Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purezza:98.49% - 99.55%Colore e forma:SolidPeso molecolare:292.37Ref: TM-T1798
1mg35,00€5mg66,00€10mg96,00€25mg187,00€50mg279,00€100mg420,00€200mg607,00€1mL*10mM (DMSO)89,00€4EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formula:C18H12Cl2N4O4SPurezza:96.8% - 99.12%Colore e forma:SolidPeso molecolare:451.28Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purezza:97.79% - >99.99%Colore e forma:Yellow SolidPeso molecolare:384.24Ref: TM-T2399
5mg52,00€10mg64,00€25mg80,00€50mg96,00€100mg144,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)52,00€CZC-25146 hydrochloride
CAS:<p>CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.</p>Formula:C22H26ClFN6O4SPurezza:98.76%Colore e forma:SolidPeso molecolare:525Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Formula:C9H10O5Purezza:98.4% - 99.74%Colore e forma:SolidPeso molecolare:198.17SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purezza:99.47% - 99.92%Colore e forma:SolidPeso molecolare:402.91Ref: TM-T2170
5mg57,00€10mg86,00€25mg138,00€50mg243,00€100mg470,00€200mg717,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Vitexin
CAS:Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.Formula:C21H20O10Purezza:98.13% - 99.64%Colore e forma:Yellow PowderPeso molecolare:432.3810074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purezza:99.51% - 99.94%Colore e forma:SolidPeso molecolare:332.31Ref: TM-T3686
2mg42,00€5mg63,00€10mg88,00€25mg142,00€50mg225,00€100mg396,00€200mg565,00€500mg900,00€1mL*10mM (DMSO)69,00€KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formula:C26H29ClN2O4SPurezza:99.56% - 99.86%Colore e forma:White SolidPeso molecolare:501.04Ref: TM-T2697
1mg57,00€2mg79,00€5mg113,00€10mg155,00€25mg305,00€50mg378,00€100mg552,00€1mL*10mM (DMSO)127,00€Taxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purezza:94.91% - 98.9%Colore e forma:Yellowish PowderPeso molecolare:304.25RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurezza:99.56%Colore e forma:SolidPeso molecolare:518.41Ref: TM-T6296
1mg47,00€2mg63,00€5mg87,00€10mg147,00€25mg266,00€50mg435,00€100mg640,00€1mL*10mM (DMSO)99,00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purezza:99.99%Colore e forma:White Or Off-White PowderPeso molecolare:146.14IU1
CAS:IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂，可以穿透细胞，IC50为 4.7 μM。Formula:C18H21FN2OPurezza:98% - 99.3%Colore e forma:SolidPeso molecolare:300.37PF-3845
CAS:PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Formula:C24H23F3N4O2Purezza:99.54% - 99.58%Colore e forma:SolidPeso molecolare:456.46Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purezza:98.75% - 99.57%Colore e forma:SolidPeso molecolare:199.25Ref: TM-T4414
5mg73,00€10mg105,00€25mg207,00€50mg368,00€100mg652,00€500mg1.320,00€1mL*10mM (DMSO)81,00€ML-SA1
CAS:ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.Formula:C22H22N2O3Purezza:99.34% - 99.71%Colore e forma:SolidPeso molecolare:362.42Ref: TM-T23004
2mg37,00€5mg51,00€10mg81,00€25mg150,00€50mg244,00€100mg364,00€200mg550,00€1mL*10mM (DMSO)58,00€Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formula:C18H14N2O4Purezza:95.85% - 99.22%Colore e forma:SolidPeso molecolare:322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formula:C27H45IN2Purezza:98.60%Colore e forma:SolidPeso molecolare:524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€CX546
CAS:CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formula:C14H17NO3Purezza:99.75%Colore e forma:SolidPeso molecolare:247.295-Aminolevulinic acid hydrochloride
CAS:5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Formula:C5H10ClNO3Purezza:98% - 99.97%Colore e forma:White To Pale Yellow Crystals OrPeso molecolare:167.59Ulipristal acetate
CAS:Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Formula:C30H37NO4Purezza:98.83% - 99.94%Colore e forma:SolidPeso molecolare:475.62Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purezza:99.6% - 99.84%Colore e forma:SolidPeso molecolare:719.91Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purezza:98.67%Colore e forma:SolidPeso molecolare:487.93Ref: TM-T4S0797
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mg93,00€100mg125,00€500mg266,00€1mL*10mM (DMSO)55,00€Ginkgetin
CAS:Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Formula:C32H22O10Purezza:98.63% - 99.94%Colore e forma:SolidPeso molecolare:566.51Ref: TM-T4S2126
