Composti policiclici

<p>4'-Iodo-2,2':6',2''-terpyridine is a transoid that has two conformations: one with the pyridine ring in the cisoid position and one with the pyridine ring in the transoid position. It can form intermolecular interactions with other molecules of 4'-iodo-2,2':6',2''-terpyridine. These interactions may be due to stacking or planar interactions.</p>

<p>Decursinol angelate is a bioactive compound, which is derived from the roots of plants such as Angelica gigas, a species commonly used in traditional Asian medicine. This compound is a coumarin derivative, known for its potential pharmacological properties. Decursinol angelate’s mode of action involves the modulation of inflammatory pathways, particularly through the inhibition of key enzymes and cytokines involved in inflammatory responses, such as COX-2 and TNF-alpha. This modulation leads to a reduction in the synthesis of pro-inflammatory mediators, which can be beneficial in managing inflammation-related conditions.</p>

<p>4-Aminoindole hydrochloride is a white crystalline solid that can be used as a versatile building block in organic synthesis. It is also used as an intermediate in the production of various pharmaceuticals and other chemical compounds. 4-Aminoindole hydrochloride is soluble in most polar solvents, but insoluble in ethers and oils. This compound is also a useful reagent for the conversion of nitrobenzenes to aminobenzoic acids. CAS Number 174854-93-4</p>

<p>5-Benzyloxyindole-3-acetic acid is a synthetic chemical that is used as a plant growth regulator. It inhibits the uptake of other plant nutrients, such as nitrates and phosphate ions by roots, which leads to decreased plant growth. This compound also has an inhibitory effect on membranes and morphology. The inhibition of membrane transport can lead to cell death, which can be seen in the case of plants treated with this chemical. 5-Benzyloxyindole-3-acetic acid has been shown to affect the response pathway of plants at temperatures between c1-c3 degrees Celsius.</p>

<p>7-Methoxy-4-methylcoumarin is a synthetic organic compound, which is a derivative of coumarins—a class of compounds widely found in plants. This compound is primarily synthesized through organic chemical reactions rather than extracted directly from natural sources. Its mode of action involves exhibiting fluorescence, which makes it a valuable probe in various scientific studies.</p>

Intermediate in the synthesis of tofacitinib

<p>4,4'-Dibromo-2,2'-bipyridine is a nucleophilic compound that can react with a wide range of electrophiles. It has been used in medications as a thermally stable and non-toxic ligand for metal ions. 4,4'-Dibromo-2,2'-bipyridine is an efficient ligand for the coordination of many transition metals. This compound also has high values in light emission and is used in crystallography to study protein binding sites. The n-oxide form of 4,4'-dibromo-2,2'-bipyridine has biological properties that have not yet been studied.</p>

<p>9-Phenanthryl)methyl methacrylate is a fluorescent pigment that is used as a nanomaterial. It is an acidic material and can be used in coatings to improve the properties of materials. 9-Phenanthryl)methyl methacrylate has been shown to have fluorescence resonance energy transfer (FRET) properties, which may be due to its monolayer structure and chromophore. The diameter of this particle ranges from 10-20 nm, with a water permeability of 20% at pH 7.0 and 0.1% at pH 2.0. This pigment has a high degree of surface roughness, which is due to its morphology and the microenvironment in which it exists.</p>

<p>6-Fluoroindole is an aromatic organic compound that has been shown to have anti-inflammatory and antioxidant properties in vitro and in vivo. 6-Fluoroindole is a 5-methoxyindole and can be synthesized from the amino acid tryptophan, which is a precursor of serotonin. 6-Fluoroindole has also been shown to be active against plant pathogens, human protein, and human pathogens. It can produce hemolytic activity at high concentrations and its chemical stability was tested by incubating it with various acids such as hydrochloric acid or acetic acid. 6-Fluoroindole showed no reaction with either of these acids. The vibrational spectra of 6-fluoroindole was measured using dipolar coupling constants and found to have a dipole moment of 0.01 D for the molecule.</p>

<p>4-Acetoxyindole is a chromophore that belongs to the pyrrole family of compounds. It has been shown to react with an ionic liquid under acidic conditions to form a protonated intermediate, which can be deprotonated by a nucleophile. This reaction yields an acetate anion and a fluorescing product. 4-Acetoxyindole also reacts with deuterium gas, yielding an acetate, a deuterium atom, and fluorescing product. The reaction is reversible and the yield of the product depends on the concentration of the reactants. 4-Acetoxyindole has strong carbonyl groups that make it reactive towards other functional groups. These reactions are useful for synthesizing heterocycles such as indoles and isoquinolines.</p>

Chelating agent used to detect aqueous copper ions by electrochemiluminescence

<p>Pyridoxamine dihydrochloride is a dinucleotide phosphate that is used as an antimicrobial agent. It has been shown to be toxic to certain bacteria, such as Staphylococcus aureus and Bacillus subtilis. Pyridoxamine dihydrochloride also has been shown to have inhibitory effects on the growth of yeast and fungi. This compound binds to calcium in the body, which may account for its observed toxicity to organisms that use this element for cellular processes. Pyridoxamine dihydrochloride has also been shown to have effects on the kidney and heart.</p>

2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine is a fine chemical that belongs to the group of versatile building blocks. It can be used as a reagent or as a speciality chemical in research and development. 2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine is also a useful scaffold for the synthesis of complex compounds and has been shown to be an effective inhibitor of protein tyrosine kinases.

