent and oral inhibitor of PARP.Formula:C24H23FN4O3Purezza:98%Colore e forma:SolidPeso molecolare:439.49Imatinib D4
CAS:Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.Formula:C29H31N7OPurezza:98%Colore e forma:SolidPeso molecolare:497.63Bexarotene D4
CAS:Bexarotene D4 is a deuterium-labeled Bexarotene (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma.Formula:C24H28O2Purezza:98%Colore e forma:SolidPeso molecolare:352.5Trimetazidine
CAS:Trimetazidine is a antianginal agent that selectively inhibits the mitochondrial enzyme LC 3-KAT, thereby preventing β-oxidation of free fatty acids.Formula:C14H22N2O3Purezza:99.9%Colore e forma:Hite Or Off-White Crystalline PowderPeso molecolare:266.34Binimetinib-13C-d3
Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.
Formula:C17H15BrF2N4O3Colore e forma:SolidPeso molecolare:445.24LG100268
CAS:LG100268 is a selective, and oral RXR agonist，inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.Formula:C24H29NO2Purezza:99.83%Colore e forma:SolidPeso molecolare:363.49Enzalutamide-d3
CAS:Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.Formula:C21H16F4N4O2SColore e forma:SolidPeso molecolare:467.45TRAF6 peptide TFA
TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.Formula:C145H238N34O44·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:3161.64 (free acid)Isoniazid-d4
CAS:Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.Formula:C6H3D4N3OColore e forma:SolidPeso molecolare:141.16Rapalink-1
CAS:Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.Formula:C91H138N12O24Purezza:98%Colore e forma:SolidPeso molecolare:1784.14Gemcitabine elaidate
CAS:Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, withFormula:C27H43F2N3O5Colore e forma:SolidPeso molecolare:527.64Erlotinib-d6 hydrochloride
CAS:Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Formula:C22H24ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:435.93Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formula:C29H41F3N8O9Colore e forma:SolidPeso molecolare:702.68Saquinavir mesylate
CAS:Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapyFormula:C39H54N6O8SPurezza:99.19%Colore e forma:White Or Pale Yellow PowderPeso molecolare:766.9Ponatinib-d8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formula:C29H27F3N6OPurezza:98%Colore e forma:SolidPeso molecolare:540.61GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purezza:98%Colore e forma:SolidPeso molecolare:400.21Rosuvastatin D3 Sodium
CAS:Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).Formula:C22H24D3FN3NaO6SPurezza:98%Colore e forma:SolidPeso molecolare:506.54R1487 Hydrochloride
CAS:R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.Formula:C19H19ClF2N4O3Purezza:99.42%Colore e forma:SolidPeso molecolare:424.83Anti-LRRK2 Antibody (1C773)
Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.Colore e forma:Odour LiquidTetrahydrocurcumin D6
CAS:Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.Formula:C21H24O6Purezza:98%Colore e forma:SolidPeso molecolare:378.45PS372424 hydrochloride
CAS:PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Formula:C33H45ClN6O4Purezza:95.03%Colore e forma:SolidPeso molecolare:625.2Manzamine A
CAS:Manzamine A, from marine sponges, blocks GSK-3, halts cancer growth, prevents bacterial infections, and reduces tau phosphorylation.Formula:C36H44N4OPurezza:98%Colore e forma:SolidPeso molecolare:548.775Idelalisib D5
CAS:Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.Formula:C22H18FN7OPurezza:98%Colore e forma:SolidPeso molecolare:420.45Ladarixin
CAS:Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis.Formula:C11H12F3NO6S2Purezza:99.36%Colore e forma:SolidPeso molecolare:375.34Ezetimibe-d4
CAS:Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activationFormula:C24H21F2NO3Purezza:98%Colore e forma:White SolidPeso molecolare:413.45Curcumin-d6
CAS:Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-aFormula:C21H20O6Purezza:98%Colore e forma:SolidPeso molecolare:374.422THZ-P1-2
CAS:THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study of leukemia.Formula:C31H29N7O2Colore e forma:SolidPeso molecolare:531.61Ref: TM-T39459
1mg74,00€2mgPrezzo su richiesta5mg160,00€10mg216,00€25mg349,00€50mg494,00€100mg692,00€200mg934,00€1mL*10mM (DMSO)182,00€Br-DAPI
CAS:IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.Formula:C16H14BrN5Purezza:100%Colore e forma:SolidPeso molecolare:356.22V-9302 hydrochloride
CAS:V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.Formula:C34H39ClN2O4Purezza:97.31%Colore e forma:SolidPeso molecolare:575.14Omeprazole-d3
CAS:Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)Formula:C17H19N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:348.44OR-1855
CAS:OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.Formula:C11H13N3OPurezza:98%Colore e forma:Pale Yellow SolidPeso molecolare:203.24Aliskiren
CAS:Aliskiren (CGP 60536) is a renin inhibitor (IC50: 1.5 nM) with antihypertensive activity and is used in the treatment of various cardiovascular diseases.Formula:C30H53N3O6Purezza:97.02%Colore e forma:SolidPeso molecolare:551.76Ref: TM-T22233
1mg35,00€5mg73,00€10mg105,00€25mg149,00€50mg187,00€100mg283,00€200mg419,00€1mL*10mM (DMSO)89,00€ACT-1004-1239
CAS:ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.