1mg48,00€5mg97,00€10mg155,00€25mg264,00€50mg390,00€100mg575,00€200mg820,00€1mL*10mM (DMSO)120,00€Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Formula:C10H19N2O5PPurezza:99.99% - ≥95%Colore e forma:SolidPeso molecolare:278.24Ref: TM-T6641
1mg35,00€5mg71,00€10mg87,00€25mg160,00€50mg244,00€100mg383,00€200mg557,00€1mL*10mM (DMSO)71,00€Metformin
CAS:<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Formula:C4H11N5Purezza:99.77% - >99.99%Colore e forma:SolidPeso molecolare:129.16Indomethacin farnesil
CAS:Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.Formula:C34H40ClNO4Purezza:97.29%Colore e forma:SolidPeso molecolare:562.14SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurezza:98% - 99.84%Colore e forma:Pale YellowPeso molecolare:331.34CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Formula:C29H30ClN5O2SPurezza:99.69%Colore e forma:SolidPeso molecolare:548.1Ref: TM-T14860
1mg52,00€2mg74,00€5mg119,00€10mg170,00€25mg354,00€50mg550,00€100mg792,00€1mL*10mM (DMSO)144,00€Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purezza:96.68% - 98.229%Colore e forma:SolidPeso molecolare:320.25MHY1485
CAS:MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.Formula:C17H21N7O4Purezza:97.74% - >99.99%Colore e forma:SolidPeso molecolare:387.39(-)-Epicatechin gallate
CAS:(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.Formula:C22H18O10Purezza:99.16% - 99.93%Colore e forma:SolidPeso molecolare:442.371-Monomyristin
CAS:1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFormula:C17H34O4Purezza:99.58%Colore e forma:SolidPeso molecolare:302.45Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purezza:97.82% - 98.3%Colore e forma:SolidPeso molecolare:676.66CFTR(inh)-172
CAS:CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.Formula:C18H10F3NO3S2Purezza:98% - 99.72%Colore e forma:SolidPeso molecolare:409.4Ref: TM-T2355
1mg35,00€2mg46,00€5mg66,00€10mg97,00€25mg188,00€50mg359,00€100mg530,00€1mL*10mM (DMSO)69,00€Syringin
CAS:Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.Formula:C17H24O9Purezza:98.89% - 99.96%Colore e forma:SolidPeso molecolare:372.37VER-155008
CAS:<p>VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.</p>Formula:C25H23Cl2N7O4Purezza:97.03% - 99.55%Colore e forma:SolidPeso molecolare:556.4Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formula:C50H46CaF2N2O8Purezza:98.89% - >99.99%Colore e forma:White To Off-White PowderPeso molecolare:880.98Ref: TM-T2534
5mg39,00€10mg52,00€25mg70,00€50mg92,00€100mg127,00€200mg227,00€500mgPrezzo su richiesta1mL*10mM (DMSO)59,00€Tarenflurbil
CAS:Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.Formula:C15H13FO2Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:244.26Efavirenz
CAS:Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formula:C14H9ClF3NO2Purezza:99.2% - 99.84%Colore e forma:White To Slightly Pink Crystalline PowderPeso molecolare:315.67Ref: TM-T2393
1g404,00€5mg42,00€10mg52,00€25mg71,00€50mg89,00€100mg116,00€500mg273,00€1mL*10mM (DMSO)49,00€D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Formula:C23H18N4O3Purezza:99.7% - 99.96%Colore e forma:SolidPeso molecolare:398.41Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formula:C30H23N5OPurezza:97.64% - 99.85%Colore e forma:SolidPeso molecolare:469.54Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurezza:99.74%Colore e forma:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecolare:131.17MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formula:C24H23N5Purezza:97.35% - 99.27%Colore e forma:SolidPeso molecolare:381.47Ref: TM-T5494
1mg39,00€5mg96,00€10mg153,00€25mg305,00€50mg454,00€100mg655,00€500mg1.406,00€1mL*10mM (DMSO)114,00€Lumefantrine
CAS:Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formula:C30H32Cl3NOPurezza:98.36%Colore e forma:Yellow SolidPeso molecolare:528.94Shogaol
CAS:<p>6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.</p>Formula:C17H24O3Purezza:98.26% - 99.93%Colore e forma:SolidPeso molecolare:276.37Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H19N5Purezza:98% - 99.77%Colore e forma:SolidPeso molecolare:329.4Irinotecan
CAS:Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formula:C33H38N4O6Purezza:98% - 99.92%Colore e forma:SolidPeso molecolare:586.68LY2109761
CAS:LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Formula:C26H27N5O2Purezza:97% - 99.83%Colore e forma:SolidPeso molecolare:441.52Ref: TM-T2123