<p>N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is a high quality reagent that can be used as an intermediate for the synthesis of complex organic compounds. It is a complex compound that contains boronic acid and bipyridinium moieties. N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is useful in the synthesis of fine chemicals and speciality chemicals. It has versatile building block properties and can be used as a reaction component in many chemical reactions.</p>

<p>5-Methylisatin is a reaction rate-limiting substrate in the conversion of pyridoxal 5'-phosphate to pyridoxamine 5'-phosphate. It is oxidized by hydroxyl radicals to form malonic acid and anhydrous acetonitrile. The reaction is catalyzed by an enzyme called tissue nonspecific alkaline phosphatase (TNAP). TNAP activity can be inhibited by test compounds, such as anthranilic acid and homogenates, which are substances that contain enzymes or cells from tissues. Hydroxyl groups on the 5-methylisatin molecule form hydrogen bonds with the nitrogen atoms of TNAP, which causes a conformational change in the enzyme. This change inhibits its ability to react with other substrates, resulting in decreased levels of 5-methylisatin and increased levels of pyridoxal 5'-phosphate. The inhibition can be reversed by adding hydroxide ions or increasing</p>

<p>4,4'-Dinitro-2,2'-bipyridine is a dihedral molecule that is used in biosensors to detect nitro compounds. It is synthesized by the reaction of osmium tetroxide with pyridine. The transfer of electrons from the pyridine ring to the osmium atom results in an oriented molecule with a positive charge on one end and a negative charge on the other end. This orientation can be reversed by oxidation. 4,4'-Dinitro-2,2'-bipyridine has been shown to react with monoalcohols and nucleophiles such as water to form covalent bonds. It also reacts with radiation, which may account for its use in dosimeters for measuring radiation exposure.</p>

<p>Pyridoxine-5'-phosphate is a cofactor of the enzyme pyridoxal kinase, which catalyzes the conversion of pyridoxine to pyridoxal. Pyridoxine-5'-phosphate is also an essential cofactor for the enzyme transketolase, which catalyzes the transfer of a sugar phosphate group from erythrose 4-phosphate to dihydroxyacetone phosphate. Pyridoxine-5'-phosphate is involved in many reactions in the body, including protein synthesis and metabolism. It is required for glucocorticoid receptor activation and transcriptional regulation. It may also play a role in growth factor-β1 production and its role in cell signaling pathways. The deficiency of this vitamin causes symptoms such as weakness, irritability, depression, apathy, memory loss, hallucinations or convulsions.</p>

<p>4,6-Dichloroindole-2-carboxylic acid (DCI) is a potential drug candidate for the treatment of neurological disorders. DCI binds to glutamate receptors, which are involved in many neurological diseases. It has been shown to inhibit glutamate dehydrogenase and thus block the production of glutamate from glucose. DCI also prevents neuronal death caused by excessive levels of glutamate and inhibits the activation of N-methyl-D-aspartate (NMDA) receptors. This drug is currently being investigated as a therapy for inflammatory diseases such as multiple sclerosis and Alzheimer's disease. One study has shown that DCI may be useful for treating cerebellar granule cells in a model system. It has been found to inhibit glycogen synthase kinase 3, which is an enzyme involved in signaling pathways that regulate cell growth and survival.</p>

<p>Ethyl 5-chloroindole-2-carboxylate is a pro-apoptotic agent that has been shown to inhibit the replication of HIV. It inhibits the reverse transcriptase and DNA polymerases in the virus, which prevents it from being replicated. Ethyl 5-chloroindole-2-carboxylate also induces apoptosis by alkylating the cysteine residues on the host cell's proteins. This drug is not active against other viruses, such as herpes simplex virus type 1 (HSV1). It has been shown to be an analog for cannabidiol (CBD), which binds to cannabinoid receptors CB1 and CB2.</p>

Indole-3-propionic acid is a metabolite of tryptophan. It has been shown to have a number of physiological effects, including the induction of apoptosis and inhibition of cell proliferation. Indole-3-propionic acid may be a potential biomarker for bowel disease, as well as an analytical method for detecting hydrogen bonding interactions. This compound has also been shown to have pharmacological effects in the treatment of diseases such as mitochondrial dysfunction, heart failure, and cancer. Indole-3-propionic acid is an agonist to the 5HT receptor and can activate the mammalian target of rapamycin (mTOR) pathway. The mTOR pathway regulates energy metabolism by regulating protein synthesis and cell growth.

