PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 235 prodotti per "PI3K".
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VS-5584
CAS:VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.Formula:C17H22N8OPurezza:97.82% - 99.54%Colore e forma:White SolidPeso molecolare:354.41TGX-221
CAS:TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.Formula:C21H24N4O2Purezza:99.60% - >99.99%Colore e forma:White SolidPeso molecolare:364.44NIBR-17
CAS:NIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ with IC50 of 1 nM, 9.2 nM, 9 nM, and 20 nM respectively.Formula:C18H20N8O2Purezza:97.79%Colore e forma:White SolidPeso molecolare:380.4Ref: TM-T22377
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta1mg34,00€1mL*10mM (DMSO)89,00€5mg92,00€Brevianamide F
CAS:Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.Formula:C16H17N3O2Purezza:97.30% - 98.82%Colore e forma:SolidPeso molecolare:283.33SKI V
CAS:SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),Formula:C15H10O4Purezza:98.78%Colore e forma:Yellow SolidPeso molecolare:254.24Ref: TM-T8461
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg281,00€25mg485,00€50mg708,00€100mg1.044,00€1-Deoxynojirimycin hydrochloride
CAS:1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves.Formula:C6H14ClNO4Purezza:99.88%Colore e forma:SolidPeso molecolare:199.633Rigosertib
CAS:Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formula:C21H25NO8SPurezza:99.53%Colore e forma:White SolidPeso molecolare:451.49Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurezza:98% - 99.8%Colore e forma:Yellow SolidPeso molecolare:505.5AZD-7648
CAS:AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.Formula:C18H20N8O2Purezza:99.03% - 99.85%Colore e forma:SolidPeso molecolare:380.4Ref: TM-T7122
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta200mgPrezzo su richiesta1mg38,00€5mg84,00€1mL*10mM (DMSO)93,00€Erucic acid
CAS:Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ).Formula:C22H42O2Purezza:99.64%Colore e forma:White SolidPeso molecolare:338.57Alpelisib
CAS:Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity.Formula:C19H22F3N5O2SPurezza:98% - 99.65%Colore e forma:White SolidPeso molecolare:441.47Ref: TM-T1921
2mg37,00€5mg52,00€1mL*10mM (DMSO)57,00€10mg69,00€25mg82,00€50mg90,00€100mg145,00€500mg424,00€PIK-294
CAS:PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).Formula:C28H23N7O2Purezza:97.22% - >99.99%Colore e forma:SolidPeso molecolare:489.53Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purezza:97.93%Colore e forma:SolidPeso molecolare:270.24Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormula:C26H44NNaO5SPurezza:99.79% - 99.93%Colore e forma:White SolidPeso molecolare:505.69ZSTK474
CAS:PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potentialFormula:C19H21F2N7O2Purezza:98.29% - 99.95%Colore e forma:SolidPeso molecolare:417.41PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formula:C19H16N4O3Purezza:97.79% - 99.30%Colore e forma:Yellow SolidPeso molecolare:348.36GNE-317
CAS:GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).Formula:C19H22N6O3SPurezza:98.42% - 99.54%Colore e forma:White SolidPeso molecolare:414.48Ref: TM-T6845
2mg43,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg92,00€25mg192,00€50mg264,00€100mg339,00€200mg497,00€Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formula:C21H22O11Purezza:98.63% - 99.54%Colore e forma:SolidPeso molecolare:450.39Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purezza:98.76% - 99.92%Colore e forma:SolidPeso molecolare:897.1Ref: TM-T2P2806
1mg46,00€5mg114,00€1mL*10mM (DMSO)161,00€10mg167,00€25mg268,00€50mg408,00€100mg587,00€200mg825,00€TASP0415914
CAS:TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFormula:C13H17N5O3SPurezza:98.14%Colore e forma:SolidPeso molecolare:323.37Ref: TM-T7879
1mg52,00€5mg111,00€1mL*10mM (DMSO)127,00€10mg177,00€25mg299,00€50mg424,00€100mg587,00€200mg792,00€