2mg47,00€5mg70,00€10mg111,00€25mg188,00€50mg335,00€100mg507,00€200mg730,00€1mL*10mM (DMSO)77,00€trifarotene
CAS:<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Formula:C29H33NO4Purezza:99.51%Colore e forma:SolidPeso molecolare:459.58Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Formula:C13H16N2O2Purezza:98% - 99.89%Colore e forma:Pale Yellow Leaflets From Benzene SolidPeso molecolare:232.28Peiminine
CAS:<p>1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.</p>Formula:C27H43NO3Purezza:99.52% - ≥95%Colore e forma:White PowderPeso molecolare:429.64Ridaforolimus
CAS:<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Formula:C53H84NO14PPurezza:90.00% - 98.55%Colore e forma:Off-White SolidPeso molecolare:990.21Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purezza:98.72% - 99.55%Colore e forma:SolidPeso molecolare:284.26Ref: TM-T6S1315
1mg39,00€5mg74,00€10mg96,00€25mg156,00€50mg220,00€100mg325,00€200mg472,00€1mL*10mM (DMSO)88,00€SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formula:C23H14ClFN2O2Purezza:99.75%Colore e forma:SolidPeso molecolare:404.82Enzalutamide
CAS:Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formula:C21H16F4N4O2SPurezza:99% - 99.93%Colore e forma:SolidPeso molecolare:464.44Ref: TM-T6002
5mg48,00€10mg56,00€25mg74,00€50mg96,00€100mg154,00€200mg187,00€500mg274,00€1mL*10mM (DMSO)52,00€Arctigenin
CAS:(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formula:C21H24O6Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:372.41PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purezza:99.22%Colore e forma:SolidPeso molecolare:185.22Ref: TM-T6954
5mg51,00€10mg73,00€25mg140,00€50mg207,00€100mg368,00€200mg547,00€500mg877,00€1mL*10mM (DMSO)57,00€Fexaramine
CAS:Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formula:C32H36N2O3Purezza:98.87% - 99.61%Colore e forma:SolidPeso molecolare:496.64GSK2656157
CAS:<p>GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.</p>Formula:C23H21FN6OPurezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:416.45PD-166866
CAS:PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formula:C20H24N6O3Purezza:98.29%Colore e forma:SolidPeso molecolare:396.44ICCB-19 hydrochloride
CAS:ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formula:C12H22ClN3OSPurezza:99.3%Colore e forma:SolidPeso molecolare:291.84Ref: TM-T8931L
5mg35,00€10mg52,00€25mg96,00€50mg145,00€100mg210,00€200mg313,00€500mg495,00€1mL*10mM (DMSO)35,00€Pictilisib
CAS:Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formula:C23H27N7O3S2Purezza:98.69% - 99.97%Colore e forma:SolidPeso molecolare:513.64SF1670
CAS:SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.Formula:C19H17NO3Purezza:98.25% - 98.54%Colore e forma:SolidPeso molecolare:307.34Ref: TM-T6667
1mg44,00€2mg55,00€5mg88,00€10mg125,00€25mg273,00€50mg500,00€100mg740,00€1mL*10mM (DMSO)97,00€Thiamet G
CAS:Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!Formula:C9H16N2O4SPurezza:99.06% - 99.98%Colore e forma:SolidPeso molecolare:248.3Ref: TM-T6056
2mg44,00€5mg63,00€10mg93,00€25mg188,00€50mg343,00€100mg510,00€500mg1.130,00€1mL*10mM (DMSO)63,00€Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purezza:98.83% - 99.96%Colore e forma:Less Crystalline Solid Colorless Crystalline SolidPeso molecolare:410.50Ref: TM-T2939
5mg43,00€10mg56,00€25mg86,00€50mg96,00€100mg144,00€200mg182,00€500mg306,00€1mL*10mM (DMSO)56,00€6-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurezza:98.75% - >99.99%Colore e forma:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecolare:167.19Calcineurin substrate acetate
Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.Formula:C94H154N28O31Purezza:97.59%Colore e forma:SolidPeso molecolare:2172.4Cinobufagin
CAS:<p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>Formula:C26H34O6Purezza:97.77% - 99.97%Colore e forma:SolidPeso molecolare:442.54Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormula:C23H31FO6Purezza:96.92% - 98.03%Colore e forma:Crystalline SolidPeso molecolare:422.49Vinblastine sulfate
CAS:Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).Formula:C46H58N4O9·H2SO4Purezza:97.81% - 99.82%Colore e forma:White PowderPeso molecolare:909.06Tacrolimus
CAS:<p>Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein</p>Formula:C44H69NO12Purezza:98% - 99.94%Colore e forma:White Or Off-White Crystalline PowderPeso molecolare:804.02Glycycoumarin