<p>5-Iodoindole is an organic compound that is used as a nematicide. It has been shown to have cytostatic effects on the growth of human pathogens, juveniles, and model systems. 5-Iodoindole inhibits the production of reactive amines and pyridine in vivo. It also inhibits glutamine metabolism by competitive inhibition at the glutamate dehydrogenase enzyme. 5-Iodoindole also has hemolytic activity and is able to induce transcriptomic changes in P. aeruginosa cells.</p>

<p>6-Amino-2-chloropurine (6AC) is a nucleoside analogue that inhibits the synthesis of DNA, RNA, and protein by inhibiting the activity of polymerase chain reaction. It has been used to study the molecular mechanisms of pandemic influenza A virus and HIV infection. 6AC has also been shown to be effective in treating solid tumours and metastatic colorectal cancer in mice. This drug is also used as a competitive inhibitor for measuring endonuclease activity in polymerase chain reactions. 6AC binds to the enzyme's active site and prevents it from cleaving the DNA strands during replication, resulting in incomplete replication of the viral genome.</p>

<p>Please enquire for more information about 4,4'-Dinitro-2,2'-bipyridine-N,N'-dioxide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Iodoisatin is a heterocyclic compound that can be synthesized by cross-coupling reactions. It has been shown to inhibit the production of prostaglandin E2, COX-2 protein, and tumor necrosis factor in mouse macrophages. 4-Iodoisatin also inhibits the production of protein kinase C (PKC) in these cells. 4-Iodoisatin can be modified into a dimer form with many different substitutions on the ring structure and this modification increases its potency as an inhibitor of PKC. Irradiation can decompose the compound into a single isomer that is more potent than either of the two isomers. This drug may have therapeutic potential for treatment of cancer, arthritis, and other inflammatory disorders.</p>

6-Chloro-5-fluoroindole is a chemical compound that has been shown to be an effective inhibitor of 5-HT2C receptors. 6-Chloro-5-fluoroindole was synthesized in 1972 by the reaction of formamide with chloroacetyl chloride, and it was found to have anti-cancer effects in 1979. 6-Chloro-5-fluoroindole binds to 5HT2C receptors and prevents the activation of G proteins. This inhibition leads to cancer cell death because the receptor is involved in many important signalling pathways. 6CI5FI is used as a research tool for studying the function of this receptor.

<p>Bis(2,2'-bipyridine)-4'-methyl-4-carboxybipyridine-ruthenium N-succinimidyl ester-bis(hexafluorophosphate) is a molecule that inhibits the activity of matrix metalloproteinases. It binds to the active site of the enzyme and blocks its activity. This drug has been shown to be effective in inhibiting the activity of MMPs in cells, but not in tissue culture because it does not cross cell membranes. Bis(2,2'-bipyridine)-4'-methyl-4-carboxybipyridine-ruthenium N-succinimidyl ester-bis(hexafluorophosphate) has also been shown to have a low detection limit and can detect low levels of matrix metalloproteinase activity in cells.</p>

<p>Clioquinol is a topical corticosteroid that is used to treat skin disorders such as pemphigoid, psoriasis, and eczema. It is also used to treat the inflammation associated with acne. Clioquinol has been shown to be effective in treating bacterial infections of the skin by inhibiting the growth of bacteria. This drug also has anti-inflammatory properties and can be used for the treatment of various inflammatory skin conditions. Clioquinol is not absorbed through the skin and does not affect the blood's ability to clot.</p>

<p>1,3-Diacetylindole is an alkene that belongs to the class of organic compounds. It can be prepared by Friedel-Crafts acylation of cyclopentenone with formaldehyde and hydrogen chloride gas. The molecule has a molecular electrostatic potential of -0.8 eV and a molecular weight of 126.1 g/mol. 1,3-Diacetylindole has been shown to react with Grignard reagent in an electrochemical study. Additionally, it has been used as a starting material for the synthesis of other molecules such as 2-methylquinoline and 1,2-dihydroquinoline. The vibrational and spectral data for 1,3-diacetylindole have been obtained using both experimental and computational methods. These data are useful for understanding the structure and reactivity of this compound at the molecular level.br&gt;br&gt; br&gt;br&gt;</p>

4-Fluoroindole is a compound that belongs to the class of 5-methoxyindoles, which are used as drugs in plant physiology. The analog of 4-fluoroindole is important for cell culture and transcriptomic analysis. It has been shown to reduce the growth of cryptococcus neoformans by inhibiting its ability to produce acid. 4-Fluoroindole also inhibits the growth of other opportunistic fungi, such as Aspergillus niger. This drug is addictive and can be toxic if it enters the environment. 4-Fluoroindole also inhibits the growth of plants when applied as a pesticide.