Formula:C27H28F2N6O3Purezza:98.31%Colore e forma:SolidPeso molecolare:522.55Motixafortide
CAS:Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).Formula:C97H144FN33O19S2Purezza:98%Colore e forma:SolidPeso molecolare:2159.52ATI-2341
CAS:ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Formula:C104H178N26O25S2Colore e forma:SolidPeso molecolare:2256.82Heparin Lithium
CAS:Heparin Lithium salt is an anticoagulant that reversibly binds to ATIII and enhances its inhibitory effect on coagulation factor(thrombin and factor Xa).Formula:C14H25NO20S3Colore e forma:SolidPeso molecolare:623.01321(R)-BPO-27
CAS:(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.Formula:C26H18BrN3O6Purezza:99.1%Colore e forma:SolidPeso molecolare:548.34CXCR2 antagonist 8
CAS:CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.Formula:C14H13N3O5Colore e forma:SolidPeso molecolare:303.27IKK 16 hydrochloride
CAS:IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.Formula:C28H30ClN5OSColore e forma:SolidPeso molecolare:520.09Ambroxol hydrochloride (Standard)
CAS:Ambroxol hydrochloride (Standard) is the standard substance of Ambroxol hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.Formula:C13H18Br2N2O·HClPeso molecolare:414.56Desethyl chloroquine diphosphate
CAS:Desethyl chloroquine diphosphate is the active metabolite of Desethylchloroquine, an inhibitor of TLRs with antiplasmodial activity and inhibition of autophagy.Formula:C16H28ClN3O8P2Purezza:99.72%Colore e forma:SolidPeso molecolare:487.81Levomepromazine
CAS:Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.Formula:C19H24N2OSPurezza:99.15%Colore e forma:SolidPeso molecolare:328.47Cediranib maleate
CAS:Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Formula:C29H31FN4O7Colore e forma:SolidPeso molecolare:566.58Ref: TM-T2500L
5mg205,00€10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)225,00€Resveratrol analog 1
CAS:Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.Formula:C14H11FO2Purezza:98.42%Colore e forma:SolidPeso molecolare:230.23Theophylline-d6
CAS:Theophylline-d6, an internal standard for theophylline quantification in GC/LC-MS, relaxes bronchial muscles and treats asthma/COPD.Formula:C7H2D6N4O2Colore e forma:SolidPeso molecolare:186.2Imatinib-d8
CAS:Imatinib-d8 (STI571 D8) is a 2H-labeled form of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with antitumor activity.Formula:C29H23D8N7OPurezza:98%Colore e forma:SolidPeso molecolare:501.65Rupatadine
CAS:Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.Formula:C26H26ClN3Purezza:99.87%Colore e forma:SolidPeso molecolare:415.96Megestrol Acetate-d3
CAS:Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.Formula:C24H29D3O4Colore e forma:SolidPeso molecolare:387.53Pazopanib-d6
CAS:Pazopanib-d6 is a deuterated compound of Pazopanib.Formula:C21H17D6N7O2SColore e forma:SolidPeso molecolare:443.56Rapamycin-d3
CAS:Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).Formula:C51H79NO13Purezza:98%Colore e forma:SolidPeso molecolare:917.19Venetoclax-d8
CAS:Venetoclax-d8 (ABT-199-d8) is a deuterated form of Venetoclax, a potent, selective, and orally active Bcl-2 inhibitor that induces autophagy and apoptosis.Formula:C45H42D8ClN7O7SColore e forma:SolidPeso molecolare:876.49Nilotinib-d6
CAS:Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.Formula:C28H22F3N7OPurezza:98%Colore e forma:SolidPeso molecolare:535.55Afatinib D6
CAS:Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.Formula:C24H25ClFN5O3Colore e forma:SolidPeso molecolare:491.98LY2510924
CAS:LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).Formula:C62H88N14O10Colore e forma:SolidPeso molecolare:1189.45Peptide R TFA
Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.