CAS:Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.Formula:C21H20O6Purezza:97.64% - 99.78%Colore e forma:SolidPeso molecolare:368.38Ref: TM-TN1702
1mg42,00€5mg81,00€10mg122,00€25mg235,00€50mg348,00€100mg515,00€200mg743,00€1mL*10mM (DMSO)89,00€PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Formula:C17H13Br2N5OSPurezza:99.43% - 99.887%Colore e forma:SolidPeso molecolare:495.19S29434
CAS:S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).Formula:C21H18N4O3Purezza:99.92%Colore e forma:SolidPeso molecolare:374.39PH-797804
CAS:PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.Formula:C22H19BrF2N2O3Purezza:97.90% - 98.27%Colore e forma:SolidPeso molecolare:477.3Ref: TM-T1974
1mg46,00€5mg94,00€10mg144,00€25mg255,00€50mg406,00€100mg628,00€500mg1.320,00€1mL*10mM (DMSO)97,00€Isradipine
CAS:Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.Formula:C19H21N3O5Purezza:99.84% - 99.95%Colore e forma:Yellow SolidPeso molecolare:371.39AM580
CAS:AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )Formula:C22H25NO3Purezza:98% - 99.84%Colore e forma:SolidPeso molecolare:351.44Ref: TM-T5854
2mg39,00€5mg57,00€10mg87,00€25mg164,00€50mg316,00€100mg469,00€500mg1.064,00€1mL*10mM (DMSO)64,00€Bakuchiol
CAS:Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Formula:C18H24OPurezza:98.04% - 99.05%Colore e forma:Brownish Yellow Liquid ViscousPeso molecolare:256.38IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurezza:98.76% - 99.61%Colore e forma:SolidPeso molecolare:483.63Ref: TM-T6176
1mg40,00€2mg52,00€5mg88,00€10mg139,00€25mg245,00€50mg406,00€100mg582,00€200mg825,00€1mL*10mM (DMSO)87,00€NL-1
CAS:NL-1 is a mitoNEET inhibitor with antileukemic effect.Formula:C18H25NO3SPurezza:98.64%Colore e forma:SolidPeso molecolare:335.46JH-II-127
CAS:JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Formula:C19H21ClN6O3Purezza:98.32%Colore e forma:SolidPeso molecolare:416.86Ref: TM-T7155
2mg46,00€5mg70,00€10mg101,00€25mg170,00€50mg273,00€100mg386,00€200mg550,00€1mL*10mM (DMSO)77,00€Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formula:C17H18N6Purezza:99.4% - >99.99%Colore e forma:SolidPeso molecolare:306.36Silibinin
CAS:Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.Formula:C25H22O10Purezza:97.98% - 98.37%Colore e forma:SolidPeso molecolare:482.44Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurezza:99.99%Colore e forma:SolidPeso molecolare:464.59Regorafenib Hydrochloride
CAS:<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Formula:C21H16Cl2F4N4O3Purezza:99.56%Colore e forma:SolidPeso molecolare:519.28Aloe emodin
CAS:Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV （IC50=1 μg/mL） and EV71（IC50=0.33 μg/mL ）.Formula:C15H10O5Purezza:97.00% - 99.61%Colore e forma:Orange SolidPeso molecolare:270.24GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormula:C31H39N7O2Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:541.69LYN-1604 dihydrochloride
CAS:LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formula:C33H45Cl4N3O2Purezza:98.95% - 99.92%Colore e forma:SolidPeso molecolare:657.54Ref: TM-T8808L
1mg35,00€5mg78,00€10mg117,00€25mg212,00€50mg316,00€100mg447,00€200mg628,00€1mL*10mM (DMSO)101,00€OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurezza:98.69%Colore e forma:SolidPeso molecolare:533.59Ref: TM-T5485
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€1mL*10mM (DMSO)220,00€Ixazomib
CAS:<p>Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.</p>Formula:C14H19BCl2N2O4Purezza:98% - 98.92%Colore e forma:SolidPeso molecolare:361.03SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formula:C24H28Cl2N2O4Purezza:99.00% - ≥95%Colore e forma:SolidPeso molecolare:479.4Oxyphenisatin acetate
CAS:Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.Formula:C24H19NO5Purezza:98% - 99.35%Colore e forma:SolidPeso molecolare:401.41Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formula:C25H35ClN4O2SPurezza:99.36%Colore e forma:SolidPeso molecolare:491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€1mL*10mM (DMSO)73,00€YM-201636
CAS:YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formula:C25H21N7O3Purezza:93.28% - 98.3%Colore e forma:SolidPeso molecolare:467.48Ref: TM-T6110
1mg48,00€2mg64,00€5mg96,00€10mg173,00€25mg359,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)97,00€Doramapimod