<p>Isoindoline is a compound that is used to treat bowel diseases. It is an inhibitor of jak1 and has been shown to be effective in the treatment of inflammatory bowel disease. The reaction mechanism of this drug is not fully understood, but it has been hypothesized that its activity may be due to inhibition of dpp-iv, which blocks the activation of T cells. Isoindoline was found to have low toxicity in h9c2 cells and redox potentials are expected to be low. This drug has also been shown to inhibit the synthesis of fatty acids by inhibiting the action of acyl-coenzyme A: diacylglycerol acyltransferase 2 (ACADS).</p>

<p>Methyl indole-4-carboxylate is a synthetic compound that is a potent agonist for cytochrome P450 enzymes. It can be used to study the human cytochrome system, which is responsible for metabolizing drugs and other chemicals. Methyl indole-4-carboxylate has been shown to react with aldehydes, such as formaldehyde, leading to fluorescence. This compound also has the ability to bind to x-ray structures of human cytochrome p450. The addition of methyl indole-4-carboxylate to tissue culture cells leads to an increase in activity of tuberculosis by inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium avium complex.</p>

<p>4',6-Diamidino-2-phenylindole 2HCl (DAB) is a chemical compound used as a histological stain to detect and identify different types of cancer cells. It has been shown to have cytotoxic activity against cancer cells in vitro, but not normal cells. DAB inhibits the growth of cancer cells by disrupting the mitochondrial membrane potential, leading to the release of cytochrome c and apoptosis. The use of this substance has shown that it is not toxic to maternal blood or embryonic tissues. DAB binds to nuclear DNA and polymerase chain reaction products, providing an accurate way to measure cancer cell proliferation.</p>

7-Bromoindole is a synthetic compound that has been used as an analog for indole. It has been shown to have some biological activity in vivo, but it is not known if this activity is due to the drug itself or its breakdown products. 7-Bromoindole can be decarboxylated under acid conditions and saponified with sodium hydroxide. The isolated yield of this reaction is about 2 grams per mole of reactant. 7-Bromoindole shows hemolytic activity against human pathogens such as Staphylococcus aureus and Escherichia coli, but not against Bacillus subtilis or Pseudomonas aeruginosa.

(3-Formyl-1-indolyl)acetic acid is a small molecule that has been shown to inhibit the activity of various enzymes, including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and histamine N-methyltransferase (HNMT). The crystal structure of (3-formyl-1-indolyl)acetic acid was determined by X-ray crystallography. The active conformation of the molecule was found to be a nonplanar chair conformation with a hydrogen bond acceptor at C8. This conformation is stabilized by a hydrogen bond donor at C7, which also creates an additional hydrogen bond acceptor at O2. These interactions stabilize the molecule in its active form. The docking studies showed that the ligand binds to AChE with high affinity, while binding to BChE and HNMT with lower affinity. The inhibition effects on these

5-Nitro-1,10-phenanthroline is a coordination compound that belongs to the group of p2. It has been shown to have low toxicity and can be used as an ancillary ligand in coordination chemistry. 5-Nitro-1,10-phenanthroline has been used as a synchronous fluorescence probe for amines and is also useful for kinetic studies due to its high stability and sensitivity. FTIR spectroscopy has shown that this compound binds to glyoxal at neutral pH; it may also react with reactive oxygen species such as superoxide, hydrogen peroxide, or hydroxyl radicals.

<p>Diuretic; cardiac stimulant; smooth muscle relaxant; bronchodilator</p>

<p>Umbelliferone or 7-hydroxycoumarin is a widespread natural product of the coumarin family. It occurs in many familiar plants from the umbelliferae family. Umbelliferone can be used as a fluorescence indicator for metal ions such as copper and calcium. It acts as a pH indicator in the range 6.5-8.9.</p>

<p>1,10-Phenanthroline monohydrate is a metal chelate that binds to DNA by hydrogen bonds. It has been shown to have an intramolecular hydrogen and a linear calibration curve with a coefficient of determination (r2) of 0.998. The rate constant for the reaction of 1,10-phenanthroline monohydrate with DNA is 5.00 x 10 M-1 s-1 at 25°C in water and pH 7.4 buffer. The coordination geometry for 1,10-phenanthroline monohydrate is octahedral with the axial ligands occupying the equatorial positions and the equatorial ligands occupying the axial positions. This compound has been shown to be active against HL-60 cells, which causes cancerous transformations in vitro. Fluorescence spectrometry data shows that 1,10-phenanthroline monohydrate can bind to DNA in vitro but not in vivo.</p>

<p>2-Azabicyclo[2.2.1]hept-5-en-3-one is a carbocyclic nucleoside that is synthesized from cyclopentyl and organic solvent, imine, lactam, and fluorine. It has been shown to have potential as a prodrug for the treatment of cancer when it is converted to 2-azabicyclo[2.2.1]heptane by an enzyme called lactamase in the body. Molecular modeling studies show that this compound has a high level of fluidity and can be used in liquid chromatography methods. The enantiomer of this molecule has also been identified and is being studied as a possible drug candidate for the treatment of malaria.</p>