Formula:C39H57N13O8S2·xC2HF3O2Colore e forma:SolidPeso molecolare:900.08 (free base)Gefitinib-d8
CAS:Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.Formula:C22H24ClFN4O3Purezza:98%Colore e forma:SolidPeso molecolare:454.95Silibinin-d3
Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.Formula:C25H22O10Colore e forma:SolidPeso molecolare:485.46Brivanib
CAS:Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormula:C19H19FN4O3Purezza:98.87%Colore e forma:SolidPeso molecolare:370.38Ref: TM-T6036
1mg47,00€5mg88,00€10mg144,00€25mg259,00€50mg375,00€100mg560,00€200mg815,00€1mL*10mM (DMSO)97,00€Regorafenib-d3
CAS:Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Formula:C21H15ClF4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:485.83Loperamide-d6 hydrochloride
CAS:Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.Formula:C29H34Cl2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:519.54Pemetrexed disodium heptahydrate
CAS:Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.Formula:C20H33N5Na2O13Purezza:99.783%Colore e forma:SolidPeso molecolare:597.49Vancomycin hydrochloride (Standard)
CAS:Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.Formula:C66H76Cl3N9O24Colore e forma:Off White PowderPeso molecolare:1485.71Thiacloprid
CAS:Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.Formula:C10H9ClN4SPurezza:98.66% - 99.95%Colore e forma:Yellowish Crystalline PowderPeso molecolare:252.72Isorhapontigenin
CAS:Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.Formula:C15H14O4Purezza:98.49% - 99.85%Colore e forma:Off White Crystals PowerPeso molecolare:258.27Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purezza:97.78% - 99%Colore e forma:Colourless To Pale Yellow Liquid ViscousPeso molecolare:144.21Ginkgolide K
CAS:Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.Formula:C20H22O9Purezza:99.44% - 99.72%Colore e forma:SolidPeso molecolare:406.38Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purezza:99.04% - 99.3%Colore e forma:SolidPeso molecolare:785.01Ref: TM-T3916
1mg35,00€5mg69,00€10mg88,00€25mg144,00€50mg205,00€100mg303,00€500mg735,00€1mL*10mM (DMSO)97,00€Momelotinib
CAS:Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formula:C23H22N6O2Purezza:97.07% - 99.56%Colore e forma:SolidPeso molecolare:414.46Ref: TM-T1849
1mg38,00€2mg49,00€5mg81,00€10mg95,00€25mg166,00€50mg259,00€100mg406,00€200mg625,00€1mL*10mM (DMSO)88,00€Clematichinenoside AR
CAS:Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Formula:C82H134O43Purezza:99.04% - 99.69%Colore e forma:SolidPeso molecolare:1807.92Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Formula:C31H43N3O8Purezza:98.24% - 99.83%Colore e forma:Dark Purple SolidPeso molecolare:585.69Lapatinib tosylate
CAS:Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Formula:C36H34ClFN4O7S2Colore e forma:SolidPeso molecolare:753.26TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purezza:99.17% - 99.53%Colore e forma:White Solid PowderPeso molecolare:166.22Selenomethionine
CAS:DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.Formula:C5H11NO2SePurezza:98% - 99.95%Colore e forma:Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidPeso molecolare:196.11Dimethyl fumarate
CAS:Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H8O4Purezza:90.51% - >99.99%Colore e forma:White To Off-White Powder White Crystalline PowderPeso molecolare:144.13JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Formula:C25H27Cl2N3OColore e forma:SolidPeso molecolare:456.41GNE0877
CAS:GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Formula:C14H16F3N7Purezza:98.01% - 99.97%Colore e forma:SolidPeso molecolare:339.32Ref: TM-T6031
1mg44,00€2mg57,00€5mg113,00€10mg177,00€25mg356,00€50mg532,00€100mg760,00€500mg1.558,00€1mL*10mM (DMSO)90,00€Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFormula:C14H11ClN6O3Purezza:99.25% - 99.41%Colore e forma:SolidPeso molecolare:346.73Ref: TM-T4219
2mg39,00€5mg58,00€10mg88,00€25mg160,00€50mg215,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)66,00€STO-609
CAS:STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.