CAS:Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formula:C31H37N5O3Purezza:97.14% - 98.80%Colore e forma:SolidPeso molecolare:527.66Ref: TM-T6277
1g562,00€5mg37,00€10mg55,00€25mg79,00€50mg92,00€100mg127,00€200mg225,00€500mg379,00€1mL*10mM (DMSO)44,00€Veliparib dihydrochloride
CAS:Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formula:C13H18Cl2N4OPurezza:98% - 99.81%Colore e forma:SolidPeso molecolare:317.21Ambroxol hydrochloride
CAS:Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formula:C13H18Br2N2O·HClPurezza:99.70%Colore e forma:White To Yellowish Crystalline PowderPeso molecolare:414.56CFTR corrector 2
CAS:CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.Formula:C27H23FN4O4Purezza:99.66%Colore e forma:SolidPeso molecolare:486.49Ref: TM-T5312
2mg39,00€5mg58,00€10mg85,00€25mg156,00€50mg226,00€100mg335,00€200mg469,00€1mL*10mM (DMSO)63,00€ZLN005
CAS:ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.Formula:C17H18N2Purezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:250.34TWS119
CAS:TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFormula:C18H14N4O2Purezza:98.14% - 99.63%Colore e forma:SolidPeso molecolare:318.33Rutin hydrate
CAS:Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formula:C27H32O17Purezza:97.23%Colore e forma:SolidPeso molecolare:628.53Liensinine diperchlorate
CAS:Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.Formula:C37H44Cl2N2O14Purezza:99.8% - ≥95%Colore e forma:SolidPeso molecolare:811.67Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purezza:95.87% - 99.36%Colore e forma:SolidPeso molecolare:622.83Belinostat
CAS:Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Formula:C15H14N2O4SPurezza:99.75% - >99.99%Colore e forma:SolidPeso molecolare:318.35Ref: TM-T8517
5mg48,00€10mg69,00€25mg97,00€50mg144,00€100mg207,00€200mg306,00€500mg518,00€1mL*10mM (DMSO)63,00€Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purezza:96.01% - ≥98%Colore e forma:SolidPeso molecolare:394.47Ref: TM-T6055
1mg59,00€2mg86,00€5mg124,00€10mg180,00€25mg309,00€50mg427,00€100mg605,00€1mL*10mM (DMSO)139,00€Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purezza:99.88%Colore e forma:SolidPeso molecolare:344.36Veliparib
CAS:Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formula:C13H16N4OPurezza:98.66% - 99%Colore e forma:SolidPeso molecolare:244.29Ref: TM-T2591
5mg57,00€10mg81,00€25mg127,00€50mg207,00€100mg331,00€200mg540,00€500mg852,00€1mL*10mM (DMSO)64,00€Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purezza:98.22% - 99.64%Colore e forma:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecolare:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Purezza:97.45%Colore e forma:SolidPeso molecolare:308.33Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Formula:C27H45NO2Purezza:99.94% - 99.98%Colore e forma:SolidPeso molecolare:415.65GNE-7915
CAS:GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formula:C19H21F4N5O3Purezza:98% - ≥95%Colore e forma:SolidPeso molecolare:443.4Ref: TM-T1945
5mg47,00€10mg62,00€25mg114,00€50mg187,00€100mg316,00€200mg410,00€500mg680,00€1mL*10mM (DMSO)50,00€Dehydropachymic acid
CAS:Dehydropachymic acid shows antiinflammatory activity.Formula:C33H50O5Purezza:99.61% - 99.78%Colore e forma:SolidPeso molecolare:526.75Notoginsenoside Fc
CAS:<p>1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.</p>Formula:C58H98O26Purezza:99.22% - 99.94%Colore e forma:SolidPeso molecolare:1211.38Cilofexor
CAS:Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formula:C28H22Cl3N3O5Purezza:99.86% - ≥95%Colore e forma:SolidPeso molecolare:586.85Ref: TM-T7436
1mg50,00€2mg77,00€5mg124,00€10mg188,00€25mg376,00€50mg567,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)158,00€Rosuvastatin
CAS:<p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>Formula:C22H28FN3O6SPurezza:95.24% - 99.8%Colore e forma:SolidPeso molecolare:481.54STF-31
CAS:STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Formula:C23H25N3O3SPurezza:99.55% - >99.99%Colore e forma:SolidPeso molecolare:423.53Ref: TM-T5S2358
1mg52,00€2mg72,00€5mg111,00€10mg144,00€25mg207,00€50mg311,00€100mg472,00€1mL*10mM (DMSO)123,00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purezza:98.82%Colore e forma:SolidPeso molecolare:394.47Liensinine