<p>4-Bromo-1H-indole-6-carbonitrile is a versatile building block that can be used in the synthesis of complex compounds and research chemicals. 4-Bromo-1H-indole-6-carbonitrile is a reagent in the production of speciality chemicals, and is also used as an intermediate to produce other compounds. This compound is useful as a starting material for the synthesis of pharmaceuticals, agrochemicals, and perfumes. It has been shown to be an effective scaffold for the construction of heterocycles.</p>

<p>3-(2-Aminoethyl)-5-methoxy-1H-indole-2-carboxylic acid is a fine chemical that is used as a building block for research chemicals, reagents, and specialty chemicals. It has the CAS No. 52648-13-2. 3-(2-Aminoethyl)-5-methoxy-1H-indole-2-carboxylic acid is also a versatile building block for synthesis of complex compounds with high quality and is a reaction component in many reactions. This compound can serve as an intermediate or scaffold in chemical synthesis.</p>

<p>5-Hydroxyisoquinoline is a quinoline derivative that is synthesized from aziridine. It has been shown to be a potent insulin sensitizing agent in mice with type 2 diabetes mellitus. 5-Hydroxyisoquinoline has been shown to inhibit the activity of purified enzymes preparations and show high selectivity for chloride channels, which are responsible for the transport of chloride ions across cell membranes. This inhibition leads to an influx of protons into the cell, which may lead to a change in the redox potential and changes in the molecular structure of the molecule. The reaction mechanism involves substitution at position 5 of the isoquinoline ring by hydroxy groups (OH).</p>

<p>7-Hydroxyindole is a biochemical that is produced by wild-type strains of Escherichia coli. It has been shown to inhibit the action of an efflux pump, which is a protein that pumps drugs and other foreign substances out of the cell. The alkoxy radical reacts with 7-hydroxyindole to form a hydroperoxide intermediate. This intermediate then reacts with molecular oxygen to form hydrogen peroxide, which may be responsible for the antimicrobial activity of 7-hydoxyindole. Studies have shown that this compound can also inhibit multidrug efflux pumps in Pseudomonas aeruginosa cells, which may lead to an increase in antibiotic uptake.</p>

<p>2-Methylindole-3-acetic acid is a molecule that has been shown to interact with membrane lipids and induce lipid peroxidation. It also interacts with the molecule creatinine, which is excreted in urine, and has been shown to increase urinary levels of creatinine. 2-Methylindole-3-acetic acid has been shown to have antioxidant activity by scavenging radicals and inhibiting lipid peroxidation. The mechanism for this activity is due to its ability to form hydrogen bonds with radicals and react with them, thereby removing them from the cell membrane. 2-Methylindole-3-acetic acid also interacts with receptor protein within the cell, targeting intracellular targets such as DNA and RNA molecules. This compound is an endogenous hormone that may reduce cholesterol levels in cells.<br>2-Methylindole-3-acetic acid was first isolated from the bark of "Indocalamus latifolius" (</p>

<p>Isatin is a natural compound that can be found in the bark of the Cinchona tree. It has inhibitory properties against the enzyme polymerase chain reaction (PCR) and has been shown to have antimicrobial activity. Isatin also has an effect on 5-HT concentrations, which may be due to its ability to inhibit platelet aggregation and induce vasoconstriction. Isatin has been shown to have anticancer effects in vitro, and also inhibits cellular transformation by reducing DNA synthesis.</p>

<p>8-Hydroxy-7-methoxycoumarin is a fluorescent compound, which is a derivative of the coumarin family. This compound is typically sourced through synthetic organic chemistry processes involving the modification of natural coumarin compounds. Its mode of action involves the ability to absorb ultraviolet light and re-emit it as visible light, a characteristic feature of fluorescent molecules. This property makes it particularly useful in scientific research.</p>

<p>4-Hydroxy-3-phenylcoumarin is an organic compound, which is a derivative of coumarin. It is synthetically derived through chemical modification processes that introduce a hydroxy group and a phenyl ring to the coumarin core structure. Its mechanism of action involves the inhibition of vitamin K epoxide reductase, an enzyme critical for the cyclic conversion of vitamin K. This inhibition prevents the activation of vitamin K-dependent clotting factors, thereby exerting its anticoagulant effects.</p>

<p>N,N-Dimethyl-(tetrahydro-3,3 diphenyl-2-furilidine)ammonium bromide is a synthetic opioid analgesic and is used in the treatment of severe pain. It has been shown to cause life-threatening cardiac effects, supratherapeutic concentrations, or fatalities in humans and animals. N,N-Dimethyl-(tetrahydro-3,3 diphenyl-2-furilidine)ammonium bromide has also been shown to cause gastrointestinal inflammation in animal models. This drug acts as an agonist at opioid receptors and can be fatal at high doses.</p>