Formula:C19H10N2O3Purezza:97.14% - 98.8%Colore e forma:SolidPeso molecolare:314.29Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purezza:96.83% - 99.93%Colore e forma:SolidPeso molecolare:384.47ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurezza:98.84% - 99.50%Colore e forma:SolidPeso molecolare:371.41FIPI HCl
CAS:FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.Formula:C23H25ClFN5O2Colore e forma:SolidPeso molecolare:457.93Clinofibrate
CAS:Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formula:C28H36O6Purezza:>99.99%Colore e forma:White Crystalline PowderPeso molecolare:468.58Alginic acid
CAS:Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formula:C14H22O13Purezza:≥98%Colore e forma:SolidPeso molecolare:398.317CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formula:C22H18Cl2N8Purezza:97.94% - ≥95%Colore e forma:SolidPeso molecolare:465.34Ref: TM-T2310
2mg40,00€5mg60,00€10mg92,00€25mg152,00€50mg240,00€100mg384,00€200mg572,00€500mg888,00€1mL*10mM (DMSO)66,00€Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
Formula:C19H23NO4Purezza:99.02% - 99.73%Colore e forma:White PowderPeso molecolare:329.39Bergapten
CAS:Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.Formula:C12H8O4Purezza:99.48% - ≥95%Colore e forma:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Peso molecolare:216.19IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formula:C22H15Br2N3O4Purezza:98.92% - ≥95%Colore e forma:SolidPeso molecolare:545.18Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formula:C15H12O4Purezza:99.61% - >99.99%Colore e forma:SolidPeso molecolare:256.25MW-150 dihydrochloride dihydrate
CAS:MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.Formula:C24H29Cl2N5O2Colore e forma:SolidPeso molecolare:490.43Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purezza:97.21% - 99.94%Colore e forma:SolidPeso molecolare:450.51Ref: TM-T2500
2mg42,00€5mg63,00€10mg92,00€25mg136,00€50mg177,00€100mg254,00€200mg462,00€500mg742,00€1mL*10mM (DMSO)69,00€U0126
CAS:U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.Formula:C18H16N6S2Purezza:99.61%Colore e forma:White SolidPeso molecolare:380.49Tubastatin A Hydrochloride
CAS:Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).
Formula:C20H21N3O2·HClPurezza:97.24% - 99.15%Colore e forma:SolidPeso molecolare:371.86Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formula:C29H32N6O4SPurezza:98% - 99.42%Colore e forma:SolidPeso molecolare:560.67Ref: TM-T2066
5mg58,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€1mL*10mM (DMSO)71,00€AZD1208
CAS:AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
Formula:C21H21N3O2SPurezza:97.24% - 99.83%Colore e forma:SolidPeso molecolare:379.48U0126-EtOH
CAS:U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!Formula:C18H16N6S2·C2H6OPurezza:99.72% - 99.88%Colore e forma:SolidPeso molecolare:426.6Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurezza:98.89% - >99.99%Colore e forma:SolidPeso molecolare:454.63Ref: TM-T1818
1mg43,00€2mg56,00€5mg77,00€10mg87,00€25mg157,00€50mg230,00€100mg393,00€500mg930,00€1mL*10mM (DMSO)79,00€Apigenin
CAS:Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.Formula:C15H10O5Purezza:97.64% - 99.66%Colore e forma:Yellow Needles From Aqueous Pyridine SolidPeso molecolare:270.24LC3-mHTT-IN-AN2
CAS:LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formula:C15H10O4Purezza:98.82% - ≥98%Colore e forma:SolidPeso molecolare:254.24Tetrahydrocurcumin
CAS:Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formula:C21H24O6Purezza:97.81% - 98.82%Colore e forma:Solid PowderPeso molecolare:372.41Ligustilide
CAS:3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.Formula:C12H14O2Purezza:96.03% - 99.97%Colore e forma:Yellow Brown PowderPeso molecolare:190.24Isosorbide Mononitrate