CAS:1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.Formula:C37H42N2O6Purezza:98.92% - 99.93%Colore e forma:White-Like PowderPeso molecolare:610.74Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formula:C33H34FN2O5CaPurezza:99.27% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:577.67CZC-54252
CAS:CZC-54252 is a potent inhibitor of LRRK2.Formula:C22H25ClN6O4SPurezza:99.39%Colore e forma:SolidPeso molecolare:504.99Nilotinib monohydrochloride monohydrate
CAS:<p>Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine</p>Formula:C28H22F3N7O·HCl·H2OPurezza:99.93%Colore e forma:SolidPeso molecolare:583.99Autogramin-2
CAS:Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by eitherFormula:C21H27N3O4SPurezza:96.25%Colore e forma:SolidPeso molecolare:417.52Vismodegib
CAS:<p>Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).</p>Formula:C19H14Cl2N2O3SPurezza:98% - 99.82%Colore e forma:SolidPeso molecolare:421.3PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Formula:C18H11F3N2OPurezza:95.49% - 99.16%Colore e forma:SolidPeso molecolare:328.29Ref: TM-T3105
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg173,00€50mg273,00€100mg432,00€1mL*10mM (DMSO)77,00€Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purezza:98% - 99.96%Colore e forma:SolidPeso molecolare:615.39Levosimendan
CAS:<p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>Formula:C14H12N6OPurezza:99.37% - 99.91%Colore e forma:Yellow Crystalline PowderPeso molecolare:280.28Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formula:C16H12O5Purezza:98% - 99.8%Colore e forma:Yellow CrystalPeso molecolare:284.26SU9516
CAS:SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formula:C13H11N3O2Purezza:99.34% - 99.96%Colore e forma:SolidPeso molecolare:241.25Ref: TM-T6167
1mg35,00€2mg50,00€5mg73,00€10mg103,00€25mg208,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)74,00€10058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purezza:98% - 99.87%Colore e forma:SolidPeso molecolare:249.35Soyasapogenol B
CAS:Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.Formula:C30H50O3Purezza:99.51% - 99.81%Colore e forma:SolidPeso molecolare:458.72CZC-25146
CAS:CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formula:C22H25FN6O4SPurezza:97.68%Colore e forma:SolidPeso molecolare:488.54N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formula:C25H37NOPurezza:98.7% - 99.92%Colore e forma:SolidPeso molecolare:367.57Ref: TM-TN1965
1mg86,00€5mg180,00€10mg274,00€25mg465,00€50mg663,00€100mg919,00€200mg1.216,00€1mL*10mM (DMSO)187,00€Amsacrine hydrochloride
CAS:Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formula:C21H20ClN3O3SPurezza:99.05% - 99.92%Colore e forma:SolidPeso molecolare:429.92Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurezza:97.16% - 99.63%Colore e forma:Almost White SolidPeso molecolare:383.37Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formula:C26H22N2O2Purezza:97.12% - 99.96%Colore e forma:SolidPeso molecolare:394.47Ref: TM-T6671
2mg43,00€5mg58,00€10mg93,00€25mg178,00€50mg343,00€100mg509,00€500mg1.121,00€1mL*10mM (DMSO)58,00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.88%Colore e forma:SolidPeso molecolare:294.39GNE-9605
CAS:<p>GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).</p>Formula:C17H20ClF4N7OPurezza:98.55% - 98.75%Colore e forma:SolidPeso molecolare:449.83PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purezza:97% - 99.79%Colore e forma:SolidPeso molecolare:394.12Ref: TM-T6961
1mg42,00€5mg88,00€10mg137,00€25mg205,00€50mg276,00€100mg434,00€200mg638,00€1mL*10mM (DMSO)88,00€Rotenone
CAS:Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formula:C23H22O6Purezza:89.58% - 99.88%Colore e forma:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecolare:394.42SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:264.12Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purezza:98.56% - 99.9%Colore e forma:Off-White SolidPeso molecolare:485.94Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purezza:99.51% - 99.61%Colore e forma:SolidPeso molecolare:526.88Ref: TM-T4367
1mg49,00€5mg99,00€10mg168,00€25mg335,00€50mg477,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)116,00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purezza:98.81% - 99.65%Colore e forma:SolidPeso molecolare:624.77Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purezza:99.75% - 99.94%Colore e forma:SolidPeso molecolare:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purezza:99.91%Colore e forma:White To Off-White PowderPeso molecolare:290.1Wogonoside