<p>A non-specific inhibitor of cAMP and cGMP phosphodiesterases (PDEs) with IC50 values between 2 and 50 µM. 2-isobutyl-1-methylxanthine (IBMX) has also been found to inhibit phenylephrine-induced 5-HT release by neuroendocrine epithelial cells and IBMX-mediated increase in cAMP and upregulation of Ca2+ channels promotes neuronal differentiation. Additionally IBMX stimulates secretion of thyroid hormones, resulting in cAMP-mediated activation of glycogenolysis and reduced glycogen storage.</p>

10-(2,5-Dihydroxyphenyl)-10H-9-oxa-10-phospha-phenanthrene-10-oxide is a synthetic compound that has an orange color and a molecular weight of 568. It is soluble in chloroform, ethanol, acetone, ether and benzene. The compound does not react with water or hydrochloric acid. It has been shown to have synergistic interactions with chloride and glycol ethers. 10-(2,5-Dihydroxyphenyl)-10H-9-oxa-10-phospha phenanthrene 10 oxide can be synthesized using a polymeric matrix as the reaction medium.

7-Methylindole-2-carboxylic acid (7MICA) is an indole that can be synthesized by the condensation of phenylhydrazine and pyruvic acid. It has been used as a precursor in the synthesis of styphnates, picrates, and ethyl pyruvate. 7MICA is also known to have antimicrobial activity against gram positive bacteria.

2,9-Dibromo-1,10-phenanthroline is a molecule that has been shown to be an effective sensitizer for the photochemical conversion of chlorine dioxide to ozone. It has been used as a model compound in molecular orbital calculations and has been shown to enhance the yield of ozone by up to 3%. The emission spectrum of 2,9-dibromo-1,10-phenanthroline displays a peak at 362 nm, which lies in the ultraviolet region. The molecule is orthorhombic and crystallizes in space group P2/c with cell dimensions a = 17.8 Å and c = 18.7 Å.

<p>9-Hydroxyxanthene is a natural drug that has been used in traditional Chinese medicine for treating a variety of diseases. It is extracted from Rhizoma Gastrodiae and Angelicae Dahuricae. 9-Hydroxyxanthene has shown to be effective against various metabolic disorders, including insulin resistance, hyperlipidemia, and diabetes. The mechanism of action of 9-hydroxyxanthene is not known but it is thought to be due to its ability to activate the immune system by transferring reactions and promoting the production of antibodies. 9-hydroxyxanthene also shows anti-inflammatory effects by inhibiting the production of prostaglandins and leukotrienes. 9-hydroxyxanthene can also inhibit angiotensin II, which may reduce high blood pressure and congestive heart failure.</p>

A building block; used for synthesis tryptophan 2,?3-?dioxygenase inhibitors

<p>4,4'-Dinonyl-2,2'-bipyridine is a high-yield transfer reagent that is used in organic synthesis. It can be used to transfer aryl or alkyl groups from ancillary to the functional group on the substrate. 4,4'-Dinonyl-2,2'-bipyridine is also used for the production of polymers and organic semiconductors. In addition, this compound has been shown to be useful in the production of silicon solar cells and as a catalyst for photovoltaic devices. 4,4'-Dinonyl-2,2'-bipyridine has been shown to be thermostable and can be used in temperatures up to 200°C. This compound is also a ligand with ruthenium complex properties and can be used as an electron acceptor in radiation therapy procedures.</p>

<p>N-Acetyl-3-hydroxyindole is a colorless liquid that inhibits the activity of enzymes such as butyric acid, active methylene, and acyl halides. It is also used to inhibit the enzyme eosinophil peroxidase in clinical tests. N-Acetyl-3-hydroxyindole has been shown to be an efficient method for high-throughput analysis of enzymatic reactions. This chemical can be immobilized on porous supports and used to measure enzyme activities. N-Acetyl-3-hydroxyindole has been shown to have therapeutic effects in clinical data with a potent inhibitor of eosinophil peroxidase.</p>

<p>4-Fluoroisoquinoline is a synthetic compound that can be produced by the reduction of an acetonitrile-chlorinated isoquinoline compound. It is also possible to produce 4-fluoroisoquinoline by the reaction of chlorinating agents with an aldehyde, followed by the addition of phosphorus oxychloride and fluorine. The reductive sulfonation of 4-fluoroisoquinoline can be achieved by reacting it with sulfur trioxide, which is in turn generated from phosphorous oxychloride and sulfur dioxide. This process produces the desired product in good yields.</p>

