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Autofagia

Autofagia

Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.

Trovati 1478 prodotti di "Autofagia"

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  • Lapatinib Ditosylate

    CAS:
    Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
    Formula:C29H26ClFN4O4S·2C7H8O3S
    Purezza:99.41%
    Colore e forma:Yellow Solid
    Peso molecolare:925.46
  • Fluvastatin sodium

    CAS:
    Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol
    Formula:C24H25FNNaO4
    Purezza:98.54% - 99.56%
    Colore e forma:Light Yellow Solid Powder
    Peso molecolare:433.45
  • Lapatinib ditosylate monohydrate

    CAS:
    <p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>
    Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2O
    Purezza:98% - 99.41%
    Colore e forma:Colourless To Light-Yellow Crystal
    Peso molecolare:943.47
  • Erlotinib

    CAS:
    Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
    Formula:C22H23N3O4
    Purezza:98.19% - 99.98%
    Colore e forma:White To Off-White Powder
    Peso molecolare:393.44
  • Dexamethasone acetate

    CAS:
    <p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>
    Formula:C24H31FO6
    Purezza:99.22% - 99.65%
    Colore e forma:White Or Almost White Crystalline Powder
    Peso molecolare:434.50
  • AZD7624

    CAS:
    AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
    Formula:C27H30FN5O3
    Purezza:98.82%
    Colore e forma:Solid
    Peso molecolare:491.56
  • Spironolactone

    CAS:
    Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.
    Formula:C24H32O4S
    Purezza:99.87%
    Colore e forma:White Powder
    Peso molecolare:416.57
  • Chenodeoxycholic acid

    CAS:
    <p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>
    Formula:C24H40O4
    Purezza:99.70% - 99.93%
    Colore e forma:White - Almost White Solid Powder
    Peso molecolare:392.57
  • Itraconazole

    CAS:
    Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
    Formula:C35H38Cl2N8O4
    Purezza:98% - 99.90%
    Colore e forma:Off-White Crystalline Solid
    Peso molecolare:705.63
  • Vancomycin hydrochloride

    CAS:
    Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!
    Formula:C66H76Cl3N9O24
    Purezza:97.20% - 99.19%
    Colore e forma:Off White Powder
    Peso molecolare:1485.71
  • Reserpine

    CAS:
    <p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>
    Formula:C33H40N2O9
    Purezza:98.85% - 99.81%
    Colore e forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)
    Peso molecolare:608.68
  • ZX-29

    CAS:
    ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.
    Formula:C23H28ClN7O3S
    Purezza:98.32%
    Colore e forma:Solid
    Peso molecolare:518.03
  • LG-100064

    CAS:
    LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)
    Formula:C23H26O3
    Purezza:98.65%
    Colore e forma:Solid
    Peso molecolare:350.45
  • Pyrazinamide

    CAS:
    Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide
    Formula:C5H5N3O
    Purezza:99.71% - 99.9%
    Colore e forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)
    Peso molecolare:123.11
  • Raloxifene hydrochloride

    CAS:
    Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.
    Formula:C28H28ClNO4S
    Purezza:98% - 99.97%
    Colore e forma:Light Yellow Solid
    Peso molecolare:510.044
  • Lomustine

    CAS:
    Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.
    Formula:C9H16ClN3O2
    Purezza:98.36% - 99.44%
    Colore e forma:Solid Solid
    Peso molecolare:233.7
  • Crustecdysone

    CAS:
    <p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>
    Formula:C27H44O7
    Purezza:99.06% - 99.67%
    Colore e forma:Canary Yellow Fine Powder
    Peso molecolare:480.63
  • Matrine

    CAS:
    <p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>
    Formula:C15H24N2O
    Purezza:97.16% - >99.99%
    Colore e forma:Solid
    Peso molecolare:248.36
  • Nicardipine hydrochloride

    CAS:
    <p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>
    Formula:C26H30ClN3O6
    Purezza:99.58% - 99.89%
    Colore e forma:Yellow Solid
    Peso molecolare:515.99
  • Sorafenib tosylate

    CAS:
    <p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>
    Formula:C21H16ClF3N4O3·C7H8O3S
    Purezza:99.24% - 99.94%
    Colore e forma:White To Off-White Crystalline Powder
    Peso molecolare:637.03