CAS:Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.Formula:C6H9NO6Purezza:98.16%Colore e forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecolare:191.14Berbamine dihydrochloride
CAS:Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formula:C37H42Cl2N2O6Purezza:95% - 99.99%Colore e forma:SolidPeso molecolare:681.65Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purezza:≥98%Colore e forma:Brown PowderPeso molecolare:676.83Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:212.24Entinostat
CAS:Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.Formula:C21H20N4O3Purezza:98% - 99.74%Colore e forma:SolidPeso molecolare:376.41CCT128930 hydrochloride
CAS:CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.Formula:C18H21Cl2N5Purezza:98.55%Colore e forma:SolidPeso molecolare:378.3Ref: TM-T6303L
1mg49,00€5mg92,00€10mg148,00€25mg240,00€50mg359,00€100mg523,00€200mg772,00€1mL*10mM (DMSO)104,00€Gartanin
CAS:Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.Formula:C23H24O6Purezza:99.64% - 99.85%Colore e forma:SolidPeso molecolare:396.43Ref: TM-TN1677
1mg92,00€5mg283,00€10mg432,00€25mg697,00€50mg938,00€100mg1.293,00€1mL*10mM (DMSO)298,00€Tempol
CAS:Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formula:C9H18NO2Purezza:97% - 99.98%Colore e forma:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesPeso molecolare:172.25Autogramin-1
CAS:Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.Formula:C23H27N5O5SPurezza:97.69% - 99.25%Colore e forma:SolidPeso molecolare:485.56PTC-209 hydrobromide
CAS:PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in
Formula:C17H13Br2N5OS·HBrPurezza:99.91%Colore e forma:SolidPeso molecolare:576.1Ref: TM-T6178
1mg37,00€5mg78,00€10mg124,00€25mg265,00€50mg465,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)89,00€NSC 185058
CAS:NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.Formula:C11H9N3SPurezza:99.27%Colore e forma:SolidPeso molecolare:215.27PF-543 hydrochloride
CAS:PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formula:C27H32ClNO4SPurezza:98.9% - 99.93%Colore e forma:SolidPeso molecolare:502.1XL388
CAS:XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.Formula:C23H22FN3O4SPurezza:99.39% - 99.53%Colore e forma:SolidPeso molecolare:455.5Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formula:C64H116N22O19Purezza:>99.99%Colore e forma:SolidPeso molecolare:1497.74PF-06447475
CAS:PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.Formula:C17H15N5OPurezza:98.61% - 99.62%Colore e forma:SolidPeso molecolare:305.33Onjisaponin B
CAS:Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-Formula:C75H112O35Purezza:99.20% - 99.972%Colore e forma:SolidPeso molecolare:1573.67Ref: TM-TN1140
5mg92,00€10mg163,00€25mg266,00€50mg393,00€100mgPrezzo su richiesta1mL*10mM (DMSO)238,00€URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purezza:99.32% - 99.98%Colore e forma:SolidPeso molecolare:421.54A-867744
CAS:A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Formula:C20H19ClN2O3SPurezza:95.66%Colore e forma:SolidPeso molecolare:402.89XCT790
CAS:XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formula:C23H13F9N4O3SPurezza:99% - 99.61%Colore e forma:SolidPeso molecolare:596.42Spautin-1
CAS:Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Formula:C15H11F2N3Purezza:97.69% - 98.99%Colore e forma:SolidPeso molecolare:271.26Ref: TM-T1937
2mg37,00€5mg52,00€10mg66,00€25mg111,00€50mg197,00€100mg298,00€200mg444,00€1mL*10mM (DMSO)58,00€TA-01
CAS:TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Formula:C20H12F3N3Purezza:99.55% - 99.94%Colore e forma:SolidPeso molecolare:351.32Ref: TM-T4645
2mg34,00€5mg50,00€10mg80,00€25mg147,00€50mg224,00€100mg313,00€200mg439,00€1mL*10mM (DMSO)67,00€PI3Kδ-IN-15
CAS:CAL-101 (Idelalisib) is a selective inhibitor of p110δ; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ.Formula:C21H16FN7OPurezza:99.61%Colore e forma:SolidPeso molecolare:401.4Lanatoside C