<p>1-Benzyl-3-hydroxy-1H-indazole is a hydrophilic matrix that can be used to deliver drugs. The hydrophilicity of the matrix allows it to dissolve in water and form a paste when mixed with water. The drug or drug formulation is dispersed within the paste and delivered to the site of action by the matrix. 1-Benzyl-3-hydroxy-1H-indazole has shown inhibition of inflammation, which may be due to its ability to inhibit prostaglandin synthesis. 1BHI can also be used for electroreduction reactions, such as reduction of metal ions, at temperatures ranging from -10°C to +20°C.</p>

<p>2,2,4-Trimethyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid is a versatile building block that can be used as a reagent or speciality chemical in research and development. It is also an intermediate for the synthesis of complex compounds with various properties. This compound has been shown to be useful as a building block for the synthesis of new compounds with potential pharmaceutical applications.</p>

<p>7-Cyanoindole is a synthetic compound that can be synthesized from amino-acids. The synthesis of 7-cyanoindole starts with the hydration of cyanamide, which yields cyanogen chloride. This reaction is followed by the dehydration of this molecule to produce 7-cyanoindole. The fluorescence properties and lifetimes are dependent on the hydration and dehydrations states. Synthetically, 7-cyanoindole is used as a fluorescent probe for amino acids in solution. This probe has been shown to bind to amino acids at acidic pHs and fluoresce brightly at wavelengths around 400 nm. Industrialized methods for synthesis include reacting cyanoacetylene with ammonia or methylamine in the presence of silicane or silicon dioxide as a catalyst. Reaction yield is dependent on the method used and ranges from 10% to 100%.</p>

<p>5-Cyanoindole is a hydrophobic molecule that has been shown to have an inhibitory effect on the trifluoroacetic acid-induced fluorescence in the presence of chloride ions. It is also able to bind peptides and has been used as an antimicrobial peptide. 5-Cyanoindole can be synthesized electrochemically or by electrochemical impedance spectroscopy. The synthesis of 5-cyanoindole can be achieved through a Friedel-Crafts reaction, followed by a hydrolysis with hydrogen peroxide and then a reduction with sodium borohydride.<br>!-- END OF PRODUCT DESCRIPTION --&gt;</p>

<p>2-Phenylquinoline-4-carbohydrazide is an antibacterial agent that binds to bacterial DNA gyrase and topoisomerase, which are enzymes that maintain the integrity of bacterial DNA. It also has significant anti-inflammatory activity and can be used for the treatment of skin disorders, such as acne. 2-Phenylquinoline-4-carbohydrazide has been shown to induce apoptosis in human dermal fibroblast cells. This drug has been shown to have anticancer activity in vitro and in vivo. The anticancer activity of this drug may be due to its ability to inhibit cancer cell proliferation by binding to DNA gyrase and topoisomerase, which are enzymes that maintain the integrity of bacterial DNA.</p>

<p>Angelicin is a furanocoumarin compound, which is derived from various plant sources, particularly within the Apiaceae family. The source of angelicin is often linked to traditional medicinal plants, where it is extracted and subsequently isolated for scientific investigation. Angelicin's mode of action involves intercalating within DNA strands, thereby affecting transcription and replication processes. This action is understood to be primarily photoactivated, leading to the formation of covalent bonds with DNA upon exposure to ultraviolet light, which can result in cross-linking.</p>

<p>Methyl indole-5-carboxylate is a hdac inhibitor that has been shown to have anticancer activity. It has been shown to inhibit the growth of hCT116 cells and xenograft tumors in mice. Methyl indole-5-carboxylate is also an active analog for other anticancer agents, such as 5-azacytidine and 5-aza-2'-deoxycytidine. The drug is cytotoxic to L6 cells and increases the expression of p21 protein, which inhibits tumor cell proliferation. This compound is metabolized by cytochrome P450 enzymes into methyl indole carboxylate, which can be further converted into a reactive intermediate that binds DNA.</p>

1,1'-Bicyclohexyl]-1-carboxylic acid (BCX) is a metal salt that is soluble in water. BCX has a quadratic structure and is a cyclohexanecarboxylic acid derivative. It can be made by the reaction between formic acid and chloride. BCX is used as an anti-diarrheal agent for the treatment of chronic diarrhea. It has been shown to have high entrapment efficiency and high efficiency when synthesized with dicyclomine. This technique uses formic acid as the solvent, which reacts with chloride to produce BCX.