CAS:<p>Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.</p>Formula:C22H20O11Purezza:98.24% - >99.99%Colore e forma:SolidPeso molecolare:460.39Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurezza:99.58% - 99.88%Colore e forma:SolidPeso molecolare:413.49Chloroquine
CAS:Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formula:C18H26ClN3Purezza:99.5% - 99.98%Colore e forma:White To Slightly Yellow Crystalline Powder SolidPeso molecolare:319.87A-484954
CAS:A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Formula:C13H15N5O3Purezza:97.47% - 99.86%Colore e forma:SolidPeso molecolare:289.29Ref: TM-TQ0137
1mg43,00€2mg56,00€5mg88,00€10mg144,00€25mg305,00€50mg543,00€100mg775,00€1mL*10mM (DMSO)103,00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purezza:99.17% - 99.78%Colore e forma:SolidPeso molecolare:328.32Leonurine
CAS:<p>Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.</p>Formula:C14H21N3O5Purezza:98.55%Colore e forma:White Crystalline PowderPeso molecolare:311.33Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purezza:98.35% - 99.89%Colore e forma:SolidPeso molecolare:383.46Ref: TM-T2277
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg225,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)55,00€Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurezza:99.76%Colore e forma:SolidPeso molecolare:523.75Ref: TM-T8946
1mg44,00€5mg87,00€10mg123,00€25mg198,00€50mg274,00€100mg386,00€200mg525,00€1mL*10mM (DMSO)90,00€Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formula:C19H20F2N4O4Purezza:99.52% - 99.99%Colore e forma:SolidPeso molecolare:406.38BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurezza:99.41% - 99.95%Colore e forma:SolidPeso molecolare:600.02Ref: TM-T1959
2mg52,00€5mg71,00€10mg107,00€25mg192,00€50mg274,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)111,00€CCT007093
CAS:CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formula:C15H12OS2Purezza:98% - 99.88%Colore e forma:SolidPeso molecolare:272.39Salubrinal
CAS:Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formula:C21H17Cl3N4OSPurezza:97.25% - >99.99%Colore e forma:SolidPeso molecolare:479.81Ref: TM-T3045
2mg42,00€5mg62,00€10mg93,00€25mg163,00€50mg274,00€100mg465,00€500mg1.035,00€1mL*10mM (DMSO)67,00€Vacuolin-1
CAS:Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.Formula:C26H24IN7OPurezza:97.20% - 98.45%Colore e forma:SolidPeso molecolare:577.42Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purezza:98.65% - 99.76%Colore e forma:SolidPeso molecolare:402.39Ref: TM-T2834
5mg57,00€10mg88,00€25mg124,00€50mg168,00€100mg265,00€200mg393,00€500mg653,00€1mL*10mM (DMSO)59,00€Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:638.82Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formula:C20H19NO3Purezza:99.83%Colore e forma:Solid CompactPeso molecolare:321.37Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:515.6UNC0638
CAS:UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.Formula:C30H47N5O2Purezza:98.88% - 99.53%Colore e forma:SolidPeso molecolare:509.73CA-5f
CAS:CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formula:C24H24N2O3Purezza:99.69%Colore e forma:SolidPeso molecolare:388.46Fangchinoline
CAS:Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:608.72AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purezza:99.87% - 99.95%Colore e forma:SolidPeso molecolare:408.45Fluvastatin
CAS:Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.Formula:C24H26FNO4Purezza:98.94%Colore e forma:SolidPeso molecolare:411.47Ketanserin tartrate
CAS:Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.Formula:C26H28FN3O9Purezza:99.68%Colore e forma:SolidPeso molecolare:545.51Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurezza:98.45%Colore e forma:SolidPeso molecolare:392.37mTOR inhibitor-8
CAS:mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for the study of non-small cell lung cancer.Formula:C24H19ClN4OSPurezza:98.11%Colore e forma:SolidPeso molecolare:446.95Ref: TM-T36316
1mg52,00€5mg111,00€10mg180,00€25mg359,00€50mg588,00€100mg944,00€1mL*10mM (DMSO)116,00€ML 145
CAS:ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)Formula:C24H22N2O5S2Purezza:97.74%Colore e forma:SolidPeso molecolare:482.57Ref: TM-T12074
1mg50,00€5mg105,00€10mg158,00€25mg264,00€50mg430,00€100mg605,00€1mL*10mM (DMSO)115,00€Doxorubicin