CAS:Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.Formula:C49H76O20Purezza:98.3% - >99.99%Colore e forma:SolidPeso molecolare:985.12Hoechst 33342
CAS:Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!Formula:C27H28N6OPurezza:98.12% - 99.75%Colore e forma:Yellow-Green PowderPeso molecolare:452.55Sofalcone
CAS:Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.Formula:C27H30O6Purezza:97.55%Colore e forma:SolidPeso molecolare:450.52Hesperadin
CAS:Hesperadin(IC50=250 nM) effectively inhibits Aurora B.Formula:C29H32N4O3SPurezza:98.04% - 99.44%Colore e forma:SolidPeso molecolare:516.65Nitroprusside disodium dihydrate
CAS:Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.Formula:C5H4FeN6Na2O3Purezza:98%Colore e forma:Bright RedPeso molecolare:297.95UNC1999
CAS:UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).Formula:C33H43N7O2Purezza:99.19% - >99.99%Colore e forma:SolidPeso molecolare:569.74Ref: TM-T3057
1mg34,00€2mg46,00€5mg66,00€10mg92,00€25mg167,00€50mg259,00€100mg401,00€200mg580,00€1mL*10mM (DMSO)94,00€Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg90,00€5mg203,00€10mg350,00€25mg578,00€50mg797,00€100mg1.071,00€500mg2.187,00€1mL*10mM (DMSO)224,00€α-Thujone
CAS:α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formula:C10H16OPurezza:97.02% - 98.41%Colore e forma:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecolare:152.23Ivacaftor
CAS:Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,Formula:C24H28N2O3Purezza:99% - 99.98%Colore e forma:SolidPeso molecolare:392.49Ref: TM-T2588
1mg38,00€2mgPrezzo su richiesta5mg81,00€10mg127,00€25mg205,00€50mg304,00€100mg439,00€200mgPrezzo su richiesta1mL*10mM (DMSO)88,00€Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurezza:98% - 99.8%Colore e forma:SolidPeso molecolare:505.5Urolithin A
CAS:Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formula:C13H8O4Purezza:99.14% - 99.67%Colore e forma:SolidPeso molecolare:228.2Ref: TM-T7174
5mg47,00€10mg69,00€25mg123,00€50mg177,00€100mg304,00€200mg447,00€500mg713,00€1mL*10mM (DMSO)52,00€OSI-027
CAS:OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formula:C21H22N6O3Purezza:97.42%Colore e forma:SolidPeso molecolare:406.44Ref: TM-T6319
1mg39,00€2mg50,00€5mg81,00€10mg131,00€25mg235,00€50mg369,00€100mg537,00€1mL*10mM (DMSO)84,00€Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurezza:98% - 99.91%Colore e forma:Physical Description White Powder (Ntp 1992)Peso molecolare:301.32Ref: TM-T2802
5mg34,00€10mg52,00€25mg94,00€50mg165,00€100mg268,00€200mg399,00€500mg647,00€1mL*10mM (DMSO)38,00€Atorvastatin hemicalcium trihydrate
CAS:Atorvastatin hemicalcium trihydrate, an oral HMG-CoA reductase inhibitor, lowers blood lipids and inhibits SV-SMC with IC50s: 0.39/2.39 μM.Formula:C33H35FN2O5Ca·3H2OColore e forma:SolidPeso molecolare:632.73Nesolicaftor
CAS:Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.Formula:C18H18N4O4Purezza:99.79%Colore e forma:SolidPeso molecolare:354.36Ref: TM-T16681
1mg90,00€5mg203,00€10mg358,00€25mg617,00€50mg878,00€100mg1.189,00€1mL*10mM (DMSO)225,00€Rabusertib
CAS:Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.
Formula:C18H22BrN5O3Purezza:98.86% - 99.87%Colore e forma:SolidPeso molecolare:436.3Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formula:C35H28F3N5O2Purezza:98.3% - 99.33%Colore e forma:SolidPeso molecolare:607.62Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.
Formula:C29H25F4N3O5SPurezza:99.3% - 99.85%Colore e forma:SolidPeso molecolare:603.58Ref: TM-T4379
1mg87,00€5mg166,00€10mg248,00€25mg437,00€50mg665,00€100mg1.008,00€200mg1.520,00€500mg2.252,00€Aliskiren hydrochloride
CAS:Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is a selective, orally active, renin inhibitor (IC50: 1.5 nM). Cachexia.Formula:C30H54ClN3O6Colore e forma:SolidPeso molecolare:588.23Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purezza:98.40% - 99.73%Colore e forma:SolidPeso molecolare:443.54