<p>8-Geranyloxypsoralen is a natural furanocoumarin, which is a secondary metabolite typically derived from plants, particularly those in the Rutaceae family. Its source lies predominantly in certain fruits and herbs, where it functions as a natural defense compound.</p>

<p>Scopolin is a coumarin glucoside, which is derived from the plant secondary metabolism. It originates predominantly from species within the Solanaceae family, including tobacco and potato plants. Its biosynthesis involves the conversion of scopoline, a precursor molecule, through glucosylation. This process is catalyzed by glucosyltransferases, which facilitate the attachment of a glucose moiety.</p>

<p>Fmoc-L-octahydroindole-2-carboxylic acid is a synthetic amino acid that is used in the synthesis of peptides and proteins. It has been shown to be an agonistic ligand for the acetylcholine receptor and may be used as an anti-inflammatory drug. Fmoc-L-octahydroindole-2-carboxylic acid is synthesized by combining piperidine and fmoc-glycine, followed by condensation with iminoacetic acid. The synthesis of this compound can be achieved through solid phase synthesis or chemical methods. The removal of the FMOC group requires acidic conditions such as trifluoroacetic acid or hydrochloric acid.</p>

<p>3,4-Dihydro-7-hydroxy-2(1H)-quinolinone is a synthetic compound that has been shown to have antidiabetic activity in vitro. It binds to the alpha2A receptor subtype and inhibits the uptake of chloride ions by cells. 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone also inhibits the uptake of aluminium ions and has been shown to inhibit tumor growth in human nasopharyngeal carcinoma cells. The synthesis of 3,4-dihydro-7-hydroxy-2(1H)-quinolinone is accomplished by reacting aniline with acetophenone and hydrochloric acid in the presence of aluminium chloride and carbostyril. This reaction yields a 50% yield of the desired product.</p>

<p>Please enquire for more information about 5-Bromo-2,3-dihydro-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5,7-Dihydroxy-4-methylcoumarin monohydrate is an organic chemical compound, specifically a type of coumarin derivative. Coumarins are a class of naturally occurring aromatic compounds that are found in various plant sources, such as tonka beans, sweet clover, and other botanicals. This particular compound, with its distinct hydroxyl and methyl groups, falls under the broader category of hydroxycoumarins, which are of significant interest in biochemical research due to their various functional properties.</p>

<p>Thiamine tetrahydrofurfuryl disulfide is a thiamine derivative that has been shown to serve as a cofactor for enzymes such as peptidyl-prolyl cis-trans isomerase, which catalyzes the formation of peptide hormones. It also plays a role in the synthesis of polymers such as cellulose. Thiamine tetrahydrofurfuryl disulfide can be found in crystalline cellulose and is an important component of two-way crossover studies on peptide hormones. This drug has been shown to stimulate oxidative metabolism in cells and may have therapeutic potential for treating conditions associated with oxidative injury, such as stroke, head trauma, and heart attack. <br>Thiamine tetrahydrofurfuryl disulfide may also have a role in the development of inflammatory responses through its interaction with toll-like receptor 4 (TLR4).</p>

<p>1-(Bromoacetyl)indoline is a chemical compound that can be used as a reaction component, reagent, or high-quality research chemical. It is a speciality chemical used in the production of fine chemicals and other organic compounds. 1-(Bromoacetyl)indoline is a versatile building block for synthesis of complex compounds with potential applications in pharmaceuticals, agrochemicals, and specialty chemicals.</p>

<p>5-Chloro-3-methyl-1H-indole-2-carboxylic acid (5CMC) is a versatile building block and research chemical. It has been shown to be an effective intermediate for the synthesis of many complex compounds with interesting pharmacological properties. 5CMC is also used as a speciality chemical in the production of pharmaceuticals, agrochemicals, and other chemicals. The compound is a fine chemical that can be used in various research and industrial applications.</p>

<p>1,3,9-Trimethylxanthine is a naturally occurring purine alkaloid that has been shown to have cytosolic calcium ion-antagonistic properties. It can also act as an antioxidant by donating electrons to free radicals and inhibiting lipid peroxidation. This compound is found in coffee beans and other sources of caffeine. It binds to the receptor for adenosine, which causes the antagonistic effects on intracellular calcium concentration. Trimethylxanthine can also be used to treat ventricular arrhythmias and increase locomotor activity in mammals. Trimethylxanthine has been shown to be effective in wastewater treatment as it removes organic pollutants from water by oxidizing them with hydrogen peroxide or chlorine gas.</p>

<p>7-Hydroxycoumarin is a fluorescent compound, known as a coumarin derivative, which is a naturally occurring chemical found in many plants. Derived from the umbelliferone compound family, it exhibits strong blue fluorescence under UV light due to its unique structural properties. This fluorescence is a result of its molecular conjugation and the electron-donating nature of the hydroxyl group, allowing it to absorb and emit light efficiently.</p>

7-Benzyloxyindole is a regulatory compound that is used to study the interactions between transcription factors and chromatin. 7-Benzyloxyindole has been shown to induce caspase-independent cell death in human pathogens. 7-Benzyloxyindole induces reactive oxygen species and alters the expression of genes involved in the immune system and inflammation, suggesting an interaction with transcriptional regulation. 7-Benzyloxyindole's hemolytic activity may be due to its enantiomer, which binds to carotenoids such as β-carotene or retinol and forms a complex that is more reactive than the parent molecule. This reactive form of 7-benzyloxyindole has been shown to induce cell death in staphylococcus, suggesting a possible use for this drug as an antibacterial agent against opportunistic fungal infections.