CAS:Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formula:C27H29NO11Purezza:99.31%Colore e forma:Red Crystalline Solid SolidPeso molecolare:543.52Ezetimibe ketone
CAS:Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.Formula:C24H19F2NO3Purezza:99.32%Colore e forma:White Crystalline SolidPeso molecolare:407.41Chenodeoxycholic Acid sodium salt
CAS:Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.Formula:C24H39NaO4Purezza:99.68% - 99.72%Colore e forma:SolidPeso molecolare:414.55H-89
CAS:H-89 is a PKA inhibitor, a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.Formula:C20H20BrN3O2SPurezza:98.06%Colore e forma:Off-White PowderPeso molecolare:446.36Ref: TM-T11524
5mg40,00€10mg59,00€25mg114,00€50mg170,00€100mg254,00€500mg627,00€1mL*10mM (DMSO)44,00€SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurezza:97.79%Colore e forma:SolidPeso molecolare:413.9740 Y-P
CAS:740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!Formula:C141H222N43O39PS3Purezza:98.3% - 99.87%Colore e forma:SolidPeso molecolare:3270.7Sitagliptin phosphate monohydrate
CAS:Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.Formula:C16H15F6N5O·H3PO4·H2OPurezza:99.85% - 99.98%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:523.33Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purezza:97.09% - 99.60%Colore e forma:Light Yellow SolidPeso molecolare:351.40Irinotecan-d10 Hydrochloride
CAS:Irinotecan-d10 Hydrochloride is a deuterated compound of Irinotecan Hydrochloride. Irinotecan Hydrochloride has a CAS number of 100286-90-6. Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death. Because ongoing DNA synthesis is necessary for irinotecan to exert its cytotoxic effects, it is classified as an S-phase-specific agent.Formula:C33H29D10ClN4O6Colore e forma:SolidPeso molecolare:633.20Tigecycline-d9
CAS:Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.Formula:C29H30D9N5O8Colore e forma:SolidPeso molecolare:594.70Lovastatin-d3
CAS:Lovastatin-d3 is a deuterated compound of Lovastatin. Lovastatin has a CAS number of 75330-75-5. Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.Formula:C24H33D3O5Colore e forma:SolidPeso molecolare:407.56Gefitinib-d6
CAS:Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).Formula:C22H18D6ClFN4O3Colore e forma:SolidPeso molecolare:452.94Reserpine-d9
CAS:Reserpine-d9 is a deuterated compound of Reserpine. Reserpine has a CAS number of 50-55-5. Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.Formula:C33H31D9N2O9Peso molecolare:617.73Rosuvastatin-d6 Sodium Salt
CAS:Rosuvastatin-d6 Sodium Salt is a deuterated compound of Rosuvastatin Sodium Salt. Rosuvastatin Sodium Salt has a CAS number of 1007871-86-4.Formula:C22H21D6FN3NaO6SColore e forma:SolidPeso molecolare:509.56Atorvastatin
CAS:Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formula:C33H35FN2O5Purezza:99.37% - 99.69%Colore e forma:SolidPeso molecolare:558.64MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurezza:99.22%Colore e forma:SolidPeso molecolare:461.94Bexarotene
CAS:Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Formula:C24H28O2Purezza:99% - 99.65%Colore e forma:White SolidPeso molecolare:348.48BGT226 maleate
CAS:<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Formula:C28H25F3N6O2·C4H4O4Purezza:97.75% - 98.78%Colore e forma:SolidPeso molecolare:650.6Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44Ref: TM-T2S2362
1mg94,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€200mg1.491,00€1mL*10mM (DMSO)255,00€VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purezza:99% - >99.99%Colore e forma:SolidPeso molecolare:404.32Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purezza:99.46% - 99.66%Colore e forma:SolidPeso molecolare:441.46Alisol A
CAS:<p>Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.</p>Formula:C30H50O5Purezza:99.77% - 99.94%Colore e forma:SolidPeso molecolare:490.71Rac-Efavirenz
CAS:Rac-Efavirenz is a non stereospecific structure of Efavirenz.Formula:C14H9ClF3NO2Colore e forma:SolidPeso molecolare:315.67Metyrapone Tartrate
CAS:Metyrapone Tartrate: a test inhibitor for diagnosing Cushing's; blocks steroid 11-beta-hydroxylase.Formula:C22H26N2O13Colore e forma:SolidPeso molecolare:526.45Euchrysine 3RX
CAS:Euchrysine 3RX is an agent of bioactive chemicals.Formula:C20H26BrCl2N3OPurezza:98%Colore e forma:Brown PowderPeso molecolare:475.25
